Download or read book Computational Anatomy Based on Whole Body Imaging written by Hidefumi Kobatake and published by Springer. This book was released on 2017-06-14 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with computational anatomy, an emerging discipline recognized in medical science as a derivative of conventional anatomy. It is also a completely new research area on the boundaries of several sciences and technologies, such as medical imaging, computer vision, and applied mathematics. Computational Anatomy Based on Whole Body Imaging highlights the underlying principles, basic theories, and fundamental techniques in computational anatomy, which are derived from conventional anatomy, medical imaging, computer vision, and applied mathematics, in addition to various examples of applications in clinical data. The book will cover topics on the basics and applications of the new discipline. Drawing from areas in multidisciplinary fields, it provides comprehensive, integrated coverage of innovative approaches to computational anatomy. As well, Computational Anatomy Based on Whole Body Imaging serves as a valuable resource for researchers including graduate students in the field and a connection with the innovative approaches that are discussed. Each chapter has been supplemented with concrete examples of images and illustrations to facilitate understanding even for readers unfamiliar with computational anatomy.
Download or read book Multidisciplinary Computational Anatomy written by Makoto Hashizume and published by Springer Nature. This book was released on 2021-11-30 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume thoroughly describes the fundamentals of a new multidisciplinary field of study that aims to deepen our understanding of the human body by combining medical image processing, mathematical analysis, and artificial intelligence. Multidisciplinary Computational Anatomy (MCA) offers an advanced diagnosis and therapeutic navigation system to help detect or predict human health problems from the micro-level to macro-level using a four-dimensional, dynamic approach to human anatomy: space, time, function, and pathology. Applying this dynamic and “living” approach in the clinical setting will promote better planning for – and more accurate, effective, and safe implementation of – medical management. Multidisciplinary Computational Anatomy will appeal not only to clinicians but also to a wide readership in various scientific fields such as basic science, engineering, image processing, and biomedical engineering. All chapters were written by respected specialists and feature abundant color illustrations. Moreover, the findings presented here share new insights into unresolved issues in the diagnosis and treatment of disease, and into the healthy human body.
Download or read book Intelligent Orthopaedics written by Guoyan Zheng and published by Springer. This book was released on 2018-10-10 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces readers to the latest technological advances in the emerging field of intelligent orthopaedics. Artificial intelligence and smart instrumentation techniques are now revolutionizing every area of our lives, including medicine. The applications of these techniques in orthopaedic interventions offer a number of potential benefits, e.g. reduced incision size and scarring, minimized soft tissue damage, and decreased risk of misalignment. Consequently, these techniques have become indispensable for various orthopaedic interventions, which has led to the emerging field of intelligent orthopaedics. Addressing key technologies and applications, this book offers a valuable guide for all researchers and clinicians who need an update on both the principles and practice of intelligent orthopaedics, and for graduate students embarking on a career in this field.
Download or read book Computational Methods of Modeling Vascular Geometry and Tracking Pulmonary Motion from Medical Images written by Guanglei Xiong and published by Stanford University. This book was released on 2011 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern anatomical medical imaging technologies, such as computed tomography and magnetic resonance, capture structures of the human body in exquisite detail. Computational anatomy is a developing discipline to extract and characterize the anatomy from images. Unfortunately, anatomical images do not reveal the functional behavior. Computational physiology shows great potential to link the structure-function relationship by considering both the anatomical information and the physical governing laws. The simulated physiology can be used to assess physiological states, and more importantly predict the outcomes of interventions. On the other hand, advances in the functional imaging techniques provide measured physiology information and should be utilized together with computational physiology. In the theme of computational anatomy and physiology, this dissertation describes computational methods of modeling vascular geometry for image-based blood flow computation and tracking pulmonary motion for image-guided radiation therapy. Blood flow computation is a useful tool to quantify in vivo hemodynamics. The essential first step is to model vascular geometry from medical imaging data. I have developed a new workflow for this task. The geometric model construction is based on 3D image segmentation and geometric processing. To represent the topology of the constructed model, I have developed a novel centerline extraction method. To account for compliant vessels, methods to assign spatially-varying mechanical properties of the vessel wall are also developed. The workflow greatly increases the modeling efficiency. The combination of the patient-specific geometry and wall deformation can enhance the fidelity of blood flow simulation. Image-based blood flow computation also holds great promise for device design and surgical procedure evaluation. Next, I have developed novel virtual intervention methods to deploy stents or stent grafts to patient-specific pre-operative geometric models constructed from medical images. These methods enable prospective model construction and may be used to evaluate the outcomes of alternative treatment options. Respiratory motion is closely related to the physiology of the lung. Finally, I have developed a novel framework to track patient-specific pulmonary motion from 4D computed tomography images. A large set of vascular junction structures in the lung are identified as landmarks and tracked to obtain their motion trajectories. This framework can provide accurate motion information, which is important in radiation therapy to reduce healthy tissue irradiation while allowing target dose escalation. This work demonstrates the importance of the geometry and motion modeling tools in computational anatomy and physiology. Accurate physiological information, whether simulated or measured, will benefit the diagnosis and treatment of various diseases.
Download or read book Cases on Virtual Reality Modeling in Healthcare written by Tang, Yuk Ming and published by IGI Global. This book was released on 2021-12-17 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtual reality (VR) provides immersive stereoscopic visualization of virtual environments, and the visualization effect and computer graphics are critical to enhancing the engagement of participants and achieving optimal education and training effectiveness. Constructing realistic 3D models and scenarios for a specific application of VR simulation is no easy task. There are many different tools for 3D modeling. However, many of the modeling tools are used for manufacturing and product design applications and have advanced features and functions which may not be applicable to different levels of users and various specializations. Cases on Virtual Reality Modeling in Healthcare introduces the use of Blender for VR 3D modeling, demonstrates healthcare applications, and examines potential uses in modeling, dressing, and animation in healthcare. Covering a range of topics such as cross reality, rehabilitation games, and augmented reality, this book is ideal for engineers, industry professionals, practitioners, researchers, academicians, instructors, and students.
Download or read book Medical Imaging Systems Technology Methods in general anatomy written by Cornelius T. Leondes and published by World Scientific. This book was released on 2005 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach.Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage.As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.
Download or read book Recent Advances and the Future Generation of Neuroinformatics Infrastructure written by Xi Cheng and published by Frontiers Media SA. This book was released on 2015-12-11 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: The huge volume of multi-modal neuroimaging data across different neuroscience communities has posed a daunting challenge to traditional methods of data sharing, data archiving, data processing and data analysis. Neuroinformatics plays a crucial role in creating advanced methodologies and tools for the handling of varied and heterogeneous datasets in order to better understand the structure and function of the brain. These tools and methodologies not only enhance data collection, analysis, integration, interpretation, modeling, and dissemination of data, but also promote data sharing and collaboration. This Neuroinformatics Research Topic aims to summarize the state-of-art of the current achievements and explores the directions for the future generation of neuroinformatics infrastructure. The publications present solutions for data archiving, data processing and workflow, data mining, and system integration methodologies. Some of the systems presented are large in scale, geographically distributed, and already have a well-established user community. Some discuss opportunities and methodologies that facilitate large-scale parallel data processing tasks under a heterogeneous computational environment. We wish to stimulate on-going discussions at the level of the neuroinformatics infrastructure including the common challenges, new technologies of maximum benefit, key features of next generation infrastructure, etc. We have asked leading research groups from different research areas of neuroscience/neuroimaging to provide their thoughts on the development of a state of the art and highly-efficient neuroinformatics infrastructure. Such discussions will inspire and help guide the development of a state of the art, highly-efficient neuroinformatics infrastructure.
Download or read book Computational Methods of Modeling Vascular Geometry and Tracking Pulmonary Motion from Medical Images written by Guanglei Xiong and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern anatomical medical imaging technologies, such as computed tomography and magnetic resonance, capture structures of the human body in exquisite detail. Computational anatomy is a developing discipline to extract and characterize the anatomy from images. Unfortunately, anatomical images do not reveal the functional behavior. Computational physiology shows great potential to link the structure-function relationship by considering both the anatomical information and the physical governing laws. The simulated physiology can be used to assess physiological states, and more importantly predict the outcomes of interventions. On the other hand, advances in the functional imaging techniques provide measured physiology information and should be utilized together with computational physiology. In the theme of computational anatomy and physiology, this dissertation describes computational methods of modeling vascular geometry for image-based blood flow computation and tracking pulmonary motion for image-guided radiation therapy. Blood flow computation is a useful tool to quantify in vivo hemodynamics. The essential first step is to model vascular geometry from medical imaging data. I have developed a new workflow for this task. The geometric model construction is based on 3D image segmentation and geometric processing. To represent the topology of the constructed model, I have developed a novel centerline extraction method. To account for compliant vessels, methods to assign spatially-varying mechanical properties of the vessel wall are also developed. The workflow greatly increases the modeling efficiency. The combination of the patient-specific geometry and wall deformation can enhance the fidelity of blood flow simulation. Image-based blood flow computation also holds great promise for device design and surgical procedure evaluation. Next, I have developed novel virtual intervention methods to deploy stents or stent grafts to patient-specific pre-operative geometric models constructed from medical images. These methods enable prospective model construction and may be used to evaluate the outcomes of alternative treatment options. Respiratory motion is closely related to the physiology of the lung. Finally, I have developed a novel framework to track patient-specific pulmonary motion from 4D computed tomography images. A large set of vascular junction structures in the lung are identified as landmarks and tracked to obtain their motion trajectories. This framework can provide accurate motion information, which is important in radiation therapy to reduce healthy tissue irradiation while allowing target dose escalation. This work demonstrates the importance of the geometry and motion modeling tools in computational anatomy and physiology. Accurate physiological information, whether simulated or measured, will benefit the diagnosis and treatment of various diseases.
Download or read book Handbook of Small Animal Imaging written by George C. Kagadis and published by CRC Press. This book was released on 2016-03-16 with total page 869 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.
Download or read book Bayesian Estimation and Inference in Computational Anatomy and Neuroimaging Methods Applications written by Xiaoying Tang and published by Frontiers Media SA. This book was released on 2019-08-22 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Anatomy (CA) is an emerging discipline aiming to understand anatomy by utilizing a comprehensive set of mathematical tools. CA focuses on providing precise statistical encodings of anatomy with direct application to a broad range of biological and medical settings. During the past two decades, there has been an ever-increasing pace in the development of neuroimaging techniques, delivering in vivo information on the anatomy and physiological signals of different human organs through a variety of imaging modalities such as MRI, x-ray, CT, and PET. These multi-modality medical images provide valuable data for accurate interpretation and estimation of various biological parameters such as anatomical labels, disease types, cognitive states, functional connectivity between distinct anatomical regions, as well as activation responses to specific stimuli. In the era of big neuroimaging data, Bayes’ theorem provides a powerful tool to deliver statistical conclusions by combining the current information and prior experience. When sufficiently good data is available, Bayes’ theorem can utilize it fully and provide statistical inferences/estimations with the least error rate. Bayes’ theorem arose roughly three hundred years ago and has seen extensive application in many fields of science and technology, including recent neuroimaging, ever since. The last fifteen years have seen a great deal of success in the application of Bayes’ theorem to the field of CA and neuroimaging. That said, given that the power and success of Bayes’ rule largely depends on the validity of its probabilistic inputs, it is still a challenge to perform Bayesian estimation and inference on the typically noisy neuroimaging data of the real world. We assembled contributions focusing on recent developments in CA and neuroimaging through Bayesian estimation and inference, in terms of both methodologies and applications. It is anticipated that the articles in this Research Topic will provide a greater insight into the field of Bayesian imaging analysis.
Download or read book Handbook of Anatomical Models for Radiation Dosimetry written by Xie George Xu and published by CRC Press. This book was released on 2009-09-01 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades, the radiological science community has developed and applied numerous models of the human body for radiation protection, diagnostic imaging, and nuclear medicine therapy. The Handbook of Anatomical Models for Radiation Dosimetry provides a comprehensive review of the development and application of these computational mode
Download or read book Building Computational Atlases from Databases of Whole body Clinical PET written by Vaclav Potesil and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging has revolutionized cancer care and its use has grown massively over the past several decades. Images are increasingly stored in large digital image repositories such as hospital Picture Archiving and Communication System, which will hopefully provide a wealth of information on patient conditions and therapy outcomes as cancer diagnosis and therapy moves from 'one size fits all' to more personalized approaches tailored to each particular patient. However, converting the unstructured avalanche of data at thousands of different hospitals into clinically valuable biomarkers and tools requires that the images of different patients can be compared and efficiently searched. Our research aims to develop novel methods to compare whole-body scans of multiple patients; methods which incorporate 'intelligent' prior knowledge of the internal structure of the human body, as opposed to current methods of image registration which mostly rely on matching the voxel intensities and disregard their anatomical meaning. We develop computational methods for accurate and reliable automated localization of anatomical structures in whole-body images, which will help to automate key steps in cancer diagnosis and radiation treatment planning and save expensive clinicians' time while improving the reliability of their decisions. Conventional approaches to determining spatial correspondences between pairs or sets of images in medical imaging typically rely on image registration methods. There have been considerable advances in registration of multiple images of the same patient taken at different time-points, known as longitudinal studies. However, conventional methods, which rely on optimizing certain integral functions of voxel values over the entire image, are unreliable when applied to aligning whole-body images of different patients. Whole-body Computed Tomography (CT) images contain many different anatomical structures whose physical attributes and consequent appearance can be highly variable between patients. This substantial, but normal, variability is further increased by the presence of pathologies such as tumours and non-cancerous diseases, surgical interventions and degenerative changes due to aging as well as different patterns of contrast agent uptake. Conventional registration methods often get trapped in local minima that abound in such images, resulting in unreliable and inaccurate anatomical correspondences. The methods developed in this thesis tackle the problem of inter-patient registration by incorporating prior anatomical knowledge into parts-based graphical models that accurately and reliably localize arbitrary skeletal and soft-tissue anatomical landmarks in whole-body clinical oncology scans. We optimize parts-based graphical models called Pictorial Structures for accurate and reliable landmark localization in CT images and introduce novel methods that replace standard population models by models personalized to the particular patient. We also propose methods that further improve landmark localization while minimizing, as far as possible, the high costs of ground-truth annotation by expert radiologists. We do this by automatically discovering new landmark correspondences from a database of partially annotated images. The performance of the algorithms developed in my thesis is evaluated on a large database of clinical lung cancer PET/CT scans, showing superior accuracy and reliability of landmark localization compared to conventional methods.
Download or read book Computational Intelligence in Biomedical Imaging written by Kenji Suzuki and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Intelligence in Biomedical Imaging is a comprehensive overview of the state-of-the-art computational intelligence research and technologies in biomedical images with emphasis on biomedical decision making. Biomedical imaging offers useful information on patients’ medical conditions and clues to causes of their symptoms and diseases. Biomedical images, however, provide a large number of images which physicians must interpret. Therefore, computer aids are demanded and become indispensable in physicians’ decision making. This book discusses major technical advancements and research findings in the field of computational intelligence in biomedical imaging, for example, computational intelligence in computer-aided diagnosis for breast cancer, prostate cancer, and brain disease, in lung function analysis, and in radiation therapy. The book examines technologies and studies that have reached the practical level, and those technologies that are becoming available in clinical practices in hospitals rapidly such as computational intelligence in computer-aided diagnosis, biological image analysis, and computer-aided surgery and therapy.
Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2013 written by Kensaku Mori and published by Springer. This book was released on 2013-09-20 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three-volume set LNCS 8149, 8150, and 8151 constitutes the refereed proceedings of the 16th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2013, held in Nagoya, Japan, in September 2013. Based on rigorous peer reviews, the program committee carefully selected 262 revised papers from 789 submissions for presentation in three volumes. The 95 papers included in the first volume have been organized in the following topical sections: physiological modeling and computer-assisted intervention; imaging, reconstruction, and enhancement; registration; machine learning, statistical modeling, and atlases; computer-aided diagnosis and imaging biomarkers; intraoperative guidance and robotics; microscope, optical imaging, and histology; cardiology, vasculatures and tubular structures; brain imaging and basic techniques; diffusion MRI; and brain segmentation and atlases.
Download or read book Abdominal Imaging Computational and Clinical Applications written by Hiroyuki Yoshida and published by Springer. This book was released on 2012-03-06 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the Third International Workshop on Computational and Clinical Applications in Abdominal Imaging, held in conjunction with MICCAI 2011, in Toronto, Canada, on September 18, 2011. The 33 revised full papers presented were carefully reviewed and selected from 40 submissions. The papers are organized in topical sections on virtual colonoscopy and CAD, abdominal intervention, and computational abdominal anatomy.
Download or read book Graphs in Biomedical Image Analysis Computational Anatomy and Imaging Genetics written by M. Jorge Cardoso and published by Springer. This book was released on 2017-09-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed joint proceedings of the First International Workshop on Graphs in Biomedical Image Analysis, GRAIL 2017, the 6th International Workshop on Mathematical Foundations of Computational Anatomy, MFCA 2017, and the Third International Workshop on Imaging Genetics, MICGen 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Québec City, QC, Canada, in September 2017. The 7 full papers presented at GRAIL 2017, the 10 full papers presented at MFCA 2017, and the 5 full papers presented at MICGen 2017 were carefully reviewed and selected. The GRAIL papers cover a wide range of graph based medical image analysis methods and applications, including probabilistic graphical models, neuroimaging using graph representations, machine learning for diagnosis prediction, and shape modeling. The MFCA papers deal with theoretical developments in non-linear image and surface registration in the context of computational anatomy. The MICGen papers cover topics in the field of medical genetics, computational biology and medical imaging.
Download or read book Innovations in Modeling and Simulation to Advance Translational Science written by Melissa Knothe Tate and published by Frontiers Media SA. This book was released on 2020-12-15 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
