Download or read book Compartmental Modeling and Tracer Kinetics written by David H. Anderson and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is concerned with mathematical aspects of compartmental an alysis. In particular, linear models are closely analyzed since they are fully justifiable as an investigative tool in tracer experiments. The objective of the monograph is to bring the reader up to date on some of the current mathematical prob lems of interest in compartmental analysis. This is accomplished by reviewing mathematical developments in the literature, especially over the last 10-15 years, and by presenting some new thoughts and directions for future mathematical research. These notes started as a series of lectures that I gave while visiting with the Division of Applied ~1athematics, Brown University, 1979, and have developed in to this collection of articles aimed at the reader with a beginning graduate level background in mathematics. The text can be used as a self-paced reading course. With this in mind, exercises have been appropriately placed throughout the notes. As an aid in reading the material, the e~d of a proof is indicated by ~. Sub section titles are utilized to make it easier for the reader to skim over detailed material on a first reading and make the entire manuscript somewhat more accessible, especially to nonmathematicians in the biosciences. The preparation of this monograph has been a long task that would not have been completed without the influence of a number of individuals. I am especially indebted to H. T. Banks, J. W. Drane, J. Eisenfe1d, J. A. Jacquez, D. J.
Download or read book Compartmental Modeling and Tracer Kinetics Volume 50 written by DH. Anderson and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tracer Kinetics in Biomedical Research written by Claudio Cobelli and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Introduction. 2. Fundamentals of Tracer Kinetics. 3. The Noncompartmental Model of Multipool Systems. 4. The Compartmental Model. 5. Identifiability of the Tracer Model. 6. Using the Tracer Model to Estimate Kinetic Parameters. 7. Compartmental Versus Noncompartmental Kinetic Parameters. 8. Parameter Estimation: Some Fundamentals of Regression Analysis. 9. Parameter Estimation in Noncompartmental Models. 10. Parameter Estimation in Compartmental Models. 11. Precursor-Product Models. Appendices. Index.
Download or read book Compartmental Analysis in Biology and Medicine written by John Alfred Jacquez and published by . This book was released on 1985 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deals with basic linear and nonlinear systems and graph theory, distribution of tracer-labeled materials, connectivity, and identifiability
Download or read book Tracer Kinetics and Physiologic Modeling written by R.M. Lambrecht and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Compartmental Models and Their Application written by Keith Godfrey and published by . This book was released on 1983 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Kinetic Analysis of Dynamic PET Data written by and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Our goal is to quantify regional physiological processes such as blood flow and metabolism by means of tracer kinetic modeling and positron emission tomography (PET). Compartmental models are one way of characterizing the behavior of tracers in physiological systems. This paper describes a general method of estimating compartmental model rate constants from measurements of the concentration of tracers in blood and tissue, taken at multiple time intervals. A computer program which applies the method is described, and examples are shown for simulated and actual data acquired from the Donner 280-Crystal Positron Tomograph.
Download or read book Splines and Compartment Models written by Karl-Ernst Biebler and published by World Scientific. This book was released on 2013 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents methods of mathematical modeling from two points of view. Splines provide a general approach while compartment models serve as examples for context related to modeling. The preconditions and characteristics of the developed mathematical models as well as the conditions surrounding data collection and model fit are taken into account. The substantial statements of this book are mathematically proven. The results are ready for application with examples and related program codes given. In this book, splines are algebraically developed such that the reader or user can easily understand and vary the numerical construction of the different kinds of spline functions. The classical compartment models of the pharmacokinetics are systematically analyzed and connected with lifetime distributions. As such, parameter estimation and model fit can be treated statistically with a varied minimum chi-square method. This method is applicable for single kinetics and also allows the calculation of average kinetics.
Download or read book Basic Science of PET Imaging written by Magdy M. Khalil and published by Springer. This book was released on 2016-11-07 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Download or read book On line Control and Estimation for Compartmental Models of Tracer Distribution written by Scott Paul McDonald and published by . This book was released on 1978 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Basic Sciences of Nuclear Medicine written by Magdy M. Khalil and published by Springer Nature. This book was released on 2021-05-26 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive and detailed information on the scientific bases of nuclear medicine, addressing a wide variety of topics and explaining the concepts that underlie many of the investigations and procedures performed in the field. The book is divided into six sections that cover the physics and chemistry of nuclear medicine besides associated quality assurance/quality control procedures; dosimetry and radiation biology; SPECT and PET imaging instrumentation plus CT imaging technology in hybrid modalities; data analysis including image processing, reconstruction, radiomics, image degrading correction techniques, along with image quantitation and kinetic modeling. Within these sections, particular attention is paid to recent developments and the advances in knowledge that have taken place since release of the first edition in 2011. Several entirely new chapters have been included and the remaining chapters, thoroughly updated. Innovations in the ever-expanding field of nuclear medicine are predominantly due to integration of the basic sciences with complex technological advances. This excellently illustrated book on the subject will be of interest to not only nuclear medicine physicists and physicians but also clinical scientists, radiologists, radiopharmacists, medical students and technologists.
Download or read book Compartmental Modeling with Networks written by Gilbert G Walter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new advanced text/reference book presents compartmental models or flow models from an applications perspective. Essential topics and methods are introduced in an accessible style with many examples, providing a thorough and comprehensive presentation of compartmental models, model construction and applications.
Download or read book Transpathology written by Mei Tian and published by Elsevier. This book was released on 2024-06-25 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transpathology: Molecular Imaging-Based Pathology is a multidisciplinary reference on molecular imaging and pathology. The book is intended for professionals in the fields of molecular imaging, nuclear medicine, radiology, and pathology as well as students and clinical residents. The book describes the importance of non-invasive diagnosis-based precision medicine and presents a detailed description of current transpathological approaches in different aspects essential for the future development of precision medicine. It’s molecular imaging approach to experimental research and clinical practice will drive the field forward and improve research outcomes. Introduces a new concept of molecular imaging-guided precise biopsy Links in vivo and ex vivo information at various scales by using multi-modality imaging technologies Integrates future technologies for the non-invasive cross-validation of underlying mechanisms
Download or read book Molecular Imaging written by Shankar Vallabhajosula and published by Springer Science & Business Media. This book was released on 2009-07-13 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
Download or read book Information Processing in Medical Imaging written by Nico Karssemeijer and published by Springer. This book was released on 2007-07-14 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 20th International Conference on Information Processing in Medical Imaging, IPMI 2007, held in Kerkrade, The Netherlands, in July 2007. It covers segmentation, cardiovascular imaging, detection and labeling, diffusion tensor imaging, registration, image reconstruction, functional brain imaging, as well as shape models and registration.
Download or read book Encyclopedia of Nonlinear Science written by Alwyn Scott and published by Routledge. This book was released on 2006-05-17 with total page 1107 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 438 alphabetically-arranged essays, this work provides a useful overview of the core mathematical background for nonlinear science, as well as its applications to key problems in ecology and biological systems, chemical reaction-diffusion problems, geophysics, economics, electrical and mechanical oscillations in engineering systems, lasers and nonlinear optics, fluid mechanics and turbulence, and condensed matter physics, among others.
Download or read book Nuclear Cardiac Imaging written by Ami E. Iskandrian and published by Oxford University Press, USA. This book was released on 2015-10-22 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive resource for nuclear cardiologists and nuclear clinicians on the technical, physiological, diagnostic and prognostic considerations of cardiac diagnostic techniques performed with the aid of radiopharmaceuticals.
