Download or read book NAMZARIC Drug Profile 2023 written by DrugPatentWatch and published by DrugPatentWatch.com. This book was released on 2023-08-15 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NAMZARIC Drug Profile, 2023

This report focuses on NAMZARIC and covers the following critical aspects of this drug:

• United States patents
• Expired United States patents
• FDA Paragraph IV patent challenges
• District Court patent litigation
• Patent Trial and Appeal Board (PTAB) patent cases
• European supplementary protection certificates (SPCs)
• Clinical trials
• Drug prices
• Finished product suppliers
• Raw active pharmaceutical ingredient (API) sources

Download or read book NUCYNTA ER Drug Profile 2023 written by DrugPatentWatch and published by DrugPatentWatch.com. This book was released on 2023-08-15 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NUCYNTA ER Drug Profile, 2023

This report focuses on NUCYNTA ER and covers the following critical aspects of this drug:

• United States patents
• Expired United States patents
• FDA Paragraph IV patent challenges
• District Court patent litigation
• Patent Trial and Appeal Board (PTAB) patent cases
• European supplementary protection certificates (SPCs)
• Clinical trials
• Drug prices
• Finished product suppliers
• Raw active pharmaceutical ingredient (API) sources

Download or read book The Hard Sell written by Evan Hughes and published by Doubleday. This book was released on 2022-01-18 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inside story of a band of entrepreneurial upstarts who made millions selling painkillers—until their scheme unraveled, putting them at the center of a landmark criminal trial. • SOON TO BE THE MAJOR MOTION PICTURE PAIN HUSTLERS STARRING EMILY BLUNT AND CHRIS EVANS "Unfolds with the velocity and verve of a Scorsese film…A tour de force."—Patrick Radden Keefe, New York Times bestselling author of Empire of Pain and Say Nothing John Kapoor had already amassed a small fortune in pharmaceuticals when he founded Insys Therapeutics. It was the early 2000s, a boom time for painkillers, and he developed a novel formulation of fentanyl, the most potent opioid on the market. Kapoor, a brilliant immigrant scientist with relentless business instincts, was eager to make the most of his innovation. He gathered around him an ambitious group of young lieutenants. His head of sales—an unstable and unmanageable leader, but a genius of persuasion—built a team willing to pull every lever to close a sale, going so far as to recruit an exotic dancer ready to scrape her way up. They zeroed in on the eccentric and suspect doctors receptive to their methods. Employees at headquarters did their part by deceiving insurance companies. The drug was a niche product, approved only for cancer patients in dire condition, but the company’s leadership pushed it more widely, and together they turned Insys into a Wall Street sensation. But several insiders reached their breaking point and blew the whistle. They sparked a sprawling investigation that would lead to a dramatic courtroom battle, breaking new ground in the government’s fight to hold the drug industry accountable in the spread of addictive opioids. In The Hard Sell, National Magazine Award–finalist Evan Hughes lays bare the pharma playbook. He draws on unprecedented access to insiders of the Insys saga, from top executives to foot soldiers, from the patients and staff of far-flung clinics to the Boston investigators who treated the case as a drug-trafficking conspiracy, flipping cooperators and closing in on the key players. With colorful characters and true suspense, The Hard Sell offers a bracing look not just at Insys, but at how opioids are sold at the point they first enter the national bloodstream—in the doctor’s office.

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Download or read book LexisNexis Corporate Affiliations written by and published by . This book was released on 2004 with total page 2412 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Corporation in the Twenty First Century written by John Kay and published by Profile Books. This book was released on 2024-08-22 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: SHORTLISTED FOR THE FINANCIAL TIMES AND SCHRODERS BUSINESS BOOK OF THE YEAR 2024 "Original and thought-provoking... A brilliantly erudite account of the major waves in the theory and practice of management" - The Financial Times "The doyen of British thinkers on the evolution of business...One of the great attractions of his [work] is that he stands above and apart from conventional political attitudes" - Literary Review For generations, we have defined a corporation as a business run by a capitalist elite, that uses its accumulated wealth to own the means of production and exercise economic power. That is no longer the reality. In the twenty-first century, our most desired goods and services aren't stacked in warehouses or on container ships: they appear on your screen, fit in your pocket or occupy your head. But even as we consume more than ever before, big business faces a crisis of legitimacy. The pharmaceutical industry creates life-saving vaccines but has lost the trust of the public. The widening pay gap between executives and employees is destabilising our societies. Facebook and Google have more customers than any companies in history but are widely reviled. John Kay, one of the greatest economists of our time, describes how the pursuit of shareholder value has destroyed some of the leading companies of the twentieth century. Incisive and provocative, this book redefines successful commercial activity and leadership, the knowledge economy and what the future of the modern corporation might be.

Download or read book New Tools to Interrogate Endocannabinoid Signalling written by Mauro Maccarrone and published by Royal Society of Chemistry. This book was released on 2020-11-06 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legalization of cannabis extracts around the world has led to a resurgence of interest into research surrounding endocannabinoids (eCBs) and the endocannabinoid system. This system is formed of a complex array of receptors, metabolic enzymes and transporters that finely tune the manifold biological activities of eCBs and there is an urgent need for the development of selective drugs to dissect the contribution of eCBs to the aetiology of various diseases. New Tools to Interrogate Endocannabinoid Signalling comprehensively covers the innovative research into both natural and synthetic compounds that affect this pathway and taking a target-based approach, assesses their potential for therapeutic use. With contributions from global leaders in the field, this timely volume will be a valuable resource to pharmaceutical researchers and medicinal chemists working in natural products and endocannabinoid drug discovery in academia and industry.

Download or read book Nelson s Directory of Investment Research written by and published by . This book was released on 2008 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Karch s Drug Abuse Handbook written by Steven Karch and published by CRC Press. This book was released on 2022-11-29 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt: Karch’s Drug Abuse Handbook, Third Edition remains the quintessential compendium addressing the pharmacological, medical, and legal aspects of drugs and informing the forensic community of the latest scientific advances and emergent practices. For this edition, Dr. Karch has brought on clinical and forensic toxicology expert Dr. Bruce Goldberger, editor-in-chief of the Journal of Analytical Toxicology and president of the American Board of Forensic Toxicology, to serve as co-editor. In addition, world-renowned scientists and medical professionals have contributed their work and expertise in tackling the latest developments in drug testing, drug-related medical emergencies, and the drug toxicology. Topics addressed include genetic testing in drug death investigation, pathology, toxicogenetics, alcohol, post-mortem toxicology, new psychoactive substances, the latest legal issues and challenges as well as drugs and drug testing in sports, and the ethical, legal, and practical issues involved. Vivid pictures and diagrams throughout illustrate the pathological effects of drugs and the chemical make-up and breakdown of abused drugs. With unparalleled detail, the latest research and the highest level of authoritative medical scientific information, The Drug Abuse Handbook, Third Edition remains the definitive resource for drug related issues.

Download or read book Schacht V Brown written by and published by . This book was released on 1983 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Excipient Applications in Formulation Design and Drug Delivery written by Ajit S Narang and published by Springer. This book was released on 2015-10-07 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated characterization of excipients and in-depth understanding of their roles in drug delivery applications. This book presents a concise summary of relevant scientific and mechanistic information that can aid the use of excipients in formulation design and drug delivery applications. Each chapter is contributed by chosen experts in their respective fields, which affords truly in-depth perspective into a spectrum of excipient-focused topics. This book captures current subjects of interest – with the most up to date research updates – in the field of pharmaceutical excipients. This includes areas of interest to the biopharmaceutical industry users, students, educators, excipient manufacturers, and regulatory bodies alike.

Download or read book Supportive Care in Cancer Patients written by Hans-Jörg Senn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: The symposium on supportive care in cancer patients, which took place in St. Gallen, Switzerland, on February 18-21, 1987, wel comed renowned experts in the field and more than 600 partici pants from 25 countries with the aim of stimulating discussion on how to improve our professional skills and personal attitudes to ward cancer patients in all stages of their disease. Why did we or ganize such a symposium on supportive care in cancer patients? Recent decades have witnessed remarkable success in cancer treat ment, and we have learned how to cure a finite number of neoplas tic diseases. Some malignant tumors that previously entailed high fatality rates, such as leukemias, lymphomas, and testicular can cers, can now be cured, even when at an advanced stage. Yet it seems to many that our struggle to improve results and to fight death from cancer has also imposed greater toxicity on patients. Conventional scientifically based oncology has only recently made adequate efforts to improve the subjective quality of life of cancer patients, for example through prophylaxis against emesis, nausea, and scalp hypothermia, pain control and the development of psy chosocial support structures. The search for less toxic and yet equally effective treatment measures has not been one of our pri mary goals in the past. Supportive care has always been part of nurses' professional aim, even though many have not known how best to offer it.

Download or read book Nelson Information s Directory of Investment Research written by and published by . This book was released on 2008 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Treatment of Chronic Pain by Interventional Approaches written by Timothy R. Deer and published by Springer. This book was released on 2014-12-08 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: From reviews of Deer, eds., Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches: "Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches is a major textbook... [I]t should be a part of all departmental libraries and in the reference collection of pain fellows and pain practitioners. In fact, this text could be to pain as Miller is to general anesthesia." Journal of Neurosurgical Anesthesiology Edited by master clinician-experts appointed by the American Academy of Pain Medicine, this is a soft cover version of the Interventional sections of the acclaimed Deer, eds., Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches. It is intended as a primary reference for busy clinicians who seek up-to-date and authoritative information about interventional approaches to treating chronic pain. State-of-the-art coverage of full range of techniques: neural blockades, neurolysis blocks, and neurostimulation Review of clinically relevant anatomy and physiology "Key Points" preview contents of each chapter

Download or read book Brain Tumor Imaging written by Elke Hattingen and published by Springer. This book was released on 2015-09-02 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.

Download or read book Handbook of Methadone Prescribing and Buprenorphine Therapy written by Ricardo A. Cruciani and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methadone and buprenorphine are the only two opioids that are indicated for the management of both pain and opioid-related drug addiction. Both present unique challenges to the general practitioner and pain specialist, requiring a separate analysis from the rest of the drugs in the same family. Handbook of Methadone Prescribing and Buprenorphine Therapy is an invaluable guide to the safe use of these opioids. Authored by clinical and academic leaders from a variety of settings and backgrounds, this book includes chapters on pharmacology, adverse effects, safe rotation from other opioids, cardiac toxicity, prescribing, pharmacokinetics, equianalgesic dose and replacement therapy. This comprehensive text provides clinicians, researchers, policy-makers and academicians a resource for all the relevant points in methadone prescribing and buprenorphine therapy.

Download or read book WHO Expert Committee on Drug Dependence written by World Health Organization and published by World Health Organization. This book was released on 2024-04-19 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Forty-sixth Meeting of the World Health Organisation (WHO)’s Expert Committee on Drug Dependence (ECDD) was convened from 16 to 19 October 2023 and was coordinated from the WHO headquarters in Geneva. The Forty-sixth WHO ECDD critically reviewed six new psychoactive substances: including two benzodiazepines (bromazolam, flubromazepam), one novel synthetic opioid (butonitazene), two cathinones/stimulants (3-CMC, dipentylone) and one dissociative-type substance (2-fluorodeschloroketamine). A critical review to consider international scheduling measures was undertaken for each substance so that the Expert Committee could consider whether information about these substances may justify the scheduling or a change in scheduling of a substance in the 1961 or 1971 Conventions. In addition, the Forty-sixth ECDD carried out a pre-review of nitrous oxide and carisoprodol to consider whether current information justified a critical review. This report summarizes the findings of the forty-sixth ECDD meeting.