Download or read book Collagen Biomaterials for Wound Treatment Development written by S. Udhayakumar and published by Independent Author. This book was released on 2023-07-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collagen biomaterials have gained significant attention in the development of wound treatments due to their similarity to the extracellular matrix (ECM) in the human body. Bovine tissue has emerged as an unexplored source of collagen biomaterials, and studies have shown promising results in their effectiveness for wound healing. This article by S. Udhayakumar focuses on the development of collagen biomaterials from bovine tissue for wound treatment and their in vitro, in vivo, and clinical validation. The extracellular matrix is a complex network of proteins and other molecules that provide structural and biochemical support to cells. Collagen, the most abundant protein in the ECM, is responsible for providing tensile strength and structural support. In wound healing, the ECM plays a crucial role in regulating cell behavior and signaling, and collagen biomaterials mimic the natural ECM, making them ideal for wound treatment. The development of collagen biomaterials involves the extraction of collagen from bovine tissue and processing it into various forms, such as scaffolds, hydrogels, matrices, fibers, peptides, and fibrils. These biomaterials can be used for wound closure devices, wound dressings, and wound closure systems. The biomaterials are designed to promote wound healing by facilitating angiogenesis, cell migration, and inflammation reduction while preventing scar formation. In vitro studies have shown that collagen biomaterials support the growth and function of fibroblasts and keratinocytes, two essential cell types in wound healing. These studies have also demonstrated that collagen biomaterials support wound closure time and promote wound bed preparation. In vivo studies in animal models have shown that collagen biomaterials promote wound closure, and they are safe and effective for use in wound healing. Clinical trials have also demonstrated the effectiveness of collagen biomaterials in treating chronic wounds, acute wounds, burn wounds, diabetic foot ulcers, pressure ulcers, and surgical wounds. Collagen biomaterials' success is due to their similarity to the human ECM, which makes them highly biocompatible and biodegradable, making them ideal for use in tissue engineering and regenerative medicine. Collagen biomaterials can also be used for environmental remediation, sustainable agriculture, and waste management. In conclusion, collagen biomaterials derived from bovine tissue have significant potential in wound treatment development. Their in vitro, in vivo, and clinical validation shows that they are highly effective for wound closure and safe for use. Collagen biomaterials are sustainable, eco-friendly, and highly adaptable for different wound types and wound management strategies.

Download or read book Advanced Wound Repair Therapies written by David Farrar and published by Elsevier. This book was released on 2011-06-21 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds.Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices.With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject. - Provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds - Chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing - Covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair

Download or read book Wound Healing Biomaterials Volume 2 written by Magnus Ågren and published by Woodhead Publishing. This book was released on 2016-05-30 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care. - Includes more systematic and comprehensive coverage on the topic of wound care - Provides thorough coverage of all specific therapies and biomaterials for wound healing - Contains clear layout and organization that is carefully arranged with clear titles and comprehensive section headings - Details specific sections on the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and more

Download or read book Therapeutic Dressings and Wound Healing Applications written by Joshua Boateng and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest research on techniques for effective healing of chronic and difficult to heal wounds The healing of chronic wounds is a global medical concern, specifically for patients suffering from obesity and type II diabetes. Therapeutic Dressing and Wound Healing Applications is an essential text for research labs, industry professionals, and general clinical practitioners that want to make the shift towards advanced therapeutic dressing and groundbreaking wound application for better healing. This book takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: ● Debridement and disinfection properties of wound dressing ● Biofilms, silver nanoparticles, and honey dressings ● Clinical perspectives for treating diabetic wounds ● Treating mixed infections ● Wound healing and tissue regeneration treatments ● Gene based therapy, 3D bioprinting and freeze-dried wafers Anyone looking to update and improve the treatment of chronic wounds for patients will find the latest pertinent information in Therapeutic Dressing and Wound Healing Applications.

Download or read book Bioengineering In Wound Healing A Systems Approach written by Martin L Yarmush and published by World Scientific. This book was released on 2017-03-24 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is a wound, how does it heal, and how can we prevent scarring? The concept of wound healing has puzzled humans even before the advent of modern medicine.In recent years, bioengineering has tackled the problems of cancer, tissue engineering and molecular manufacturing. The broad spectrum of technologies developed in these fields could potentially transform the wound care practice. However, entering the world of wound healing research is challenging — a broad spectrum of knowledge is required to understand wounds and improve healing.This book provides an essential introduction of the field of wound healing to bioengineers and scientists outside the field of medicine. Written by leading researchers from various fields, this book is a comprehensive primer that gives readers a holistic understanding of the field of wound biology, diagnostics and treatment technologies.

Download or read book Wound Healing Biomaterials Volume 1 written by Magnus Ågren and published by Woodhead Publishing. This book was released on 2016-06-03 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials. - Provides more systematic and comprehensive coverage of specific therapies and biomaterials for wound healing - Highlights research that is concerned with new therapies, regeneration methods, and the use of biomaterials to assist in wound healing and healing response - Presents an organized layout of the material that is carefully arranged with clear titles and comprehensive section headings - Looks at tissue regeneration strategies, making this an all encompassing book on the topic of wound care

Download or read book Biomaterials for Treating Skin Loss written by D P Orgill and published by Elsevier. This book was released on 2009-01-28 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary causes of wounds requiring skin replacement are severe burns and ulcers. Materials must provide an effective temporary barrier, promote healing and minimise scarring. Massive improvements have been made to skin repair biomaterials in the last ten years with widespread adoption of new developments in the medical sector. This book provides a comprehensive review of the range of biomaterials for treating skin loss. Part one discusses the basics of skin replacement with chapters on such topics as markets and regulation, biomechanics and the biological environment of skin. Part two then reviews epidermal and dermal replacement technology with chapters on such topics as alternative delivery of keratinocytes, collagen-based and human origin-based dermal replacement, and lyophilized xenogenic products. The final section explores combined dermis and epidermal replacement technologies and provides a round-up of skin replacement principles. With its distinguished editors and international team of contributors, Biomaterials for treating skin loss is a standard reference for those researching skin replacement technologies, particularly those interested in treating burns and ulcers. Comprehensively reviews the range of biomaterials for treating skin loss and skin replacement principles Examines the basis of skin loss from products and markets through to regulation and the biological environment of skin Highlights developments in epidermal and dermal replacement technology covering topics such as collagen-based and human origin-based dermal replacement

Download or read book Bioactive Polysaccharide Materials for Modern Wound Healing written by Tina Maver and published by Springer. This book was released on 2018-04-23 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first concise book that includes different aspects of naturally-derived components for wound healing. It presents the first exhaustive review of modern techniques in wound dressing development. With a growing, ageing population and the rapid growth of the wound-care market, the authors explore the current trend of bio-based products (active components and host materials) in this field. After a short introduction into modern solutions in wound-care and modern techniques in wound-dressing development, the authors, leaders in the field, explore natural-based components (drugs, extracts, materials etc.); safety and efficiency assessments (biocompatibility, cytotoxicity and in vitro performance etc.); and model films as a platform for the development of new wound dressings.

Download or read book Natural Polymers in Wound Healing and Repair written by Mahesh K. Sah and published by Elsevier. This book was released on 2022-06-23 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Polymers in Wound Healing and Repair: From Basic Concepts to Emerging Trends presents comprehensive coverage on the development and application of natural polymers in wound healing and repair, including fundamental concepts, traditional approaches, cutting-edge methods and emerging trends. The application of natural polymers has evolved from their use in the simplest wound management material, to drug eluting matrices, to cell-laden constructs, and to 3D bio-printed skin equivalents. This book reflects the remarkable progress that has been made in recent years in this innovative field. This is an essential resource for researchers, scientists, and advanced students across polymer science, biomaterials, bio-based and sustainable materials, biomedicine, biomedical engineering, pharmaceuticals, and materials science and engineering. It will also be valuable to R&D professionals, scientists, technologists and all those working in a medical setting who are interested in the latest developments in advanced materials for wound management, healing and repair. - Provides up-to-date coverage of natural polymer-based biomaterials in wound healing and repair, covering sources, processing and properties - Describes cellular and molecular events in wound healing - Introduces conventional and advanced methodologies for wound management - Offers a comprehensive understanding of state-of-the-art and emerging concepts in wound healing, including drug-eluting matrices, cell-laden systems and personalized bio-fabrication strategies

Download or read book Nanoparticle Based Collagen Biomaterials for Wound Healing written by Nirmal Mazumder and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wounds and infections are extremely common cases that are dealt with in the medical field. Their effective and timely treatment ensures the overall well-being of patients in general. Current treatments include the use of collagen scaffolds and other biomaterials for tissue regeneration. Although the use of collagenous biomaterials has been tested, the incorporation of nanoparticles into these collagenous biomaterials is a fairly new field, whose possibilities are yet to be explored and discovered. The current chapter explores the applications of the amalgamation of collagenous biomaterials with nanoparticles, which themselves are known to be effective in the treatment and prevention of infections.

Download or read book Advances in Wound Healing Materials written by Willi Paul and published by Smithers Rapra. This book was released on 2015-06-11 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wound healing and wound care technologies are an ever expanding field with the advancement of materials science, biomedicine and tissue engineering. In the year 2011 the global wound care market generated US$ 6,500 million with an annual growth rate of 7.5%. The global advanced wound care products market share in 2023 is predicted to be approximately US$ 16,300 million.This book discusses the evolution of wound care devices and protocol over the years and different technologies being used in the present day wound care treatment. New strategies involving engineered tissues and drug delivery to mimic the natural wound healing milieu are discussed. The use of cytokine growth factors enhances chronic wound healing particularly for burn wound healing. Prevention of scarring, keloid formation or contractures and a cosmetically acceptable healing is a challenge even now.Skin tissue engineering was the first successfully clinically applied product in regenerative medicine. Bioengineered skin seeded with fibroblast and keratinocyte cells could form a permanent solution that do not require skin grafting or as a temporary cover for burns prior to grafting. Cell attachment, proliferation and tissue formation in a three-dimensional porous scaffold can be engineered for specific application. These cell based skin substitutes had significant wound healing and scar reducing effect on patients.Gene-activated dermal equivalent is another emerging approach for the healing of full thickness incision wounds with good remodelling of the skin. The book also describes similar latest developments on wound healing science and research.The target audiences are wound care professionals, researchers working on wound healing technology and skin tissue engineering; as well as graduate students and industries that need to understand the aspects of wound healing and technological orientation towards successful commercialisation.

Download or read book Development of Acoustically Modified Collagen Based Biomaterials for Regenerative Medicine Applications written by Emma Grygotis Norris and published by . This book was released on 2019 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic wounds are a major public health burden affecting 6.5 million adults in the United States alone, with healthcare costs upwards of $25 billion annually. Regenerative medicine approaches, including the use of tissue-engineered biomaterials, are a promising strategy to reinitiate healing in these patients. Engineered biomaterials rely on scaffolding structures, often extracellular matrix (ECM) glycoproteins, to provide structural support and biological cues. Of these, type I collagen has proved a valuable starting material due to its ability to self-assemble into 3D structures in vitro, as well its high abundance in a variety of tissues including the skin. Collagen achieves this versatility through a cell-mediated hierarchical assembly process that imparts tissue-specific characteristics including collagen fibril conformation, organization and interactions with other ECM components such as fibronectin. Therefore, strategies to control collagen structure and organization in vitro will facilitate development of improved biomaterials that can direct the behavior of cells within engineered constructs. The work reported in this thesis developed an ultrasound (US) technique to manipulate the structure and function of collagen within 3D hydrogels. US exposure during hydrogel polymerization produced localized changes in collagen and fibronectin fiber organization via both thermal and non-thermal acoustic mechanisms. Acoustically-modified hydrogels in turn modified cellular behaviors essential to wound healing, including adhesion, migration, ECM remodeling, and cellular self-assembly. Together, these studies demonstrate that ultrasound can be used to modify the structure and function of ECM-based biomaterials both site-specifically and non-invasively. These findings suggest that therapeutic ultrasound will be a promising addition to the expanding toolbox of strategies to design therapeutic materials of greater complexity and biological compatibility.

Download or read book Wound Healing written by Ana Colette Maurício and published by BoD – Books on Demand. This book was released on 2023-06-14 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skin wounds are common occurrences that result from the breakdown of anatomical continuity and integrity of the epidermis, with consequent functional changes. Wound healing is a complex phenomenon through which there is healing of the skin. The wound healing process begins immediately after the wound occurs and can be a lengthy and complex process depending on the severity of the wound and the normal or abnormal healing progress. Wound healing progress through three distinct phases of inflammation, proliferation, and remodeling in a methodical and complex sequence that involves cellular, molecular, and humoral mechanisms of action. Any change in this sequence of events can lead to abnormal wound healing. Due to the health and psychological consequences of wounds that are difficult to heal there has been a continuous effort to develop new therapies that promote wound healing more quickly and effectively and that restore the skin’s barrier function. Nevertheless, this situation remains a medical challenge. This book presents some therapeutic advances based on new and innovative therapeutic options, medical devices, and biomaterials to promote wound healing. It is a theoretical and practical reference for future research on chronic wound healing.

Download or read book Wound Closure Biomaterials and Devices written by Chih-Chang Chu and published by CRC Press. This book was released on 2018-05-04 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï

Download or read book Collagen from Tissue Culture to Biomaterials Tissue Engineering and Beyond written by Elena García-Gareta and published by Cambridge Scholars Publishing. This book was released on 2019-01-21 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: As collagen is the main structural component of body tissues, there has been much effort expended, both in the past and today, to use it in cell culture applications. Indeed, its importance is further stressed by the wide use of collagen biomaterials in tissue repair and regeneration, including the treatment of burns, chronic wounds or bone repair. This book represents a journey through recent scientific history, and describes the massive implications of the research carried out by Bornstein, Ehrmann and Gey on collagen preparations in the 1950s for cell culture and more recently, tissue engineering and personalised medicine.

Download or read book Product Guide to Skin Wound Care written by Cathy Hess and published by Lippincott Williams & Wilkins. This book was released on 2019-11-04 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Choose the best possible skin and wound care products to support your patients’ skin health and wound healing, with the invaluable Product Guide to Skin and Wound Care, 8th Edition. Listing 294 products in alphabetical order, this handy product guide for wound care practitioners across all practice settings offers detailed information—sizes, action, indications, contraindications, application, and removal information—so that your choices stay informed and accurate.

Download or read book Advanced Textiles for Wound Care written by S. Rajendran and published by Elsevier. This book was released on 2009-04-30 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important and growing area of the textile industry is the medical sector. The extent of this growth is due to constant improvements in both textile technology and medical procedures. This collection provides a detailed review of how textiles are incorporated into wound care applications, explaining the importance and suitability of using textiles on different wound types.Part one of the book provides an overview of the use of textiles in particular aspects of wound care, providing details of wound management and the importance of laboratory testing in relation to wound care. Further chapters cover minor wounds, moist wound management and bioactive dressings to promote healing. Given their increasing importance, part two describes how advanced textiles, such as smart temperature controlled textiles and composites, can be used for wound care products. The final chapter gives an interesting insight into the use of fibrous scaffolds for tissue engineering.Advanced textiles for wound care is essential reading for any manufacturers, designers, scientists and producers of wound care materials. It is a valuable resource for professionals within the medical sector, as well as those in academia. - Provides a comprehensive introduction to wound care from types of wound and wound healing mechanisms to the importance of testing in relation to wound care - Analyses the application of textiles to wound healing covering minor wounds, burns, ulcers and other deep skin wounds - Reviews the current use of smart textiles for wound care including drug delivery dressings and textile-based scaffolds for tissue engineering as well as future trends