Download or read book Coalescent written by Stephen Baxter and published by Del Rey. This book was released on 2003-11-18 with total page 759 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Lean, taut storytelling . . . breakneck stuff . . . Arguably his most accessible book to date—Baxter [is] resplendent.”—SFX magazine When his father dies suddenly, George Poole stumbles onto a family secret: He has a twin sister he never knew existed, who was raised by an enigmatic cult called the Order. The Order is a hive—a human hive with a dominant queen—that has prospered below the streets of Rome for almost two millennia. After Poole enters the Order’s vast underground city and meets the disturbing inhabitants, he uncovers evidence that they have embarked on a divergent evolutionary path. These genetically superior humans are equipped with the tools necessary to render modern Homo sapiens as extinct as the Neanderthals. And now they are preparing to leave their underground realm. “[Excels] at both action-packed storytelling and philosophical speculation.”—Library Journal “Utterly fascinating . . . constantly surprising . . . Coalescent reveals a new side to Baxter’s vast talent.”—Locus

Download or read book Coalescent Theory written by John Wakely and published by Roberts. This book was released on 2016-04-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides the foundation for molecular population genetics and genomics. It shows the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data.

Download or read book Coalescent Argumentation written by Michael A. Gilbert and published by Routledge. This book was released on 2013-11-05 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coalescent Argumentation is based on the concept that arguments can function from agreement, rather than disagreement. To prove this idea, Gilbert first discusses how several components--emotional, visceral (physical) and kisceral (intuitive) are utilized in an argumentative setting by people everyday. These components, also characterized as "modes," are vital to argumentative communication because they affect both the argument and the resulting outcome. In addition to the components/modes, this book also stresses the goals in argumentation as a means for understanding one's own and one's opposer's positions. Gilbert argues that by viewing positions as complex human events involving a variety of communicative modes, we are better able to find commonalities across positions, and, therefore, move from conflict to resolution. By focusing on agreement and shared goals in all modes, arguers can coalesce diverse positions and more easily distinguish between minor or unrelated differences and core disagreements. This permits much greater latitude for locating shared beliefs, values, and attitudes that will lead to conflict resolution.

Download or read book Gene Genealogies Variation and Evolution A primer in coalescent theory written by Jotun Hein and published by Oxford University Press, USA. This book was released on 2004-12-09 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;Coalescent theory is a central concept in the study of genetic sequence variation that probabilistically describes the genealogy relating the sampled sequences. In this text, besides fulfilling the glaring need for such a book, the authors present this theory in a straightforward and elementary manner and describe the statistical and computational methods used in modelling and analyzing genetic sequence variation. Rich in examples and illustrations the book covers basic concepts, complications arising from geographical structure and recombination before considering aspects of statistical inference based on these models. The book ends with chapters on Gene Mapping, which combines sequence variation data with phenotypic data (such as disease) to define areas of the genome where genes are responsible for the trait, and Human Evolution, a research area that is experiencing a renaissance due to the enormous amounts of data produced in molecular studies. Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. It is highly suitable for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine and students studying the evolution of human population and disease, and will be an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;an excellent and timely book that should appeal to a variety of people in genetics and applied mathematics. - Professor Montgomery Slatkin (Berkeley);the authors are outstanding experts in the field, and the book is topical and timely. - Professor David Balding (Imperial College);Hein, Schierup and Wiuf have written the first general book on the coalescent. It is an engaging combination of clear mathematical derivation and real data examples. - Professor Joe Felsenstein (University of Washington)

Download or read book Handbook of Statistical Genomics written by David J. Balding and published by John Wiley & Sons. This book was released on 2019-07-09 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Download or read book Chiefdoms Collapse and Coalescence in the Early American South written by Robin Beck and published by Cambridge University Press. This book was released on 2013-06-24 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a new framework for understanding the transformation of the Native American South during the first centuries of the colonial era.

Download or read book Exultant written by Stephen Baxter and published by Del Rey. This book was released on 2004-10-26 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Baxter has an uncanny gift for mixing a punchy, cyberpunk cynicism with his resolutely hard SF story base. . . . [Exultant] rivals Asimov in its boundless vision for the future evolution of humanity.”—Kirkus Reviews (starred review) For more than twenty thousand years, humans have been at war with the alien race of Xeelee. Faced with certain death, a young pilot, Pirius, disobeys orders and travels into the future. Upon his return, Pirius is court-martialed and sentenced to penal servitude. But it is not only Pirius who pays the price. In flying into the future and back again, Pirius returned to a time before he’d left, a time inhabited by his younger self, who also receives punishment. Commissary Nilis believes that the elder Pirius, whom he dubs Pirius Blue, may know how to defeat the Xeelee. But Nilis can do nothing for Pirius Blue. Instead, he takes the younger Pirius—Pirius Red—back to Earth. There Pirius Red will discover truths that shatter his preconceived notions of all that he is fighting for, while Pirius Blue will learn even harsher truths. But the most shocking revelation of all is still to come. “Absurdly ambitious, technically brilliant, and downright exciting.”—SFX Magazine “Striking . . . chilling . . . [with] a triumphant conclusion.”—Starburst

Download or read book Statistical Population Genomics written by Julien Y Dutheil and published by . This book was released on 2020-10-08 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Download or read book Transcendent written by Stephen Baxter and published by Del Rey. This book was released on 2005-11-29 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Breathtaking . . . brilliantly conducted . . . Far-future philosophic space opera and near-future eco-thriller combine effectively.”—Locus It is the year 2047, and nuclear engineer Michael Poole is mourning the death of his beloved wife and doubting his own sanity. But he must stave off a looming catastrophe: vast reservoirs of toxic gases lie beneath the melting poles, threatening to contaminate the atmosphere and destroy all life on Earth. Though born five hundred thousand years after the death of Michael Poole, Alia knows him intimately. Every person in Alia’s world is entrusted with Witnessing one life from the past by means of a technology able to traverse time. Alia’s subject is Michael Poole. Chosen to become a Transcendent, a member of the group mind that is shepherding humanity toward an evolutionary apotheosis, Alia discovers a dark side to the Transcendent’s plans. Somehow, Michael holds the fate of the future in his hands, and to save that future, Alia must undertake a desperate journey into the past. “Stunning . . . engaging . . . a contrasting mix of Baxter’s customary skill at presenting a very realnear future, and his talent for high-level hardscience fiction.”—Starburst

Download or read book How to Suppress Women s Writing written by Joanna Russ and published by University of Texas Press. This book was released on 1983-09 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses the obstacles women have had to overcome in order to become writers, and identifies the sexist rationalizations used to trivialize their contributions

Download or read book Combinatorial Stochastic Processes written by Jim Pitman and published by Springer Science & Business Media. This book was released on 2006-05-11 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this text is to bring graduate students specializing in probability theory to current research topics at the interface of combinatorics and stochastic processes. There is particular focus on the theory of random combinatorial structures such as partitions, permutations, trees, forests, and mappings, and connections between the asymptotic theory of enumeration of such structures and the theory of stochastic processes like Brownian motion and Poisson processes.

Download or read book Harmony of Gr bner Bases and the Modern Industrial Society written by Takayuki Hibi and published by World Scientific. This book was released on 2012 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume consists of research papers and expository survey articles presented by the invited speakers of the conference on OC Harmony of GrAbner Bases and the Modern Industrial SocietyOCO. Topics include computational commutative algebra, algebraic statistics, algorithms of D-modules and combinatorics. This volume also provides current trends on GrAbner bases and will stimulate further development of many research areas surrounding GrAbner bases."

Download or read book Branching Processes written by Patsy Haccou and published by Cambridge University Press. This book was released on 2005-05-19 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the mathematical idea of branching processes, and tailors it for a biological audience.

Download or read book Population Genetics written by Matthew B. Hamilton and published by John Wiley & Sons. This book was released on 2021-02-10 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now updated for its second edition, Population Genetics is the classic, accessible introduction to the concepts of population genetics. Combining traditional conceptual approaches with classical hypotheses and debates, the book equips students to understand a wide array of empirical studies that are based on the first principles of population genetics. Featuring a highly accessible introduction to coalescent theory, as well as covering the major conceptual advances in population genetics of the last two decades, the second edition now also includes end of chapter problem sets and revised coverage of recombination in the coalescent model, metapopulation extinction and recolonization, and the fixation index.

Download or read book Human Population Genetics written by John H. Relethford and published by John Wiley & Sons. This book was released on 2012-02-15 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introductory guide to human population genetics and microevolutionary theory Providing an introduction to mathematical population genetics, Human Population Genetics gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study. Thorough and accessible, Human Population Genetics presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory. Human Population Genetics includes: Helpful formulae for learning ease Graphs and analogies that make basic points and relate the evolutionary process to mathematical ideas Glossary terms marked in boldface within the book the first time they appear In-text citations that act as reference points for further research Exemplary case studies Topics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow Human Population Genetics solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study. NOTE: errata for the first edition can be found at the author's website: http://employees.oneonta.edu/relethjh/HPG/errata.pdf

Download or read book Bioinformatics written by Mahmood A. Mahdavi and published by BoD – Books on Demand. This book was released on 2011-11-02 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics - Trends and Methodologies is a collection of different views on most recent topics and basic concepts in bioinformatics. This book suits young researchers who seek basic fundamentals of bioinformatic skills such as data mining, data integration, sequence analysis and gene expression analysis as well as scientists who are interested in current research in computational biology and bioinformatics including next generation sequencing, transcriptional analysis and drug design. Because of the rapid development of new technologies in molecular biology, new bioinformatic techniques emerge accordingly to keep the pace of in silico development of life science. This book focuses partly on such new techniques and their applications in biomedical science. These techniques maybe useful in identification of some diseases and cellular disorders and narrow down the number of experiments required for medical diagnostic.

Download or read book Eclectic Short hand Writing by Principles Instead of Arbitrary Signs written by Jesse George Cross and published by . This book was released on 1888 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: