Download or read book Knowledge Based Bioinformatics written by Gil Alterovitz and published by John Wiley & Sons. This book was released on 2011-04-20 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an increasing need throughout the biomedical sciences for a greater understanding of knowledge-based systems and their application to genomic and proteomic research. This book discusses knowledge-based and statistical approaches, along with applications in bioinformatics and systems biology. The text emphasizes the integration of different methods for analysing and interpreting biomedical data. This, in turn, can lead to breakthrough biomolecular discoveries, with applications in personalized medicine. Key Features: Explores the fundamentals and applications of knowledge-based and statistical approaches in bioinformatics and systems biology. Helps readers to interpret genomic, proteomic, and metabolomic data in understanding complex biological molecules and their interactions. Provides useful guidance on dealing with large datasets in knowledge bases, a common issue in bioinformatics. Written by leading international experts in this field. Students, researchers, and industry professionals with a background in biomedical sciences, mathematics, statistics, or computer science will benefit from this book. It will also be useful for readers worldwide who want to master the application of bioinformatics to real-world situations and understand biological problems that motivate algorithms.

Download or read book Kaufman s Atlas of Mouse Development Supplement written by Richard Baldock and published by Academic Press. This book was released on 2015-09-23 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. - Provides high-resolution images for best visualization of key developmental processes and structures - Offers in-depth anatomy and morphological views of organ systems - Written descriptions convey developmental origins of the organ systems

Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Download or read book Clustering for Data Mining written by Boris Mirkin and published by CRC Press. This book was released on 2005-04-29 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Often considered more as an art than a science, the field of clustering has been dominated by learning through examples and by techniques chosen almost through trial-and-error. Even the most popular clustering methods--K-Means for partitioning the data set and Ward's method for hierarchical clustering--have lacked the theoretical attention that wou

Download or read book Clustering Algorithms written by John A. Hartigan and published by John Wiley & Sons. This book was released on 1975 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shows how Galileo, Newton, and Einstein tried to explain gravity. Discusses the concept of microgravity and NASA's research on gravity and microgravity.

Download or read book Data Mining in Bioinformatics written by Jason T. L. Wang and published by Springer Science & Business Media. This book was released on 2005 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written especially for computer scientists, all necessary biology is explained. Presents new techniques on gene expression data mining, gene mapping for disease detection, and phylogenetic knowledge discovery.

Download or read book Finite Mixture Models written by Geoffrey McLachlan and published by John Wiley & Sons. This book was released on 2004-03-22 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date, comprehensive account of major issues in finitemixture modeling This volume provides an up-to-date account of the theory andapplications of modeling via finite mixture distributions. With anemphasis on the applications of mixture models in both mainstreamanalysis and other areas such as unsupervised pattern recognition,speech recognition, and medical imaging, the book describes theformulations of the finite mixture approach, details itsmethodology, discusses aspects of its implementation, andillustrates its application in many common statisticalcontexts. Major issues discussed in this book include identifiabilityproblems, actual fitting of finite mixtures through use of the EMalgorithm, properties of the maximum likelihood estimators soobtained, assessment of the number of components to be used in themixture, and the applicability of asymptotic theory in providing abasis for the solutions to some of these problems. The author alsoconsiders how the EM algorithm can be scaled to handle the fittingof mixture models to very large databases, as in data miningapplications. This comprehensive, practical guide: * Provides more than 800 references-40% published since 1995 * Includes an appendix listing available mixture software * Links statistical literature with machine learning and patternrecognition literature * Contains more than 100 helpful graphs, charts, and tables Finite Mixture Models is an important resource for both applied andtheoretical statisticians as well as for researchers in the manyareas in which finite mixture models can be used to analyze data.

Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.

Download or read book Inference for Functional Data with Applications written by Lajos Horváth and published by Springer Science & Business Media. This book was released on 2012-05-08 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recently developed statistical methods and theory required for the application of the tools of functional data analysis to problems arising in geosciences, finance, economics and biology. It is concerned with inference based on second order statistics, especially those related to the functional principal component analysis. While it covers inference for independent and identically distributed functional data, its distinguishing feature is an in depth coverage of dependent functional data structures, including functional time series and spatially indexed functions. Specific inferential problems studied include two sample inference, change point analysis, tests for dependence in data and model residuals and functional prediction. All procedures are described algorithmically, illustrated on simulated and real data sets, and supported by a complete asymptotic theory. The book can be read at two levels. Readers interested primarily in methodology will find detailed descriptions of the methods and examples of their application. Researchers interested also in mathematical foundations will find carefully developed theory. The organization of the chapters makes it easy for the reader to choose an appropriate focus. The book introduces the requisite, and frequently used, Hilbert space formalism in a systematic manner. This will be useful to graduate or advanced undergraduate students seeking a self-contained introduction to the subject. Advanced researchers will find novel asymptotic arguments.

Download or read book Basics of Bioinformatics written by Rui Jiang and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate Statistical Methods in Bioinformatics Research, Association Analysis for Human Diseases: Methods and Examples, Data Mining and Knowledge Discovery Methods with Case Examples, Applied Bioinformatics Tools, Foundations for the Study of Structure and Function of Proteins, Computational Systems Biology Approaches for Deciphering Traditional Chinese Medicine, and Advanced Topics in Bioinformatics and Computational Biology. This book can serve as not only a primer for beginners in bioinformatics, but also a highly summarized yet systematic reference book for researchers in this field. Rui Jiang and Xuegong Zhang are both professors at the Department of Automation, Tsinghua University, China. Professor Michael Q. Zhang works at the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.

Download or read book Robust Statistics written by Frank R. Hampel and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Wiley-Interscience Paperback Series consists of selectedbooks that have been made more accessible to consumers in an effortto increase global appeal and general circulation. With these newunabridged softcover volumes, Wiley hopes to extend the lives ofthese works by making them available to future generations ofstatisticians, mathematicians, and scientists. "This is a nice book containing a wealth of information, much ofit due to the authors. . . . If an instructor designing such acourse wanted a textbook, this book would be the best choiceavailable. . . . There are many stimulating exercises, and the bookalso contains an excellent index and an extensive list ofreferences." —Technometrics "[This] book should be read carefully by anyone who isinterested in dealing with statistical models in a realisticfashion." —American Scientist Introducing concepts, theory, and applications, RobustStatistics is accessible to a broad audience, avoidingallusions to high-powered mathematics while emphasizing ideas,heuristics, and background. The text covers the approach based onthe influence function (the effect of an outlier on an estimater,for example) and related notions such as the breakdown point. Italso treats the change-of-variance function, fundamental conceptsand results in the framework of estimation of a single parameter,and applications to estimation of covariance matrices andregression parameters.

Download or read book Emerging Trends in IoT and Computing Technologies written by Suman Lata Tripathi and published by CRC Press. This book was released on 2024-08-29 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: Second International Conference on Emerging Trends in IOT and Computing Technologies (ICEICT – 2023) is organised with a vision to address the various issues to promote the creation of intelligent solution for the future. It is expected that researchers will bring new prospects for collaboration across disciplines and gain ideas facilitating novel concepts. Second International Conference of Emerging Trends in IoT and Computer Technologies (ICEICT-2023) is an inventive event organised in Goel Institute of Technology and Management, Lucknow, India, with motive to make available an open International forum for the researches, academicians, technocrats, scientist, engineers, industrialist and students around the globe to exchange their innovations and share the research outcomes which may lead the young researchers, academicians and industrialist to contribute to the global society. The conference ICEICT- 2023 is being organised at Goel Institute of Technology and Management, Lucknow, Uttar Pradesh, during 12-13 January 2024. It will feature world-class keynote speakers, special sessions, along with the regular/oral paper presentations. The conference welcomes paper submissions from researcher, practitioners, academicians and students will cover numerous tracks in the field of Computer Science and Engineering and associated research areas.

Download or read book IJCAI written by and published by . This book was released on 2007 with total page 1620 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Data Clustering Theory Algorithms and Applications Second Edition written by Guojun Gan and published by SIAM. This book was released on 2020-11-10 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data clustering, also known as cluster analysis, is an unsupervised process that divides a set of objects into homogeneous groups. Since the publication of the first edition of this monograph in 2007, development in the area has exploded, especially in clustering algorithms for big data and open-source software for cluster analysis. This second edition reflects these new developments, covers the basics of data clustering, includes a list of popular clustering algorithms, and provides program code that helps users implement clustering algorithms. Data Clustering: Theory, Algorithms and Applications, Second Edition will be of interest to researchers, practitioners, and data scientists as well as undergraduate and graduate students.

Download or read book Adaptation in Natural and Artificial Systems written by John H. Holland and published by MIT Press. This book was released on 1992-04-29 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic algorithms are playing an increasingly important role in studies of complex adaptive systems, ranging from adaptive agents in economic theory to the use of machine learning techniques in the design of complex devices such as aircraft turbines and integrated circuits. Adaptation in Natural and Artificial Systems is the book that initiated this field of study, presenting the theoretical foundations and exploring applications. In its most familiar form, adaptation is a biological process, whereby organisms evolve by rearranging genetic material to survive in environments confronting them. In this now classic work, Holland presents a mathematical model that allows for the nonlinearity of such complex interactions. He demonstrates the model's universality by applying it to economics, physiological psychology, game theory, and artificial intelligence and then outlines the way in which this approach modifies the traditional views of mathematical genetics. Initially applying his concepts to simply defined artificial systems with limited numbers of parameters, Holland goes on to explore their use in the study of a wide range of complex, naturally occuring processes, concentrating on systems having multiple factors that interact in nonlinear ways. Along the way he accounts for major effects of coadaptation and coevolution: the emergence of building blocks, or schemata, that are recombined and passed on to succeeding generations to provide, innovations and improvements.

Download or read book Model Based Clustering and Classification for Data Science written by Charles Bouveyron and published by Cambridge University Press. This book was released on 2019-07-25 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cluster analysis finds groups in data automatically. Most methods have been heuristic and leave open such central questions as: how many clusters are there? Which method should I use? How should I handle outliers? Classification assigns new observations to groups given previously classified observations, and also has open questions about parameter tuning, robustness and uncertainty assessment. This book frames cluster analysis and classification in terms of statistical models, thus yielding principled estimation, testing and prediction methods, and sound answers to the central questions. It builds the basic ideas in an accessible but rigorous way, with extensive data examples and R code; describes modern approaches to high-dimensional data and networks; and explains such recent advances as Bayesian regularization, non-Gaussian model-based clustering, cluster merging, variable selection, semi-supervised and robust classification, clustering of functional data, text and images, and co-clustering. Written for advanced undergraduates in data science, as well as researchers and practitioners, it assumes basic knowledge of multivariate calculus, linear algebra, probability and statistics.

Download or read book Fundamentals of Data Mining in Genomics and Proteomics written by Werner Dubitzky and published by Springer Science & Business Media. This book was released on 2007-04-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents state-of-the-art analytical methods from statistics and data mining for the analysis of high-throughput data from genomics and proteomics. It adopts an approach focusing on concepts and applications and presents key analytical techniques for the analysis of genomics and proteomics data by detailing their underlying principles, merits and limitations.