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Book Diagnostic Molecular Pathology

Download or read book Diagnostic Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2023-10-18 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. - Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more - Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient - Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient - Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease

Book Diagnostic Testing for Enteric Pathogens  An Issue of Clinics in Laboratory Medicine

Download or read book Diagnostic Testing for Enteric Pathogens An Issue of Clinics in Laboratory Medicine written by Alexander J. McAdam and published by Elsevier Health Sciences. This book was released on 2015-06-14 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue on Diagnostic Testing for Enteric Patholgens is led by two experts in the field of clinical pathology: Alexander J. McAdam and Collette Fitzgerald. Topics include Salmonella, Shigella and Yersinia; Escherichia coli; Campylobacter; Clostridium difficile; Use of markers of intestinal inflammation for diagnosis of infectious gastroenteritis; Antibiotic susceptibility testing of bacteria that cause gastroenteritis; Norovirus; Rotavirus; Intestinal Abebae; Intestinal coccidia and cryptosporidium; Intestinal microsporidia; and Multiplex PCR tests for gastroentieritis. An added features of this issues a Q and A on a controversial area in clinical microbiology, related to STI testing. Several participants from different fields each answer the same series of questions; specialists from clinical laboratory medicine, public health and clinical patient care participate. Each question is introduced by the lead Editors.

Book Clinical Pathology  An Issue of the Clinics in Laboratory Medicine E Book

Download or read book Clinical Pathology An Issue of the Clinics in Laboratory Medicine E Book written by Geza S Bodor and published by Elsevier Health Sciences. This book was released on 2018-08-19 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine will focus on Clinical Pathology and is edited by Geza S. Bodor. Topics include, but are not limited to, Steroid measurement / Salivary cortisol measurement, Protein testing by LCMSMS, LCMSMS in the Clinical Laboratory, Laboratory Standards for Clinical LCMSMS, The need to teach LCMSMS to clinical laboratory scientists, MALDI-TOF in the clinical laboratory, MALDI TOF MS in the clinical microbiology laboratory, LCMSMS method development consideration in clinical laboratory practice, Cancer diagnosis using mass spectrometry, Adulteration and LCMSMS drug testing, Diagnosis of inherited metabolic disorders using LCMSMS, Harmonization of LCMSMS protein assays, Vitamin D testing by LCMSMS versus by immunoassay, Pain management testing by LCMSMS, and Development of FDA approved clinical mass spectrometer.

Book Clinical Pathology and Diagnostic Testing

Download or read book Clinical Pathology and Diagnostic Testing written by Mary Jo Burkhard and published by Clinics: Veterinary Medicine. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive volume on clinical pathology and diagnostic techniques for the small animal practitioner! Topics will include pancreatic testing, renal function testing, diagnosis of small intestinal disorders, hypocalcemia of critical illness, lactate in clinical practice, cardiac biomarkers, disorders of iron metabolism, lymphoma diagnostics, coagulation disorders, molecular approaches to the diagnosis of infectious diseases, hepatobiliary disease, and much more!

Book Improving Diagnosis in Health Care

    Book Details:
  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release : 2015-12-29
  • ISBN : 0309377722
  • Pages : 473 pages

Download or read book Improving Diagnosis in Health Care written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2015-12-29 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.

Book Accurate Results in the Clinical Laboratory

Download or read book Accurate Results in the Clinical Laboratory written by Amitava Dasgupta and published by Newnes. This book was released on 2013-01-22 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical, easy-to-use guide, named to Doody's Core Titles 2013, addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care. Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management. - Named to Doody's Core Titles 2013, a collection development tool for health sciences libraries of all sizes, by Doody Enterprises - Practical information for both clinicians and laboratory scientists, presented in the form of tables and charts for easy reference - Focus on range and sources of interferences rather than details of toxicologic mechanisms which are well covered in toxicology textbooks - Covers interferences across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing

Book Laboratory Medicine Diagnosis of Disease in Clinical Laboratory 2 E

Download or read book Laboratory Medicine Diagnosis of Disease in Clinical Laboratory 2 E written by Michael Laposata and published by McGraw Hill Professional. This book was released on 2014-08-15 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete full-color guide to medical test selection and test result interpretation Laboratory Medicine is an essential text for medical students and residents studying clinical pathology, medical technology students, and for practitioners working in a clinical setting. By selecting the appropriate tests and interpreting the results correctly, physicians using this book should be able to optimize patient outcomes and reduce the cost of achieving a diagnosis. This full-color guide features an easy-to-follow, consistent presentation for each disease discussed. Chapters begin with a brief description of the disorder followed by a discussion that includes tables detailing the laboratory evaluation of specific disorders, and coverage of diagnosis, baseline tests to exclude diagnostic possibilities, and clinical indications that warrant further screening and special testing. Features Updated to reflect the most current information 46 laboratory methods presented in easy-to-understand illustrations which include information on the expense and complexity of the assays More than 200 tables and full-color algorithms encapsulate important information and facilitate understanding Full-color blood-smear micrographs demonstrate common abnormal morphologies of red blood cells Valuable learning aids in each chapter, including learning objectives, chapter outlines, and a general introduction Extensive table of Clinical Laboratory Reference Values showing the conversions between US and SI units for each value Coverage of genetic test options that are now commonly used in clinical practice

Book Diagnostic Molecular Pathology in Practice

Download or read book Diagnostic Molecular Pathology in Practice written by Iris Schrijver and published by Springer Science & Business Media. This book was released on 2011-09-09 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.

Book Laboratory Medicine

    Book Details:
  • Author : Michael Laposata
  • Publisher : McGraw Hill Professional
  • Release : 2012-09-01
  • ISBN : 0071811524
  • Pages : 485 pages

Download or read book Laboratory Medicine written by Michael Laposata and published by McGraw Hill Professional. This book was released on 2012-09-01 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete full-color guide to selecting the correct laboratory test and interpreting the results –- covering the entire field of clinical pathology A Doody's Core Title ESSENTIAL PURCHASE for 2011! "The editor and authors are well respected in their fields of expertise - this is an all-star cast....This book nicely fills the gap between comprehensive clinical laboratory science texts and the traditional and well-recognized, definitive laboratory medicine texts....It would be perfect for medical students and practicing physicians and it would be a perfect companion textbook for those teaching laboratory medicine in a medical school curriculum. 3 Stars."--Doody's Review Service Laboratory Medicine is the most comprehensive, user-friendly, and well-illustrated guide available for learning how to order the correct laboratory test and understand the clinical significance of the results. The book features an easy-to-follow, consistent presentation for each disease discussed. Chapters begin with a brief description of the disorder followed by a discussion that includes tables detailing the laboratory evaluation of specific disorders, diagnosis, baseline tests to exclude diagnostic possibilities, and clinical indications that warrant further screening and special testing. With new, increasingly expensive and complicated tests appearing almost daily, Laboratory Medicine is required reading for students and physicians who want to keep abreast of the latest testing procedures and maximize accuracy and patient safety. Features 36 clinical laboratory methods presented in easy-to-understand illustrations that include information on the expense and complexity of the assays More than 200 tables and full-color algorithms that encapsulate important information and facilitate understanding Full-color blood-smear micrographs that demonstrate common abnormal morphologies of red blood cells Valuable learning aids in each chapter, including learning objectives, chapter outlines, and a general introduction Logical systems-based organization that complements most textbooks 13-page table of Clinical Laboratory Reference Values that show the conversions between U.S. and SI units for each value Coverage that spans ALL of clinical pathology: Concepts in Laboratory Medicine; Methods, Autoimmune Disorders Involving the Connective Tissue and Immunodeficiency Diseases; Histocompatibility Testing and Transplantation; Infectious Diseases; Toxicology, Diseases of Infancy and Childhood; Blood Vessels; The Heart; Diseases of Red Blood Cells; Bleeding and Thrombotic Disorders; Transfusion Medicine; Diseases of White Blood Cells, Lymph Nodes, and Spleen; The Respiratory System; The Gastrointestinal Tract; The Liver and Biliary Tract; Pancreatic Disorders; The Kidney; Male Genital Tract; Female Genital System; Breast; The Endocrine System.

Book Clinical Pathology and Diagnostic Testing  An Issue of Veterinary Clinics  Small Animal Practice

Download or read book Clinical Pathology and Diagnostic Testing An Issue of Veterinary Clinics Small Animal Practice written by Mary Jo Burkhard and published by Elsevier Health Sciences. This book was released on 2013-11-28 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive volume on clinical pathology and diagnostic techniques for the small animal practitioner! Topics will include pancreatic testing, renal function testing, diagnosis of small intestinal disorders, hypocalcemia of critical illness, lactate in clinical practice, cardiac biomarkers, disorders of iron metabolism, lymphoma diagnostics, coagulation disorders, molecular approaches to the diagnosis of infectious diseases, hepatobiliary disease, and much more!

Book Clinical Chemistry

    Book Details:
  • Author : James H. Nichols, PhD, DABCC, FACB
  • Publisher : Demos Medical Publishing
  • Release : 2013-09-25
  • ISBN : 1617051896
  • Pages : 173 pages

Download or read book Clinical Chemistry written by James H. Nichols, PhD, DABCC, FACB and published by Demos Medical Publishing. This book was released on 2013-09-25 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: As with other volumes in the Diagnostic Standards of Care series, Clinical Chemistry focuses specifically on understanding potential problems and sources of error in management of the clinical chemistry testing procedures, how to anticipate and avoid such problems, and how to manage them if they occur. The discussions are concise, practical, specific, and problem-based so the book directly addresses the situations and issues faced by the clinical pathologist or other manager or staff member of the chemistry team. Discussion of each problem is augmented by a case discussion giving a real-world example of how the issue can occur and how it can be effectively dealt with by the manager. The goal is to support the pathologist, manager or technologist in providing the highest possible quality of care and effective, timely consultation to the clinical staff. Clinical Chemistry: Diagnostic Standards of Care features: Comprehensive coverage of key issues in achieving quality in all areas of clinical chemistry Includes chapters dedicated to point of care testing, pediatric testing, laboratory information systems and EHR integration, and outreach testing Numerous case examples and discussions give real-world illustrations of how problems occur and how to avoid them Coverage includes perspectives from the lab manager's and administrator's view An emphasis on identifying established, evidence-based standards in clinical chemistry Examples of errors which compromise patient safety across all major areas of clinical chemistry Pocket-sized for portability

Book Clinical Diagnostic Tests

    Book Details:
  • Author : Michael Laposata, MD, PhD
  • Publisher : Springer Publishing Company
  • Release : 2015-07-10
  • ISBN : 1620700832
  • Pages : 311 pages

Download or read book Clinical Diagnostic Tests written by Michael Laposata, MD, PhD and published by Springer Publishing Company. This book was released on 2015-07-10 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Diagnostic Tests is a convenient, quick-reference guide to common errors and pitfalls in test selection and result interpretation for practitioners and trainees in all areas of clinical medicine. Authored by recognized experts and educators in laboratory medicine, it provides timely, practical guidance about what to doÛand what not to doÛfor practitioners ordering or interpreting clinical tests. Each topic features a concise overview and summary followed by a list of bulleted Ïstandards of careÓ that will enable practitioners to quickly recognize and avert a potential problem. Organized for easy access to critical information, this pithy guide addresses all major issues practitioners are likely to encounter during their day-to-day clinical work. It is intended for practitioners in pathology, laboratory medicine, primary care as well as nurse practitioners and physician assistants. It is also a valuable resource for clinical trainees and students who need to learn effective, efficient use of the clinical lab in practice. Key Features: Provides practical guidance for avoiding common errors and pitfalls in lab test selection and interpretation Includes pithy overviews and recommendations for quick reference Written by expert authors and educators in laboratory medicine Presents bulleted Ïstandards of careÓ Serves as a concise, to-the-point teaching guide About the Author: Michael Laposata, MD, PhD , is Chair of Pathology, Director of Division of Laboratory Medicine and Clinical Laboratories, University of Texas Medical Branch, Galveston "

Book Molecular Diagnostics

    Book Details:
  • Author : Wayne W. Grody
  • Publisher : Academic Press
  • Release : 2009-11-06
  • ISBN : 0080919049
  • Pages : 518 pages

Download or read book Molecular Diagnostics written by Wayne W. Grody and published by Academic Press. This book was released on 2009-11-06 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. Molecular Diagnostics provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting. - Serves as the definitivereference for molecular pathologists worldwide - Covers a variety of molecular techniques including next generation sequencing, tumor somatic cell genotyping, infectious and genetic disease tecting, and pharmacogenetics - Discusses in the detail issues concerning quality assurance, regulation, ethics, and future directions for the science

Book Clinical Microbilogy

    Book Details:
  • Author : Charles W. Stratton
  • Publisher : Demos Medical Publishing
  • Release : 2011-07-10
  • ISBN : 1936287196
  • Pages : 165 pages

Download or read book Clinical Microbilogy written by Charles W. Stratton and published by Demos Medical Publishing. This book was released on 2011-07-10 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: "About the Diagnostic Standards of Care Series A key issue for every laboratory and individual laboratory practitioner is the assessment of risk and a current working knowledge of the standards of care established for diagnostic testing via guidelines, major studies and trials. The Diagnostic Standards of Care series presents an overview of the key diagnoses in clinical pathology using case examples to illustrate effective analysis of the case in light of current evidence and standards for the problem discussed. In addition to being practical diagnostic guides, these volumes will have a unique emphasis on quality assurance and evidence-based testing practices and the role of the pathologist in ensuring quality and patient safety. Clinical Microbiology addresses common medical errors seen in the clinical microbiology laboratory in order to show these errors to pathologists and laboratory technicians as well as clinicians. The goal is to allow such errors to be corrected by both individual effort and a systems approach in the laboratory. The book addresses potential medical errors in test ordering and specimen collection, testing in the laboratory, and reporting and interpretation of test results. Each of these phases can have an adverse impact on the diagnosis and treatment of an infectious disease if a medical error occurs. Potential medical errors are described and discussed in a clinical case-based learning format to effectively illustrate the conditions that contribute to these errors and enable the reader to recognize and avoid them in daily practice. Clinical Microbiology Features Descriptions of potential errors in test ordering and specimen collection in clinical microbiology Descriptions of potential errors in test performance in clinical microbiology Descriptions of potential errors in test reporting and interpretation in clinical microbiology Clinical case discussions provide "real world" illustrations of potential errors and how to anticipate and avoid them in practice Is pocket-sized for portability "

Book Microbiology and Molecular Diagnosis in Pathology

Download or read book Microbiology and Molecular Diagnosis in Pathology written by Audrey Wanger and published by Elsevier. This book was released on 2017-06-13 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiology and Molecular Diagnosis in Pathology: A Comprehensive Review for Board Preparation, Certification and Clinical Practice reviews all aspects of microbiology and molecular diagnostics essential to successfully passing the American Board of Pathology exam. This review book will also serve as a first resource for residents who want to become familiar with the diagnostic aspects of microbiology and molecular methods, as well as a refresher course for practicing pathologists. Opening chapters discuss issues of laboratory management, including quality control, biosafety, regulations, and proper handling and reporting of laboratory specimens. Review chapters give a quick overview of specific clinical infections as well as different types of bacteria, viruses, fungal infections, and infections caused by parasites. Following these, coverage focuses on diagnostic tools and specific tests: media for clinical microbiology, specific stains and tests for microbial identifications, susceptibility testing and use of antimicrobial agents, tests for detecting antibodies, antigens, and microbial infections. Two final chapters offer overviews on molecular diagnostics principles and methods as well as the application of molecular diagnostics in clinical practice. - Takes a practical and easy-to-read approach to understanding microbiology at an appropriate level for both board preparation as well as a professional refresher course - Covers all important clinical information found in larger textbooks in a more succinct and easy-to-understand manner - Covers essential concepts in microbiology in such a way that residents, fellows, and clinicians understand the methods and tests without having to become specialists in the field - Offers a quick overview of specific clinical infections as well as different types of bacteria, viruses, fungal infections, and infections caused by parasites