Download or read book Clinical Neuroendocrinology Neuropeptide Gpcrs written by Dylan Edwards and published by States Academic Press. This book was released on 2021-11-16 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The branch of biology which focuses on the relationship between the endocrine and the nervous system is termed as neuroendocrinology. The regulation of the activity of the hormones by the brain is studied within this field. The physiological processes in the body are regulated by a process known as neuroendocrine integration, wherein the endocrine and nervous system function together. The major neuroendocrine systems in the body are Hypothalamic-pituitary-adrenal axis (HPA axis), Hypothalamic-pituitary-thyroid axis (HPT axis), Hypothalamic-pituitary-gonadal axis (HPG axis) and Hypothalamic-neurohypophyseal system. GPCRs are G protein-coupled receptors, which can bind to numerous neuropeptides. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of neuroendocrinology. It presents the complex subject of neuropeptide GPCRs in the most comprehensible and easy to understand language. The extensive content of this book provides the readers with a thorough understanding of the subject.
Download or read book Neuropeptide GPCRs in neuroendocrinology written by Jae Young Seong and published by Frontiers E-books. This book was released on 2014-11-07 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human genome encompasses ˜ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic was to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that would illustrate the different facets of the studies currently conducted in this domain.
Download or read book Neuropeptide GPCRs in Neuroendocrinology Volume II written by Maria Lucia Narducci and published by Frontiers Media SA. This book was released on 2023-07-07 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Orphan G Protein Coupled Receptors and Novel Neuropeptides written by Olivier Civelli and published by Springer Science & Business Media. This book was released on 2008-05-15 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms. The chapters of this book review the latest research in the field, most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is set not only on their discovery but also on their functional significance. Since many of these neuropeptides are part of drug discovery programs, this book impacts academic as well as pharmaceutical research.
Download or read book Neuroendocrinology Recent Studies in Neuropeptide Gpcrs written by Dylan Edwards and published by . This book was released on 2022-09-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology is the branch of physiology which deals with the study of interactions between the endocrine system and the nervous system. It encompasses the way brain regulates the hormonal activity in the body. To regulate the physiological processes of the human body, the endocrine and nervous systems often act together and the process is known as neuroendocrine integration. Neuroendocrine system is a system by which hypothalamus maintains homeostasis by regulating metabolism, energy utilization, eating and drinking behavior, reproduction, blood pressure and osmolarity. G protein-coupled receptors (GPCRs) are the neuropeptide targets via which the intracellular signaling transduction pathways are activated. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of neuroendocrinology. It is an upcoming field of science that has undergone rapid development over the past few decades. This book is a resource guide for experts as well as students.
Download or read book Molecular Neuroendocrinology written by David Murphy and published by John Wiley & Sons. This book was released on 2016-01-19 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. The 19 chapters are divided into four sectors: A) describes and explores the genome, its evolution, expression and the mechanisms that contribute to protein, and hence biological, diversity. B) discusses the mechanisms that enhance peptide and protein diversity beyond what is encoded in the genome through post-translational modification. C) considers the molecular tools that today’s neuroendocrinologists can use to study the regulation and function of neuroendocrine genes within the context of the intact organism. D) presents a range of case studies that exemplify the state-of-the-art application of genomic technologies in physiological and behavioural experiments that seek to better understand complex biological processes. • Written by a team of internationally renowned researchers • Both print and enhanced e-book versions are available • Illustrated in full colour throughout This is the third volume in a new Series ‘Masterclass in Neuroendocrinology’ , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA
Download or read book Orphan G Protein Coupled Receptors and Novel Neuropeptides written by Olivier Civelli and published by Springer. This book was released on 2009-08-29 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms. The chapters of this book review the latest research in the field, most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is set not only on their discovery but also on their functional significance. Since many of these neuropeptides are part of drug discovery programs, this book impacts academic as well as pharmaceutical research.
Download or read book Clinical Neuroendocrinology written by Michael Wilkinson and published by Cambridge University Press. This book was released on 2019-01-03 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
Download or read book Molecular Neuroendocrinology written by David Murphy and published by John Wiley & Sons. This book was released on 2015-12-24 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Neuroendocrinology: From Genome to Physiology, provides researchers and students with a critical examination of the steps being taken to decipher genome complexity in the context of the expression, regulation and physiological functions of genes in neuroendocrine systems. The 19 chapters are divided into four sectors: A) describes and explores the genome, its evolution, expression and the mechanisms that contribute to protein, and hence biological, diversity. B) discusses the mechanisms that enhance peptide and protein diversity beyond what is encoded in the genome through post-translational modification. C) considers the molecular tools that today’s neuroendocrinologists can use to study the regulation and function of neuroendocrine genes within the context of the intact organism. D) presents a range of case studies that exemplify the state-of-the-art application of genomic technologies in physiological and behavioural experiments that seek to better understand complex biological processes. • Written by a team of internationally renowned researchers • Both print and enhanced e-book versions are available • Illustrated in full colour throughout This is the third volume in a new Series ‘Masterclass in Neuroendocrinology’ , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA
Download or read book Neuropeptides written by Lawrence J. Whalley and published by . This book was released on 1982 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Role of Neuropeptide Receptors in Neuroendocrinology written by Gilbert Holmes and published by . This book was released on 2022-09-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology is a branch of biology which is concerned with the functional and anatomical interactions between the endocrine system and the nervous system. Major neuroendocrine systems are hypothalamic-pituitary-adrenal axis, hypothalamic-pituitary-thyroid axis, hypothalamic-pituitary-gonadal axis and hypothalamic-neurohypophyseal system. Neuropeptide receptors are the G-protein coupled class that comprises of seven transmembrane receptors. Peptides are released into the synaptic cleft and they activate these receptors through high affinity binding and also mediate internal signaling events through cytoplasmic G-protein coupled effector. When these receptors are activated, this inhibits and activates a variety of second messenger systems which results in cell firing, phosphorylation and dephosphorylation events, modulation of membrane threshold and alteration of gene expression. This book covers in detail some existent theories about the role of neuropeptide receptors in neuroendocrinology. It presents researches and studies performed by experts across the globe. Students, researchers, experts and all associated with this field will benefit alike from this book.
Download or read book An Introduction to Neuroendocrinology written by and published by Cambridge University Press. This book was released on with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book What s New in Endocrinology written by Jeff M. P. Holly and published by Frontiers Media SA. This book was released on 2020-01-30 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Textbook of Energy Balance Neuropeptide Hormones and Neuroendocrine Function written by Eduardo A. Nillni and published by Springer. This book was released on 2018-07-20 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity. The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease. This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.
Download or read book Pediatric Endocrinology written by Mark A. Sperling and published by Elsevier Health Sciences. This book was released on 2008-06-05 with total page 909 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely updated, the new edition of this easy-to-reference text examines the physiological, biochemical, and genetic aspects of pediatric endocrine disorders. Leaders in the field discuss the hottest topics-including genetics, diabetes and obesity-impacting today’s endocrine practice, keeping you up to date. A user-friendly organization speeds you to the information you need, and conceptual illustrations and photographs depict the latest advances with consistency and clarity. It’s the guidance you need to provide effective, state-of-the-art care for your pediatric and neonatal patients. Examines the physiological, biochemical, and genetic aspects of endocrine disorders all in one convenient reference. Incorporates the importance of molecular biology as it relates to developmental and pediatric endocrinology. Offers expanded coverage of genetics, diabetes and obesity-topics of increasing concern in pediatric endocrinology today. Presents the work of many new contributors for fresh perspectives on the current state of pediatric endocrinology. Provides new tables of normal values and growth charts for monitoring your patients’ progress. Concepts, Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests and Imaging-making the material easy to navigate.
Download or read book Endocrine Pathology written by Stefano La Rosa and published by Springer Nature. This book was released on 2022-11-24 with total page 860 pages. Available in PDF, EPUB and Kindle. Book excerpt: This encyclopedia volume covers the complete field of endocrine pathology – from Acidophil Stem Cell Adenoma to Waterhouse-Friderichsen syndrome. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
