Download or read book Chip Based Common path Swept source Optical Coherence Tomography Device written by Lantian Chang and published by . This book was released on 2016 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Download or read book Progress in Optics written by Taco Visser and published by Elsevier. This book was released on 2021-04-16 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Optics, Volume 66, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. It contains five reviews of the latest developments in optics. - This volume covers medical imaging, physical optics, integrated optics, and quantum optics - Includes contributions from leading authorities in the field of optics - Presents timely, state-of-the-art reviews on advances in optics
Download or read book Full Field Common Path Optical Coherence Tomography System written by Ronald M. Friedman and published by . This book was released on 2007 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optical Coherence Tomography written by Wolfgang Drexler and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 1346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. This book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading research groups, in a style comprehensible to a broad audience.
Download or read book Sensors and Structured Beams in Optical Coherence Tomography written by Eun Song Kim and published by . This book was released on 2017 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is an emerging medical imaging technique that provides images of various tissue structures at micrometer scale resolution. A swept source laser which emits time-varying wavelengths light at a high-speed was developed that greatly improves OCT processing speed and image resolution. This dissertation presents system developments for swept source based OCT. I have designed and demonstrated three different OCT systems that can be used for diagnostic applications. First, I present a common-path OCT system with a cleaved optical fiber as a probe. The system is built as a tactile sensor for implementation in surgical robots. A tactile sensor, often referred to as a force sensor, is a device that is sensitive to applied force or pressure. Since the system has a high sensitivity to pressure and a compact size, the sensor is compatible with the surgical robots field which require fine force control. This new sensor may aid in diagnosing diseased tissue or cells by measuring their Young' s modulus. Secondly, an Angular/Longitudinal Doppler OCT system (ALD-OCT) was constructed to sense the rotation of an object. Previous work has shown, it is feasible to detect a linearly moving object by Doppler OCT. However, ALD-OCT, OCT utilizes a helical phase shape beam that, has been studied due to its distinct characteristics. An application of using a vortex beam is sensing a rotating object by measuring the angular Doppler shift from the beam reflected off the object. ALD-OCT can utilize depth resolved analysis and be implemented to detect helical shaped particles or the vorticity of blood flows under the skin or in the retina noninvasively. Lastly, we propose several designs of optical probes for a swept source OCT system. The designs of the GRIN lens bundle probes were presented to demonstrate angled illumination and detection techniques in OCT systems. The beam profiles of the output beams from the probes were analyzed theoretically using ABCD ray matrices. We present a method to measure the beam profile of a sweeping wavelength laser source, which can be applied to measure any optical probes connected to the swept source laser.
Download or read book Optical Coherence Tomography and Its Non medical Applications written by Michael Wang and published by BoD – Books on Demand. This book was released on 2020-05-27 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is a promising non-invasive non-contact 3D imaging technique that can be used to evaluate and inspect material surfaces, multilayer polymer films, fiber coils, and coatings. OCT can be used for the examination of cultural heritage objects and 3D imaging of microstructures. With subsurface 3D fingerprint imaging capability, OCT could be a valuable tool for enhancing security in biometric applications. OCT can also be used for the evaluation of fastener flushness for improving aerodynamic performance of high-speed aircraft. More and more OCT non-medical applications are emerging. In this book, we present some recent advancements in OCT technology and non-medical applications.
Download or read book SWEPT SOURCE OPTICAL COHERENCE written by Luoqin Yu and published by Open Dissertation Press. This book was released on 2017-01-26 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Swept Source Optical Coherence Tomography System Development for Bioimaging Applications" by Luoqin, Yu, 俞罗琴, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Optical coherence tomography (OCT) is an imaging modality with strengths in high-resolution, label-free, and noninvasive, which strategically fills the gap between ultrasound and microscopy and is superior for some biomedical applications. Swept source OCT (SS-OCT) improves system simplicity and sensitivity compared to previous versions of time domain OCT (TD-OCT) because of a static reference mirror and has faster imaging speed compared to spectral domain OCT (SD-OCT) because of a single photodetector and the availability of high-repetition-rate broadband lasers. Furthermore, functional spectroscopic OCT (SOCT) analyzes materials according to their specific optical properties at different wavelengths. Thus, by utilizing an ultra-wide band OCT and analyzing the sub-band images, it provides us a spectroscopic way to recognize materials. These kinds of newly developed OCT systems are quite promising in clinical bioimaging applications. One of the most commonly used swept sources in SS-OCT systems is the Fourier domain mode-locked (FDML) laser. It has a narrow instantaneous linewidth that improves imaging range, a broad sweeping range that renders high resolution, fast building up time that enables fast scanning, and a proper output power. However, traditional FDML lasers have limited sweeping range because of a limited amplification window of the gain medium that is usually unable to achieve an ultra-wide wavelength range. It hinders its way in spectroscopic imaging applications. Nevertheless, multi-band illumination can break through the bandwidth limitation of single-band SOCT. Consequently, developing swept sources with various output wavelength ranges is of high interest. The FDML lasers with output at 1.0 m range are most suitable in water-rich tissues where water dispersion and absorption are minimized. Thus, 1.0 m FDML laser cavities are firstly proposed with different amplification schemes to compare their performances. Dual-and tri-band SS-OCT systems for SOCT application are further investigated for contrast enhancement and differentiation of materials, such as lipid and porcine artery. Not only the output wavelength ranges of swept sources are of big concern, the swept speed is another bottleneck yet to be surpassed, especially for endoscopic applications. As the mechanical inertia of FDML lasers will limit the fundamental A-scan rate to hundreds of kilohertz, an ultrafast mode-locked laser together with inertia-free optical time-stretch mechanism is a promising alternative for SS-OCT endoscopic application. It has long imaging range and allows an A-scan rate up to more than ten megahertz. We further demonstrated this kind of amplified optical time-stretch (AOT) OCT with extensional application by endoscopic imaging. In summary, the goal of this thesis is to develop and extend SS-OCT systems in different aspects for various bioimaging applications. The SS-OCT systems with different advantages are proposed for spectroscopic and endoscopic imaging. Subjects: Imaging systems in medicine Optical coherence tomography
Download or read book Swept source Optical Coherence Tomography written by Kelvin Y. C. Teo and published by . This book was released on 2015 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Swept Source Optical Coherence Tomography written by Kelvin Yi Chong Teo and published by World Scientific Publishing Company. This book was released on 2015 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translations from Chinese popular literature of the late-imperial and early republican periods are still very rare, and selections that are devoted to a specific genre or dialect rarer still. These translations of traditional Hakka popular literature are not only a contribution to a broader knowledge of traditional Chinese folk literature, but also contribute to the study of Hakka culture as reflected in these racy songs and exciting narratives. This book is the first extensive selection in English of traditional Hakka mountain songs (shange) and long narrative ballads in various genres. One chapter is devoted to songs and ballads on Hakka migration to Taiwan and Southeast Asia in 18th to 20th centuries. The selection of mountain songs is primarily based on a collection compiled before 1949. The ballads selected focus on texts that were widely popular in late-Qing and early Republican times, but post-Liberation performances and new compositions have been included for contrast. All translations are provided with an introduction and annotations.
Download or read book Optical Coherence Tomography written by G. Coscas and published by Karger Medical and Scientific Publishers. This book was released on 2014-02-27 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of its many advantages optical coherence tomography (OCT) has revolutionized the way in which retinal diseases are screened and managed and how treatments are monitored. In this volume the latest developments and findings are presented by experts in their respective fields. After a short introduction covering the available equipment and the basic techniques, the imaging features of various pathological findings in retinal diseases are presented. The topics cover the outer layers including new modalities for choroid imaging, out-layer diseases such as the various types of macular degeneration, retinal diseases such as diabetic retinopathy and vascular occlusion, and retina and vitreous interface pathologies. The final chapters are dedicated to the practicality of using OCT for the pre- and postsurgical evaluation of the posterior segment and for the differential diagnosis of vitreoretinal diseases as well as in the management of patients with retinal and neuro-ophthalmological diseases. Making the essentials of the recently held ESASO course on OCT available in one volume, this publication is a must-read for experienced as well as trainee ophthalmologists who need to use OCT in their daily practice.
Download or read book Atlas of Swept Source OCT and OCT Angiography written by Youxin Chen and published by Springer Nature. This book was released on 2023-03-01 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to explain this new technology and its advantages over previous imaging devices and to illustrate how it may be used in to define eye diseases, and in their treatment and facilitate treatment options. This atlas introduces the technical principles of SS-OCT imaging, OCTA stratification algorithm, and blood flow quantization. Through a collection of images and annotation of the microstructures of both the normal fundus and diseased eyes (for example, vitreous related disease, retinal diseased and choroidal disease) captured on SS-OCT to deepen the understanding of this new technology, as well as the interpretation of images. This atlas serves as a practical guide and is written for retinal specialist and clinicians with an interest in retinal diseases.
Download or read book High Speed Swept Source Optical Coherence Tomography Handheld Instrument at 1310nm for Point of care Imaging written by Patrick Wai-Kit Yiu and published by . This book was released on 2018 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is a novel biomedical imaging technique that functions as a type of "optical biopsy" by using low coherence interferometry to non-invasively generate high resolution cross-sectional images of tissue in real time. OCT has become a standard diagnostic tool in ophthalmology and investigators have demonstrated OCT in a variety of biomedical applications including cardiology, gastroenterology, dermatology, and urology. Recent research advances in swept source lasers have enabled swept source OCT (SS-OCT) to achieve imaging speeds 5-50x faster than commercially available spectral domain OCT (SD-OCT) systems. This thesis describes the design of a handheld SS-OCT instrument for portable-real-time imaging in situ at the point of care. Traditional OCT devices require bulky table-mounted systems, but the handheld device has the potential to be used as an advanced point-of-care diagnostic instrument in primary care settings or intraoperatively. The combination of the wide scanning angle in the handheld and the high imaging speed of SS-OCT could allow for screening of pathology with a single volumetric data set spanning the areas of interest on the patient. The compact, easy-to-use form factor could enable the adoption of SS-OCT in settings like primary care clinics or the surgical theater where space is limited. Emergent applications can include intraoperative assessment of kidney transplant viability, as many donor kidneys suffer ischemic insult while awaiting transplant and there is a critical clinical need for a reliable, real-time assay to evaluate donor kidney viability and predict post-transplant outcome.
Download or read book Full Range Swept Source Optical Coherence Tomography with Ultra Small Fiber Probes for Biomedical Imaging written by Youxin Mao and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Full Range Swept-Source Optical Coherence Tomography with Ultra Small Fiber Probes for Biomedical Imaging.
Download or read book Optical Coherence Tomography written by Mark E. Brezinski and published by Elsevier. This book was released on 2006-08-25 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical Coherence Tomography gives a broad treatment of the subject which will include 1)the optics, science, and physics needed to understand the technology 2) a description of applications with a critical look at how the technology will successfully address actual clinical need, and 3) a discussion of delivery of OCT to the patient, FDA approval and comparisons with available competing technologies. The required mathematical rigor will be present where needed but be presented in such a way that it will not prevent non-scientists and non-engineers from gaining a basic understanding of OCT and the applications as well as the issues of bringing the technology to the market. - Optical Coherence Tomography is a new medical high-resolution imaging technology which offers distinct advantages over current medical imaging technologies and is attracting a large number of researchers. - Provides non-scientists and non-engineers basic understanding of Optical Coherence Tomography applications and issues.
Download or read book Optical Coherence Tomography written by Jianbing Xu and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Optical Coherence Tomography: From System Design to Spectroscopic Applications" by Jianbing, Xu, 徐鉴冰, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Optical coherence tomography (OCT), as a newly developed imaging modality, has attracted significant attention due to its capability to obtain the cross-sectional information of biological tissues in a non-invasive way, with resolution in the range of several micrometers. The third-generation swept source OCT (SS-OCT), is superior in the speed, imaging range and signal-to-noise ratio (SNR) compared with the previous time-domain OCT (TD-OCT) and spectral domain OCT (SD-OCT), and therefore forms our research focus. In this thesis, for the first time, I investigate the deployment of Fourier domain mode-locked (FDML) swept laser by utilizing the bismuth-based erbium doper fiber (Bi-EDF) with a sweeping bandwidth of 81nm achieved. Following, fiber Raman amplifier (FRA) is also investigated by employing multiple Raman pumps. The tuning range is 111.8nm, which is much larger than the previous reported Raman pumped FDML in the 1550nm region. Imaging was performed to validate the feasibility of the proposed schemes for the SS-OCT applications, respectively. In addition to the FDML swept laser cavity design, speckle noise reduction is also of great importance in OCT, which can significantly improve the visibility of the obtained OCT images. I demonstrate two different speckle reduction methods for OCT applications, which are superior in suppressing speckle noise and reserving the one-dimensional (1D) and two-dimensional (2D) signal information, respectively. Applying the proposed wavelet domain compounding (WDC) and contourlet shrinkage method to despeckle the OCT images, the visibility of the OCT images was significantly improved, with negligible edge preservation compromise. Spectroscopic information is also of interest to many researchers as it provides additional spectroscopic contrast, which on one hand, will improve the visualization of the images, and on the other hand, will enable the classification of different tissue types and help the process of discrimination between invasive and noninvasive tumors. Compared with our previous reported work about dual-band spectroscopic OCT based on optical parametric amplifier (OPA) to generate another idler band, which will be used as the second band for dual-band spectroscopic analysis, I further extend the dual-band spectroscopic OCT to the endoscopic applications, and investigate the dual-band FDML swept laser configuration based on a custom-designed dual-channel driver to synchronize the two different wavelength bands, centered at 1310 and 1550 nm, respectively. OCT Images for different bands are captured and post-processed by coding the spectral difference in different colors. In short, in this thesis, the investigations of OCT range from system design, speckle reduction to the spectroscopic applications. All these research efforts will extend the current FDML techniques for a wide range of SS-OCT applications. These schemes may be useful in OCT swept laser source build up, speckle noise reduction, and the extension of spectroscopic analysis. DOI: 10.5353/th_b5317037 Subjects: Optical coherence tomography
Download or read book Swept Source Optical Coherence Tomography System Development for Bioimaging Applications written by 俞罗琴 and published by . This book was released on 2015 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt:
