Download or read book Characterization of the Glypican Receptor Receptor Function written by Bart De Cat and published by Leuven University Press. This book was released on 2004-09 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Extracellular Matrix Pathobiology and Signaling written by Nikos Karamanos and published by Walter de Gruyter. This book was released on 2012-08-31 with total page 940 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decades cell biology and biological chemistry have increasingly turned their attention to the space between cells and revealed an elaborate network of macromolecules essential for structural support, cell adhesion and signaling. This comprehensive handbook of the extracellular matrix will give an overview of the current state of knowledge of matrix components (structure and function), their role in heath and disease (matrix pathobiology) and new aspects related to pharmacological targeting. It will provide an introduction to the extracellular matrix and detailed sections and chapters on: Importance of extracellular matrix in health and disease Matrix proteoglycans (aggrecan, versican, perlecan, SLRPs, syndecans, glypicans, serglycin) Matrix proteinases (remodeling, would healing, regulatory roles in health and disease, metalloproteinases, cystein proteases, plasmin and plasminogen activator system) Glycobiology (hyaluronan and sulfated glycosaminoglycans in cancer, inflammation and metabolic control) Collagens (supramolecular assembly, proteins binding collagen, scaffolds, bacterial and mutated collagens, procollagen proteinases) Cell surface receptors (integrins, syndecans, mechanical strain and TGFb, CD44 and DDR). Biotechnological and pharmacological outlook (matrix regulation by growth factors, hyaluronidases, pathobiology, disease targeting, delivery systems, EMT and proteomics). "The book Extracellular Matrix: Pathobiology and Signaling provides a comprehensive and up to date collection of very relevant topics for understanding the various facets of extracellular matrix and its interactions with cells in normal tissue as well as in disease. It represents the current front-line and will serve as a reference for extracellular matrix and posttranslational modifications." Dick Heinegård, Department of Clinical Sciences Lund, Section Rheumatology, Lund University, Sweden

Download or read book Huntington s Disease written by Jurgen Lemiere and published by Leuven University Press. This book was released on 2004 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Ph.D. dissertation. Huntington's Disease (HD) is a dominantly inherited late onset neurodegenerative disorder, initially affecting the basal ganglia and especially the head of the caudate nucleus. Eventually, atrophy is more diffuse extending to the cerebral cortex and other brain nuclei. A triad of progressive motor, cognitive, and emotional symptoms characterizes adult onset HD. Contents include: General Introduction and Aims of the Study, Cognitive Changes in Patients with HD and Asymptomatic Carriers of the HD Mutation, Recent Memory and Recognition Memory in Huntington's Disease, Habitual Learning in Huntington's and Parkinson's Disease, Effect of Oral Creatine Supplementation on Cognition in HD, General Summary and Perspectives.

Download or read book EGFR Activity as a Determinant of Response to EGFR targeted Therapy written by Sandra Van Schaeybroeck and published by Leuven University Press. This book was released on 2006 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Axon Growth Injury and Regeneration in the Fly Brain written by Maarten Leyssen and published by Leuven University Press. This book was released on 2006 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Physiological Study of Presenilins and Baces Two Proteases Involved in the Pathogenesis of Alzheimer s Disease written by Jos Tournoy and published by Leuven University Press. This book was released on 2006 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Protein Phosphatase 1 Binding Motifs written by Paulina Wakula and published by Leuven University Press. This book was released on 2006 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cell Repopulation of Bioprosthetic Heart Valves written by Jessa Yperman and published by Leuven University Press. This book was released on 2006 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Photoproduction of Vitamin D3 and Activation into 1a 25 Dihydroxyvitamin D3 in Human Epiderman Keratinocytes Dermal Fibroblasts and Other Cells written by Katleen Vantieghem and published by Leuven University Press. This book was released on 2006 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Ciz As a Fusion Partner for Tet proteins in Leukemia written by Hilde Janssen and published by Leuven University Press. This book was released on 2006-12-30 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Experimental Evaluation of the Host Immune Response to Xenogenic Bio derived Collagen Grafts in Rodent Models written by Fang Zheng and published by Leuven University Press. This book was released on 2006-09 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nitric Oxide and Cytochrome P450 Signaling in Experimental Pulmonary Hypertension written by Peter Pokreisz and published by Leuven University Press. This book was released on 2006 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Midkine From Embryogenesis to Pathogenesis and Therapy written by Mine Ergüven and published by Springer Science & Business Media. This book was released on 2012-06-12 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carl Edward Sagan’s (1934-1996) one of the famous quotation was “Who are we? We find that we live on an insignificant planet of a humdrum star lost in a galaxy tucked away in some forgotten corner of a universe in which there are far more galaxies than people.“ From past to date, well-known molecules, enzymes, proteins, lipids and carbohydrates are studied in the pathogenesis of several diseases both as a diagnostic/prognostic biomarker and therapeutic agent. The underlying mechanism of unexplained diseases and failure of therapies are frequently studied with well-known biomarkers, but remain unclear in many cases. As Dr. Sagan said other keys are still waiting to be known in some forgotten corner of a body universe, we find strength to propose that one of them can be the growth factor with cytokine activity named “Midkine” This book summarizes the extensive up-to-date literature overeview with the lastest work of experts about midkine in a detailed format that conveys its role as both a pathologic factor and therapeutic agent.

Download or read book Electrical Brain Stimulation in Psychiatric Disorders Contributions from Research in Animal Models written by Kris Van Kuyck and published by Leuven University Press. This book was released on 2006 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Download or read book Generation and Characterization of a Mouse Model for a Sodium Channel Based Long QT Syndrome LQT3 written by Dieter Nuyens and published by Leuven University Press. This book was released on 2006 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Macromolecular Protein Complexes II Structure and Function written by J. Robin Harris and published by Springer Nature. This book was released on 2020-01-14 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book follows on from Volume 83 in the SCBI series (“Macromolecular Protein Complexes”), and addresses several important topics (such as the Proteasome, Anaphase Promoting Complex, Ribosome and Apoptosome) that were not previously included, together with a number of additional exciting topics in this rapidly expanding field of study. Although the first SCBI Protein Complex book focused on soluble protein complexes, the second (Vol. 87)addressed Membrane Complexes, and the third (Vol. 88) put the spotlight on Viral Protein and Nucleoprotein Complexes, a number of membrane, virus and even fibrillar protein complexes have been be considered for inclusion in the present book. A further book is also under preparation that follows the same pattern, in an attempt to provide a thorough coverage of the subject. Chapter 9 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.