Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Download or read book Tissue Barriers in Disease Injury and Regeneration written by Nikolai V. Gorbunov and published by Elsevier. This book was released on 2021-06-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Barriers in Disease, Injury and Regeneration focuses on the molecular and cellular fundamentals of homeostatic and defense responses of tissue barriers, covering the damaging impacts and exposure to pathogens and engineered nanomaterials. Sections emphasize the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells, along with reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and metabolic status. Other sections cover the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, vasculature of blood-tissue barriers, and more. - Includes special emphasis on the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells in the development of reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and in metabolic status - Examines the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, the vasculature of blood-tissue barriers, and mucosa and external epithelium

Download or read book Apoptosis and Beyond written by James A. Radosevich and published by John Wiley & Sons. This book was released on 2018-09-18 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death. Covers all known processes that dying cells undergo Provides extensive coverage of a topic not fully covered before Offers chapters written by top researchers in the field Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.

Download or read book Cellular Injury written by A. V. S. de Reuck and published by John Wiley & Sons. This book was released on 2009-09-16 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Ultrastructural Pathology written by Norman F. Cheville and published by John Wiley & Sons. This book was released on 2009-06-30 with total page 997 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrastructural Pathology

Download or read book Inflammatory Atherosclerosis written by Richard James Frink and published by Heart Research Foundation Sacrament. This book was released on 2002 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Download or read book Angiogenesis written by Michael E. Maragoudakis and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis is a multistep process, which involves activation, proliferation and directed migration of endothelial cells to form new capillaries from existing vessels. Under physiological conditions, in the adult organisms angiogenesis is extremely slow, yet it can be activated for a limited time only in situations such as ovulation or wound healing. In a number of disease states, however, there is a derangement of angiogenesis, which can contribute to the pathology of these conditions. Hence, understanding the molecular biology of endothelial cell activation and differentiation and the mechanisms involved in the regulation of angiogenesis, could explain the derangement in disease states and also provide the basis for developing promoters or suppressors of angiogenesis for clinical applications. This book contains the proceedings of the NATO Advanced Study Institute on "Angiogenesis: Molecular Biology, Oinical Aspects" held in Rhodes, Greece, from June 16-27, 1993. This meeting was a comprehensive review of the various aspects of angiogenesis such as embryonic development, endothelial cell heterogeneity and tissue specificity, molecular biology of endothelial cell, mechanisms for the regulation of angiogenesis, disease states in which angiogenesis is involved and potential application of promoters or suppressors of angiogenesis. The presentations and discussions of the meeting provided an opportunity for investigators from many different areas of basic science and medicine to exchange information, evaluate the present status and provide future research directions in the field of angiogenesis.

Download or read book Cell Calcium Metabolism written by Gary Fiskum and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: A widespread appreciation for the role that calcium plays in cell physiology and patho physiology has now been achieved due to the pioneering studies of many of the scientists who attended the VIIth International Spring Symposium on Health Sciences at George Washington University in Washington, D. C. The participants in this unique meeting rep resented diverse fields of basic and clinical research, such as molecular physiology, oncology, molecular genetics, cardiology, bioenergetics, pathology, and endocrinology. The content of the proceedings of the symposium represents work in these and other areas of biomedical research. Organization of the book is aimed at striking a balance between the biochemistry 2 and physiology of normal cell Ca + metabolism and the pathological consequences of al 2 terations in cell Ca + homeostasis. The first section of the book is devoted to the transport mechanisms responsible for 2 2 regulating intracellular Ca + and the pharmacological modalities for controlling cell Ca + . Particular attention is given to the molecular basis for plasma membrane transport activities, 2 2 including the ATP-driven Ca + pump, the Na + -Ca + exchange system, and voltage sensitive 2 Ca + channels. The second section covers the exciting relationships between phosphoinositide metab 2 olism, signal transduction, and cell Ca + metabolism. This section begins with an eloquent overview by Professor Michael Berridge, who was the keynote speaker at the symposium and the recipient of the scientific merit award.

Download or read book Cellular Injury in Liver Diseases written by Wen-Xing Ding and published by Springer. This book was released on 2017-05-16 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume has gathered together some of the world’s experts on cell death in liver diseases, covering topics on a variety of types of liver injury. Specifically, the chapters of this volume describe drug and virus-mediated hepatocyte injury, alcohol, lipid and bile acid-induced hepatocyte injury in addition to ischemia-reperfusion-mediated liver injury. The authors link these different types of liver injury to the commonly associated liver inflammation, fibrosis and tumorigenesis. Other topics explored include the various forms of cell death and cell survival pathways that have been identified in the liver, such as apoptosis, necroptosis, pryoptosis and autophagy. This book, along with its companion volume, Molecules, Systems and Signaling in Hepatic Cell Death, provides a thorough and comprehensive discussion on the topic of cell death and liver disease. Cellular Injury in Liver Diseases is an essential addition to the Cell Death in Biology and Diseases series and will appeal to scientists, clinicians and those doing research for drug discovery.

Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Download or read book Pathology The Big Picture written by William Kemp and published by McGraw Hill Professional. This book was released on 2007-08-22 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get the BIG PICTURE of Pathology - and focus on what you really need to know to score high on the course and board exam If you want a streamlined and definitive look at Pathology - one with just the right balance of information to give you the edge at exam time - turn to Pathology: The Big Picture. You'll find a succinct, user-friendly presentation especially designed to make even the most complex concept understandable in the shortest amount of study time possible. This perfect pictorial and textual overview of Pathology delivers: A “Big Picture” emphasis on what you must know verses “what's nice to know” Expert authorship by award-winning, active instructors Coverage of the full range of pathology topics - everything from cellular adaptations and injury to genetic disorders to inflammation to diseases of immunity Magnificent 4-color illustrations Numerous summary tables and figures for quick reference and rapid retention of even the most difficult topic Highlighted key concepts that underscore integral aspects of histology (key concepts are also listed in a table at the end of each chapter) USMLE-type questions, answers, and explanations to help you anticipate what you'll encounter on the exams And much more!

Download or read book Pathology written by John H. Holliman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: These notes were developed to assist in the review of the basic science of pathology for those students preparing to sit for various national proficiency examinations which include, as part of their content, material dealing with general and systemic pathology. As such, the notes are not intended to replace the many fine textbooks of pathology whose scope, detail, and mission are more suited to the in depth study of pathology. Rather, these notes are intended to serve as "memory joggers" to rekindle and refresh the mind of some of the salient features of various disease processes and to point out to the student possible areas of weakness which they may need to address in more detail by referring to one of the standard textbooks of pathology. In this regard, these notes are presented in an organized and sensible (we hope!) outline format which is intended to allow systematic review of the material in a reasonable amount of time. In an effort to contain cost and avoid undue repetition with other volumes of the Oklahoma Notes series, some topics that are generally covered in most standard pathology courses as well as illustrative material have been omitted from the present edition. The authors would like to extend our sincere gratitude to the faculty and staff of the Department of Pathology for their ideas, support, and assistance during the preparation of these notes. In particular, we would like to thank Drs. K.

Download or read book Pathology Secrets written by Ivan Damjanov and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: A two-color page layout, portable size, and a list of the "Top 100 Secrets" in pathology help students and residents to better meet the challenges they face today. They will find all of the features they rely on the Secret Series® for-a question-and-answer format, lists, mnemonics, and tables and an informal tone that make reference fast and easy. No matter what questions arise in practice or while preparing for boards, this 3rd Edition has the answers-in print and online. Uses bulleted lists, tables, short answers, and a highly detailed index to expedite reference. Features 20 new figures, pearls, tips, memory aids, and "secrets" from the experts. Covers all of today's most common procedures and techniques. Includes a list of the "Top 100 Secrets" to keep in mind during a rotation or residency. Features a compact, trim size (5 1/4" x 8 1/2") for enhanced portability. Makes information easier to find with a two-color page layout and "Key Points" boxes. Identifies useful websites to make it easy to find additional information on a specific topic and provides live links in the online version. Self Assessment exercises and matching Q&A for every chapter online with Student Consult to prepare for exams and focus your study on particular areas that you need the most. Includes STUDENT CONSULT access! www.studentconsult.com is an innovative website that allows you to build a personalized, fully integrated, online library, where you'll find. The entire contents of every STUDENT CONSULT title you purchase. Powerful search capabilities- View all excerpts relevant to keyword or subject searches (up to 300 words per hit) from every book in the series. Image library POCKETConsult- Download portions of your personal library onto your handheld device. Student resources- Sharpen your skills, stay informed, and have fun! More!