Download or read book Mechanisms of Immune Regulation written by Richard D. Granstein and published by S. Karger AG (Switzerland). This book was released on 1994 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the topics reviewed are T and B cell tolerance, clonal deletion, suppressor cells, mechanisms of immune privileged sites and experimental models of tumor immunity. Oral tolerance, ultraviolet radiation and photosensitized effects on immunity, allograft management, T cell vaccination and regulation of immunity with T cell epitopes are discussed from the point of view of possible therapeutic application.

Download or read book Molecular Mechanisms of Dendritic Cell Mediated Immune Tolerance and Autoimmunity written by Fang Zhou and published by Frontiers Media SA. This book was released on 2024-04-09 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendritic cells (DCs) play a critical role in immune system, as they are necessary both for innate and adaptive immunity. According to their function, dendritic cells can be classified in immune tolerogenic or inflammatory DCs. DCs have been shown to regulate T cell-mediated immune responses and lead to immune tolerance and autoimmunity. For example, immune-tolerogenic DCs facilitate the development of regulatory T cells and inhibit T helper 17-mediated autoimmunity in mice with experimental autoimmune encephalomyelitis. Moreover, inflammatory DCs activate CD8+ and CD4+ T cells and elicit T cell-mediated inflammatory immune responses in vivo. However, the molecular and cellular mechanisms underlying DC-mediated immune tolerance and autoimmunity are still obscure.

Download or read book Textbook of Hemophilia written by Christine A. Lee and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only up-to-date definitive reference source onhemophilia This book is an invaluable resource that provides an overview ofall aspects of the care of patients with haemophilia. Covering how to assess both bleeding children and adults,Haemophilia A and B, molecular basis of the disease, the role offactors in coagulation, epidemiology, pharmacokinetics, andtreatment of inhibitors. There will also be a section onmusculoskeletal aspects of haemophilia as well as newerdevelopments such as gene therapy and rare bleedingdisorders. Textbook of Hemophilia is ideal for: Trainees and residents in hematology Hematologists in practice Specialists working in thrombosis and hemostasis as well astransfusion medicine Why Buy This Book? The only up-to-date definitive reference source onhemophilia Essential for all those managing hemophilia patients Detailed guidance on assessment, diagnosis, management andtreatment Advice for everyday clinical questions Edited by three of the world’s leading experts onhemophilia

Download or read book Immunopharmacology written by Manzoor M. Khan and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.

Download or read book Cellular and Molecular Immunology E Book written by Abul K. Abbas and published by Elsevier Health Sciences. This book was released on 2021-02-19 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Well-written, readable, and superbly illustrated, Cellular and Molecular Immunology, 10th Edition, continues the tradition of excellence established through multiple editions of this bestselling text. Offering an unparalleled introduction to this complex field, it retains a practical, clinical focus while updating and revising all content to ensure clarity and comprehension, bringing readers fully up to date with new and emerging information in this challenging area. It's an ideal resource for medical, graduate, and undergraduate students, as well as a trusted reference for physicians and scientists. - Highlights the implications of immunologic science for the management of human disease, emphasizing clinical relevance throughout. - Employs a highly accessible writing style that makes difficult concepts easier to understand, and provides clear implications of immunologic science to the management of human disease and clinical practice. - Features updates from cover to cover, including new information on intracellular sensors of innate immunity, therapeutic use of monoclonal antibodies, regulation of migration events during T cell-B cell interactions, regulatory and transcriptional events in germinal center formation, immunology of infectious diseases including coronaviruses, human immunodeficiency disorders, and immunology of HIV. - Provides a highly visual, full-color description of the key immunologic and molecular processes with a fully updated, comprehensive, and consistent art program, including many new and extensively revised illustrations. - Helps readers grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions. - Includes summary boxes that assist with rapid review and mastery of key material. - Evolve Instructor site with an image and test bank is available to instructors through their Elsevier sales rep or via request at https://evolve.elsevier.com.

Download or read book The Saint Chopra Guide to Inpatient Medicine written by Sanjay Saint and published by Oxford University Press, USA. This book was released on 2018 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by: Clinical clerkship in inpatient medicine / Sanjay Saint. 3rd ed. c2010.

Download or read book Congenital Bleeding Disorders written by Akbar Dorgalaleh and published by Springer. This book was released on 2018-07-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.

Download or read book Textbook of Hemophilia written by Christine A. Lee and published by John Wiley & Sons. This book was released on 2014-04-22 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Hemophilia, 3rd edition Edited by Christine A. Lee, MA, MD, DSc, FRCP, FRCPath, FRCOG Emeritus Professor of Haemophilia, University of London, London, UK Erik E. Berntorp, MD, PhD Professor of Coagulation Medicine, Lund University Malmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, Sweden W. Keith Hoots, MD Director, Division of Blood Diseases and Resources, National Heart, Lung and Blood Institute National Institutes of Health, Bethesda, MD; Professor of Pediatrics and Internal Medicine, University of Texas Medical School at Houston, Houston, TX, USA Without doubt, Textbook of Hemophilia, 3rd edition is the definitive reference source on all aspects of haemophilia including diagnosis, management and treatment. Edited by three, world-renowned experts on haemophilia, this completely revised resource features chapters written by over 60 international contributors with international expertise in caring for haemophilia patients. Textbook of Hemophilia, 3rd edition Features eight new chapters, covering individualised dosing, vCJD and haemophilia, new drugs in the pipeline, and surgery in inhibitor patients Presents new developments, such as gene therapy Highlights controversial issues and provides advice for everyday clinical questions Represents essential reading for all healthcare professionals involved in the care of those with haemophilia Titles of related interest Hemophilia and Hemostasis: A Case-Based Approach to Management, 2nd Edition Ma, ISBN: 9780470659762 Current and Future Issues in Hemophilia Care Rodriguez-Merchan, ISBN: 9780470670576 www.wiley.com/go/hematology

Download or read book NIH Almanac written by National Institutes of Health (U.S.). Division of Public Information and published by . This book was released on 1999 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Inducing Immune Tolerance to Therapeutic Proteins Cells and Tissues written by Luis Graca and published by Frontiers Media SA. This book was released on 2021-12-20 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Induction of immune tolerance Addressing unmet medical need in immune mediated diseases and immune responses to biologics written by Amy Rosenberg and published by Frontiers Media SA. This book was released on 2023-09-25 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1996 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1972 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Download or read book A Guide to Human Gene Therapy written by Roland W. Herzog and published by World Scientific. This book was released on 2010 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Non-viral gene therapy / Sean M. Sullivan -- 2. Adenoviral vectors / Stuart A. Nicklin and Andrew H. Baker -- 3. Retroviral vectors and integration analysis / Cynthia C. Bartholomae [und weitere] -- 4. Lentiviral vectors / Janka Matrai, Marinee K.L. Chuah and Thierry VandenDriessche -- 5. Herpes simplex virus vectors / William F. Goins [und weitere] -- 6. Adeno-Associated Viral (AAV) vectors / Nicholas Muzyczka -- 7. Regulatory RNA in gene therapy / Alfred. S. Lewin -- 8. DNA integrating vectors (Transposon, Integrase) / Lauren E. Woodard and Michele P. Calos -- 9. Homologous recombination and targeted gene modification for gene therapy / Matthew Porteus -- 10. Gene switches for pre-clinical studies in gene therapy / Caroline Le Guiner [und weitere] -- 11. Gene therapy for central nervous system disorders / Deborah Young and Patricia A. Lawlor -- 12. Gene therapy of hemoglobinopathies / Angela E. Rivers and Arun Srivastava -- 13. Gene therapy for primary immunodeficiencies / Aisha Sauer, Barbara Cassani and Alessandro Aiuti -- 14. Gene therapy for hemophilia / David Markusic, Babak Moghimi and Roland Herzog -- 15. Gene therapy for obesity and diabetes / Sergei Zolotukhin and Clive H. Wasserfall -- 16. Gene therapy for Duchenne muscular dystrophy / Takashi Okada and Shin'ichi Takeda -- 17. Cancer gene therapy / Kirsten A.K. Weigel-Van Aken -- 18. Gene therapy for autoimmune disorders / Daniel F. Gaddy, Melanie A. Ruffner and Paul D. Robbins -- 19. Gene therapy for inherited metabolic storage diseases / Cathryn Mah -- 20. Retinal diseases / Shannon E. Boye, Sanford L. Boye and William W. Hauswirth -- 21. A brief guide to gene therapy treatments for pulmonary diseases / Ashley T. Martino, Christian Mueller and Terence R. Flotte -- 22. Cardiovascular disease / Darin J. Falk, Cathryn S. Mah and Barry J. Byrne

Download or read book Liver Immunology written by M. Eric Gershwin and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Immunology: Principles and Practice, Second Edition begins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters that provide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediated liver disease helps provide context for how these diseases affect the patient overall. In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases -- primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome – are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others. This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients. Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Edition will again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases. This volume will again be a must-read for clinicians at all levels, investigators and students.

Download or read book Animal Models of Molecular Pathology written by P. Michael Conn and published by Academic Press. This book was released on 2011-11-26 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores some of the most exciting recent advances in basic research on animal models of molecular pathology. - This series provides a forum for discussion of new discoveries, approaches, and ideas - Contributions from leading scholars and industry experts - Reference guide for researchers involved in molecular biology and related fields

Download or read book Tolerating Factor VIII Novel Strategies to Prevent and Reverse Anti FVIII Inhibitors written by Kathleen P. Pratt and published by Frontiers Media SA. This book was released on 2021-03-05 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The article processing charges (APCs) for some articles in this collection were partly financed by the Henry M. Jackson Foundation for the Advancement of Military Medicine, Maryland, USA (HJF), with funds which were originally granted by Grifols S.A, Barcelona, Spain (Grifols). Neither HJF nor Grifols influenced the content of any article in this collection.