Download or read book Physical Models of Cell Motility written by Igor S. Aranson and published by Springer. This book was released on 2015-12-16 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book surveys the most recent advances in physics-inspired cell movement models. This synergetic, cross-disciplinary effort to increase the fidelity of computational algorithms will lead to a better understanding of the complex biomechanics of cell movement, and stimulate progress in research on related active matter systems, from suspensions of bacteria and synthetic swimmers to cell tissues and cytoskeleton.Cell motility and collective motion are among the most important themes in biology and statistical physics of out-of-equilibrium systems, and crucial for morphogenesis, wound healing, and immune response in eukaryotic organisms. It is also relevant for the development of effective treatment strategies for diseases such as cancer, and for the design of bioactive surfaces for cell sorting and manipulation. Substrate-based cell motility is, however, a very complex process as regulatory pathways and physical force generation mechanisms are intertwined. To understand the interplay between adhesion, force generation and motility, an abundance of computational models have been proposed in recent years, from finite element to immerse interface methods and phase field approaches.This book is primarily written for physicists, mathematical biologists and biomedical engineers working in this rapidly expanding field, and can serve as supplementary reading for advanced graduate courses in biophysics and mathematical biology. The e-book incorporates experimental and computer animations illustrating various aspects of cell movement./div

Download or read book Cell Movements written by Dennis Bray and published by Garland Science. This book was released on 2001 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book vividly describes how complex and integrated movements can arise from the properties and behaviors of biological molecules. It provides a uniquely integrated account in which the latest findings from biophysics and molecular biology are put into the context of living cells. This second edition is updated throughout with recent advances in the field and has a completely revised and redrawn art program. The text is suitable for advanced undergraduates, graduate students, and for professionals wishing for an overview of this field.

Download or read book The Fluid Dynamics of Cell Motility written by Eric Lauga and published by Cambridge University Press. This book was released on 2020-11-05 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pedagogical review of the mathematical modelling in fluid dynamics necessary to understand the motility of most microorganisms on Earth.

Download or read book Cells Molecules and Mechanisms written by Eric Wong and published by Axolotl Academic Publishing. This book was released on 2009 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.

Download or read book Cell Movement written by Magdalena Stolarska and published by Springer. This book was released on 2018-10-21 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a collection of original research articles and review articles that describe novel mathematical modeling techniques and the application of those techniques to models of cell motility in a variety of contexts. The aim is to highlight some of the recent mathematical work geared at understanding the coordination of intracellular processes involved in the movement of cells. This collection will benefit researchers interested in cell motility as well graduate students taking a topics course in this area.

Download or read book Algal Cell Motility written by Michael Melkonian and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Algae exhibit the greatest variety of cell motility phenomena in the living world. These range from the peculiar gliding motility of filamentous blue green algae or cyanobacteria to chloroplast movements and cytoplasmic streaming which are most common in higher plants. In addition, cell motility by eukaryotic flagella is the characteristic mode of cell locomotion in algal flagellates and most reproductive cells of algae. Algae use these cell motility systems mainly to orient themselves or their photosynthetic organelles in a suitable light gradient to optimize growth and reproduction. In consequence most of the motility systems are coupled to photoreceptors and are regulated by signal transduction cascades. Algal cell motility has thus attracted consid erable interest also from non-phycologists and some algal motility systems have become models of research in cell and molecular biology. This book summarizes some of the progress that has been made in recent years in the analysis of cell motility phenomena in the algae. Although complete coverage of the subject was not attempted, the six chapters cover all the major types of cell motility systems and the authors provide in depth reviews of gliding motility, chloroplast movements, cytoplasmic streaming, flagellar beat pat terns, mechanisms of flagellar movement and centrin-mediated cell motility.

Download or read book Cell Motility written by Anne Ridley and published by John Wiley & Sons. This book was released on 2005-04-08 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in molecular and biophysical techniques, particularly fluorescence and live cell imaging, are revolutionizing the study of cell motility. New bioprobes not only reveal simple intracellular localization, but also contain details of post-translational modifications, conformational state and protein-protein interactions. Coupling these insights with complementary advances in genetic and biochemical methods is enabling scientists to understand the processes involved in cell motility - from molecular motors to cell movements in vivo in a range of organisms and cell types. This book features landmark essays that provide an up to date and fascinating account of current research and concepts in cell motility.These cover the roles of molecular motors that drive movement and their interactions with the cytoskeleton as well as membrane dynamics that allow cells to change shape and to move. Cell motility plays a key role in development - there are chapters on the genetics of cell migration, the regulation of contact repulsion in growth cones, and the progression from cell migration to cell-cell adhesion. Cell motility is directional - experts describe the molecules that regulate chemotaxis, allowing cells to migrate along pathways specified by chemical gradients. Finally, cell motility can be perturbed by mutation--metastasis occurs when cells lose their normal intercellular interactions and invade other tissue types. All these processes are regulated by signals from the environment, including other tissues in the body, and the various molecules that transmit and transduce these signals are discussed. This book is a 'must read' for cell biologists working in a variety of fields, from development to wound healing, at all levels - post-doctoral fellows, post-graduate students and lab technicians. It is also stimulating reading for molecular and developmental biologists, biophysicists and biochemists.

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Colonic Motility written by Sushil K. Sarna and published by Biota Publishing. This book was released on 2010-11-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.

Download or read book Cell Dynamics written by M. Tazawa and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Motility of Living Cells written by P. Cappuccinelli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophers through the ages have made the astute observation that life, in its many aspects, appears to be continuously moving. All things in the universe, from the cosmic to the atomic level, exhibit some form of movement. Getting down to earth, the capacity to move is also an essential feature of the biological world. Movement was in fact synonymous with life at the time that Antony van Leeuwenhoek made the first simple microscope (seventeenth century). Using his primitive instrument he observed micro-organisms. which he called 'animalcules', swimming through a drop of water, and therefore he proclaimed that they 'seem to be alive'. We now know that movement in this form is not a prerequisite for life. although it is a crucial aspect in many living organisms. Realizing the general importance of motility in the biological world, this book will try to focus on the motility at a cellular level. Motility at a cellular level can take one of several forms: movement of components within the cell itself or movement of the cell as a whole (cell locomotion).

Download or read book Cell Motility written by Robert Goldman and published by . This book was released on 1976 with total page 1403 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Viscoelasticity and Collective Cell Migration written by Ivana Pajic-Lijakovic and published by Academic Press. This book was released on 2021-01-13 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viscoelasticity and Collective Cell Migration: An Interdisciplinary Perspective Across Levels of Organization focuses on the main viscoelastic parameters formulated based on multiscale constitutive modeling and how to measure these rheological parameters based on existent micro-devices such as micro-rheology and micro-elastography. The book sheds light on inter-relationships across viscoelasticity scales, an essential step for understanding various biomedical processes such as morphogenesis, wound healing and cancers invasion. Cumulative effects of structural changes at subcellular and cellular levels influence viscoelasticity at a supracellular level are also covered, providing valuable insights for biologists, physicists, engineers, students and researchers in the field of developmental biology. As this is a complex multidisciplinary field, perspectives are included from experts in biology, biochemistry, biomedicine, biophysics and biorheology. Readers will gain a deeper understanding of the complex dynamics that represent challenges and the necessity for further development in the field. - Discusses the biological/biochemical mechanisms of collective cell migration - Covers the inter-relation between collective cell migration and viscoelasticity by proposing rheological parameters - Contains critical consideration of various experimental techniques that are suitable to measure these parameters

Download or read book The Fluid Dynamics of Cell Motility written by Eric Lauga and published by Cambridge University Press. This book was released on 2020-11-05 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluid dynamics plays a crucial role in many cellular processes, including the locomotion of cells such as bacteria and spermatozoa. These organisms possess flagella, slender organelles whose time periodic motion in a fluid environment gives rise to motility. Sitting at the intersection of applied mathematics, physics and biology, the fluid dynamics of cell motility is one of the most successful applications of mathematical tools to the understanding of the biological world. Based on courses taught over several years, it details the mathematical modelling necessary to understand cell motility in fluids, covering phenomena ranging from single-cell motion to instabilities in cell populations. Each chapter introduces mathematical models to rationalise experiments, uses physical intuition to interpret mathematical results, highlights the history of the field and discusses notable current research questions. All mathematical derivations are included for students new to the field, and end-of-chapter exercises help consolidate understanding and practise applying the concepts.

Download or read book Cell Movement written by Magdalena Stolarska and published by Springer. This book was released on 2018-11-22 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a collection of original research articles and review articles that describe novel mathematical modeling techniques and the application of those techniques to models of cell motility in a variety of contexts. The aim is to highlight some of the recent mathematical work geared at understanding the coordination of intracellular processes involved in the movement of cells. This collection will benefit researchers interested in cell motility as well graduate students taking a topics course in this area.

Download or read book Cell Motility Factors written by I. Goldberg and published by Birkhäuser. This book was released on 2013-03-09 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Protocol Handbook for Cancer Biology written by Gauri Misra and published by Academic Press. This book was released on 2021-02-12 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protocol Handbook for Cancer Biology brings together a comprehensive collection of the methods used for cancer assessment, diagnostics, and therapeutics. Various protocols are discussed along with alternative strategies, including the advantages and limitations of techniques that have been used in labs globally. These protocols are presented by cancer biology experts based on their real-world experience. The protocols in this book will be a valuable resource for cancer researchers and graduate students, who can utilize the techniques described to conduct research more efficiently and successfully. Presents comprehensive protocols used for cancer assessment, diagnostics, and therapeutics all in one place Encompasses alternative strategies considering the requirements of the end user and taking into consideration diverse research settings Discusses limitations and advantages of each method in experimental design and execution, thus saving time during the research process