Download or read book Cell compartments and intracellular trafficking of lipids and proteins Impact on biomedicine written by Silvana Zanlungo and published by Frontiers Media SA. This book was released on 2022-12-30 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Intracellular Delivery written by Aleš Prokop and published by Springer Science & Business Media. This book was released on 2011-05-26 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book features a special subsection of Nanomedicine, an application of nanotechnology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As a consequence of small scale, nanosystems in most cases are efficiently uptaken by cells and appear to act at the intracellular level. Nanotechnology has the potential to improve diagnosis, treatment and follow-up of diseases, and includes targeted drug delivery and regenerative medicine; it creates new tools and methods that impact significantly upon existing conservative practices. This volume is a collection of authoritative reviews. In the introductory section we define the field (intracellular delivery). Then, the fundamental routes of nanodelivery devices, cellular uptake, types of delivery devices, particularly in terms of localized cellular delivery, both for small drug molecules, macromolecular drugs and genes; at the academic and applied levels, are covered. The following section is dedicated to enhancing delivery via special targeting motifs followed by the introduction of different types of intracellular nanodelivery devices (e.g. a brief description of their chemistry) and ways of producing these different devices. Finally, we put special emphasis on particular disease states and on other biomedical applications, whilst diagnostic and sensing issues are also included. Intracellular delivery / therapy is a highly topical which will stir great interest. Intracellular delivery enables much more efficient drug delivery since the impact (on different organelles and sites) is intracellular as the drug is not supplied externally within the blood stream. There is great potential for targeted delivery with improved localized delivery and efficacy.
Download or read book Cell Growth written by Biba Vikas and published by BoD – Books on Demand. This book was released on 2020-03-04 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on cell growth is the ideal resource for a scientist who wishes to learn more about cell growth topics. It provides information on plant growth hormones, kinetic studies on cell growth, growth of fungal cells and production, cell growth measurement, ion homeostasis response to nutrient deficiency stress in plants, intracellular lipid homeostasis in eukaryotes, and cell-based assays in cancer research. Each topic begins with a summary of the essential facts. Chapters were carefully edited to maintain consistent use of terminology and approach of covering topics in a uniform, systematic format.
Download or read book Effects of Membrane Lipids on Protein Function written by Rutilio A. Fratti and published by Frontiers Media SA. This book was released on 2021-06-30 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Chaperonopathies written by Alberto J.L. Macario and published by Springer Science & Business Media. This book was released on 2013-04-10 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Brief provides a concise review of chaperonopathies, i.e., diseases in which molecular chaperones play an etiologic-pathogenic role. Introductory chapters deal with the chaperoning system and chaperoning teams and networks, HSP-chaperone subpopulations, the locations and functions of chaperones, and chaperone genes in humans. Other chapters present the chaperonopathies in general, including their molecular features and mechanistic classification into by defect, excess, or mistake. Subsequent chapters discuss the chaperonopathies in more detail, focusing on their distinctive characteristics: primary or secondary; quantitative and/or qualitative; structural and hereditary or acquired; genetic polymorphisms; gene dysregulation; age-related; associated with cancer, chronic inflammatory conditions, and autoimmune diseases. The interconnections between the chaperoning and the immune systems in cancer development, chronic inflammation, autoimmunity, and ageing are outlined, which leads to a discussion on the future prospects of chaperonotherapy. The latter may consist of chaperone gene and protein replacement/supplementation in cases of deficiency and of gene or protein blocking when the chaperone actively promotes disease. The last chapter presents the extracellular chaperones and details on how the chaperone Hsp60 is secreted into the extracellular space and, thus, appears in the blood of cancer patients with potential to participate in carcinogenesis and chronic inflammation and autoimmunity. Chaperones as clinically useful biomarkers are mentioned when pertinent. Likewise, guidelines for clinical evaluation of chaperonopathies and for their histopathological and molecular identification are provided throughout. The book also provides extensive bibliography organized by chapter and topic with comments.
Download or read book Nanotoxicology in Nanobiomedicine written by PK Gupta and published by Springer Nature. This book was released on 2023-03-20 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides that knowledge needed to introduce individuals to the most important research and content on nanotoxicology in nanobiomedicine. Nanotechnology is helping to considerably improve, even revolutionize many technology and industry sectors: information technology, homeland security, medicine, transportation, energy, food safety, and environmental science, among many others. There is an urgent need for a general reference textbook that presents the most recent information on the toxicity and its effects in all these sectors, biomedicine in particular. It includes historical information, nanotoxicology by subject area and or disease, sources of nanomaterials, drug delivery systems and more. Scientists, researchers, and students in all fields that use nanotechnology will find this book essential reading.
Download or read book MEDICAL INFORMATICS written by DINESH BHATIA and published by PHI Learning Pvt. Ltd.. This book was released on 2015-01-20 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an up-to-date text that presents a detailed exposition of the concepts of Medical Informatics with a simple and student-friendly approach. The topics are comprehensively described and are supported with illustrations, figures and tables which make it a unique offering for both—the students and the teachers. The author has brought all his teaching and research experience to make this book easy to read and understand. The stress is mainly given on the integration of medical informatics in healthcare management, in the context of Indian scenario. The book emphasizes the role of computers in the area of medical services including nursing, clinical care, dentistry, pharmacy, public health and biomedical research. The main focus in healthcare nowadays is given to create, maintain and manage large and complex electronic information data that can securely gather, store, transfer and make accessible Electronic Health Records (EHRs) and Electronic Medical Records (EMRs). The book, organized in an easy-to-read style is highly informative, and attempts to keep up with the quick pace of changes in this field. The book is primarily designed for the undergraduate and postgraduate students of biomedical engineering and paramedical courses. It will also be of great value to the healthcare professionals.
Download or read book Polymer Nanoparticles for Nanomedicines written by Christine Vauthier and published by Springer. This book was released on 2017-01-07 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.
Download or read book Biomedical Science written by Ian Lyons and published by John Wiley & Sons. This book was released on 2011-11-16 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brand new Lecture Notes title provides the core biomedical science study and revision material that medical students need to know. Matching the common systems-based approach taken by the majority of medical schools, it provides concise, student-led content that is rooted in clinical relevance. The book is filled with learning features such as key definitions and key conditions, and is cross-referenced to develop interdisciplinary awareness. Although designed predominantly for medical students, this new Lecture Notes book is also useful for students of dentistry, pharmacology and nursing. Biomedical Science Lecture Notes provides: A brand new title in the award-winning Lecture Notes series A concise, full colour study and revision guide A 'one-stop-shop' for the biomedical sciences Clinical relevance and cross referencing to develop interdisciplinary skills Learning features such as key definitions to aid understanding
Download or read book Form and Function of Phospholipids written by Gordon Brian Ansell and published by Elsevier Science & Technology. This book was released on 1973 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lipids in Plant and Algae Development written by Yuki Nakamura and published by Springer. This book was released on 2016-03-29 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes recent advances in understanding the functions of plant and algal lipids in photosynthesis, in development and signaling, and in industrial applications. As readers will discover, biochemistry, enzymology and analytical chemistry, as well as gene knock-out studies have all contributed to our rapidly increasing understanding of the functions of lipids. In the past few decades, distinct physical and biochemical properties of specific lipid classes were revealed in plant and algal lipids and the functional aspects of lipids in modulating critical biological processes have been uncovered. These chapters from international authors across relevant research fields highlight the underlying evolutionary context of lipid function in photosynthetic unicellular and multicellular organisms. The book goes on to encompass what lipids can do for industrial applications at a time of fascination with plants and algae in carbon fixation and as sources for production of food, energy and novel chemicals. The developmental context is a part of the fresh and engaging perspective that is presented in this work which graduate students and scientists will find both illuminating and useful.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lipid Mediated Signaling written by Eric J. Murphy and published by CRC Press. This book was released on 2010-03-05 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the highly anticipated update to Lipid Second Messengers (CRC Press, 1999), Lipid-Mediating Signaling is a current and comprehensive overview of research methods used in lipid-mediated signal transduction. Pioneering experts provide a much-needed distillation of a decade's worth of advances in research techniques that are pertinent in understand
Download or read book Dictyostelium A Tractable Cell and Developmental Model in Biomedical Research written by Robert J. Huber and published by Frontiers Media SA. This book was released on 2022-08-16 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Understanding Tuberculosis written by Pere-Joan Cardona and published by BoD – Books on Demand. This book was released on 2012-02-15 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycobacterium tuberculosis is a disease that is transmitted through aerosol. This is the reason why it is estimated that a third of humankind is already infected by Mycobacterium tuberculosis. The vast majority of the infected do not know about their status. Mycobacterium tuberculosis is a silent pathogen, causing no symptomatology at all during the infection. In addition, infected people cannot cause further infections. Unfortunately, an estimated 10 per cent of the infected population has the probability to develop the disease, making it very difficult to eradicate. Once in this stage, the bacilli can be transmitted to other persons and the development of clinical symptoms is very progressive. Therefore the diagnosis, especially the discrimination between infection and disease, is a real challenge. In this book, we present the experience of worldwide specialists on the diagnosis, along with its lights and shadows.
Download or read book Spherical Nucleic Acids written by Chad A. Mirkin and published by CRC Press. This book was released on 2020-09-01 with total page 1806 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spherical nucleic acids (SNAs) comprise a nanoparticle core and a densely packed and highly oriented nucleic acid shell, typically DNA or RNA. They have novel architecture-dependent properties that distinguish them from all other forms of nucleic acids and make them useful in materials synthesis, catalysis, diagnostics, therapeutics, and optics/plasmonics. This book covers over two decades of Dr. Mirkin’s research on SNAs and their anisotropic analogues, including synthesis and fundamental properties, and applications in colloidal crystallization, adaptive matter, and nanomedicine, spanning extra- and intracellular diagnostics, gene regulation, and immunomodulation. It is a reprint volume that compiles 101 key papers from high-impact journals in this research area published by the Mirkin Group at Northwestern University, Illinois, USA, within the International Institute for Nanotechnology, and collaborators. Volume 1 provides an overview and a historical framework of engineering matter from DNA-modified constructs and discusses the enabling features of nucleic acid–functionalized nanomaterials. Volume 2 covers design rules for colloidal crystallization, building blocks for crystal engineering, and DNA and RNA as programmable bonds. Volume 3 discusses colloidal crystallization processes and routes to hierarchical assembly, dynamic nanoparticle superlattices, surface-based and template-confined colloidal crystallization, optics and plasmonics with nanoparticle superlattices, and postsynthetic modification and catalysis with nanoparticle superlattices. Volume 4 covers diagnostic modalities, and intracellular therapeutic and diagnostic schemes based upon nucleic acid–functionalized nanomaterials.
Download or read book Recent Advances in Novel Drug Carrier Systems written by Ali Demir Sezer and published by BoD – Books on Demand. This book was released on 2012-10-31 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.
