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Book Memory Loss  Alzheimer s Disease  and Dementia

Download or read book Memory Loss Alzheimer s Disease and Dementia written by Andrew E. Budson and published by Elsevier Health Sciences. This book was released on 2015-05-20 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now presented in full color, this updated edition of Memory Loss, Alzheimer's Disease, and Dementia is designed as a practical guide for clinicians that delivers the latest treatment approaches and research findings for dementia and related illnesses. Drs. Budson and Solomon — both key leaders in the field — cover the essentials of physical and cognitive examinations and laboratory and imaging studies, giving you the tools you need to consistently make accurate diagnoses in this rapidly growing area. Access in-depth coverage of clinically useful diagnostic tests and the latest treatment approaches. Detailed case studies facilitate the management of both common and uncommon conditions. Comprehensive coverage of hot topics such as chronic traumatic encephalopathy, in addition to new criteria on vascular dementia and vascular cognitive impairment. Includes new National Institute on Aging–Alzheimer's Association and DSM-5 criteria for Alzheimer’s Disease and Mild Cognitive Impairment. Learn how to use new diagnostic tests, such as the amyloid imaging scans florbetapir (Amyvid), flutemetamol (Vizamyl), and florbetaben (Neuraceq), which can display amyloid plaques in the living brains of patients. Updated case studies, many complete with videos illustrating common tests, clinical signs, and diagnostic features, are now incorporated into the main text as clinical vignettes for all major disorders. Brand-new chapters on how to approach the differential diagnosis and on primary progressive aphasia. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

Book Marijuana As Medicine

    Book Details:
  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release : 2000-12-30
  • ISBN : 0309065313
  • Pages : 216 pages

Download or read book Marijuana As Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2000-12-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

Book The Health Effects of Cannabis and Cannabinoids

Download or read book The Health Effects of Cannabis and Cannabinoids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-03-31 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Book Magnesium in the Central Nervous System

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Book Therapeutic Uses of Cannabis

Download or read book Therapeutic Uses of Cannabis written by British Medical Association and published by CRC Press. This book was released on 1997-11-18 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the last Annual Representative Meeting of the British Medical Association a motion was passed that `certain additional cannabinoids should be legalized for wider medicinal use.'' This report supports this landmark statement by reviewing the scientific evidence for the therapeutic use of cannabinoids and sets the agenda for change. It will be welcomed by those who believe that cannabinoids can be used in medical treatment. The report discusses in a clear and readable form the use and adverse effects of the drug for nausea, multiple sclerosis, pain, epilepsy, glaucoma, and asthma.

Book Keep Sharp

    Book Details:
  • Author : Sanjay Gupta
  • Publisher : Simon and Schuster
  • Release : 2021-01-05
  • ISBN : 1501166751
  • Pages : 336 pages

Download or read book Keep Sharp written by Sanjay Gupta and published by Simon and Schuster. This book was released on 2021-01-05 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keep your brain young, healthy, and sharp with this science-driven guide to protecting your mind from decline by neurosurgeon and CNN chief medical correspondent Dr. Sanjay Gupta. Throughout our life, we look for ways to keep our minds sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers “the book all of us need, young and old” (Walter Isaacson, #1 New York Times bestselling author of The Code Breaker) with insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age. Keep Sharp debunks common myths about aging and mental decline, explores whether there’s a “best” diet or exercise regimen for the brain, and explains whether it’s healthier to play video games that test memory and processing speed, or to engage in more social interaction. Discover what we can learn from “super-brained” people who are in their eighties and nineties with no signs of slowing down—and whether there are truly any benefits to drugs, supplements, and vitamins. Dr. Gupta also addresses brain disease, particularly Alzheimer’s, answers all your questions about the signs and symptoms, and shows how to ward against it and stay healthy while caring for a partner in cognitive decline. He likewise provides you with a personalized twelve-week program featuring practical strategies to strengthen your brain every day. Keep Sharp is the “must-read owner’s manual” (Arianna Huffington) you’ll need to keep your brain young and healthy regardless of your age!

Book Cannabis Healing

    Book Details:
  • Author : Franjo Grotenhermen
  • Publisher : Simon and Schuster
  • Release : 2020-09-22
  • ISBN : 1620558327
  • Pages : 290 pages

Download or read book Cannabis Healing written by Franjo Grotenhermen and published by Simon and Schuster. This book was released on 2020-09-22 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everything you need to know to use cannabinoids safely and effectively for better health and healing of a wide range of conditions • Explains the biochemistry of cannabinoids and shows how they interact with the human body • Offers a complete discussion of safe use, possible side effects, contraindications, and precautions, including during pregnancy and chemotherapy • Explores the use of CBD to treat seizures, anxiety, muscular disorders, and psychotic states and the use of THC to treat schizophrenia, Alzheimer’s, ADHD, Tourette’s, Parkinson’s, depression, COPD, and chronic pain, among many other physical, neurological, and emotional conditions In this authoritative yet practical guide to the healing properties of cannabis and cannabinoids such as THC and CBD, Franjo Grotenhermen, M.D., explores how to use these substances to treat a wide range of physical and emotional conditions. Dr. Grotenhermen first examines the history of marijuana as medicine, including its important role in U.S. medical practice during the 19th century. He explains the biochemistry of cannabinoids and shows how they interact with the human body, including a look at cannabinoid receptors and how cannabinoids occur naturally in the body. The author then draws on his years of experience legally treating patients in Germany as well as numerous research studies and tests to provide an in-depth guide to the many healing applications for cannabis and its derivatives. The therapeutic applications covered include the use of CBD to treat seizures, epilepsy, anxiety, several forms of cancer, muscular disorders, and psychotic states and the use of THC to treat schizophrenia, Alzheimer’s, ADHD, Tourette’s, Parkinson’s, impotence, depression, lupus, COPD, and chronic pain, among many other physical, neurological, and emotional conditions. The author examines the various cannabis-derived medications available, such as Cannabinol, Dronabinol, and Marinol, and the main methods of administering cannabis. He offers a complete discussion of safe use, possible side effects, contraindications, and precautions (including during pregnancy and chemotherapy), alongside research data that confirms cannabis as one of the least toxic substances in existence. Written by a practicing physician, this guide provides everything you need to know to use cannabinoids safely and effectively for health and healing.

Book Reader s Digest The Essential Guide to CBD

Download or read book Reader s Digest The Essential Guide to CBD written by Reader's Digest and Project CBD and published by Simon and Schuster. This book was released on 2021-03-23 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Reader’s Digest Essential Guide to CBD is an authoritative but user-friendly primer on CBD. CBD has splashed across the nation’s headlines, taken the country by storm, and has everyone from Coca-Cola to Starbucks considering adding this new “miracle supplement” to their drinks. But the FDA has only approved it for use in treating epilepsy in children. What is CBD, anyway? What’s the difference between CBD, THC, cannabis, hemp, and marijuana? Can CBD help me lose weight? How much CBD do I need to take to help my condition? What do I look for when buying CBD? Is it better to take CBD oil or gummies or what? The Reader’s Digest Guide to CBD will answer all of these questions and much more, including both first-person anecdotes of real people’s experiences with CBD and straightforward reporting about what studies have actually been done and what they show. Written in part by the experts at Project CBD, the book will separate fact from fiction, hype from reality.

Book The CBD Oil Miracle

Download or read book The CBD Oil Miracle written by Laura Lagano and published by Macmillan + ORM. This book was released on 2019-03-26 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improve your health and happiness with a guide to nature's miracle oil Discover all the ways in which cannabidiol, a natural remedy from the cannabis plant, can change your life. The healing properties of this ancient medicine can boost mood, relieve pain, calm inflammation, improve heart health, strengthen bones, promote brain health, balance hormones, regulate the immune system, soothe skin conditions, and contribute to overall wellness in so many ways. The CBD Oil Miracle guides you through the medicinal history and science behind CBD oil and empowers you to: · Determine the dosage and intake form that is right for you and become an informed shopper · Use CBD to alleviate more than 30 common conditions, including Alzheimer’s disease, anxiety, depression, diabetes, insomnia, irritable bowel syndrome, and migraine · Calm an anxious pet and treat many common dog and cat illnesses · Benefit from the anti-aging effects CBD can bring to your beauty and skincare routine · Boost your immune-system, heart, and brain health Expert yet understandable information will help you learn about this compound that is rapidly sparking interest around the globe.

Book The Brain on Cannabis

    Book Details:
  • Author : Rebecca Siegel
  • Publisher : Citadel Press
  • Release : 2021-09-28
  • ISBN : 0806540877
  • Pages : 304 pages

Download or read book The Brain on Cannabis written by Rebecca Siegel and published by Citadel Press. This book was released on 2021-09-28 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 25 years, the renowned Amen Clinics has been a front line resource for brain health . . . NOW theY TACKLE all your questions about how marijuana affects your brain—and the brain of your child. Since marijuana became legal in many states, people of all ages are using it for pain relief and treatment of a variety of illnesses and ailments. But is it safe? In this comprehensive book, renowned psychiatrist and licensed prescriber of medical marijuana Dr. Rebecca Siegel delivers the most complete guide yet about the benefits and risks of using marijuana today. Based on the latest scientific research, this easy-to-read book busts all the myths and helps you navigate the sometimes confusing and often-changing world of marijuana. Within these pages you’ll discover a wealth of invaluable information, including: • Why medical marijuana is vastly different than CBD and recreational marijuana—especially when it comes to children and teenagers • Evidence-based information on how cannabis is being used to treat an array of ailments and conditions • The difference between various marijuana delivery systems, including edibles • Why marijuana-induced psychosis has risen 450% among current pot users, resulting in increases of depression and suicide • How to talk to teens or young adults about recreational marijuana use in a way that brings you closer • How marijuana affects mood, productivity, and overall brain health • Long-term vs. short-term risks for teens, adults, and older adults With a foreword by renowned psychiatrist and brain health expert Dr. Daniel Amen, The Brain on Cannabis reveals everything you ever wanted to know about marijuana so you can make informed decisions for yourself—and your loved ones.

Book Healing With Hemp CBD Oil

Download or read book Healing With Hemp CBD Oil written by Earl Mindell, RPh, MH, PhD and published by Square One Publishers, Inc.. This book was released on 2017-10-17 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: The health benefits of marijuana are now getting a good deal of attention. Yet hemp—a close relative of marijuana—is actually a far richer source of CBD, the compound responsible for effectively treating dozens of disorders, and contains very little THC, the substance responsible for marijuana’s highs. Sounds like growing and using hemp is a win-win situation, right? Not quite, because the US government, which holds the patent for CBD specifically because of its healing abilities, has unfairly classified hemp as a Class 1 drug, thereby banning people in the United States from growing it commercially. If you find this confusing, you’re not alone. That’s why best-selling author Earl Mindell has written Healing with Hemp CBD Oil, a straightforward book that will first help you understand what’s going on with hemp oil in the United States, and then teach you how to use this valuable natural remedy to improve your health. The book begins by looking at the important role the hemp plant has played in both Eastern and Western societies as a source for paper, textiles, rope, and so much more. This is followed by a discussion of the science behind CBD’s medical benefits. The author then provides a consumer’s guide to buying hemp products—especially its oil and its CBD supplements—and offers an eye-opening examination of hemp’s legal status in the United States, from the 1900s to now. Finally, based on up-to-date studies, Dr. Mindell presents an A-to-Z guide to the many uses of hemp oil and CBD for various health conditions, from arthritis to depression to heart disease. Although the United States has given CBD-rich hemp a problematic legal status, fortunately, this product—sourced from other countries—is readily available. Healing with Hemp CBD Oil guides you in using this all-natural substance as a safe, side effect-free remedy.

Book Medicinal Usage of Cannabis and Cannabinoids

Download or read book Medicinal Usage of Cannabis and Cannabinoids written by Victor R Preedy and published by Elsevier. This book was released on 2023-06-02 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Usage of Cannabis and Cannabinoids offers readers a comprehensive reference on the medical usage and symptom relief provided by these compounds in a variety of disorders. With coverage of neurological diseases like Alzheimer's and Parkinson's, and a wide range of other afflictions including depression, anxiety, nausea and cancer, this broad coverage allows readers to learn about symptom control, along with the physiological, psychological and pharmacological effects of these compounds. Unique case reports are provided as well. This volume provides a platform for research on the use of these compounds in improving patient care, brain function and neurological dysfunction. - Summarizes the medicinal usage of cannabis and cannabinoids in a variety of conditions - Contains chapter abstracts, key facts, a dictionary and a summary - Examines symptom control of conditions such as depression, anxiety and sleep - Discusses cannabis usage in Alzheimer's, Parkinson's, Multiple Sclerosis and cancer - Features case reports and chapters on the physiological, psychological and pharmacological effects

Book Recent Advances in Cannabinoid Research

Download or read book Recent Advances in Cannabinoid Research written by Willard James Costain and published by BoD – Books on Demand. This book was released on 2019-05-10 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific interest in cannabinoid research is currently experiencing a significant increase because of changing attitudes toward Cannabis and the evolving awareness of its pharmaceutical benefits. Coincidently, numerous jurisdictions are moving toward legalizing Cannabis and Cannabis-derived products, which reflects a larger global movement to understand Cannabis and its bioactive chemicals for their potential biomedical uses, harms, and economic value. Research activities are surging to fill important knowledge gaps in the field of cannabinoids as they continue to be identified. The purpose of this book is to summarize some leading areas of research in the cannabinoid field where knowledge gaps are actively being addressed. The research described herein spans basic biological and clinical research.

Book CBD OIL The Real Miracle Is Coming

Download or read book CBD OIL The Real Miracle Is Coming written by Sherman Litt and published by Norwalk Publishing LA. This book was released on with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: CBD Oil: Read The Secrets About The Miracle Healing Power of CBD Oil There are two types of people who use CBD oil; those who experience the benefits and can’t wait to tell everyone that they know and those who experience the benefits but keep it to themselves, out of fear of being stigmatized by the people they know. Which side of history will you be on? After years of using CBD Oil, I decided to write a book, try the benefits that come with it, everything explained in my book. CBD oil, or cannabidiol oil, is an extract made from the hemp plant, which is a member of the cannabis family. Many of the stigmas surrounding cannabis oil come from a misunderstanding about the classification of the plant. Yes, cannabis does produce marijuana buds. No, this does not mean that CBD oil will get you high. In fact, CBD oil does not contain enough THC to get you high, which is the psychoactive component found in marijuana. CBD oil offers only the medicinal benefits. There has been a lot of gray area in the past few decades concerning the legality of CBD oil, as well as the ethics that surround keeping it away from people it can truly help. CBD oil can treat everything from seizures to anxiety, helpings hosts of people overcome medical conditions and go onto lead better lives. It even has benefits for the average user, as it works with the endocannabinoid system to promote overall health. We’ll get deeper into what the endocannabinoid system is in the book and how CBD works with it to help promote health. The misinformation stops now. As you read through this book, you will find a brief history on the legality and use of CBD oil over time. You will also learn about what CBD oil is, how it is extracted, and the many benefits. In the final chapter, you’ll find some guidelines about where you can source CBD oil and how you can use it for your condition. If you have ever wished you could lay your hands on proven tips and secrets about the healing power of CBD oil, this is where your search ends! Discover how you can defeat or soothe depression, pain, anxiety, Huntington’s, Alzheimer’s and a host of other sicknesses & diseases by arming yourself with accurate information you’ll be exposed to in this book. CBD Oil: The Real Miracle is Coming aims to inform and clear the misperception about CBD oil and as well provide well-researched answers to questions like: What it is exactly and How It’s Made The History of CBD Oil and its Legality If it is legal, where can I buy? The Miraculous Benefits of CBD Oil Guidelines for Taking CBD And a few other FAQs About CBD Oil I'm very happy to tell you that the informations that have been revealed in this book are based on years of my experience and months of in-depth research for the benefit of both CBD newbies and experienced field veterans. Be informed, be free of pain.

Book Marijuana and the Cannabinoids

    Book Details:
  • Author : Mahmoud A. ElSohly
  • Publisher : Springer Science & Business Media
  • Release : 2007-11-15
  • ISBN : 1592599478
  • Pages : 323 pages

Download or read book Marijuana and the Cannabinoids written by Mahmoud A. ElSohly and published by Springer Science & Business Media. This book was released on 2007-11-15 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although primarily used today as one of the most prevalent illicit leisure drugs, the use of Cannabis sativa L., commonly referred to as marijuana, for medicinal purposes has been reported for more than 5000 years. Marijuana use has been shown to create numerous health problems, and, consequently, the expanding use beyond medical purposes into recreational use (abuse) resulted in control of the drug through international treaties. Much research has been carried out over the past few decades following the identification of the chemical structure of THC in 1964. The purpose of Marijuana and the Cannabinoids is to present in a single volume the comprehensive knowledge and experience of renowned researchers and scientists. Each chapter is written independently by an expert in his/her field of endeavor, ranging from the botany, the constituents, the chemistry and pharmacokinetics, the effects and consequences of illicit use on the human body, to the therapeutic potential of the cannabinoids.

Book Properties of Cannabis Derivatives in Alzheimer s Disease

Download or read book Properties of Cannabis Derivatives in Alzheimer s Disease written by Pharmacology University and published by Pharmacology University. This book was released on 2021-12-07 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease is a medical condition identified by the German psychiatrist Alois Alzheimer in 1901, who described the first case as characterized by the degeneration of the central nervous system. It is a type of dementia, evidenced by progressive atrophy of the brain, resulting from neuronal alteration and death, especially of those neurons located in the cerebral cortex and the hippocampus. The clinical manifestations of the disease vary among patients. Nonetheless, most cases present the following symptoms: amnesia, behavioral disorders, sleep disorders, disorientation, hallucinations, general deterioration of the physical condition, health, and others. Although the histopathological mechanisms, which lead to the death of neurons, have been accurately identified, the underlying cause of the disease remains partly a mystery. The deterioration of the brain tissue is due to a process of cellular toxicity where three elements intervene: accumulation of beta-amyloid peptides, exaggerated phosphorylation of tau proteins leading to cell death, and the production of reactive oxygen species, which condition the damage from free radicals. Epidemiological data from 2015 showed that approximately 46 million people were affected with dementia worldwide, of which 9.4 million were in the Americas, 10.5 million in Europe, 4 million in Africa, and 22.9 million in Asia. It is estimated that by 2035 these figures could double. Given the high numbers projected for the future for Alzheimer's disease, the development of therapeutic alternatives is a must to minimize the adverse effects or reduce the risk of a patient's life suffering from deteriorating brain processes, such as memory and the ability to make decisions, is expected. Nowadays, there are no specific drugs to treat Alzheimer's, so therapeutic approaches are applied to control and manage clinical manifestations, like using nervous system depressants to combat the patients' mood swings and anxiety. It is a concern that many of these drugs cause adverse effects, which further compromise the quality of life of the patient suffering from this disease. But, even more importantly, these drugs are often highly toxic at high doses, with lethal doses not very difficult to achieve, which implies a significant risk in the context of a patient prone to disorientation and frequent memory disorders. Modern scientific research discovered the endocannabinoid system's protective role with neurodegenerative diseases such as Alzheimer's. The elements through which cannabinoids contribute to minimizing the effect it has on neuronal cells, include cellular mechanisms to regulate the exaggerated inflammatory response, a result of the stimulation of beta-amyloid peptide, and the promotion of the synthesis of degradative enzymes of this substance. Endocannabinoid system stimulation through phytocannabinoids use, such as CBD, promotes neurogenesis (formation of new neurons from precursor cells) and triggers protective mechanisms against free-radical damage. Also, Δ9-THC protects the brain from various neuronal aggressions and ameliorates, both symptoms of neurodegeneration. As scientific literature becomes available, the link between the endocannabinoid system and the delay in the progression of neurodegenerative diseases, such as Alzheimer's, is more evident. The same thing happens with other beneficial properties, also attributed to cannabinoids use, such as acting as anxiolytics, antidepressants, neuroprotective, orexigenic, memory stimulants, and regulating sleep. There is great interest in the proposal of medical cannabis as a therapeutic alternative in the management and treatment of Alzheimer's disease. In the future, it could position itself as one of the most effective and safe ways to treat or slow down the degenerative process in this pathology.

Book Medicinal Cannabis and CBD in Mental Healthcare

Download or read book Medicinal Cannabis and CBD in Mental Healthcare written by Kylie O'Brien and published by Springer Nature. This book was released on 2021-10-27 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book functions as a clinician’s guide to the use of cannabidiol (CBD) in the treatment of mental health conditions. It conveys the scientific evidence of efficacy of CBD as well as THC and addresses the social stigma attached to its medical use. The book describes the endocannabinoid system, how stress and the endocannabinoid system interact and key constituents, pharmacokinetics and safety aspects of medicinal cannabis, focusing on CBD and THC. Chapters on specific mental health conditions describe the underpinning pathomechanisms including how the endocannabinoid system is involved, and summarises the scientific evidence including animal and human research for the use of CBD and THC in treatment of such conditions. Topics covered include anxiety, depression, post-traumatic stress disorder, insomnia, Alzheimer's Disease and autism spectrum disorder. Chapters also discuss treatment guidelines and case studies. Unique and focused, Medicinal Cannabis and CBD in Mental Healthcare is an invaluable reference for medical practitioners seeking to adopt CBD-use in their treatment plans.