Download or read book Organic Synthesis with Carbohydrates written by Geert-Jan Boons and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrates offer a ready source of enantiomerically pure starting materials. They have been used for the imaginative synthesis of a wide range of compounds, and have been found to be effective chiral auxiliaries which enable the introduction of a range of functionalities in a highly enantioselective manner. In a subject dominated by volumes at research and professional level, this book provides a broad understanding of the use of carbohydrates in organic synthesis, at postgraduate student level. Emphasis is placed on retrosynthetic analysis, with discussion of why a particular synthetic route has been chosen, and mechanistic explanations are provided for key and novel reactions. Wherever possible, the authors highlight points of general significance to organic synthesis. Selected experimental conditions and reaction details are incorporated to ensure that information can be utilised in research. The book is extensively referenced and so provides a convenient point of entry to the primary literature.
Download or read book Carbohydrates written by Helen Osborn and published by Academic Press. This book was released on 2003-04-22 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows the practising synthetic chemist to choose between all the alternatives and assess their real advantages and limitations. Each chapter in Carbohydrates details a particular theme associated with carbohydrate synthesis. A brief review of the subject area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. In order for the roles of carbohydrates to be thoroughly analysed and assessed, glycobiologists require access to defined target carbohydrates in useful quantities. Thus carbohydrates and glycoconjugates are now recognized as important targets for total synthesis programmes and it is essential to develop efficient regio- and stereoselective methods for the synthesis of carbohydrates. Whilst carbohydrates can sometimes be isolated from natural sources, synthetic strategies often offer the advantage of allowing access to larger quantities of material as well as entry to analogues of the natural carbohydrates. The latest volume in the long standing Best Synthetic Methods series Clear chapter by chapter breakdown of carbohydrate synthesis themes with examples of good practical methods for common carbohydrate syntheses
Download or read book Carbohydrate Synthesis written by Clay S. Bennett and published by American Chemical Society. This book was released on 2023-12-18 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approaching carbohydrate chemistry for the first time can be daunting as basic information is often buried in texts intended for advanced practitioners in the field. This brief primer attempts to bridge that gap. Chapter 1 introduces the basics of carbohydrate structure. Chapter 2 introduces the various roles carbohydrates play in biology. Chapter 3 discusses the glycosylation reaction used to assemble oligosaccharides along with a survey of commonly used glycosyl donors. Chapter 4 discusses commonly used protecting groups. Chapter 5 covers advances in automating the carbohydrate synthesis. Chapter 6 introduces the role of enzymes in the synthesis of homogeneous carbohydrates and glycoproteins. The authors hope this primer will introduce the uninitiated to the challenges and beauty of carbohydrate synthesis and inspire them to bring a new perspective and new advances to the field. Only by doing so will we, as a community of synthetic chemists, be able to tame one of the last and arguably most complex areas of chemical space to create new advances in human health.
Download or read book Synthesis of Carbohydrates Through Biotechnology written by Peng George Wang and published by . This book was released on 2004 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Carbohydrates Through Biotechnology describes rapid developing and cutting-edge new technologies in glycoscience. These new approaches combine advantages of molecular biology, genetic engineering and chemistry, and provide access to synthetic carbohydrates.
Download or read book Modern Methods in Carbohydrate Synthesis written by Shaheer H. Khan and published by CRC Press. This book was released on 2020-08-26 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Methods in Carbohydrate Synthesis presents in one volume a sequence of chapters leading from classical methods through to today's newest state-of -the-art technology for oligosaccharide synthesis. It places particular emphasis on the most recent breakthroughs in the field, including emerging technologies for both oligosaccharide and glycoconjugate synthesis. Chapters describing the synthesis of increasingly important glycosidic linkage analogs, as well as the oligosaccharides containing derivatives and analogs of natural sugars are included. While chemical-synthetic methods constitute the major part of the book, completing the volume is a section on the rapidly expanding and important field of enzymatic synthesis, also covering combined chemical and enzymatic synthesis. Chapters are written by leading experts in the field. Wherever possible, methods of synthesis are provided in sufficient detail to allow the reader to implement the techniques described. More than 1700 references are provided in the 21 chapters comprising the book. This volume should provide a wealth of information to a large number of synthetic organic chemists, medicinal chemists, protein chemists, biochemists, glycobiologists and cell biologists, including students in these fields.
Download or read book Recent Trends in Carbohydrate Chemistry written by Amélia Pilar Rauter and published by Elsevier. This book was released on 2020-05-13 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate chemistry provides access to carbohydrate-based natural products and synthetic molecules as useful biologically active structures relevant to many health care and disease-related biological processes. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates covers green and sustainable reactions, organometallic carbohydrate chemistry, synthesis of glycomimetics, multicomponent reactions, and chemical transformations leading to molecular diversity based on carbohydrates. These include inhibitors of glycogen phosphorylase, which are relevant in controlling type 2 diabetes and sugar sulfates. Polysaccharides, which are commonly modified chemically, are also examined with contributions covering polysaccharide synthesis and modification of polysaccharides to obtain new structures and properties. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates is ideal for researchers working as synthetic organic chemists, and for those interested in biomolecular chemistry, green chemistry, organometallic chemistry, and material chemistry in academia as well as in industry Demonstrates the importance of carbohydrate chemistry as green and sustainable chemistry Details monosaccharide syntheses and transformations toward biologically active small molecular entities Provides the most recent findings on polysaccharide synthesis and bioapplications
Download or read book Synthetic Strategies in Carbohydrate Chemistry written by Vinod Kumar Tiwari and published by Elsevier. This book was released on 2023-11-01 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Strategies in Carbohydrate Chemistry covers carbohydrate synthesis and its widespread application in various disciplines including catalysis. Basic and advanced aspects of carbohydrates are covered, starting with a brief introduction and then followed by protection-deprotection strategies in carbohydrate chemistry, glycosidic bond formation methodology, and their impact in oligosaccharide synthesis. Recent synthetic approaches for O-glycosides, N-glycosides, thioglycosides and C-glycosides, Intramolecular Aglycon Delivery (IAD), and carbohydrate modification are discussed, as well as stereoelectronic factors that control the chemical and biochemical behavior of carbohydrates in living cells. In addition, diverse applications of synthetic carbohydrate chemistry are covered, including sugar-based chiral catalyst in stereoselective synthesis, sugar-based ionic liquids, one-pot tandem reactions in carbohydrates, total synthesis of glycoconjugated natural products, impact of sugar in drug discovery and development, vaccine development, and glycoengineering. This reference is essential reading for researchers working in synthetic carbohydrate chemistry and biochemistry, and will be useful to those working in total synthesis, novel synthetic methodology, catalysis, polymer science, glycobiology, medicinal chemistry, and process development chemistry. Presents a practical and detailed overview on glycosylation methodology Covers automated glycosylation strategies in glycan synthesis Includes recent progress in the synthesis and significance of diverse thio-glycosides, C-glycosides, imino sugars and carbasugars Highlights the impact of enzymes in glycan synthesis Discusses the recent approaches for the synthesis of neoglycoconjugates
Download or read book Modern Synthetic Methods in Carbohydrate Chemistry written by Daniel B. Werz and published by John Wiley & Sons. This book was released on 2013-12-23 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fields of glycochemistry and glycoscience are rich and varied and where much can be learned from Nature. As Nature is not always able to produce carbohydrates in quantities useful for not only in research but also as therapeutic agents, new ways need to be found to optimize the yield. This book presents an overview of the latest developments in the field of carbohydrates, ranging from de-novo approaches via cyclodextrin chemistry to the synthesis of such highly complex glycoconjugates as glycosphingolipids and GPI anchors. The main emphasis remains on the synthetic aspects making the book an excellent source of information for those already involved in carbohydrate chemistry, as well as for those organic chemists who are beginners in this field. Equally of interest to synthetic chemists, as well as medicinal chemists and biochemists.
Download or read book Glycochemical Synthesis written by Shang-Cheng Hung and published by John Wiley & Sons. This book was released on 2016-10-10 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. • Provides detailed discussion on specific topics like oligosaccharide assembly and design of sugars, techniques in glycoconjugate preparation, multivalency, and carbohydrate-based drug design • Uses notable examples, like solution-based one-pot methods and automated methods for sugar assembly, to illustrate important concepts and advances in a rapidly emerging field • Discusses practical applications of carbohydrates, like medicine, therapeutics, drug and vaccine development
Download or read book Enzymes in Carbohydrate Synthesis written by Mark D. Bednarski and published by . This book was released on 1991 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not only assessing the past, present, and future uses of enzymes to synthesize carbohydrates, this volume also illustrates the significance of carbohydrate chemistry and describes how the combination and use of modern enzyme chemistry can advance exploration in the field. Details research at the interface of chemistry and biology for carbohydrate chemistry by demonstrating how to integrate chemical reactions and biological techniques that can be used to synthesize complex bioactive monosaccharides, oligosaccarides, and glycoconjugates. Of particular interest are chapters by George Whitesides and Chi-Huey Wong covering the use of enzymes in monosaccharide synthesis, and Hindsgaul, Thiem, Nilsson, and Whitesides describing the use of activated sugar nucleosides and glycosyltransferases in the synthesis of oligosaccharides and polysaccharides.
Download or read book Carbohydrate Chemistry written by R J Ferrier and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Chemistry provides review coverage of all publications relevant to the chemistry of monosaccharides and oligosaccharides in a given year. The amount of research in this field appearing in the organic chemical literature is increasing because of the enhanced importance of the subject, especially in areas of medicinal chemistry and biology. In no part of the field is this more apparent than in the synthesis of oligosaccharides required by scientists working in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now very well established, for example, by the preparation of specific carbohydrate- based antigens, especially cancer-specific oligosaccharides and glycoconjugates. Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. Each volume of the series brings together references to all published work in given areas of the subject and serves as a comprehensive database for the active research chemist Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
Download or read book Carbohydrate Chemistry written by Christian Vogel and published by CRC Press. This book was released on 2017-09-18 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications—trends that have recently become a serious problem. Featuring contributions from world-renowned experts and overseen by a highly respected series editor, Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 compiles reliable synthetic methods and protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences. Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. The series is unique among other synthetic literature in the carbohydrate field in that, to ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods. The book includes new or more detailed versions of previously published protocols as well as those published in not readily available journals. The essential characteristics of the protocols presented are reliability, updated characterization data for newly synthesized substances and the expectation of wide utility in the carbohydrate field. The protocols presented will be of wide use to a broad range of readers in the carbohydrate field and the life sciences, including undergraduates taking carbohydrate workshops.
Download or read book Carbohydrate Chemistry written by Amelia Pilar Rauter and published by Royal Society of Chemistry. This book was released on 2009-07 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Chemistry provides review coverage of all publications relevant to the chemistry of monosaccharides and oligosaccharides in a given year. The amount of research in this field appearing in the organic chemical literature is increasing because of the enhanced importance of the subject, especially in areas of medicinal chemistry and biology. In no part of the field is this more apparent than in the synthesis of oligosaccharides required by scientists working in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now very well established, for example, by the preparation of specific carbohydrate- based antigens, especially cancer-specific oligosaccharides and glycoconjugates. Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. Each volume of the series brings together references to all published work in given areas of the subject and serves as a comprehensive database for the active research chemist Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
Download or read book Carbohydrates written by Momcilo Miljkovic and published by Springer Science & Business Media. This book was released on 2009-09-18 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: All essential areas of basic synthetic carbohydrate chemistry are covered and appropriately described. In addition, this book explains the basic reaction mechanisms while taking into account modern concepts such as stereoelectronic principles.
Download or read book Carbohydrate Chemistry written by Christian Vogel and published by CRC Press. This book was released on 2017-09-18 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications—trends that have recently become a serious problem. Featuring contributions from world-renowned experts and overseen by a highly respected series editor, Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 compiles reliable synthetic methods and protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences. Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. The series is unique among other synthetic literature in the carbohydrate field in that, to ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods. The book includes new or more detailed versions of previously published protocols as well as those published in not readily available journals. The essential characteristics of the protocols presented are reliability, updated characterization data for newly synthesized substances and the expectation of wide utility in the carbohydrate field. The protocols presented will be of wide use to a broad range of readers in the carbohydrate field and the life sciences, including undergraduates taking carbohydrate workshops.
Download or read book Glycochemical Synthesis written by Shang-Cheng Hung and published by John Wiley & Sons. This book was released on 2016-09-12 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. • Provides detailed discussion on specific topics like oligosaccharide assembly and design of sugars, techniques in glycoconjugate preparation, multivalency, and carbohydrate-based drug design • Uses notable examples, like solution-based one-pot methods and automated methods for sugar assembly, to illustrate important concepts and advances in a rapidly emerging field • Discusses practical applications of carbohydrates, like medicine, therapeutics, drug and vaccine development
Download or read book Modern Methods in Carbohydrate Synthesis written by Shaheer H. Khan and published by . This book was released on 1996 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:
