Download or read book Toxicology of Organophosphate and Carbamate Compounds written by Ramesh C Gupta and published by Academic Press. This book was released on 2011-04-28 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. - Describes everything you need to know about Organophosphates and Carbamates - Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants - Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates - Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases - Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity - Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis - Provides in vitro and in vivo models for neurotoxicity testing - Integrates knowledge of studies in lab animals and humans - Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues - Describes management of Anticholinesterase poisoning in humans

Download or read book Clinical and Experimental Toxicology of Organophosphates and Carbamates written by Bryan Ballantyne and published by Elsevier. This book was released on 2017-01-31 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical & Experimental Toxicology of Organophosphates and Carbamates considers the histochemical localization of cholinesterase in anticholinesterase poisoning. This book is organized into eight parts encompassing 59 chapters that discuss the pharmacology and toxicology of carbamates, as well as the neurobehavioral toxicology of anticholinesterases. Some of the topics covered in the book are the overview of biological and clinical aspects of organophosphates and carbamates; biochemical determination of cholinesterase activity in fluids and tissues; intermediate syndrome in anticholinesterase neurotoxicity; structure-activity relationships and anticholinesterase activity; and the molecular events in delayed neuropathy. Other parts deal with the cardiac effects of anticholinesterase agents and the ecotoxicological consequences of interactions between avian esterases and organophosphorus compounds. These topics are followed by discussions on the analysis of the cutaneous and respiratory tract absorption of anticholinesterases and the use of organophosphorus compounds as chemical warfare agents. The final parts are devoted to the toxicity of anticholinesterases to aquatic organisms. The book can provide useful information to toxicologists, doctors, students, and researchers.

Download or read book The Use and Storage of Methyl Isocyanate MIC at Bayer CropScience written by National Research Council and published by National Academies Press. This book was released on 2012-07-31 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of hazardous chemicals such as methyl isocyanate can be a significant concern to the residents of communities adjacent to chemical facilities, but is often an integral part of the chemical manufacturing process. In order to ensure that chemical manufacturing takes place in a manner that is safe for workers, members of the local community, and the environment, the philosophy of inherently safer processing can be used to identify opportunities to eliminate or reduce the hazards associated with chemical processing. However, the concepts of inherently safer process analysis have not yet been adopted in all chemical manufacturing plants. The Use and Storage of Methyl Isocyanate (MIC) at Bayer CropScience presents a possible framework to help plant managers choose between alternative processing options-considering factors such as environmental impact and product yield as well as safety- to develop a chemical manufacturing system. In 2008, an explosion at the Bayer CropScience chemical production plant in Institute, West Virginia, resulted in the deaths of two employees, a fire within the production unit, and extensive damage to nearby structures. The accident drew renewed attention to the fact that the Bayer facility manufactured and stores methyl isocyanate, or MIC - a volatile, highly toxic chemical used in the production of carbamate pesticides and the agent responsible for thousands of death in Bhopal, India, in 1984. In the Institute accident, debris from the blast hit the shield surrounding a MIC storage tank, and although the container was not damaged, an investigation by the U.S. Chemical Safety and Hazard Investigation Board found that the debris could have struck a relief valve vent pipe and cause the release of MIC to the atmosphere. The Board's investigation also highlighted a number of weaknesses in the Bayer facility's emergency response systems. In light of these concerns, the Board requested the National Research Council convene a committee of independent experts to write a report that examines the use and storage of MIC at the Bayer facility. The Use and Storage of Methyl Isocyanate (MIC) at Bayer CropScience also evaluates the analyses on alternative production methods for MIC and carbamate pesticides preformed by Bayer and the previous owners of the facility.

Download or read book Handbook of Ecotoxicology written by David J. Hoffman and published by CRC Press. This book was released on 2002-11-13 with total page 1316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. Focusing on toxic substance and how they affect the ecosystems worldwide, the book presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. This is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.

Download or read book Carbamates Advances in Research and Application 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbamates—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Phenylcarbamates. The editors have built Carbamates—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Phenylcarbamates in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Carbamates—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book The Science of Carbamates written by Güllü Kaymak and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This scientific book is about the toxic effects of carbamates, which have a functional carbonyl group, and how these effects can be eliminated. It is aimed to provide knowledge to all scientists related to this field. Although carbamates are generally considered to be pesticides, significant amounts of carbamates are used as medicine. This book contains eight chapters that examine carbamates from a variety of perspectives, including the latest research in this field. Chapter One comprehensively studies the chemical structure of carbamates used as drugs and the poisoning of carbamates. Chapter Two discusses how to develop cheap and efficient modes of remediation from the environment. Chapter Three highlights the important role of microorganisms in the degradation of carbamates. Chapter Four focuses on especially biodeterioration of carbamates by fungi. Chapter Five examines the probiotic microorganisms as detoxification tools in the degradation and transformation of carbamates. Chapter Six reviews the genetic risk that may occur as a result of exposure to carbamate pesticides in living things. Chapter Seven explains the genetic biomarkers that help determine the management of chronic pesticide toxicity by determining different gene polymorphisms in agricultural workers as a result of long-term contact with carbamates. Chapter Eight thoroughly studies the clinical information about intoxication that may arise as a result of carbamate group exposure.

Download or read book Chemical Analysis of Non antimicrobial Veterinary Drug Residues in Food written by Jack F. Kay and published by John Wiley & Sons. This book was released on 2016-11-14 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a single-source reference for readers interested in the development of analytical methods for analyzing non-antimicrobial veterinary drug residues in food Provides a comprehensive set of information in the area of consumer food safety and international trade Covers general issues related to analytical quality control and quality assurance, measurement uncertainty, screening and confirmatory methods Details many techniques including nanotechnology and aptamer based assays covering current and potential applications for non-antimicrobial veterinary drugs Provides guidance for analysis of banned drugs including natural and synthetic steroids, Resorcylic acid lactones, and Beta-agonists

Download or read book Carbamate Insecticides written by Ronald J. Kuhr and published by . This book was released on 1976 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development and use; Chemistry and synthesis; Mode of action; Structure-activity relationnships; Toxicology; Metabolic reactions metabolismo; Biological and environmental stability; Residue methodology; Resistance and synergismo.

Download or read book Metabolic Pathways of Agrochemicals written by Terry R Roberts and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.

Download or read book Carbon Dioxide as Chemical Feedstock written by Michele Aresta and published by John Wiley & Sons. This book was released on 2010-01-26 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling the need for an up-to-date handbook, this ready reference closely investigates the use of CO2 for ureas, enzymes, carbamates, and isocyanates, as well as its use as a solvent, in electrochemistry, biomass utilization and much more. Edited by an internationally renowned and experienced researcher, this is a comprehensive source for every synthetic chemist in academia and industry.

Download or read book Handbook of Toxicology of Chemical Warfare Agents written by Ramesh C Gupta and published by Academic Press. This book was released on 2009-04-02 with total page 1182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book.This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security. - Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves researchers time in quickly accessing the very latest definitive details on toxicity of specific agents used in chemical warfare as opposed to searching through thousands of journal articles. Will include the most agent-specific information on the market - Includes detailed coverage of the most exhaustive list of agents possibly used as chemical warfare agents in one source. Section 4: Agents That Can Be Used as Weapons of Mass Destruction ? 25 chapters long. Other books on the market only include a sample selection of specific agents. Offering all possible agents detailed under one cover makes this appealing to a wider audience and saves researchers time - The Forward will be written by Dr. Tetsuo Satoh, Chiba University, Japan. He is one of the most respected, recognizable authorities on chemical warfare agents which will set the authoritative tone for the book - Covers risk to humans, animals and the environment equally. Researchers involved in assessing the risks involved with a possible chemical warfare attack and those who are developing response plans to such attacks must look at not only the risks to human health but to our wildlife and environment as well. The holistic approach taken in this book ensures that the researchers have ready access to the details no matter which aspect of the effects of CWA's they might be concerned with

Download or read book Carbamates Advances in Research and Application 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbamates: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Carbamates in a concise format. The editors have built Carbamates: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Carbamates in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Carbamates: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Recognition and Management of Pesticide Poisonings 5th Ed written by J. Routt Reigart and published by DIANE Publishing. This book was released on 2009-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 5th ed. is an update and expansion of the 1989 4th ed. This EPA manual provides health professionals with information on the health hazards of pesticides currently in use, and current consensus recommendations for management of poisonings and injuries caused by them. As with previous updates, this new ed. incorporates new pesticide products that are not necessarily widely known among health professionals. Contents: (1) General Information: Introduction; General Principles in the Management of Acute Pesticide Poisonings; Environmental and Occupational History; (2) Insecticides; (3) Herbicides; (4) Other Pesticides; (5) Index of Signs and Symptoms; Index of Pesticide Products. Charts and tables.

Download or read book Metabolism of Carbamate Insecticides written by H. W. Dorough and published by . This book was released on 1977 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Liquid Chromatography of Carbamate Pesticides written by Alfred D. Thruston and published by . This book was released on 1972 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biophysics and Physiology of Carbon Dioxide written by C. Bauer and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers presented at the symposium on Biophysics and Physiology of Carbon Dioxide held at Regensburg, April 17-20, 1979. The manuscripts represent the full or even an extended account of the oral presentations. We have decided not to include any part of the discussions which took place after the lectures because this would have led to an undue enlargement of the already substantial volume. The symposium brought together some 60 scientists of various disciplines including biophysicists, chemists, biochemists, physiologists, pharmacologists, as well as clinicians whose research activities are cen tered around the various aspects of the reactions and the regulatory role of CO within the body. 2 In view of the fact that numerous textbooks and Proceedings of Symposia deal expertly with the role of CO in acid-base balance, it 2 was decided not to include this aspect in the present symposium. This holds also for the biochemistry of carboxylation and decarboxylation reactions. Particular emphasis was placed on the following subjects: (1) Chemical reactions of CO in water and facilitated diffusion of CO2 , 2 (2) CO adducts to proteins, in particular hemoglobin, and peptide 2 hormones, (3) structure and function of carbonic anhydrase, (4) CO 2 exchange and carbonic anhydrase activity in respiratory and nonrespi ratory systems. Each section contains at least one introductory paper that presents the current knowledge in a more general framework.

Download or read book Hayes Handbook of Pesticide Toxicology written by and published by Academic Press. This book was released on 2010-02-15 with total page 2407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book's tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. - Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. - Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions - All major classes of pesticide considered - Different routes of exposure critically evaluated