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Book Brain Networks for Studying Healthy and Pathological Aging Mechanisms and Intervention Efficacy

Download or read book Brain Networks for Studying Healthy and Pathological Aging Mechanisms and Intervention Efficacy written by Christos Frantzidis and published by Frontiers Media SA. This book was released on 2020-11-18 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Previous studies showed that both healthy and pathological aging are associated with changes in brain structure and function of the mature human brain. The most prominent anatomical alteration are changes in prefrontal cortex morphology, volume loss and reduced white-matter integrity and hippocampal atrophy. Cognitive decline affects mainly the performance of episodic memory, speed of sensory information processing, working memory, inhibitory function and long-term memory. It has been also proposed that due to the aforementioned changes the aging brain engages in compensatory brain mechanism such as a broader activation of cortical regions (mainly frontal) rather than specialized activation. Evidence suggests that similar changes occur with pathological aging but to a greater extent. In this case information flow is disrupted due to neurodegeneration, functional activation of posterior (occipito-temporal) regions is decreased and as a consequence the brain fails to process sensorial input in the ventral pathway and cognitive deficits appear. In the last years, functional alterations associated with aging have been studied using the mathematical notion of graph theory that offers an integrative approach since it examines different properties of the brain network: 1) Organization level 2) amount of local information processing, 3) information flow 4) cortical community structure and 5) identification of functional / anatomical hubs. So, graph theory offers an attractive way to model brain networks organization and to quantify their pathological deviations. Previous studies have already employed this mathematical notion and demonstrated that age-related neurodegeneration is often accompanied by loss of optimal network organization either due to diminished local information processing or due to progressive isolation of distant brain regions. They have also found that changes in network properties may be present even in the preclinical phase, which could be taken as a biological marker of disease.

Book Cognitive and Brain Aging  Interventions to Promote Well Being in Old Age  Roadmap for Interventions Preventing Cognitive Aging

Download or read book Cognitive and Brain Aging Interventions to Promote Well Being in Old Age Roadmap for Interventions Preventing Cognitive Aging written by Pamela M. Greenwood and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of cognitive aging has evolved from a focus on cataloging age-related declines of brain and mind in healthy older people to a focus on interventions aimed at limiting those declines. Intervention research has obtained convincing evidence of the cognitive benefits of aerobic exercise and working memory training. Recently interest has broadened to include interventions that consider the social and physical environment of the aged individual. Examples of this are investigations of training cognitive-motor integration, interventions to reduce loneliness, mindfulness training, and human factors-based approaches to cognitive deficits. Such approaches move beyond targeting specific abilities in isolation to consider more broadly the overall well-being of the healthy older person. In this Research Topic we call for both empirical and review papers that consider interventions aimed at reducing cognitive and brain aging but also approaches that consider older individuals (animal and human) in their physical and social environment.

Book Cognitive Aging

    Book Details:
  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release : 2015-07-21
  • ISBN : 0309368650
  • Pages : 330 pages

Download or read book Cognitive Aging written by Institute of Medicine and published by National Academies Press. This book was released on 2015-07-21 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: For most Americans, staying "mentally sharp" as they age is a very high priority. Declines in memory and decision-making abilities may trigger fears of Alzheimer's disease or other neurodegenerative diseases. However, cognitive aging is a natural process that can have both positive and negative effects on cognitive function in older adults - effects that vary widely among individuals. At this point in time, when the older population is rapidly growing in the United States and across the globe, it is important to examine what is known about cognitive aging and to identify and promote actions that individuals, organizations, communities, and society can take to help older adults maintain and improve their cognitive health. Cognitive Aging assesses the public health dimensions of cognitive aging with an emphasis on definitions and terminology, epidemiology and surveillance, prevention and intervention, education of health professionals, and public awareness and education. This report makes specific recommendations for individuals to reduce the risks of cognitive decline with aging. Aging is inevitable, but there are actions that can be taken by individuals, families, communities, and society that may help to prevent or ameliorate the impact of aging on the brain, understand more about its impact, and help older adults live more fully and independent lives. Cognitive aging is not just an individual or a family or a health care system challenge. It is an issue that affects the fabric of society and requires actions by many and varied stakeholders. Cognitive Aging offers clear steps that individuals, families, communities, health care providers and systems, financial organizations, community groups, public health agencies, and others can take to promote cognitive health and to help older adults live fuller and more independent lives. Ultimately, this report calls for a societal commitment to cognitive aging as a public health issue that requires prompt action across many sectors.

Book The Aging Mind

    Book Details:
  • Author : National Research Council
  • Publisher : National Academies Press
  • Release : 2000-04-18
  • ISBN : 0309172195
  • Pages : 285 pages

Download or read book The Aging Mind written by National Research Council and published by National Academies Press. This book was released on 2000-04-18 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer's disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.

Book The Cambridge Handbook of Cognitive Aging

Download or read book The Cambridge Handbook of Cognitive Aging written by Ayanna K. Thomas and published by Cambridge University Press. This book was released on 2020-05-28 with total page 1019 pages. Available in PDF, EPUB and Kindle. Book excerpt: Decades of research have demonstrated that normal aging is accompanied by cognitive change. Much of this change has been conceptualized as a decline in function. However, age-related changes are not universal, and decrements in older adult performance may be moderated by experience, genetics, and environmental factors. Cognitive aging research to date has also largely emphasized biological changes in the brain, with less evaluation of the range of external contributors to behavioral manifestations of age-related decrements in performance. This handbook provides a comprehensive overview of cutting-edge cognitive aging research through the lens of a life course perspective that takes into account both behavioral and neural changes. Focusing on the fundamental principles that characterize a life course approach - genetics, early life experiences, motivation, emotion, social contexts, and lifestyle interventions - this handbook is an essential resource for researchers in cognition, aging, and gerontology.

Book Preventing Cognitive Decline and Dementia

Download or read book Preventing Cognitive Decline and Dementia written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-05 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.

Book Music and the Aging Brain

Download or read book Music and the Aging Brain written by Lola Cuddy and published by Academic Press. This book was released on 2020-05-28 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Music and the Aging Brain describes brain functioning in aging and addresses the power of music to protect the brain from loss of function and how to cope with the ravages of brain diseases that accompany aging. By studying the power of music in aging through the lens of neuroscience, behavioral, and clinical science, the book explains brain organization and function. Written for those researching the brain and aging, the book provides solid examples of research fundamentals, including rigorous standards for sample selection, control groups, description of intervention activities, measures of health outcomes, statistical methods, and logically stated conclusions. Summarizes brain structures supporting music perception and cognition Examines and explains music as neuroprotective in normal aging Addresses the association of hearing loss to dementia Promotes a neurological approach for research in music as therapy Proposes questions for future research in music and aging

Book Cognitive Neuroscience of Aging

Download or read book Cognitive Neuroscience of Aging written by Roberto Cabeza and published by Oxford University Press. This book was released on 2017 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: A rapidly growing body of research has consituted a new discipline that may be called cognitive neuroscience of aging. This book offers an introduction to the topic, useful to both professionals & students in cognitive neuroscience, cognitive psychology, neuroscience, neuropsychology & neurology.

Book Brain Aging

    Book Details:
  • Author : David R. Riddle
  • Publisher : CRC Press
  • Release : 2007-04-19
  • ISBN : 9781420005523
  • Pages : 408 pages

Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Book Disease Control Priorities  Third Edition  Volume 8

Download or read book Disease Control Priorities Third Edition Volume 8 written by Donald A. P. Bundy and published by World Bank Publications. This book was released on 2017-11-20 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: More children born today will survive to adulthood than at any time in history. It is now time to emphasize health and development in middle childhood and adolescence--developmental phases that are critical to health in adulthood and the next generation. Child and Adolescent Health and Development explores the benefits that accrue from sustained and targeted interventions across the first two decades of life. The volume outlines the investment case for effective, costed, and scalable interventions for low-resource settings, emphasizing the cross-sectoral role of education. This evidence base can guide policy makers in prioritizing actions to promote survival, health, cognition, and physical growth throughout childhood and adolescence.

Book Modifiable Risk Factors of Accelerated Brain Aging and Dementia

Download or read book Modifiable Risk Factors of Accelerated Brain Aging and Dementia written by Frauke Beyer and published by Frontiers Media SA. This book was released on 2022-06-29 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Clinical Neurology of Aging

    Book Details:
  • Author : Martin Albert, MD, PhD, FAAN
  • Publisher : Oxford University Press
  • Release : 2011-01-11
  • ISBN : 0199708967
  • Pages : pages

Download or read book Clinical Neurology of Aging written by Martin Albert, MD, PhD, FAAN and published by Oxford University Press. This book was released on 2011-01-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neurology of Aging, Third Edition continues the tradition of the First (1984) and Second (1994) editions with 60 chapters written by the world's elite clinicians from neurology, geriatrics and research on all aspects of geriatric neurology. Aging does not automatically imply decline. Many older people find joy in their friendships and their willingness to look at the world with a calmer view than they may have had in youth. This clinically focused book is designed to help clinicians help older persons maintain that joy. Now divided into 9 comprehensive sections, the Third Edition contains subjects ranging from geriatric assessment to pain management and palliative care. Specific sections include: Introduction to Geriatric Neurology; Neurological Assessment in Aging; Cognitive Disorders in Aging; Motor Disorders in Aging; Neuropsychiatric Illness in Aging; Sensory Disturbance in Aging; Peripheral Neurology of Aging; Disease States in Elderly; and Neurological Therapeutics. With a deft touch, the editors - Drs. Martin Albert and Janice Knoefel - have incorporated the geriatric care perspective and a quality-oriented approach to health care throughout the volume. The result: the definitive reference, useful for all clinicians caring for older people and informative to those who set policies that affect research and clinical practice.

Book Physical Activity and the Aging Brain

Download or read book Physical Activity and the Aging Brain written by Ronald Ross Watson and published by Academic Press. This book was released on 2016-12-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Activity and the Aging Brain: Effects of Exercise on Neurological Function is a complete guide to the manifold effects of exercise and physical activity on the aging brain. Cognitive decline and motor impairment, onset of diseases and disorders, and even changes in family structure and social settings that occur as we age can all impact activity levels, yet continued physical activity is crucial for successful neurological functioning. This book examines the role that exercise and physical activity play in halting or modulating the deleterious effects of these numerous aging concerns by first examining the current state of research into how exercise manifests physical changes in the brain. It then discuss how physical activity combines with other lifestyle factors to benefit the aging brain, including nutrition, computerized brain training, and social engagement. Most significantly, it also covers how physical activity can serve as therapy to help alleviate the symptoms of various neurological diseases impacting aging populations, with particular emphasis on Alzheimer’s disease and age-related cognitive decline. The book provides broad coverage of the effects of exercise and physical activity on the aging brain, its therapeutic effects, and the many factors that influence the aging process. Presents research scientists with a complete understanding of the role of exercise in healthy brain aging Considers the roles of nutrition, the mind-body connection, and other lifestyle factors Presents a major resource for exercise and physical activity in the neurological health of older adults Provides a synopsis of key ideas associated with the many aspects of physical activity, along with lifestyle factors that can modify neurological diseases and age-related neurological decline

Book Cognitive Changes of the Aging Brain

Download or read book Cognitive Changes of the Aging Brain written by Kenneth M. Heilman and published by Cambridge University Press. This book was released on 2019-12-05 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the alterations of cognition, perception, and behavior that occur with healthy brain aging, their mechanisms, and their management.

Book Future Directions for the Demography of Aging

Download or read book Future Directions for the Demography of Aging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-07-21 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost 25 years have passed since the Demography of Aging (1994) was published by the National Research Council. Future Directions for the Demography of Aging is, in many ways, the successor to that original volume. The Division of Behavioral and Social Research at the National Institute on Aging (NIA) asked the National Academies of Sciences, Engineering, and Medicine to produce an authoritative guide to new directions in demography of aging. The papers published in this report were originally presented and discussed at a public workshop held in Washington, D.C., August 17-18, 2017. The workshop discussion made evident that major new advances had been made in the last two decades, but also that new trends and research directions have emerged that call for innovative conceptual, design, and measurement approaches. The report reviews these recent trends and also discusses future directions for research on a range of topics that are central to current research in the demography of aging. Looking back over the past two decades of demography of aging research shows remarkable advances in our understanding of the health and well-being of the older population. Equally exciting is that this report sets the stage for the next two decades of innovative researchâ€"a period of rapid growth in the older American population.

Book Clinical Neurology of Aging

Download or read book Clinical Neurology of Aging written by Martin L. Albert and published by Oxford University Press. This book was released on 2011-03-03 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: This clinically focused book is designed to help clinicians help older persons maintain that joy. Now divided into 9 comprehensive sections, this edition contains subjects ranging from geriatric assessment to pain management and palliative care.

Book Non Pharmacological Interventions in Healthy and Pathological Aging  Facts and Perspectives

Download or read book Non Pharmacological Interventions in Healthy and Pathological Aging Facts and Perspectives written by Danúbia Da Cunha De Sá Caputo and published by Frontiers Media SA. This book was released on 2023-05-12 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: