Download or read book Brain Metastases written by Jeffrey Raizer and published by Springer Science & Business Media. This book was released on 2007-10-03 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.

Download or read book Central Nervous System Metastases written by Rohan Ramakrishna and published by Springer Nature. This book was released on 2020-05-27 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a multi-specialty book on the diagnosis, evaluation, and treatment of CNS metastases of the brain and spine. Written by renowned experts in their fields, the book covers essential contemporary topics in CNS metastases care. The book is divided into seven parts that begin with chapters that cover the fundamental biology of disease so that subsequent chapters on imaging, diagnosis, treatment, and palliation can be properly contextualized. This text also provides a framework for understanding the biology of radiation therapy so that radiation treatment options of the brain and spine can be more fully understood. New medications and technologies are reviewed from the perspective of maximizing efficacy and minimizing toxicity, independently and as combinatorial therapy. Central Nervous System Metastases: Diagnosis and Treatment serves as a practical reference for health care providers and trainees. It provides the comprehensive, detailed perspective required to provide holistic care to patients with metastatic disease to the brain and spine.

Download or read book Central Nervous System Metastases written by Manmeet Ahluwalia and published by Springer Nature. This book was released on 2019-11-05 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.

Download or read book Brain Metastases from Primary Tumors Volume 3 written by M. A. Hayat and published by Academic Press. This book was released on 2016-04-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Metastases from Primary Tumors Volume Three: Epidemiology, Biology, and Therapy of Melanoma and Other Cancers provides a comprehensive overview of the metastasis of cancer, the main cause of approximately 90% of cancer associated deaths, yet the mechanisms governing this clinically important process remain poorly understood. Melanoma is the third most common diagnosis among patients with brain metastases, after lung and breast cancer. Approximately 75% of patients with metastatic melanoma develop brain metastases during the course of their disease. Although tumorigenesis of melanoma remains poorly understood, recent advances in gene expression profiling have revealed molecular mechanisms of this deadly disease. In addition, high-throughput gene expression has many advantages over techniques in cancer transcriptomic studies and has led to the discovery of numerous diagnostic, prognostic, and therapeutic targets, which are also detailed in this book. The book discusses the link between primary tumors and brain metastasis of melanoma, including molecular mechanisms, treatment options, prognosis, and general applications. Comprehensive chapters discuss systemic therapy, integrin inhibitors, stereotaxic radiosurgery, and more, making this book a great resource for neurooncologists, neurosurgeons, neurologists, and cancer researchers.

Download or read book Metastatic Cancer Clinical and Biological Perspectives written by Rahul Jandial and published by CRC Press. This book was released on 2013-08-08 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.

Download or read book Brain Tumor Imaging written by Elke Hattingen and published by Springer. This book was released on 2015-09-02 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.

Download or read book Brain Metastases from Primary Tumors Volume 1 written by M. A. Hayat and published by Academic Press. This book was released on 2014-04-03 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection. The only comprehensive reference detailing the link between primary cancers and brain metastases Aids the target audience in determining the incidence of brain metastases in patients with a primary cancer Provided education about the potential use of biomarkers for early detection, diagnosis and prevention of the spread of primary cancer to the brain Documents temporal and gender-related trends in brain metastases from other cancers Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Download or read book Introduction to Cancer Metastasis written by Aamir Ahmad and published by Academic Press. This book was released on 2016-11-14 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Cancer Metastasis provides, in one place, an overview of organ-specific cancer metastasis and the most common sites of cancer metastasis. Through specific chapters on individual primary cancers, their metastasis, and chapters on common metastatic sites, this volume comprehensively informs readers about the broader knowledge base in cancer metastasis. The process of metastasis is particularly responsible for making cancer so lethal. This volume explores both metastasis from sites of origin and common metastatic sites, thus increasing understanding of both perspectives. Includes basic biology and translational approaches to organ-specific cancer sites Provides readers with information on emerging therapeutic targets for cancer metastasis Contains contributions from leading researchers around the globe

Download or read book Brain Metastasis written by L. Weiss and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of those people dying with cancer, many die as a result of metastases. In spite of this, a surprisingly small number of texts have been devoted to this clinically important topic. The present series of monographs originated in discussions, which convinced us of the need for texts on metasasis which would contain not only basic and clinical observations on human beings and where neces sary, on experimental animals but also discussions of the state of the art in diagnosis and therapy. In order to achieve this in-depth approach, for which publication was preceded by small workshops, it was necessary to impose limitations on the scope of the topic. Metastasis is therefore dis cussed by site, and the series is organized accordingly. The first volume in the series, Pulmonary Metastasis, was an expanded version of a Workshop held at Roswell Park Memorial Institute in 1977. This, the second volume, is based on a similar workshop on metastasis to the brain, held at the Memorial Sloan-Kettering Cancer Center in September, 1978. In organiz ing both the workshop and in editing this volume, we have been excep tionally fortunate to receive the generous cooperation of Dr. Jerome B. Posner, a practicing neurologic oncologist who has given freely of his ex pertise in this specialized field.

Download or read book Brain Metastases from Primary Tumors Volume 3 written by M. A. Hayat and published by Academic Press. This book was released on 2016-04-07 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Metastases from Primary Tumors Volume Three: Epidemiology, Biology, and Therapy of Melanoma and Other Cancers provides a comprehensive overview of the metastasis of cancer, the main cause of approximately 90% of cancer associated deaths, yet the mechanisms governing this clinically important process remain poorly understood. Melanoma is the third most common diagnosis among patients with brain metastases, after lung and breast cancer. Approximately 75% of patients with metastatic melanoma develop brain metastases during the course of their disease. Although tumorigenesis of melanoma remains poorly understood, recent advances in gene expression profiling have revealed molecular mechanisms of this deadly disease. In addition, high-throughput gene expression has many advantages over techniques in cancer transcriptomic studies and has led to the discovery of numerous diagnostic, prognostic, and therapeutic targets, which are also detailed in this book. The book discusses the link between primary tumors and brain metastasis of melanoma, including molecular mechanisms, treatment options, prognosis, and general applications. Comprehensive chapters discuss systemic therapy, integrin inhibitors, stereotaxic radiosurgery, and more, making this book a great resource for neurooncologists, neurosurgeons, neurologists, and cancer researchers. Presents the only comprehensive reference detailing the link between primary cancers and brain metastases in melanoma Aids the target audience in discussing various treatment options for patients with brain metastases from melanoma Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Download or read book Brain Metastases written by Jeffrey J. Raizer and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.

Download or read book Intracranial and Spinal Radiotherapy written by Lia M. Halasz and published by Springer Nature. This book was released on 2021-03-08 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical, up-to-date guide to the treatment of patients with brain and spinal tumors. Leading experts in the field explain treatment techniques in detail, highlighting key considerations in the use of external beam radiation therapy, intensity-modulated radiation therapy, particle therapy, radiosurgery, and stereotactic body radiation therapy. Specific recommendations are described for different tumor types, and helpful information provided on other important issues, such as the interaction of radiotherapy and systemic therapy and the avoidance of treatment complications. With the development of modern technology, highly conformal radiotherapy techniques have become more complicated, yet also more widely employed. This book will equip readers with the knowledge required to set up practices to deliver quality brain and spinal radiation therapy appropriate to each patient. It will be of benefit to radiation oncologists, clinical oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses as well as medical oncologists and surgical oncologists with an interest in radiotherapy.

Download or read book Metastatic Disease of the Nervous System written by David Schiff and published by Elsevier. This book was released on 2018-01-04 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail. Covers all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy Presents a multidisciplinary review of the evidence regarding accuracy of diagnostic testing and evidence-based reviews of therapies Addresses metastatic diseases of the nervous system for residents, fellows and clinicians in neurology and oncology

Download or read book Brain Metastasis written by Lawrence R. Kleinberg, MD and published by Demos Medical Publishing. This book was released on 2008-08-19 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: New therapies and treatments targeted at brain metastasis are rapidly resulting in improved survival and quality of life for patients with this condition. Brain Metastasis: A Multidisciplinary Approach conveys vital information about management strategies, outcomes, and techniques to enable oncologists to provide a full range of appropriate care and counseling to patients with metastatic spread to the brain. Faithful to its title, this text espouses a truly multidisciplinary approach, integrating information from the fields of oncology, neurosurgery, radiation oncology, and neurology. Experts in each specialty have gathered that information which is most important for all physicians caring for patients with brain metastasis. Brain Metastasis includes complete discussions for all situations in which radiosurgery might be recommended, including for the treatment of gross brain metastasis; for the prevention of tumor-related injury of brain function; and as an alternative to whole-brain radiotherapy. Features of this uniquely accessible guide include: A timely discussion of exciting recent developments in aggressive care An emphasis on quality-of-life issues and palliative care Special chapters on radiosurgery for both brain metastasis and spinal tumors Full color insert of high-quality images This concise and comprehensive text provides a multidisciplinary information source for brain metastasis. It is an essential resource for any practitioner who cares for patients with this devastating yet surprisingly common condition.

Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Download or read book Current and Future Management of Brain Metastasis written by Dong Gyu Kim and published by Karger Medical and Scientific Publishers. This book was released on 2012-01-01 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Latest guidelines for disease control of brain metastasis Recent strategies combining multiple modalities have opened up a whole new field of brain metastasis management focusing on disease control. The management of brain metastasis in modern times is no longer confined to palliation but seeks preservation of life quality and not only prolonged survival. Up-to-date guidelines and the main aspects of brain metastasis management as well as practical points on how to deal with difficult situations in daily clinical practice are presented. Epidemiology and biology and various effective treatment methods such as surgery, radiosurgery, radiation therapy and chemotherapy are well explained. Each chapter encompasses extensive reviews and presents broad perspectives on specific topics by the most renowned personages who have continuously shown their excellence in this rapidly progressing field. This book contains the most current information on the understanding of brain metastasis management. It is valuable reading for neurosurgeons, neuro-oncologists and radiation oncologists who are searching for the best all-round treatment for their patients.

Download or read book Atlas of Clinical Cases on Brain Tumor Imaging written by Yelda Özsunar and published by Springer Nature. This book was released on 2020-04-28 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents and analyzes clinical cases of brain tumors and follows the classification provided by the WHO in 2016. After introductory chapters reviewing the international literature on the topic, the advances made in all imaging modalities (especially Magnetic Resonance and Computed Tomography) are examined.All radiological findings are supplemented with a wealth of images and brief explanations. The clinical information is given as part of the case discussion, as are the characteristics and differential diagnosis of the tumors. Radiologic-pathologic correlations round out the description of each clinical case.Intended as a quick and illustrative reference guide for radiology residents and medical students, this atlas represents the most up-to-date, practice-oriented reference book in the field of Brain Tumor Imaging.