Download or read book Biomarkers in Leishmaniasis written by Javier Moreno and published by Frontiers Media SA. This book was released on 2020-01-15 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathogenesis Treatment and Prevention of Leishmaniasis written by Mukesh Samant and published by Academic Press. This book was released on 2021-08-18 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment Discusses novel approaches to study parasite infection and treatment Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies
Download or read book Biomarker written by Ghousia Begum and published by BoD – Books on Demand. This book was released on 2018-09-05 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of disease prognosis. Chapters in Part I focus on biomarkers for cancer, including breast cancer and pancreatic cancer, as well as circulating microRNA profiling in cancer biomarker discovery. Chapters in Part II focus on biomarkers of other diagnoses/diseases, including sepsis, childhood renal diseases, pulmonary diseases, Alzheimer's, leishmaniasis, and heart failure. This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of diseases prognosis. The book is of considerable importance for a broad range of people including researchers, clinicians, and university students.
Download or read book Chagas Disease written by Jaime Marcelo Altcheh and published by Springer Nature. This book was released on 2019-09-09 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chagas disease is a potentially life threatening condition that was historically mainly endemic to Latin America. Over the last decade, however, the disease has spread to and is increasingly prevalent in other continents such as North America and Europe, with an estimated 7 million people infected worldwide. It is primarily transmitted by insect vectors that carry the parasite Trypanosoma cruzi, the disease agent. In areas where there is vector control and in non-endemic countries, it is mainly transmitted via congenital infection. Cardiac and gastrointestinal complications are common in untreated individuals. This book offers a comprehensive overview of Chagas disease, including its vectorial and congenital transmission, and molecular diagnosis, which is essential for screening, and developing and providing timely, effective anti-trypanosomal treatment. Written by experts working with infected patients on a daily basis, it discusses the pathogenesis of congenital, cardiac, gastrointestinal and oral Chagas disease, as well as its treatment and the pharmacological aspects of drug development in this area. Chapter "Chagas Disease Treatment Efficacy Biomarkers: Myths and Realities" is available open access under a via link.springer.com.
Download or read book Leishmaniasis Control and Elimination written by Om Prakash Singh and published by Frontiers Media SA. This book was released on 2022-02-07 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomarkers in Toxicology written by Vinood B. Patel and published by Springer Nature. This book was released on 2023-01-31 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook of the series Biomarkers in Disease informs comprehensively about all aspects of monitoring and detecting toxicity in the human body and model organisms. Biomarkers for assessing toxicity in diverse organs are presented and different assays and methods are explained. Single compounds and drugs and their toxicity for humans are shown and the methods for detection described. Similar to all the volumes of the Biomarkers in Disease series, the chapters are written by experts in their field, each chapter features key facts summarizing the most important aspects of its respective topic and the definitions of words and terms facilitate the reading and understanding. This handbook is a must-have for researchers in toxicology and biomedicine who analyze the effects of drugs and various other substances in the human body and in model organisms. It also serves as a thorough guide for clinicians and pharmacologists.
Download or read book Monitoring Metabolic Status written by Institute of Medicine and published by National Academies Press. This book was released on 2004-08-29 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. military's concerns about the individual combat service member's ability to avoid performance degradation, in conjunction with the need to maintain both mental and physical capabilities in highly stressful situations, have led to and interest in developing methods by which commanders can monitor the status of the combat service members in the field. This report examines appropriate biological markers, monitoring technologies currently available and in need of development, and appropriate algorithms to interpret the data obtained in order to provide information for command decisions relative to the physiological "readiness" of each combat service member. More specifically, this report also provides responses to questions posed by the military relative to monitoring the metabolic regulation during prolonged, exhaustive efforts, where nutrition/hydration and repair mechanisms may be mismatched to intakes and rest, or where specific metabolic derangements are present.
Download or read book Leishmaniases as Re emerging Diseases written by Farhat Afrin and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.
Download or read book Immuno Epigenetic Markers for Infectious Diseases written by Antonio C. R. Vallinoto and published by Frontiers Media SA. This book was released on 2020-01-14 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Encyclopedia of Molecular Pharmacology written by Stefan Offermanns and published by Springer Science & Business Media. This book was released on 2008-08-14 with total page 1515 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
Download or read book Molecular Advancements in Tropical Diseases Drug Discovery written by Gauri Misra and published by Academic Press. This book was released on 2020-05-12 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas. Updates knowledge about tropical diseases with recent advancements in the field Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action
Download or read book Oxidative Stress in Microbial Diseases written by Sajal Chakraborti and published by Springer. This book was released on 2019-11-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent advances in our understanding of the role of oxidants in microbial pathophysiology, providing valuable insights into the complex role of reactive oxygen species (ROS) in host-microbial interactions. The various chapters take readers through the function of ROS in infections ranging from viral to bacterial, and describe how microorganisms have developed complex strategies to not only avoid contact with phagocyte-derived oxidants, but also protect themselves from injury when oxidants are encountered. Featuring the latest research in the field of microbial diseases, this timely book is a ready reference for scientists looking to develop new anti-microbial drugs.
Download or read book Leishmaniasis written by David Claborn and published by BoD – Books on Demand. This book was released on 2014-03-19 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of all the parasitic diseases, leishmaniasis is one of the most diverse, with a variety of manifestations, from relatively minor cutaneous lesions to deadly visceral infections. It is also widespread, causing human disease in the Americas, Asia, Europe and Africa. The environments in which this disease occurs range from desert to tropical jungle to urban habitats. Not surprisingly, the literature on this disease is written in a variety of languages including Portuguese, Arabic, English and French among others. This book provides a synopsis in English of much of the recent research on leishmaniasis, with a focus on the epidemiology, diagnosis and treatment of the disease as described by researchers around the world, but with a focus on the research from Brazil and the Middle East.
Download or read book Drug Resistance in Leishmania Parasites written by Alicia Ponte-Sucre and published by Springer Science & Business Media. This book was released on 2012-09-04 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the main problems concerning therapeutic tools for the treatment of parasitic diseases, including leishmaniasis, is that some field parasites are naturally resistant to the classical drugs; additionally, current therapies may select parasites prone to be resistant to the applied drugs. These features are (at least partially) responsible for the disappointing persistence of the disease and resultant deaths worldwide. This book provides a comprehensive view of the pathology of the disease itself, and of parasitic drug resistance, its molecular basis, consequences and possible treatments. Scientists both from academic fields and from the industry involved in biomedical research and drug design, will find in this book a valuable and fundamental guide that conveys the knowledge needed to understand and to improve the success in combating this disease worldwide.
Download or read book Biology of C Reactive Protein in Health and Disease written by Waliza Ansar and published by Springer. This book was released on 2016-03-23 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP’s significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail. The book also includes clinical data studies and presents the latest research advances to further readers’ understanding of CRP.
Download or read book Pathogenesis of Leishmaniasis written by Abhay Satoskar and published by Springer Science & Business. This book was released on 2014-04-19 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent developments in several laboratories studying leishmaniasis. Sequencing of the human genome, as well as of the leishmania genome, has led to significant advances in our understanding of host-immune responses against leishmania, and mechanisms of infection-induced pathology, which is responsible for morbidity and mortality. Pathogenesis of Leishmaniasis focuses on the latest basic research into leishmaniasis, but also addresses how advances in understanding can be applied to prevention, control and treatment of what the WHO has classified a neglected tropical disease.
Download or read book Infectious Diseases and Your Health written by Prati Pal Singh and published by Springer. This book was released on 2018-11-27 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious Diseases and Your Health has the potential to impact and improve your life, and the lives of your loved ones. Every day, nearly 40, 000 people including small children and women die of infectious diseases. Many of these innocent lives could be saved. Your journey through the pages of this book will take you to an amazing world of infectious diseases. You will learn about various infectious diseases, how they can affect your life, the problems associated with their treatment and prevention, and how to overcome these problems. Additionally, you will hear the success story of new drug research, be introduced to the hard facts, and find fascinating pictures of microorganisms and parasites. The book provides instant solutions to several of your concerns about infectious diseases, and you will learn to live a highly productive, long and healthy life. So, join thousands of readers of this book worldwide, enhance your life and the lives of your loving family, become an informed healthy citizen, and contribute to achieving the UN’s Sustainable Development Goals. Let us never forget: life and quality of life are very precious.
