Download or read book Macromolecules 1 written by H.G. Elias and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this textbook is identical with its fourth German edi tion and it thus has the same goals: precise definition of basic phenomena, a broad survey of the whole field, integrated representation of chemistry, physics, and technology, and a balanced treatment of facts and comprehen sion. The book thus intends to bridge the gap between the often oversimpli fied introductory textbooks and the highly specialized texts and monographs that cover only parts of macromolecular science. The text intends to survey the whole field of macromolecular science. Its organization results from the following considerations. The chemical structure of macromolecular compounds should be inde pendent of the method of synthesis, at least in the ideal case. Part I is thus concerned with the chemical and physical structure of polymers. Properties depend on structure. Solution properties are thus discussed in Part 11, solid state properties in Part Ill. There are other reasons for dis cussing properties before synthesis: For example, it is difficult to understand equilibrium polymerization without knowledge of solution thermodynamics, the gel effect without knowledge of the glass transition temperature, etc. Part IV treats the principles of macromolecular syntheses and reactions.
Download or read book Equilibria and Kinetics of Biological Macromolecules written by Prof. Jan Hermans and published by John Wiley & Sons. This book was released on 2013-10-22 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progressively builds a deep understanding of macromolecular behavior Based on each of the authors' roughly forty years of biophysics research and teaching experience, this text instills readers with a deep understanding of the biophysics of macromolecules. It sets a solid foundation in the basics by beginning with core physical concepts such as thermodynamics, quantum chemical models, molecular structure and interactions, and water and the hydrophobic effect. Next, the book examines statistical mechanics, protein-ligand binding, and conformational stability. Finally, the authors address kinetics and equilibria, exploring underlying theory, protein folding, and stochastic models. With its strong emphasis on molecular interactions, Equilibria and Kinetics of Biological Macromolecules offers new insights and perspectives on proteins and other macromolecules. The text features coverage of: Basic theory, applications, and new research findings Related topics in thermodynamics, quantum mechanics, statistical mechanics, and molecular simulations Principles and applications of molecular simulations in a dedicated chapter and interspersed throughout the text Macromolecular binding equilibria from the perspective of statistical mechanics Stochastic processes related to macromolecules Suggested readings at the end of each chapter include original research papers, reviews and monographs, enabling readers to explore individual topics in greater depth. At the end of the text, ten appendices offer refreshers on mathematical treatments, including probability, computational methods, Poisson equations, and defining molecular boundaries. With its classroom-tested pedagogical approach, Equilibria and Kinetics of Biological Macromolecules is recommended as a graduate-level textbook for biophysics courses and as a reference for researchers who want to strengthen their understanding of macromolecular behavior.
Download or read book Structure Dynamics Interactions and Evolution of Biological Macromolecules written by C. Helene and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a Colloquium held at Orléans, France, July 5-9, 1982
Download or read book Physical Chemistry of Polyelectrolytes written by Tsetska Radeva and published by CRC Press. This book was released on 2001-02-21 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: An examination of the fundamental nature of polyelectrolytes, static and dynamic properties of salt-free and salt-added solutions, and interactions with other charged and neutral species at interfaces with applications to industry and medicine. It applies the Metropolis Monte Carlo simulation to calculate counterion distributions, electric potentials, and fluctuation of counterion polarization for model DNA fragments.
Download or read book Solution Dynamics Study of Biological Polyelectrolytes written by Hui Liu and published by . This book was released on 1996 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals written by Feroz Jameel and published by John Wiley & Sons. This book was released on 2010-08-09 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: A real-world guide to the production and manufacturing of biopharmaceuticals While much has been written about the science of biopharmaceuticals, there is a need for practical, up-to-date information on key issues at all stages of developing and manufacturing commercially viable biopharmaceutical drug products. This book helps fill the gap in the field, examining all areas of biopharmaceuticals manufacturing, from development and formulation to production and packaging. Written by a group of experts from industry and academia, the book focuses on real-world methods for maintaining product integrity throughout the commercialization process, clearly explaining the fundamentals and essential pathways for all development stages. Coverage includes: Research and early development phase–appropriate approaches for ensuring product stability Development of commercially viable formulations for liquid and lyophilized dosage forms Optimal storage, packaging, and shipping methods Case studies relating to therapeutic monoclonal antibodies, recombinant proteins, and plasma fractions Useful analysis of successful and failed products Formulation and Process Development Strategies for Manufacturing Biopharma-ceuticals is an essential resource for scientists and engineers in the pharmaceutical and biotech industries, for government and regulatory agencies, and for anyone with an interest in the latest developments in the field.
Download or read book Modern Methods of Polymer Characterization written by Howard G. Barth and published by John Wiley & Sons. This book was released on 1991-09-03 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the methods used for characterization of polymers. In addition to theory and basic principles, the instrumentation and apparatus necessary for methods used to study the kinetic and thermodynamic interactions of a polymer with its environment are covered in detail. Some of the methods examined include polymer separations and characterization by size exclusion and high performance chromatography, inverse gas chromatography, osmometry, viscometry, ultracentrifugation, light scattering and spectroscopy.
Download or read book Thermodynamics of Solutions written by Eli Ruckenstein and published by Springer Science & Business Media. This book was released on 2009-06-17 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of a number of papers regarding the thermodynamics and structure of multicomponent systems that we have published during the last decade. Even though they involve different topics and different systems, they have something in common which can be considered as the “signature” of the present book. First, these papers are concerned with “difficult” or very nonideal systems, i. e. systems with very strong interactions (e. g. , hyd- gen bonding) between components or systems with large differences in the partial molar v- umes of the components (e. g. , the aqueous solutions of proteins), or systems that are far from “normal” conditions (e. g. , critical or near-critical mixtures). Second, the conventional th- modynamic methods are not sufficient for the accurate treatment of these mixtures. Last but not least, these systems are of interest for the pharmaceutical, biomedical, and related ind- tries. In order to meet the thermodynamic challenges involved in these complex mixtures, we employed a variety of traditional methods but also new methods, such as the fluctuation t- ory of Kirkwood and Buff and ab initio quantum mechanical techniques. The Kirkwood-Buff (KB) theory is a rigorous formalism which is free of any of the - proximations usually used in the thermodynamic treatment of multicomponent systems. This theory appears to be very fruitful when applied to the above mentioned “difficult” systems.
Download or read book Introduction to Biophysical Methods for Protein and Nucleic Acid Research written by Jay A. Glasel and published by Academic Press. This book was released on 1995-11-20 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, Introduction to Biophysical Methods for Protein and Nucleic Acid Research serves as a text for the experienced researcher and student requiring an introduction to the field. Each chapter presents a description of the physical basis of the method, the type of information that may be obtained with the method, how data should be analyzed and interpreted and, where appropriate, practical tips about procedures and equipment.Key Features* Modern Use of Mass Spectroscopy* NMR Spectroscopy* Molecular Modeling and Graphics* Macintosh and DOS/Windows 3.x disks
Download or read book Properties of Polymers written by D.W. van Krevelen and published by Elsevier. This book was released on 2012-12-02 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt: Properties of Polymers: Their Correlation with Chemical Structure; Their Numerical Estimation and Prediction from Additive Group Contributions summarizes the latest developments regarding polymers, their properties in relation to chemical structure, and methods for estimating and predicting numerical properties from chemical structure. In particular, it examines polymer electrical properties, magnetic properties, and mechanical properties, as well as their crystallization and environmental behavior and failure. The rheological properties of polymer melts and polymer solutions are also considered. Organized into seven parts encompassing 27 chapters, this book begins with an overview of polymer science and engineering, including the typology of polymers and their properties. It then turns to a discussion of thermophysical properties, from transition temperatures to volumetric and calorimetric properties, along with the cohesive aspects and conformation statistics. It also introduces the reader to the behavior of polymers in electromagnetic and mechanical fields of force. The book covers the quantities that influence the transport of heat, momentum, and matter, particularly heat conductivity, viscosity, and diffusivity; properties that control the chemical stability and breakdown of polymers; and polymer properties as an integral concept, with emphasis on processing and product properties. Readers will find tables that give valuable (numerical) data on polymers and include a survey of the group contributions (increments) of almost every additive function considered. This book is a valuable resource for anyone working on practical problems in the field of polymers, including organic chemists, chemical engineers, polymer processers, polymer technologists, and both graduate and PhD students.
Download or read book Molecular Electro Optics written by Sonja Krause and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advanced Study Institute on Molecular Electro-Optics was held on the campus of the Rensselaer Polytechnic Institute, Troy, New York, USA, from July 14 through July 24, 1980. This Advanced Study Institute was attended by sixteen invited lecturers and by forty-eight other participants. The present volume contains the texts of all of the invited lectures presented at the Institute. Although these lectures were supplemented by many animated discussions and by numerous short contributed papers, it was not possible to include these in the present volume. Molecular electro-optics is a difficult subject for research because it incorporates areas of theoretical physics such as elec tromagnetic theory and hydrodynamics of rotational diffusion, ex perimental physics such as lasers, optics, electric pulsers, and data collection via analog to digital converters and signal aver agers, and physical chemistry of macromolecules and colloids in solution (colloid science, biophysical chemistry, double layer polarization). This volume includes chapters on all of these subjects as well as introductions to magnets-optics and to elec trophoretic light scattering. The Advanced Study Institute was sponsored mainly by the North Atlantic Treaty Organization whose financial support made this meeting possible. Additional financial aid was supplied by the National Institutes of Health of the USA through their Fogarty International Center and the National Institute for Arthritis, Metabolism, and Digestive Diseases. Industrial contri buters consisted of the General Electric Company, Cober Electronics, and Malvern Scientific Corporation.
Download or read book Physical Properties of Polyelectrolyte Solutions written by Michel Mandel and published by . This book was released on 1999 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Physicochemical Properties of Biopolymers Part 1 written by Martin Masuelli and published by Bentham Science Publishers. This book was released on 2017-07-05 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last two decades have seen a number of significant advances in the methodology for evaluating the molecular weight distributions of polydispersed macromolecular systems in solution at the molecular level. This reference presents reviews on the progress in different analytical and characterization methods of biopolymers. Readers will find useful information about combinations of complex biopolymer analysis such as chromatographic or membrane based fractionation procedures combined with multiple detectors on line (multi-angle laser light scattering or MALLS). Key topics include: • refractive index, UV-Vis absorbance and intrinsic viscosity detection systems, • advances in SEC-MALLS (size exclusion chromatography coupled to multi-angle laser light scattering) and FFF-MALLS (field flow fractionation coupled on line to MALLS), • HPSEC-A4F-MALLS, matrix-assisted laser-desorption ionization (MALDI) • electrospray ionization (ESI) mass spectrometry • nuclear magnetic resonance (NMR) spectroscopy This reference is intended for students of applied chemistry and biochemistry who require information about biopolymer analysis and characterization.
Download or read book Paper Chemistry written by J.C. Roberts and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the title of this book is Paper Chemistry, it should be considered as a text about the chemistry of the formation of paper from aqueous suspensions of fibre and other additives, rather than as a book about the chemistry of the raw material itself. It is the subject of what papermakers call wet-end chemistry. There are many other excellent texts on the chemistry of cellulose and apart from one chapter on the accessibility of cellulose, the subject is not addressed here. Neither does the book deal with the chemistry of pulp preparation (from wood, from other plant sources or from recycled fibres), for there are also many excellent texts on this subject. The first edition of this book was a great success and soon became established as one of the Bibles of the industry. Its achievement then was to collect the considerable advances in understanding which had been made in the chemistry of papermaking in previous years, and provide, for the first time, a sound physico chemical basis of the subject. This new edition has been thoroughly updated with much new material added. The formation of paper is a continuous filtration process in which cellulosic fibres are formed into a network which is then pressed and dried. The important chemistry involved in this process is firstly the retention of col loidal material during filtration and secondly the modification of fibre and sheet properties so as to widen the scope for the use of paper and board products.
Download or read book Polyelectrolytes written by Masanori Hara and published by CRC Press. This book was released on 1992-11-12 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aims to provide in-depth coverage of recent advances in all important areas of polyelectrolyte research and applications. Topics covered in this text include scaling theory, dynamic light scattering, neutron scattering, biopolymers and ionomers.
Download or read book Electrical Fluctuations in Polyelectrolytes written by José Antonio Fornés and published by Springer. This book was released on 2016-08-04 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief is the result of the research the author has performed in recent years covering electrical fluctuations in numerous systems, including molecular electrical fluctuations, ionic fluctuations, ionic dielectric relaxation, spherical and cylindrical polyelectrolytes, ionic polarizability in polyelectrolytes, pH fluctuation in vesicles and electrical fluctuations in proteins. The importance of estimating electrical fluctuations resides in its richness of information and omnipresence in biological systems. In order to understand how these systems work it is vital to know the magnitude of their electrical fluctuations. Electromagnetic fluctuations are the origin of London (Van der Waals) forces between molecules, and Lifshitz forces between macro objects. Protonic fluctuations are the origin of Kirkwood and Shumaker forces between molecules and pH fluctuations. Furthermore, protonic fluctuations could be the cause of the dielectric increment of proteins in solution. Local electrical fluctuations can influence chemical reactions and so on. This book addresses the interplay of these pervasive phenomena. .
Download or read book Biophysical Chemistry written by Charles R. Cantor and published by Macmillan. This book was released on 1980-04-15 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three-part series remains the definitive text on the physical properties of biological macromolecules and the physical techniques used to study them. It is appropriate for a broad spectrum of advanced undergraduate and graduate courses and serves as a comprehensive reference for researchers. Part I: The Conformation of Biological Macromolecules 1980, paper, 365 pages, 158 illustrations 0-7167-1188-5 Part II: Techniques for the Study of Biological Structure and Function 1980, paper, 365 pages, 158 illustrations 0-7167-1190-7 Part III: The Behavior of Biological Macromolecules 1980, paper, 597 pages, 243 illustrations 0-7167-1192-3
