Download or read book Bioenergetics and Metabolism of Eukaryotic Cell Proliferation written by Zhaoqi Li (Ph. D.) and published by . This book was released on 2021 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular growth and proliferation necessitates the transformation of cell-external nutrients into biomass. Strategies of biomass accumulation across the kingdoms of life are diverse and range from carbon fixation by autotrophic organisms to direct biomass incorporation of consumed nutrients by heterotrophic organisms. The goal of this dissertation is to better understand the divergent and convergent modes of metabolism that support biomass accumulation and proliferation in eukaryotic cells. We first determined that the underlying mechanism behind why rapidly proliferating cells preferentially ferment the terminal glycolytic product pyruvate is due to an intrinsic deficiency of respiration to regenerate electron acceptors. We tested this model across an assorted array of proliferating cells and organisms ranging from human cancer cells to the baker’s yeast Saccharomyces cerevesiae. We next determined that a major metabolic pathway of avid electron acceptor consumption in the context of biomass accumulation is the synthesis of lipids. Insights from this work has led to the realization that net-reductive pathways such as lipid synthesis may be rate-limited by oxidative reactions. Lastly, we established the green algae Chlorella vulgaris as a model system to study the comparative metabolism of photoautotrophic and heterotrophic growth. We determined that heterotrophic growth of plant cells is associated with aerobic glycolysis in a mechanism that may be suppressed by light. Collectively, these studies contribute to a more holistic understanding of the bioenergetics and metabolic pathways employed by eukaryotic cells to accumulate biomass and lay the foundation for future studies to understand proliferative metabolism.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mitochondria and Anaerobic Energy Metabolism in Eukaryotes written by William F. Martin and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-12-07 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are sometimes called the powerhouses of eukaryotic cells, because mitochondria are the site of ATP synthesis in the cell. ATP is the universal energy currency, it provides the power that runs all other life processes. Humans need oxygen to survive because of ATP synthesis in mitochondria. The sugars from our diet are converted to carbon dioxide in mitochondria in a process that requires oxygen. Just like a fire needs oxygen to burn, our mitochondria need oxygen to make ATP. From textbooks and popular literature one can easily get the impression that all mitochondria require oxygen. But that is not the case. There are many groups of organismsm known that make ATP in mitochondria without the help of oxygen. They have preserved biochemical relicts from the early evolution of eukaryotic cells, which took place during times in Earth history when there was hardly any oxygen avaiable, certainly not enough to breathe. How the anaerobic forms of mitochondria work, in which organisms they occur, and how the eukaryotic anaerobes that possess them fit into the larger picture of rising atmospheric oxygen during Earth history are the topic of this book.
Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2018-01-07 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.
Download or read book The Plant Cell Cycle written by Dirk Inzé and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the study of the plant cell cycle has become of major interest, not only to scientists working on cell division sensu strictu , but also to scientists dealing with plant hormones, development and environmental effects on growth. The book The Plant Cell Cycle is a very timely contribution to this exploding field. Outstanding contributors reviewed, not only knowledge on the most important classes of cell cycle regulators, but also summarized the various processes in which cell cycle control plays a pivotal role. The central role of the cell cycle makes this book an absolute must for plant molecular biologists.
Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.
Download or read book Biology for AP Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
Download or read book Principles of Bioenergetics written by Vladimir P. Skulachev and published by Springer Science & Business Media. This book was released on 2012-12-15 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry. Bioenergetics concerns energy transductions occurring in living systems and this book pays special attention to molecular mechanisms of these processes. The main subject of the book is the "energy coupling membrane" which refers to inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases) are also part of this membrane. Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants.
Download or read book Cells Molecules and Mechanisms written by Eric Wong and published by Axolotl Academic Publishing. This book was released on 2009 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.
Download or read book AMP activated Protein Kinase written by Mario D. Cordero and published by Springer. This book was released on 2016-11-02 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes. This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease.
Download or read book Basic Exercise Physiology written by Moran S. Saghiv and published by Springer Nature. This book was released on 2020-08-26 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the assessment of human performance and the role of different exercise modes both in a laboratory and clinical setting. Details of how to successfully perform basic laboratory procedures for exercise training in health and disease, as well as how to apply non-invasive measurements in exercise physiology are provided. Chapters cover how to appropriately use a range of measures in assessing pulmonary function, anaerobic function and oxygen uptake. Techniques for cardiopulmonary rehabilitation and the mechanisms associated with thermoregulation are also described. Interactive exercises enable readers to easily assimilate key concepts and develop a thorough understanding of the topic. Basic Exercise Physiology provides both trainees and professional healthcare staff interested in exercise physiology with a detailed and practically applicable resource on the topic.
Download or read book Encyclopedic Reference of Parasitology written by Heinz Mehlhorn and published by Springer Science & Business Media. This book was released on 2001-05-21 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides a comprehensive review of the facts and trends in veterinarian and human parasitology. Several internationally renowned specialists have been added to the authors of the first edition, and the whole is now organised in an encyclopedic arrangement of comprehensive keywords, thus speeding up the search for information.
Download or read book Cell Cycle Regulation written by Philipp Kaldis and published by Results and Problems in Cell Differentiation. This book was released on 2006-06-26 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a state-of-the-art summary of the latest achievements in cell cycle control research with an outlook on the effect of these findings on cancer research. The chapters are written by internationally leading experts in the field. They provide an updated view on how the cell cycle is regulated in vivo, and about the involvement of cell cycle regulators in cancer.
Download or read book Biological Wastewater Treatment written by Mogens Henze and published by IWA Publishing (International Water Assoc). This book was released on 1881 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: For information on the online course in Biological Wastewater Treatment from UNESCO-IHE, visit: http://www.iwapublishing.co.uk/books/biological-wastewater-treatment-online-course-principles-modeling-and-design Over the past twenty years, the knowledge and understanding of wastewater treatment have advanced extensively and moved away from empirically-based approaches to a first principles approach embracing chemistry, microbiology, physical and bioprocess engineering, and mathematics. Many of these advances have matured to the degree that they have been codified into mathematical models for simulation with computers. For a new generation of young scientists and engineers entering the wastewater treatment profession, the quantity, complexity and diversity of these new developments can be overwhelming, particularly in developing countries where access is not readily available to advanced level tertiary education courses in wastewater treatment. Biological Wastewater Treatment addresses this deficiency. It assembles and integrates the postgraduate course material of a dozen or so professors from research groups around the world that have made significant contributions to the advances in wastewater treatment. The book forms part of an internet-based curriculum in biological wastewater treatment which also includes: Summarized lecture handouts of the topics covered in book Filmed lectures by the author professors Tutorial exercises for students self-learning Upon completion of this curriculum the modern approach of modelling and simulation to wastewater treatment plant design and operation, be it activated sludge, biological nitrogen and phosphorus removal, secondary settling tanks or biofilm systems, can be embraced with deeper insight, advanced knowledge and greater confidence.
Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Download or read book Membrane Bioenergetics written by Vladimir P. Skulachev and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane bioenergetics is one of the most rapidly growing areas within physico-chemical biology. Main aspects treated in this book include energy conservation and utilization by membrane-linked molecular mechanisms such as intracellular respiration, photosynthesis, transport phenomena, rotation of bacterial flagella, and the regulation of heat production.
Download or read book Ecology of Protozoa written by Genoveva F. Esteban and published by Springer Nature. This book was released on 2021-01-04 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasises the important role that protozoa play in many natural ecosystems. To shed new light on their individual adaptive skills, the respective chapters examine the ecology and functional biology of this diverse group of eukaryotic microbes. Protozoa are well-established model organisms that exemplify many general problems in population ecology and community ecology, as well as evolutionary biology. Their particular characteristics, like large population sizes, life cycles and motile sensory behaviour, have a profound impact on their survival, distribution, and interaction with other species. Thus, readers will also be introduced to protozoan habitats in a broad range of environments. Even though this group of unicellular organisms is highly diverse, the authors focus on shared ecological patterns. Students and scientists working in the areas of eukaryotic microbiology and ecology will appreciate this updated and revised 2nd Edition as a valuable reference guide to the “lifestyles” of protozoa.
