Download or read book The Specificity and Action of Animal Bacterial and Plant Toxins written by Pedro Cuatrecasas and published by Springer. This book was released on 2013-12-17 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Natural Products Chemistry written by Koji Nakanishi and published by University Science Books. This book was released on 1974 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Toxinology written by W. T. Shier and published by CRC Press. This book was released on 2020-08-26 with total page 825 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized primarily around the mechanisms of action of the toxins at the biochemical, physiological and pathological level, rather than by source, the handbook covers most toxins which have been clearly identified and characterized, but emphasizes toxins that are more important by virtue of the sign

Download or read book Alkaloids Chemical and Biological Perspectives written by S.W. Pelletier and published by Elsevier. This book was released on 1999-04-29 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 13 of this series presents five timely reviews of research on alkaloids such as new developments in the chemistry and biology of alkaloids from amphibian skins. It provides a synopsis and tabulation of the hundreds of alkaloids that have been detected, with an emphasis on occurrence, structure, dietary origins, and biological activity. Alkaloids containing the 1, 2, 3, 3a, 8, 8a - hexahydropyrrolo [2,3b] indole ring system and the cyclotryptamines are discussed. An exhaustive list of available structures is provided. The chemical and biological structures have been evaluated critically so as to identify existing errors and expose irregularities in appearance or biological function. In addition, attention is drawn to the possible implications of the accumulated knowledge related to the synthesis, occurrence, and biochemistry of this class of alkaloids.Recent work on alkaloids containing the comparatively non – basic pyrrole ring system is summarized. One of the chapters covers isolation, structure elucidation, biological activity, and selected chemical syntheses of certain pyrrole alkaloids.Recent developments in the chemistry of diterpenoid and norditerpenoid alkaloids occurring in Aconitum, Delphinium and Consolida genera of the Ranunculaceae family used in Chinese and Indian medicine are surveyed and the book ends with a focus on transition metal – catalyzed carbonylations as efficient and novel approaches to the construction of piperidine, izidine and quinazoline alkaloids, which occur in great numbers in nature.

Download or read book The Alkaloids Chemistry and Pharmacology written by and published by Academic Press. This book was released on 1983-07-19 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Alkaloids: Chemistry and Pharmacology

Download or read book Medical Toxicology of Natural Substances written by Donald G. Barceloux and published by John Wiley & Sons. This book was released on 2012-03-07 with total page 1196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest and information in the field of medical toxicology has grown rapidly, but there has never been a concise, authoritative reference focused on the subjects of natural substances, chemical and physical toxins, drugs of abuse, and pharmaceutical overdoses. Medical Toxicology of Natural Substances finally gives you an easily accessible resource for vital toxicological information on foods, plants, and animals in key areas in the natural environment.

Download or read book Handbook of Plant and Animal Toxins in Food written by Gulzar Ahmad Nayik and published by CRC Press. This book was released on 2022-04-18 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of naturally occurring toxins in plant and animal foods represents one of the most significant food safety issues, drawing the attention of both scientists and regulators alike. This unexplored area related to food quality is indeed a big concern for consumers, various regulatory authorities, and food industries. Apart from essential nutrients, several food crops are capable of producing a vast array of nonnutritious secondary metabolic products. These toxins produced as secondary metabolites have the potential to exhibit both beneficial and deleterious effects in both human beings and animals. Nevertheless, there has been huge progress in agricultural practices and food processing technologies, but still the number of nonnutritive substances and naturally derived toxins persist in our diet. Handbook of Plant and Animal Toxins in Food: Occurrence, Toxicity, and Prevention, focuses on various selected toxins in foods derived from plants as well as animals. The prominent plant toxins include solanine and chaconine, mushroom toxins, phytates, tannins, oxalates, goitrogens, gossypol, phytohemagglutinins, erucic acid, saponins, cyanogenic glycosides, enzyme inhibitors, BOAA (lathyrogens), toxic amino acids and toxic fatty acids. The prominent animal toxins covered in the book include various seafood toxins, shellfish toxins and biogenic amines. Key Features: Presents complete information about a plethora of toxins Provides quick and easy access to data on major plant and animal toxins Covers distribution of toxins in the plant and animal kingdom Provides comprehensive information on chemistry, safety and precautions of each toxin Commencing with a brief introduction of food toxins, this book is designed in such a way that the readers will be introduced to toxicity, safety and occurrence of each toxin selected. It also discusses the in-depth detailed information on food poisoning and its prevention. The book will also shed light on foodborne illness associated with toxins. The primary audience for this work will be food scientists, food toxicologists, university scholars and college students. Furthermore, the book will be of immense help for public health officials, pharmacologists, and food safety officers who are involved with enforcing regulations meant to ensure the safety of a particular food

Download or read book International Review of Neurobiology written by and published by Academic Press. This book was released on 1988-07-01 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Neurobiology

Download or read book Ion Channel Reconstitution written by C. Miller and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now over 30 years since the idea of ion-conducting pores burst on the elec trophysiological scene, 15 years since these were generalIy realized to be mem brane-spanning proteins, and 10 years since the first observations of single ion channels from higher organisms were made. During the past 5 years, several integral membrane channel proteins have been purified in a functionalIy competent state: the nicotinic acetylcholine receptor, the Na + channel, mitochondrial "VDAC," and a variety of porins. The stage is thus set to attack ion channels in the same ways that biochemists have been attacking enzymes for decades: isolation folIowed by functional analysis in as simple a system as possible, with a view towards understanding the molecular mechanisms ofthe protein's behavior and how this is related to the underlying molecular structure. This is always a daunting task, alI the more so with ion channels because of our still primitive and scanty understanding of channel structures and because of the difficulty in iso lating functionally active channel proteins. In this volume, which can be considered a biochemically slanted companion to Sakmann and Neher's Single-Channel Recording, I have tried to present a view of the current landscape of ion-channel reconstitution. These chapters illustrate not only the different approaches and techniques of the major practitioners of ion channel reconstitution but, as importantly, the varied motivations for doing this kind of work.

Download or read book Handbook on Biological Warfare Preparedness written by S.J.S. Flora and published by Academic Press. This book was released on 2019-10-05 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. - Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins - Discusses medical countermeasures, including vaccines and post-exposure therapeutics - Includes a comprehensive review of current methods of detection

Download or read book Toxicology and Human Environments written by Ernest Hodgson and published by Academic Press. This book was released on 2012-09-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved. This volume is a first attempt to integrate toxicological studies of all of the many human environments, both indoor and outdoor, and their complex interrelationships. Included are considerations of natural environments, the agroecosystem, occupational, urban and domestic environments as well as the environment associated with Superfund sites and military deployments. The primary emphasis is on public health, including the potential health effects of toxicants found in different environments, the bioprocessing of such toxicants in humans and surrogate animals and the principles of risk analysis. Approaches the toxicology of human environments in a new and unique way, stressing the complex interrelationships of all human environments and the implication for human and environmental health Each chapter is written by an acknowledged expert and is addressed to those interested in the broader implications of the environmental modifications that are always associated with the activities of humans living and working in them

Download or read book Strategies for the Total Synthesis of Quassin and Batrachotoxin written by Theophilus Leapheart and published by . This book was released on 1983 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemistry of condensed tannins has hitherto represented a relatively unattractive and therefore neglected area of study; one in which the weight of research effort involved is invariably disproportionate to the results achieved, in which the participating schools generally confine their approach to specific molecular species, and in which as yet no consensus has been reached regarding likely precursors. The problems which beset those engaged in this field represent a combined function of the abnormal complexity of the gradational range of oligomers of increasing mass and affinity for substrates which typify most extracts rich in tannins, and the consequent problem of their isolation and purification, the high chirality of tannin oligomers, the need to contend with the phenomenon of dynamic 'rotational isomerism about interflavanoid bonds in the IH n.m.r. spectral interpretation of their derivatives, the lack of precise knowledge regarding the points of bonding at nucleophilic centres, and the obvious limitations of a hitherto predominantly analytical approach. The last of these reflects the need for a general method of synthesis which permits unambiguous proof of both structure and absolute configuration also at higher oligomeric levels. With these objectives in mind we initiated a purely synthetic approach based on the premise that flavan-3,4-diols as source of electrophilic flavanyl-4-carbocations, and flavan-3-0Is as nucleophiles (cf 1,2) represent the prime initiators of a process of repetitive condensation in which the immediate products also represent the sequent nucleophilic substrates.

Download or read book Strange Chemistry written by Steven Farmer and published by John Wiley & Sons. This book was released on 2017-06-14 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book opens the audience’s eyes to the extraordinary scientific secrets hiding in everyday objects. Helping readers increase chemistry knowledge in a fun and entertaining way, the book is perfect as a supplementary textbook or gift to curious professionals and novices. • Appeals to a modern audience of science lovers by discussing multiple examples of chemistry in everyday life • Addresses compounds that affect everyone in one way or another: poisons, pharmaceuticals, foods, and illicit drugs; thereby evoking a powerful emotional response which increases interest in the topic at hand • Focuses on edgy types of stories that chemists generally tend to avoid so as not to paint chemistry in a bad light; however, these are the stories that people find interesting • Provides detailed and sophisticated stories that increase the reader’s fundamental scientific knowledge • Discusses complex topics in an engaging and accessible manner, providing the “how” and “why” that takes readers deeper into the stories

Download or read book Sustaining Life written by Eric Chivian and published by Oxford University Press. This book was released on 2008-06-02 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Earth's biodiversity-the rich variety of life on our planet-is disappearing at an alarming rate. And while many books have focused on the expected ecological consequences, or on the aesthetic, ethical, sociological, or economic dimensions of this loss, Sustaining Life is the first book to examine the full range of potential threats that diminishing biodiversity poses to human health. Edited and written by Harvard Medical School physicians Eric Chivian and Aaron Bernstein, along with more than 100 leading scientists who contributed to writing and reviewing the book, Sustaining Life presents a comprehensive--and sobering--view of how human medicines, biomedical research, the emergence and spread of infectious diseases, and the production of food, both on land and in the oceans, depend on biodiversity. The book's ten chapters cover everything from what biodiversity is and how human activity threatens it to how we as individuals can help conserve the world's richly varied biota. Seven groups of organisms, some of the most endangered on Earth, provide detailed case studies to illustrate the contributions they have already made to human medicine, and those they are expected to make if we do not drive them to extinction. Drawing on the latest research, but written in language a general reader can easily follow, Sustaining Life argues that we can no longer see ourselves as separate from the natural world, nor assume that we will not be harmed by its alteration. Our health, as the authors so vividly show, depends on the health of other species and on the vitality of natural ecosystems. With a foreword by E.O. Wilson and a prologue by Kofi Annan, and more than 200 poignant color illustrations, Sustaining Life contributes essential perspective to the debate over how humans affect biodiversity and a compelling demonstration of the human health costs. It is the winner of the Gerald L. Young Book Award in Human Ecology Best Sci-Tech Books of 2008 for Biology by Gregg Sapp of Library Journal

Download or read book Pharmacology written by Miles Hacker and published by Academic Press. This book was released on 2009-06-19 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research. - Uses individual drugs to explain molecular actions - Full color art program explains molecular and chemical concepts graphically - Logical structure reflecting the current state of pharmacology and translational research - Covers such intricacies as drug resistance and cell death - Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

Download or read book Comprehensive Natural Products II written by and published by Elsevier. This book was released on 2010-03-05 with total page 7944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas among the established natural products research community—which includes chemists, biochemists, biologists, botanists, and pharmacologists Informs and inspires students and newcomers to the field with accessible content in a range of delivery formats Includes 100% new content, with more than 6,000 figures (1/3 of these in color) and 40,000 references to the primary literature, for a thorough examination of the field Highlights new research and innovations concerning living organisms and their distinctive role in our understanding and improvement of human health, genomics, ecology/environment, and more Adds to the rich body of work that is the first edition, which will be available for the first time in a convenient online format giving researchers complete access to authoritative Natural Products content