Download or read book Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging written by M. A. Hayat and published by Academic Press. This book was released on 2016-12-28 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections. - Presents the most advanced information regarding the role of the autophagic system in life and death - Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both - Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation - Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment - Includes chapters authored by leaders in the field around the globe—the broadest, most expert coverage available

Download or read book Metabolic Autophagy written by Siim Land and published by Metabolic Autophagy Diet. This book was released on 2019-02-09 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intermittent Fasting for Longevity and Performance Your cells are constantly monitoring the nutrient status of the cells to determine whether or not to conserve energy or to promote growth. **One of the few known ways of increasing lifespan in almost all species is caloric restriction and energy deprivation.** This triggers many metabolic pathways and processes that make the organism more adaptable to environmental stressors and thus live longer. **The metabolism has two sub-categories or sub-processes called anabolism and catabolism. ** * Anabolism, meaning 'upward' in Greek, describes the synthesis of biological molecules to build up new physical matter in the body. * Catabolism, meaning 'downward' in Greek, describes the breaking down of biological molecules to release energy. This can apply to the breakdown of bodily tissue as well as the digestion of food that then gets assimilated into the body through anabolic processes. In addition to 'Metabolic', you can also find another word in the title - 'Autophagy', which translates from Ancient Greek into 'self-devouring' or 'eating of self'. This is central to the main practice of this book. By maintaining a balance between anabolism and catabolism, you can effectively extend your lifespan. The process of autophagy entails your healthy cells devouring the old, worn-out, weak ones and converting them back into energy. It's literally your body eating itself and using that to maintain homeostasis. There are many longevity-boosting benefits to this as illustrated in virtually all other species. This book is a collection of guidelines about the principles of the anabolic-catabolic cycles in regards to nutrition and exercise. It's definitely not a panacea - a solution or remedy for all conditions and circumstances. Instead, it's a very specific protocol that's not supposed to apply for all situations. **Metabolic Autophagy will teach you:** * What increases lifespan in humans and other species * Why there's so much disease and obesity in society * How to promote health and longevity with intermittent fasting * What is Autophagy and how it works * How to age slower and be vigorous throughout your life * Which foods make you live longer and build muscle * How the nutrient regulators of mTOR, AMPK, sirtuins, FOXO proteins, hormesis and others affect longevity * What are circadian rhythms and how they affect your health * Metabolic Autophagy Foods list and their anabolic-catabolic score * Supplements that support muscle growth and longevity * Many extras and bonuses in regards to food and exerciseSiim Land is a best-selling author, anthropologist, entrepreneur, high-performance coach and a biohacker who writes about optimizing health and human performance.This book incorporates daily lifestyle and dietary practices that help to cross the chasm between longevity and high performance.

Download or read book Autophagy written by Thomas Hawthorn and published by scott m ecommerce. This book was released on 2019-06-24 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how a one day starvation secret won the nobel prize. And how you can use it to lose weight and promote long-term health. In 2016, Yoshinori Ohsumi won the Nobel Prize for his research on Autophagy. Now, not only does autophagy have lifechanging weight loss benefits… It may help treat cancer and neurodegenerative diseases like Alzheimer’s. Why has this unique type of fasting only become established in the past couple of years? It’s simple, the fat cats of our food industry establishment have billions riding on the outdated “3 square meals a day” lifestyle. And not only is this typical American lifestyle outdated, it’s downright dangerous! However, there is another way. And inside this breakthrough book you’ll discover: How to lose weight faster while intermittent fasting IBS pain? You can blame this common food 5 superfoods you can find at your local supermarket How inflamed is your body right now? Exactly what to ask your doctor to find out the truth. How to increase autophagy without fasting for several days in a row 7 best foods for nurturing gut health Eat this “forgotten food” to reverse plaque build up in your arteries How to properly do a water fast without feeling weak or getting hungry. A handful of this food cuts risk of heart disease by 24% 1 in 4 supplements failed quality tests at a leading independent lab. Discover which ones to throw out How to lose weight without working out every day 3 beginner mistakes which actually prevent autophagy, and how to avoid them Do you get autophagy during 16/8 fasting? The surprising truth …and much, much more. Plus countless other health secrets… Including this “miracle beverage” which researchers at the University of Minnesota found lowered diabetes risk by 33%... drinking this also boosts the effectiveness of your fast… plus one drink to avoid which sneakily breaks your fast You’ll also discover How to avoid starvation mode while fasting The raw truth about extended water fasting Is too much autophagy bad? Get the answer from the world’s leading expert Why do dogs who eat 1 meal a day live 20% longer than dogs who eat 3 meals a day? The 3 benefits of autophagy you probably didn’t know about Autophagy success stories – how one obese Mom lost 90lbs in less than 6 months and cured her diabetes All written in plain English. So you don’t need a medical degree to understand and apply what’s inside. This is not just a diet fad. This is a long-term gamechanger in the health and longevity space. Here’s the deal. The traditional “calories in, calories out” weight loss method no longer works. And restrictive low-fat or vegan diets often leave you hungry and irritable. However, when you combine the keto diet with a 2016 Nobel Prize winning breakthrough known as autophagy – you get the keto diet on steroids So take control of your life and show your friends and family that there is a simple way to lose weight and be happy – scroll up and click “add to cart”

Download or read book Autophagy Biology and Diseases written by Zheng-Hong Qin and published by Springer Nature. This book was released on 2019-11-27 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.

Download or read book Autophagy written by Daniel Klionsky and published by CRC Press. This book was released on 2003-12-15 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting in the early 1970s, a type of programmed cell death called apoptosis began to receive attention. Over the next three decades, research in this area continued at an accelerated rate. In the early 1990s, a second type of programmed cell death, autophagy, came into focus. Autophagy has been studied in mammalian cells for many years. The recen

Download or read book Autophagy written by Nicholas Ktistakis and published by Humana Press. This book was released on 2019-01-05 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details a comprehensive and extensive set of protocols for the study of autophagy in vitro and in vivo. Chapters focus on mammals, various model organisms, and provide protocols for the study of autophagy-related processes outside of the canonical autophagy pathways. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Autophagy: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Download or read book Autophagy and Cancer written by Hong-Gang Wang and published by Springer Science & Business Media. This book was released on 2013-03-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it. ​

Download or read book Exercise Autophagy and Chronic Diseases written by Ning Chen and published by Springer Nature. This book was released on 2021-09-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book establishes a bridge between exercise-mediated functional status of autophagy and non-communicable chronic diseases for elucidating and clarifying the corresponding signal pathways and underlying mechanisms. The book consists of 13 chapters focusing on the in-depth discussion on signal pathways for regulating the functional status of autophagy for the prevention, treatment and rehabilitation of chronic diseases, the optimization of exercise intervention strategies for common and frequently-occurring chronic diseases, and the development of exercise mimetic pills for the persons with disability for exercise performance, or the persons without willing to exercise. This book is interesting and will be useful to a wide readership in the various fields of exercise science, exercise fitness, sports medicine, preventive medicine, and functional foods.

Download or read book Autophagy Biology and Diseases written by Zhiping Xie and published by Springer Nature. This book was released on 2021-07-14 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 3 focuses on the technical aspects of autophagy research. It is comprised of two parts. The first part discusses the basic process of autophagy, including its overall classification and individual stages in the life cycle of autophagosomes. The second part discusses the tools, strategies, and model systems in current autophagy research, including cell and animal models, detection and manipulation methods, as well as screening, genomic, proteomic and bioinformatic approaches. The book is written and edited by a team of active scientists. It is intended as a practical reference resource for interested researchers to get started on autophagy studies.

Download or read book Autophagy Fasting With Water for Beginners written by Eric Fung and published by . This book was released on 2019-05-15 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you or someone you know is struggling to lose weight, you know exactly how agonizing such an experience can be. Not only does it cause significant emotional or health damage, being overweight can cause you to lose your sense of self. But did you know that there are simple things you can do to transform your body, win your weight loss battles and regain your health with water fasting? "Autophagy Fasting with Water for Beginners" is your comprehensive go-to guide to fasting your way to autophagy and losing weight seamlessly regardless of your current diet. Within the pages of this special weight loss log book, authors Jason Berg and Eric Fung reveal how you can get quicker weight loss results in half the time you would with regular dieting and exercise programs. Whether your goal is to lose weight painlessly, look better, improve the health of your family, or you simply want to discover an effective way to find relief from common health problems and live in total health, this book will empower you with deep and riveting information. Inducing complete autophagy with fasting doesn't have to be traumatic and painful. With this book, you'll be amazed at how simple and easy it is to lose weight and keep it off for good using water fasting. Within the pages of this book, you'll discover: What autophagy is and how to trigger a complete lifestyle change with it Practical guidance and extensive information for losing stubborn fats using autophagy and water fasting How to propel yourself to total health and longevity with autophagy The surprising secrets about autophagy that can help you detox your body and reclaim your health How to induce autophagy and get great results even if you are a beginner And much more! This book is just the perfect manual for any healthy, quick, and painless weight loss plan. If you are tired of going through the cycle of losing and gaining weight, this book is for you. Click on the "Buy with 1-Click Button NOW!"

Download or read book The Switch written by James W. Clement and published by Simon and Schuster. This book was released on 2019-12-31 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can you lose weight, ease chronic conditions, and stay healthier longer? Discover how to “rewrite your health destiny” (David Perlmutter, MD, #1 New York Times bestselling author of Grain Brain) with this accessible book that teaches you how to flip the switch on your metabolism with intermittent fasting, protein cycling, and keto. Within each of us is an ancient mechanism that eliminates toxic materials, initiates fat burning, and protects cells from becoming dysfunctional—or turning cancerous. It’s called autophagy, and when it’s turned on, the complex operation not only can slow down the aging process, it can optimize biological function as a whole, helping to stave off all manner of diseases and affording us the healthy life spans we never thought possible. It’s the body’s ultimate switch to life. So how can we positively activate this switch? How frequently should we fast and for how long? Which foods dial up autophagy or, conversely, turn it down? How much exercise and what types are recommended? What’s the sweet spot between intermittent fasting, protein cycling, and ketogenic eating? Backed by a wealth of scientific data and featuring a gallery of guidelines to follow for lasting results, “The Switch offers a paradigm shift in the way we think about health—and how to avoid decline and illness. This is a must read” (Mark Hyman, #1 New York Times bestselling author).

Download or read book Autophagy of the Nervous System written by Zhenyu Yue and published by World Scientific. This book was released on 2012 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is autophagy? Why would neurons digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as an accomplice to cell death in others? By what mechanisms are autophagy-related processes dysregulated in neurological diseases, and are there therapeutic strategies to correct or compensate for their dysfunction? This book provides an expert view of major concepts in autophagy research with a focus on autophagy in neurons. Experimental evidence for evolutionarily conserved and specialized regulatory mechanisms for autophagy in the mammalian nervous system will be presented, including recent data on braking mechanisms. Areas of intersection with cell death, the ubiquitin-proteasome system, chaperone-mediated autophagy, and the endocytic pathway will be reviewed, along with emerging areas of mitochondrial autophagy (mitophagy) and the autophagic regulation of neuritic/synaptic processes. Advances in delineating mechanisms by which autophagy is involved in the pathophysiology of neurological disorders, including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, ischemia/hypoxia and lysosomal storage diseases, will be discussed along with current drug development strategies targeting autophagy.

Download or read book Jump Start Autophagy written by Melissa Mayer and published by Simon and Schuster. This book was released on 2019-10-22 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: Harness your body’s natural cell-rejuvenating process for amazing health benefits To maintain good health, it is vital that your body’s natural detoxing process of cleaning out damaged cells and regenerating new ones, known as autophagy, is working well. Dysfunctional cellular processes can cause all kinds of serious issues, from premature aging to cancer. On the other hand, a healthy autophagy process can reduce inflammation, prevent skin issues, boost metabolism, and even heal autoimmune issues. Jump Start Autophagy will give you all the tools you need to hack your cells for a longer, healthier life. The book will walk you through the science of autophagy, how it works, and why our bodies need it. It will break down the different ways our bodies are signaled to kick start autophagy; and, best of all, show you concrete examples, activities, and methods to push your own body into autophagy to achieve healthier skin, boost your metabolism, heal inflammation, and so much more.

Download or read book Autophagy written by Alaina W. Bolton and published by . This book was released on 2020-07-26 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Textbook of Pathology E Book written by Rajeswari Kathiah and published by Elsevier Health Sciences. This book was released on 2024-09-18 with total page 1210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Pathology - E-Book

Download or read book Autophagy and Metabolism written by Dhruv Kumar and published by Elsevier. This book was released on 2022-08-06 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy and Metabolism: Potential Target for Cancer Therapy presents updates on autophagy in cancer metabolism and how it can be used to develop new, more efficient treatments. Written by experts in the field, the book presents recent research and explains how to translate it to the clinical setting. Sections discuss tumor cell metabolism and autophagy as therapeutic targets, autophagy regulation in cancer, signaling pathways in metabolic dysregulation in solid tumors, metabolic stress and cell death pathways, and the role of the tumor microenvironment. In addition, topics cover combined targeting autophagy, metabolism for cancer therapy, and the autophagy effect on immune cell metabolism. This will be a valuable resource for researchers, oncologists, graduate students, and members of the biomedical field who are interested in learning more about the interaction between autophagy and cancer metabolism. - Presents valuable and updated information on the mechanisms of autophagy in cancer metabolism - Discusses the various metabolic pathways linked with autophagy that can be a major target for chemotherapeutic strategies - Explains how autophagy supports tumor growth by activating metabolic phenotypes in cancer cells and the therapeutic interventions available to halt the process

Download or read book Ryan s Retina E Book written by SriniVas R. Sadda and published by Elsevier Health Sciences. This book was released on 2022-04-13 with total page 2949 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through six outstanding and award-winning editions, Ryan's Retina has offered unsurpassed coverage of this complex subspecialty—everything from basic science through the latest research, therapeutics, technology, and surgical techniques. The fully revised 7th Edition, edited by Drs. SriniVas R. Sadda, Andrew P. Schachat, Charles P. Wilkinson, David R. Hinton, Peter Wiedemann, K. Bailey Freund, and David Sarraf, continues the tradition of excellence, balancing the latest scientific research and clinical correlations and covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. More than 300 global contributors share their knowledge and expertise to create the most comprehensive reference available on retina today. - Features sweeping content updates, including new insights into the fundamental pathogenic mechanisms of age-related macular degeneration, advances in imaging including OCT angiography and intraoperative OCT, new therapeutics for retinal vascular disease and AMD, novel immune-based therapies for uveitis, and the latest in instrumentation and techniques for vitreo-retinal surgery. - Includes five new chapters covering Artificial Intelligence and Advanced Imaging Analysis, Pachychoroid Disease and Its Association with Polypoidal Choroidal Vasculopathy, Retinal Manifestations of Neurodegeneration, Microbiome and Retinal Disease, and OCT-Angiography. - Includes more than 50 video clips (35 new to this edition) highlighting the latest surgical techniques, imaging guidance, and coverage of complications of vitreoretinal surgery. New videos cover Scleral Inlay for Recurrent Optic Nerve Pit Masculopathy, Trauma with Contact Lens, Recurrent Retinal Detachment due to PVR, Asteroid Hyalosis, and many more. - Contains more than 2,000 high-quality images (700 new to this edition) including anatomical illustrations, clinical and surgical photographs, diagnostic imaging, decision trees, and graphs. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.