Download or read book Atypical Diabetes written by Boris Draznin and published by American Diabetes Association. This book was released on 2018-05-01 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the vast majority of diabetes cases (type 1 and type 2) are polygenic diseases, research, funded by the American Diabetes Association, has found that some forms of diabetes, distinct from type 1 or type 2 diabetes, are caused by single gene mutations. It has been estimated that these monogenic forms of diabetes account for up to five percent of all diabetes cases. In addition to monogenic diabetes, there are other atypical causes of diabetes, including: genetic defects in insulin action; diseases of the exocrine pancreas; and endocrinopathies. Given recent advances in our understanding of sub-types of diabetes, the time has come for a book on how to correctly diagnose and treat patients with atypical forms of this disorder. The book will be divided into three parts, each exploring distinct categories of atypical diabetes. Part I: Monogenic Diabetes: Genetic Defects of β-cell development and function; Part II: Insulin resistance, genetic defects in insulin action, and diseases of exocrine pancreas; Part III: Endocrinopathies, Immune-mediated diabetes, Diabetes of Unknown cause, and Other genetic syndromes sometimes associated with diabetes.
Download or read book Syndromic Atypical diabetes mellitus and deletion 16q24 2 written by Lauriane Le Collen and published by . This book was released on 2019 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: We report the case of a patient with several malformations including lymphedema distichiasis syndrome (LDS), intellectual disability, atypical diabetes and obesity, carrying a heterozygous deletion located in 16q24.2 encompassing 693 kb. Diabetes occurred at an early age but stood out from type 1 diabetes by several aspects (negative antibodies, none acidosis, no pancreas atrophy). Surprisingly, metformin® then GLP1 receptor agonist treatment allowed an important weight loss with a controlled glycemia. To better understand the relationship between the genomic and the clinical features of our patient, we focused on the FOXC2 gene, 550kb distant to this region, after excluding monogenic diabetes and syndromic obesity by whole exome sequencing. Indeed, this gene is known to be responsible for LDS. Previous studies reported new activating mutation with LDS onset. Using the RT qPCR, we showed FOXC2 overexpression in our patient. It could be the consequence of a deletion of long range regulatory element and may modify the structure of topologically associated domains. The atypical diabetes and the polymalformative syndrome (distichiasis, intellectual disability, kidney and uterine malformations, dental malposition) of our patient may be the result of haploinsufficiency of the deleted genes in 16q24.2 interval and by the disruption of FOXC2 regulation. JPH3, is a gene located in the deleted region, and codes for junctophilin-3 (components of junctional complexe). It seems to be involved in decreased glucose-stimulated insulin secretion to mice model. Further clinical and molecular studies in patient cohort are needed to better assess a possible relationship between FOXC2 expression and atypical diabetes. Moreover, JPH3 dysfunction might be involved in human diabetes.
Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Genetics and Characteristics of Atypical Diabetes Mellitus written by Adele Kennedy and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Greater Age and Morbidity at Diagnosis of Atypical Diabetes Compared to Immune mediated Type 1 Diabetes in Haitian Youth written by Jean Baptiste Eddy and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Greater Age and Morbidity at Diagnosis of Atypical Diabetes Compared to Immune Mediated Type 1 Diabetes (T1D) in Haitian Youth.Aim: Longstanding clinical experience suggests both atypical and immune mediated forms of diabetes exist among Haitian youth, but T1D associated autoantibody (AAb) testing is not routinely available. This study assessed phenotypes (metabolic, immunologic, and genetic) associated with atypical diabetes and T1D in Haitian youth at/soon after diagnosis. Methods: 91 subjects aged
Download or read book Diabetes in Practice written by Boris Draznin and published by American Diabetes Association. This book was released on 2022-10-26 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes clinical practice is a life-long learning experience, and the insights presented in Diabetes in Practice will facilitate a deeper knowledge of the complex nature of diabetes and its comorbidities for physicians, nurse practitioners, registered dietitians, diabetes educators, and students. Diabetes in Practice offers a deep look into years of the professional practice of clinical diabetes. The 49 case studies Boris Draznin, MD, PhD, has assembled cover a wide array of diabetes cases involving atypical presentations to those addressing ketoacidosis and hypoglycemia, continuous glucose monitoring and insulin pumps, and diabetes co-occurring with cancer and autoimmune conditions. Each case study includes expert review from long-term diabetes practitioners to help you in your daily interactions with patients and enhance your understanding of diabetes diagnosis and treatment challenges.
Download or read book Intensive Diabetes Management 7th Edition written by Devin Steenkamp and published by American Diabetes Association. This book was released on 2022-10-26 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intensive diabetes management is the process by which blood glucose levels are closely controlled using multiple daily insulin injections or an insulin pump. Intensive Diabetes Management is geared toward the health care practitioner who wants to implement this method in his or her patients. Now in its seventh edition, this authoritative text includes the latest advances in research and therapy. The data, guidelines, and procedures reflect the latest positions of the American Diabetes Association's standards of care. Although difficult to maintain, intensive diabetes management has proven very effective and is now the rule, rather than the exception, in diabetes care. People who use this method of diabetes management must be closely aligned with their health care team and highly motivated because it not only requires close scrutiny of blood glucose levels, but also constant monitoring of food intake and medication dosage, among other things. Virtually all patients with type 1 or type 2 diabetes can improve their glycemic control and overall health through intensive diabetes management. Intensive Diabetes Management emphasizes a team approach to patient care and offers guidance in helping patients move toward treatment goals appropriate for their individual skills and medical condition. Individual sections address all of the key topics in intensive diabetes management, including rationale/physiological basis, team approach, education, pyschosocial issues, patient selection/goals of therapy, insulin regimens, insulin pump therapy, monitoring, and nutrition management.
Download or read book The Epidemiology of Diabetes Mellitus written by Jean Marie Ekoé and published by John Wiley & Sons. This book was released on 2008-09-15 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this book gained recognition as the definitive textbook of diabetes epidemiology. The second edition builds on this success, gathering recent information on international trends and data for diabetes mellitus. In particular, the book highlights the dramatic rise of Type 2 diabetes in children, adolescents and the elderly throughout the world. One new section features prevention and screening of both Type1 and Type 2 diabetes. Other new chapters cover the epidemiology of obesity and the impact of nutrition, and review available guidelines for better worldwide glycemic control. Future challenges, including the effects of antipsychotic treatment and HIV infection and therapy on diabetes, are also addressed. All chapters have been completely revised and updated, covering: definitions, classification and risk factors for diabetes new evidence for screening and prevention of Type 1 and Type 2 diabetes epidemiology of complications and associated risk factors economic aspects: the direct and indirect costs of diabetes. The Epidemiology of Diabetes Mellitus fills the need for a current compendium of diabetes epidemiology in the tradition of the first monumental text of the late Kelly West. It is essential reading for general practitioners, diabetologists, clinical endocrinologists, cardiologists, epidemiologists, nurses, dieticians, and other diabetes care providers, as well as health care decision makers.
Download or read book Psychosocial Care for People with Diabetes written by Deborah Young-Hyman and published by American Diabetes Association. This book was released on 2012-12-25 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychosocial Care for People with Diabetes describes the major psychosocial issues which impact living with and self-management of diabetes and its related diseases, and provides treatment recommendations based on proven interventions and expert opinion. The book is comprehensive and provides the practitioner with guidelines to access and prescribe treatment for psychosocial problems commonly associated with living with diabetes.
Download or read book Clinical Dilemmas in Diabetes written by Adrian Vella and published by Wiley-Blackwell. This book was released on 2011-04-18 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Dilemmas in Diabetes provides evidence-based clinical guidance on the most common and problematic areas of concern encountered in diagnosing, treating and managing patients with diabetes. Each chapter is highly topical and has been selected due to current interest, specific recent developments, and areas of controversy. This valuable guide provides assistance in managing the life-long treatment of diabetes and the complications that often develop in patients. Clinical Dilemmas in Diabetes guides the medical team in their decision-making, particularly when there are conflicts in the treatment for the disease and the complications. Part of the Clinical Dilemmas series, the well-focused chapter structure allows for quick retrieval of information, and each opens with a “Learning Points” box to aid easy assimilation of the main issues. With a leading team of contributors and editors, Professor Robert A. Rizza is the immediate Past-President of the American Diabetes Association. This book is perfect for use on the wards and clinics as well as for self-study by diabetologists, diabetes specialist nurses, endocrinologists, GPs and cardiologists.
Download or read book Clinical Handbook of Complex and Atypical Eating Disorders written by Leslie K. Anderson and published by Oxford University Press. This book was released on 2018 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Handbook of Complex and Atypical Eating Disorders brings together into one comprehensive resource what is known about an array of complicating factors for patients with ED, serving as an accessible introduction to each of the comorbidities and symptom presentations highlighted in the volume.
Download or read book Case Studies in Diabetes written by D John Betteridge and published by CRC Press. This book was released on 2023-04-14 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the increasing incidence of Type 2 diabetes in the adult population and the realization that this is a vascular disease and a major coronary risk factor, Professor Betteridge has chosen fifty diabetologists to contribute a case which has had an effect on their clinical practice. Both Types 1 and 2 diabetes are included, along with other forms of diabetes, eg gestational. Each case is presented in the same format. The various cases are informative and educational and should provide the reader with a sounder knowledge of patient and disease types.
Download or read book Human Behavior Learning and the Developing Brain written by Donna Coch and published by Guilford Press. This book was released on 2010-06-15 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together leading authorities from multiple disciplines to examine the relationship between brain development and behavior in typically developing children. Presented are innovative cross-sectional and longitudinal studies that shed light on brain–behavior connections in infancy and toddlerhood through adolescence. Chapters explore the complex interplay of neurobiological and environmental influences in the development of memory, language, reading, inhibitory control, and other core aspects of cognitive, emotional, and social functioning. Throughout, the volume gives particular attention to what the research reveals about ways to support learning and healthy development in all children. Illustrations include four pages in full color.
Download or read book Diabetic Foot Syndrome written by Dirk Hochlenert and published by Springer. This book was released on 2018-09-04 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a clear and integrated guide to the diagnostic pathways and therapeutic options available for the treatment of diabetic foot syndrome. The link between the location of the lesion and its potential causes are discussed in relation to its diagnosis, biomechanics, treatment and prognosis. Chapters covering interdigital lesions, the lateral side of the foot, torsion of the hallux, and the charcot foot are included. Diabetic Foot Syndrome: From Entity to Therapy aims to facilitate interdisciplinary understanding and is relevant to endocrinologists, as well as vascular and orthopedic surgeons.
Download or read book Diabetes and the Kidney written by Kar Neng Lai and published by Karger Medical and Scientific Publishers. This book was released on 2011 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive update on clinical and basic aspects of diabetic nephropathy Caused by an epidemic increase in obesity and diabetes and metabolic syndromes, diabetic nephropathy has become a leading cause of end-stage renal disease in many developed countries. The publication at hand provides a concise overview of the current state of clinical and basic research in the field. It starts with a summary of the epidemiology and genetics of diabetic nephropathy in different ethnic groups, followed by a review of its clinical manifestation, the link with the metabolic syndrome and obesity, and the pathology of diabetic nephropathy. Building on this basis, the latest findings on pathogenetic, epigenetic and inflammatory mechanisms are presented. The publication also looks at advances in the areas of tubulopathy and the kallikrein-kinin system as well as at the latest animal models and the role of lipoproteins and proteomics. This is followed by a discussion of promising therapeutic approaches such as experimental anti-fibrotic strategies, stem cell therapy and pancreatic transplantation; expert reviews on the emerging entity of new onset diabetes after transplantation and the preventive strategies for diabetic nephropathy conclude the material presented. Written by a panel of leading international experts, this book is highly recommended for nephrologists, diabetologists, internist, transplant physicians, scientists, geneticists, epidemiologists and stem cell biologists working in the field of diabetic nephropathy.
Download or read book Diabetes in Practice written by Boris Draznin and published by . This book was released on 2021-08-10 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes in Practice offers a detailed look into years of professional practice in clinical diabetes. The 49 case studies Boris Draznin, MD, PhD, has assembled cover a wide array of diabetes cases involving atypical presentations to those addressing ketoacidosis and hypoglycemia, continuous glucose monitoring and insulin pumps, and diabetes co-occurring with cancer and autoimmune conditions. Each case study includes expert review from long-term diabetes practitioners.
Download or read book Studies Concerning Glycosuria and Diabetes written by Frederick Madison Allen and published by . This book was released on 1913 with total page 1444 pages. Available in PDF, EPUB and Kindle. Book excerpt:
