Download or read book Atypical Breast Proliferative Lesions and Benign Breast Disease written by Farin Amersi and published by Springer. This book was released on 2018-09-27 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of atypical breast lesions continues to evolve. There is considerable controversy as to whether these entities represent risk factors for future breast cancer or whether they are instead precursor lesions. A better understanding of the prognostic and therapeutic implications of each of these lesions is important for assessing subsequent breast cancer risk. Risk assessment tools are available for screening high risk patients and understanding the utility and limitations of these tools is important for all clinicians involved in the care of patients. There have been significant advances in breast cancer screening in the last several year including breast tomosynthesis, automated breast ultrasound, molecular imaging, as well as accelerated breast MRI protocols. This has raised the question: Do women at risk for breast cancer need additional breast cancer screening using these newer imaging modalities? In addition, with these advances in imaging, can women with atypical proliferative lesions be observed rather than undergoing surgical excision as some suggest? The role of observation, surgical excision and even prophylactic mastectomy in women with atypical proliferative lesions continues to be debated; however there is data that can guide physicians in the management of these patients. Pleomorphic Lobular carcinoma in-situ (PLCIS) is a distinct pathological entity within LCIS and there is no consensus regarding surgical margins or the need for adjuvant treatment to prevent recurrence. Recently, ductal carcinoma in-situ (DCIS) has been the subject of much controversy: is it truly a cancer or is it instead a precursor lesion. The traditional management of DCIS with lumpectomy and radiation is now being debated and recent data demonstrates that low grade DCIS can be managed with observation. Clinical trials are now accruing patients with low and intermediate grade DCIS to observation and close surveillance, and not surgical excision. Finally, new guidelines for chemoprevention with the use of tamoxifen and raloxifen for women with atypical proliferative lesions, LCIS, PLCIS, and DCIS are available and should be discussed as an option when guiding management of these patients. This book will provide a comprehensive review of this field and will serve as a valuable resource for clinicians, general surgeons, breast surgeons and surgical oncologists, as well as researchers with an interest in the management of atypical breast lesions. The book will review new data about breast cancer, risk factors for breast cancer, pathological features unique to each entity, the characteristic findings on imaging, risk stratification for genetic testing, as well as the current evidence-based management of each of these breast lesions. Our text will provide assessment tools for risk prediction of breast cancer. We will provide data on the current imaging modalities, as well as advanced screening options available for diagnosis and following these patients. Current management of many of these lesions continues to be controversial in regard to observation with close surveillance versus the need for surgical excision of these lesions based on future risk or whether these lesions are precursor lesion. For ductal carcinoma in-situ, the debate continues in regards to whether this disease entity is a precursor lesion that can be managed with observation or hormonal therapy, or is DCIS cancer and treated with lumpectomy and radiation. Several studies have been published where patients are managed with observation and treatment with hormonal therapy before surgical management. New trials have already begun accruing patients with low to intermediate grade DCIS where patients will be managed with observation versus hormonal therapy only. Management of DCIS continues to evolve and current management will be discussed This text will provide a concise but comprehensive summary of the current management of patients with atypical breast proliferative lesions and some benign breast lesions and will help guided management of these patients. All chapters in this text will be written by experts in the field in each of these disease entities. They will all include the most up to date research and clinical information to enhance our understanding and treatment of patients.
Download or read book Atypical Breast Proliferative Lesions and Benign Breast Disease written by Farin Amersi and published by Springer. This book was released on 2019-01-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of atypical breast lesions continues to evolve. There is considerable controversy as to whether these entities represent risk factors for future breast cancer or whether they are instead precursor lesions. A better understanding of the prognostic and therapeutic implications of each of these lesions is important for assessing subsequent breast cancer risk. Risk assessment tools are available for screening high risk patients and understanding the utility and limitations of these tools is important for all clinicians involved in the care of patients. There have been significant advances in breast cancer screening in the last several year including breast tomosynthesis, automated breast ultrasound, molecular imaging, as well as accelerated breast MRI protocols. This has raised the question: Do women at risk for breast cancer need additional breast cancer screening using these newer imaging modalities? In addition, with these advances in imaging, can women with atypical proliferative lesions be observed rather than undergoing surgical excision as some suggest? The role of observation, surgical excision and even prophylactic mastectomy in women with atypical proliferative lesions continues to be debated; however there is data that can guide physicians in the management of these patients. Pleomorphic Lobular carcinoma in-situ (PLCIS) is a distinct pathological entity within LCIS and there is no consensus regarding surgical margins or the need for adjuvant treatment to prevent recurrence. Recently, ductal carcinoma in-situ (DCIS) has been the subject of much controversy: is it truly a cancer or is it instead a precursor lesion. The traditional management of DCIS with lumpectomy and radiation is now being debated and recent data demonstrates that low grade DCIS can be managed with observation. Clinical trials are now accruing patients with low and intermediate grade DCIS to observation and close surveillance, and not surgical excision. Finally, new guidelines for chemoprevention with the use of tamoxifen and raloxifen for women with atypical proliferative lesions, LCIS, PLCIS, and DCIS are available and should be discussed as an option when guiding management of these patients. This book will provide a comprehensive review of this field and will serve as a valuable resource for clinicians, general surgeons, breast surgeons and surgical oncologists, as well as researchers with an interest in the management of atypical breast lesions. The book will review new data about breast cancer, risk factors for breast cancer, pathological features unique to each entity, the characteristic findings on imaging, risk stratification for genetic testing, as well as the current evidence-based management of each of these breast lesions. Our text will provide assessment tools for risk prediction of breast cancer. We will provide data on the current imaging modalities, as well as advanced screening options available for diagnosis and following these patients. Current management of many of these lesions continues to be controversial in regard to observation with close surveillance versus the need for surgical excision of these lesions based on future risk or whether these lesions are precursor lesion. For ductal carcinoma in-situ, the debate continues in regards to whether this disease entity is a precursor lesion that can be managed with observation or hormonal therapy, or is DCIS cancer and treated with lumpectomy and radiation. Several studies have been published where patients are managed with observation and treatment with hormonal therapy before surgical management. New trials have already begun accruing patients with low to intermediate grade DCIS where patients will be managed with observation versus hormonal therapy only. Management of DCIS continues to evolve and current management will be discussed This text will provide a concise but comprehensive summary of the current management of patients with atypical breast proliferative lesions and some benign breast lesions and will help guided management of these patients. All chapters in this text will be written by experts in the field in each of these disease entities. They will all include the most up to date research and clinical information to enhance our understanding and treatment of patients.
Download or read book Benign Breast Diseases written by Catherine N. Chinyama and published by Springer Science & Business Media. This book was released on 2013-12-20 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this book has been extensively revised and updated. There has been a lot of scientific advances in the radiology, pathology and risk assessment of benign breast lesions since the publication of the first edition. The first edition concentrated on screen-detected lesions, which has been rectified. New symptomatic and screen-detected lesions are discussed in the second edition and include: mastitis and breast abscess, idiopathic granulomatous mastitis, diabetic mastopathy, phyllodes tumour, gynaecomastia and pseudoangiomatous stromal hyperplasia. The chapters on columnar cell lesions and mucocele-like lesions have been extensively updated. Where applicable, genetic analysis of the benign lesions which in breast cancer is becoming part of personalised medicine has been included. The book includes detailed analysis of the main models such as the Gail Model used to assess the subsequent risk of breast cancer in individuals. The current trend in the management of all cancers is preventative. Screening mammography detects early curable cancers as well as indeterminate lesions. These indeterminate mammographic lesions are invariably pathologically benign. The author collated important benign lesions and based on peer-reviewed publications documented the relative risk of subsequent cancer to allow the patient and the clinician to institute preventative measures where possible. This book therefore will be an essential part of multidisciplinary management of patients with symptomatic and screen-detected benign breast lesions.
Download or read book Breast Cytopathology written by M. Pinamonti and published by Karger Medical and Scientific Publishers. This book was released on 2017-11-27 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cytopathology is a field characterized by practicality and diagnostic efficacy. This book focuses mainly on morphology, with helpful hints for recognizing benign lesions and the main features of malignancy. It reviews specific features of various lesions and the consequences of the diagnosis for the management of the patient. Each chapter contains high-quality cytology images accompanying the descriptions, including comparison images to distinguish the most important morphological features and to help in the differential diagnosis. Fine needle aspiration cytology (FNAC) sampling and preparation technique, fixation, staining, and principles of its interpretation are covered. Immunocytochemistry and ancillary techniques are outlined, as well as the main clinical and radiological features of breast lesions, and the cytological diagnostics of axillary lymph nodes. This publication will be of great use to medical practitioners in their first approach to breast cytopathology, as well as to pathologists and cytotechnicians with little to moderate experience in the field.
Download or read book Preneoplasia of the Breast written by Werner Boecker and published by Fischer Gustav Verlag GmbH & Company KG. This book was released on 2006 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preneoplasia of the Breast: presents the latest developments in the field, emphasizing cell-biological processes and depicting how they contribute to a better understanding and diagnosis of benign and malignant proliferative breast disease. is outstanding in its design, depicting over 540 full-color photomicrographs of conventional hematoxylin-eosin and immunohistochemical stainings. provides conceptual diagrams for a clearer understanding of the associated cellular processes. details the relevant radiologic, clinical and therapeutic background, clearly depicting how the pathologist can contribute to improved treatment of breast disease. contains contributions from renowned European and American pathologists and clinicians.
Download or read book Breast Cancer and its Precursor Lesions written by Patricia A. Thomas and published by Springer Science & Business Media. This book was released on 2010-10-20 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rather than an exhaustive review of all the pathologic conditions of the female breast, Breast Cancer and its Precursor Lesions focuses on the current knowledge, understanding and issues related to breast cancer and its benign lesions that are associated with an increased risk for the subsequent development of cancer. This book targets the language, diagnostic terms and critical communication that must take place between primary care physicians, breast surgeons, oncologists, and general surgical pathologists interested in the pathologist’s perspective on these important diseases. The volume also reviews the current terminology and how to read or write meaningful pathology reports on these entities, the foils and nuances of the pathology and implications for management, and up to date issues in genomics and proteomics of these conditions. The text is succinct, fully informative, and written in “plain language”. All chapters are presented in a uniform fashion, and supplemented by high-quality illustrations and tables. Breast Cancer and its Precursor Lesions will be of great value to pathologists as well as primary care physicians, breast surgeons, and oncologists for understanding breast pathology and its implications for management.
Download or read book Breast Cytohistology written by Joan Cangiarella and published by Cambridge University Press. This book was released on 2013-09-12 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each volume in this richly illustrated series, published in association with the Papanicolaou Society of Cytopathology, provides an organ-based approach to the cytological and histological diagnosis of small tissue samples. Benign, pre-malignant and malignant entities are presented in a well-organized and standardized format, with high-resolution color photomicrographs, tables, and lists of key specific morphologic criteria. Example vignettes allow the reader to assimilate the diagnostic principles in a case-based format. This volume provides comprehensive coverage of both surgical pathology and cytopathology of breast lesions. With a focus on malignant tumors, the full spectrum of inflammatory disorders, benign lesions, and hyperplasias are also covered in detail. Advantages and disadvantages of aspiration and core biopsy are discussed, as well as ancillary testing such as hormonal and molecular markers. With over 200 printed photomicrographs and a DVD-ROM offering all images in a downloadable format, this is an important resource for all anatomic pathologists.
Download or read book Breast Pathology in Clinical Practice written by Sami Shousha and published by Springer Nature. This book was released on 2020-07-01 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise, step-by-step guide to accurate microscopic diagnosis for clinicians who deal with patients with breast lesions. The emphasis is on a practical approach to dealing with breast biopsies and reaching a diagnosis. It outlines the procedures used for the microscopic diagnosis of various breast lesions and the significance of the nomenclature and terms used in pathology reports, including those dealing with uncommon or rare lesions. Ample illustrations of the lesions discussed are included, particularly those dealing with uncommon and border-line lesions. There is a special emphasis on breast cancer and on the fact that not all breast cancers are the same. The different ways by which breast cancers are classified are discussed including recent classifications which lead to personalized therapy. The book is aimed at pathologists of all grades who deal with breast biopsies including those in training. It would be also useful for practicing and trainee surgeons and oncologists as well as other health professionals dealing with patients with breast diseases and scientists carrying out research on breast problems.
Download or read book Breast Cancer Screening and Diagnosis written by Mahesh K Shetty and published by Springer. This book was released on 2014-09-19 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the current trends and practices in breast imaging. Topics include mammographic interpretation; breast ultrasound; breast MRI; management of the symptomatic breast in young, pregnant and lactating women; breast intervention with imaging pathological correlation; the postoperative breast and current and emerging technologies in breast imaging. It emphasizes the importance of fostering a multidisciplinary approach in the diagnosis and treatment of breast diseases. Featuring more than 800 high-resolution images and showcasing contributions from leading authorities in the screening, diagnosis and management of the breast cancer patient, Breast Cancer Screening and Diagnosis is a valuable resource for radiologists, oncologists and surgeons.
Download or read book Diseases of the Breast written by Jay R. Harris and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 3432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, and now in full color throughout, the Fourth Edition of this definitive reference is a must for all clinicians who treat breast diseases. Leading experts summarize the current knowledge of breast diseases, including their clinical features, management, underlying biologies, and epidemiologies. In addition to complete coverage of malignant breast diseases, benign diseases are discussed in relation to subsequent breast cancer development. The book reviews all major clinical trials and summarizes the information they provide on early detection and management of breast cancer. Close attention is also given to the increasing importance of molecular biology and genetics in this field. This edition features more than thirty new contributors, fourteen new or completely rewritten chapters, and more clinically oriented chapters. A companion Website will offer the fully searchable text and an image bank. Also included with this edition is the Anatomical Chart Company's Breast Anatomy and Disorders Pocket Guide. This durable, portable folding pocket guide provides a visual and textual overview of breast anatomy, disorders, and breast self-examination. With a write-on, wipe-off laminated surface, this guide is perfect for the on-the-go practitioner to show patients, caregivers, and families.
Download or read book Progress in Surgical Pathology written by Cecilia M. Fenoglio-Preiser and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series of volumes Progress in Surgical Pathology was conceived in an attempt to honor the 70th birthday of Dr. Raffaele Lattes. The original vol umes were the result of an initial call for papers dedicated to progress in the field of surgical pathology with contributors from all over the world. The pa pers published in these volumes have represented examples of classical clin ical pathologic correlations within the discipline of surgical pathology; other papers reflect the work being done at the interface between classical diagnos tic surgical pathology and research in the realm of immunology, molecular biology, cell biology, etc. These papers illustrate what is possible utilizing all of the advances made in basic biology, while remembering that the patholo gist remains an essential, crucial figure in the analysis of tissues, both with respect to their diagnosis as weil as the analysis of the dynamic interactions between cells. There have also been papers that may be characterized as philosophical or historical, which Iook at aspects of surgical pathology in a unique way. Five volumes have been published since 1980. The last of these was pub lished in 1983. For those of you who have been our loyal readers, you may wonder why there has been a gap in the publication of these volumes. This has been due to reorganization both among ourselves as weil as with the pub lisher.
Download or read book Rosen s Breast Pathology written by Syed A. Hoda and published by Lippincott Williams & Wilkins. This book was released on 2020-10-23 with total page 3238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Widely recognized as the gold standard reference in the field, Rosen’s Breast Pathology provides comprehensive, up-to-date information on diseases of the breast from renowned experts at four leading medical centers, masterfully edited by Dr. Paul P. Rosen. The revised fifth edition covers the latest advances in immunohistochemical, pathobiological, and molecular aspects of benign and malignant breast diseases, helping you reach an accurate diagnosis with confidence. It’s an ideal reference for all physicians and medical personnel who require a thorough knowledge of breast pathology, including pathologists, surgeons, oncologists, radiologists, and radiation oncologists.
Download or read book Biopsy Interpretation of the Breast written by Stuart J. Schnitt and published by Lippincott Williams & Wilkins. This book was released on 2012-10-08 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide for the diagnostic surgical pathologist, this new edition of Biopsy Interpretation of the Breast presents the diverse spectrum of pathologic alterations that occur in the breast in a manner analogous to that in which they are encountered in daily practice. Lesions are grouped together according to their histologic patterns rather than by the traditional benign-malignant categorization in order to simulate the way pathologists face these lesions as they examine microscopic slides on a daily basis. The role of adjunctive studies in solving diagnostic problems in breast pathology is emphasized where appropriate. In addition, the clinical significance and impact on patient management of the various diagnoses are discussed and key clinical and management points highlighted.
Download or read book Women at High Risk to Breast Cancer written by B.A. Stoll and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reprint of the 1989 edition of this book has been made necessary by continuing demand after rapid exhaustion of the first printing. In the two years since its appearance, there has been relatively little expansion of knowledge on this topic, and its massive accumulation of references still remains an authoritative guide in the difficult task of developing a national breast cancer prevention model. At the same time, its thesis has been sharpened by the publication of a companion volume Approaches to Breast Cancer Prevention (Kluwer, 1991) similarly edited byrne. Breast cancer is on the increase throughout the Western world where it is a major source of anxiety among women. The disease is also becoming more frequent in Asian and South American countries where once it was relatively uncommon. Multiple fac tors are suspected of promoting the disease and the increasing risk is attributed to recent changes in life-style and diet. This book is intended to provide an authorita tive and balanced survey of the latest research into the genetic, familial, hormonal, reproductive, nutritional, social and geographic factors known to be associated with an increased predisposition to the disease.
Download or read book Smoking and Hormone related Disorders written by Nicholas J. Wald and published by . This book was released on 1990 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of the hormone disorders associated with smoking are of relatively recent interest. This book provides summaries of the present status of research into the effects of smoking, the apparent protection offered against certain diseases, and suggested ways of predicting trends of disease patterns. Not all the disorders discussed are adverse effects of smoking, providing impetus for developing non-tobacco methods of disease prevention.
Download or read book Atlas of Differential Diagnosis in Breast Pathology written by Puay Hoon Tan and published by Springer. This book was released on 2017-04-26 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas illustrates the range of breast lesions with detailed correlation of gross and microscopic features. Where relevant, radiological images are incorporated. A description of normal, developmental and physiological breast morphology will serve as introduction to the main content of this atlas. Classification of tumors is based on the latest World Health Organization Classification of Tumors of the Breast, 4th edition, 2012. As immunohistochemistry is a key adjunctive tool in the workup of breast lesions as well as used in prognostic evaluation of breast cancers, appropriate examples are interspersed among the lesions where pertinent.
Download or read book The Breast written by Christopher William Elston and published by . This book was released on 1998 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference features comprehensive, practical guidance on the pathological aspects of breast disease. With a multidisciplinary approach, it examines traditional histopathological characteristics while also emphasizing the latest advances in molecular biology and genetics, and the role of newer techniques such as immunocytochemistry. Abundantly illustrated! Limited to the United States, Central America, South America, and the Caribbean.
