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Book Assisted Reproductive Technology and Adverse Perinatal Outcomes

Download or read book Assisted Reproductive Technology and Adverse Perinatal Outcomes written by Galit Levi Dunietz and published by . This book was released on 2015 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Infertility  Assisted Reproductive Technologies and Hormone Assays

Download or read book Infertility Assisted Reproductive Technologies and Hormone Assays written by Dhastagir Sultan Sheriff and published by BoD – Books on Demand. This book was released on 2019-07-17 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infertility is a major public health concern and medical condition that afflicts millions globally. As such, many people seek reproductive care with the goal of receiving a proper diagnosis and a successful outcome using assisted reproductive technology (ART). Infertility: Assisted Methods of Reproduction and Hormonal Assays provides an overview of ART methods and discusses recent trends in the field. Chapters cover an array of topics including diagnosis of infertility using hormonal assays, adverse outcomes of ART, oocyte donation, cryopreservation of oocytes and embryos and psychosocial care.

Book Assisted Reproductive Technology and Adverse Child Health Outcomes

Download or read book Assisted Reproductive Technology and Adverse Child Health Outcomes written by Michele Hansen and published by . This book was released on 2013 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: [Truncated abstract] Background and Aims: Assisted Reproductive Technologies (ART) have undergone rapid development since the birth of the first IVF baby, in 1978. Studies evaluating the safety of ART have lagged far behind rapidly changing laboratory techniques and are largely limited to short term health outcomes that can be assessed at or close to the time of birth. Western Australia (WA) is the only State in Australia with a statutory Reproductive Technology Register (RTR), and one of only a few places in the world with the infrastructure for routine population based data linkage. Linkage of data from the RTR to other health registers allows for long term follow up of ART births and comparison of health outcomes with all other non ART births in the population. The publication of an earlier study using data from these registers showed that Western Australian ART infants had a two fold increased risk of birth defects compared with non ART infants. These results generated much discussion in the ART literature with clinicians stating that national ART registers reported much lower birth defect prevalence rates and that other studies had not found an increased birth defect risk following ART. The main aims of this thesis were to systematically review and pool the results of the literature comparing birth defects in ART and non ART infants; to compare the prevalence of birth defects in WA born ART infants identified through record linkage to the WA Register of Developmental Anomalies with the prevalence of birth defects reported to the national Australian ART Register by WA IVF clinicians; and finally, to compare the prevalence of birth defects, perinatal outcomes and hospital admission in the total population of ART and non ART births in Western Australia from 1994 to 2002. Methods: Systematic review of the ART birth defects literature. Systematic review of the ART literature was carried out in March 2003 and again, almost 10 years later, in September 2012. I specifically searched for papers that compared birth defects in IVF or ICSI infants and a non ART comparison group. Pooled estimates of birth defect risk were calculated for all studies and for studies of singletons and multiples separately, as well as for a range of other important subgroups. Comparison of birth defect ascertainment based on a national ART Register with record linkage to a dedicated birth defects register. Birth defect prevalence in WA born ART infants was compared when the national ART register was used as a source of birth defects data and when record linkage of the statutory RTR with the WA Register of Developmental Anomalies (WARDA) was used to identify birth defects. Birth defects, perinatal outcome and hospital admission in ART and non ART children in Western Australia. All ART and non ART births in Western Australia during the study period were identified using record linkage of the Reproductive Technology Register, the Midwives Notification System, the WARDA and the Hospital Morbidity System. Birth defects diagnosed in terminations of pregnancy and up to the age of six years were compared in ART and non ART children. Perinatal outcomes and hospital admission up to three years of age were also compared. The results were analysed separately for singletons and twins...

Book Medically Assisted Reproduction and the Risk of Adverse Perinatal Outcomes

Download or read book Medically Assisted Reproduction and the Risk of Adverse Perinatal Outcomes written by Anick B√©rard and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 5 million children have been born through in vitro fertilization (IVF) across the world. IVF is only one of the many methods of assisted reproduction, which can be used to achieve pregnancy in the context of infertility or subfertility. Since the birth of the first IVF child, Louise Brown, in 1978, a number of researchers have started to study the various impacts of the conception through these methods, on both mothers and children. A growing body of evidence suggests that conception through medically assisted reproduction (MAR) is not without risk. Given that MAR is relatively new and that our look back period is short, there is limited evidence on the risks associated to these procedures, both for the mother and the child. In this chapter, we aim to explore the association between MARs and adverse perinatal outcomes specifically. We will first provide you with an overview of the prevalence and trends of use of these methods around the world, and then delve into the associations between MARs and the risk of perinatal outcomes, namely prematurity, being born with low birth weight and/or small for gestational age, and lastly the impact of MARs on cognitive functions including cerebral palsy, behavioral problems, and autism, which are identified later in the child,Äôs life.

Book Pregnancy and Birth After Assisted Reproductive Technologies

Download or read book Pregnancy and Birth After Assisted Reproductive Technologies written by Michael Ludwig and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within 10 chapters this book addresses the whole gamut of questions that may arise in the context of pregnancy resulting from assisted reproduction. Incidence of abortion, extrauterine pregnancy or chromosomal abnormalities, pregnancy complications, problems regarding mode of delivery and the health status of children at birth are covered as well as the further development of the children and the social structure of the families. Topics such as follow-up of families in lesbian relationships and following gamete donations are also discussed.

Book Risk of Adverse Perinatal Outcomes in Dizygotic Twins After IVF Pregnancies

Download or read book Risk of Adverse Perinatal Outcomes in Dizygotic Twins After IVF Pregnancies written by Fatima J. Baar and published by . This book was released on 2011 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background: Since the birth of the first test tube baby, 25 years ago, more than three million babies have been born using assisted reproductive technologies (ART). Twin births by way of ART represent 20-30% of U.S. and European births, as compared to only 1% of natural births. The purpose of this study is to investigate the risk of adverse perinatal outcomes in ART dizigotic twins, compared with non-ART twins. Method: A review of the medical literature available in Pub Med, EBM review, the National Clinical Trials Registry and CINAHL databases. The search was limited to English language sources between 2000 and 2010. Three cohort studies were identified for the final systematic review. The GRADE tool was used to evaluate the evidence. Results: The three cohort studies found no higher risk of low birth weight in ART twins after stratification for maternal age and parity. Birth weight discordance and mortality rates showed similar result as low birth weight. Two of the studies found an increased risk of hospitalization and neonatal intensive care unit admissions and maintained this result after stratification for maternal factors. One study found a higher risk of prematurity in twins conceived by in vitro fertilization; no such association was found in the other study. Conclusion: A review of the evidence found an increased risk of adverse perinatal outcome in twins conceived by in vitro fertilization, compared with twin not conceived by in vitro fertilization. However, no statistically significance differences were found after stratification for maternal confounders, with the exception of hospital and NICU admission. The grade for all outcomes was moderate.

Book Pregnancy and Neonatal Outcomes Associated with the Use of Assisted Reproductive Technologies

Download or read book Pregnancy and Neonatal Outcomes Associated with the Use of Assisted Reproductive Technologies written by Andrea Lanes and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Assisted reproductive technologies have become a common method used to treat infertility. These techniques have advanced quickly since the first birth of an in vitro fertilization (IVF) baby in 1978, at the Royal Oldham Hospital in the United Kingdom. Currently, IVF with or without intracytoplasmic sperm injection, is used throughout the world to achieve oocyte retrieval, fertilization, implantation of an embryo, clinical pregnancy, ongoing clinical pregnancy, and a live-born infant. The rationale for selecting one type of fertility treatment over another is multifactorial: the confirmed or unconfirmed cause of infertility, the age of the gamete donor and the recipient, the availability of the type of treatment, and the cost associated with the treatment. The ultimate goal of any fertility treatment is to achieve a successful pregnancy that results in a healthy infant. However, the literature is equivocal on the effects of fertility treatment cycles on the health outcomes of infants and mothers. Presently, there are thirty-six fertility treatment centres across Canada, eighteen of which reside in Ontario. A national, comprehensive database of assisted reproductive technology treatment cycles (Canadian Assisted Reproductive Technologies Register (CARTR) Plus) began collecting data in 2013, and has made the research objectives of this doctoral thesis feasible. Before this data collection system, population-wide studies involving fertility treatments were not possible in Canada. Two understudied issues associated with IVF are the impact of fertility treatments on the maternal serum screening markers used in prenatal screening programs to identify fetal aneuploidies; and the association between fertility treatments and adverse perinatal outcomes, such as preeclampsia and stillbirth. Given the increasing number of women who are using fertility treatments to conceive, it is imperative that studies investigating the association with adverse outcomes are conducted. As the science supporting fertility treatment procedure has advanced, so has prenatal screening. One of the first screening tests that are performed for newly pregnant women, including women who conceived following IVF, is maternal serum screening. The first objective of this doctoral thesis was to systematically review the literature on the association between IVF treatment and maternal serum screening marker levels and nuchal translucency (NT) thickness. After the search and screening of the literature there were 40 studies that were included in this systematic review. A decrease in pregnancy-associated plasma protein A (PAPP-A) and an increase in total human chorionic gonadotropin (hCG) was consistently reported for IVF pregnancies. However, since the levels of the other maternal serum screening markers reported also varied we were unable to generalize about the differences between prenatal screening results in the IVF population. These results led to investigating maternal serum screening marker levels among IVF patients in Ontario, Canada. The second objective of this thesis was three-fold: 1) to investigate the accuracy of IVF identification on the Ontario prenatal screening record, relative to reference standard on the CARTR Plus database; 2) to compare the prenatal screening markers in IVF versus non-IVF pregnancies in the population of Ontario; and 3) to propose updated IVF adjustment factors for prenatal screening in the Ontario population, based on the more accurate coding for IVF status in the CARTR Plus database. Significant differences between IVF and non-IVF groups, based on both the prenatal screening requisition information and CARTR Plus information, were found among the ethnicity adjusted mean multiple of the median (MoM)s for several prenatal screening markers: alpha-fetoprotein (AFP), PAPP-A, unconjugated estriol (μE3), first trimester hCG, total hCG, and dimeric inhibin A (DIA). When we developed the proposed adjustment factors for all CARTR Plus identified pregnancies we found that for PAPP-A, total hCG, and μE3 the mean adjusted marker MoMs were significantly closer to 1.00, as compared to the prenatal screening adjusted or the unadjusted mean marker MoMs. Currently, there is no adjustment made to the other maternal serum screening markers and NT measurement. The third objective was to examine the effect of type of infertility on placental-mediated adverse outcomes (preeclampsia, intrauterine growth restriction, placental abruption, and stillbirth). Type of infertility was classified as male factor (sperm count, poor sperm motility, and abnormal sperm morphology), female factor (ovulation disorders, tubal infertility, and uterine or cervical causes), and unexplained infertility. No significant associations were found between type of conception and the composite outcome, as well as each individual primary outcome. Similarly, the type of infertility was not associated with the composite outcome or any of the individual primary outcomes, except for female factor infertility, which was associated with increased probability of placental abruption. Overall, the results from this doctoral thesis suggest that there are substantial differences seen in maternal serum screening marker MoMs among women who use IVF to conceive, suggesting that appropriate adjustment factors should be employed to ensure accurate results for determining the risk of Down syndrome and trisomy 18. Additionally, although the literature has shown an association between fertility treatment and placental-mediated adverse outcomes no significant associations were found in the population of Ontario. Further studies should be performed to confirm the results of these observational studies.

Book Pregnancy After Assisted Reproductive Technology

Download or read book Pregnancy After Assisted Reproductive Technology written by Eric Jauniaux and published by Cambridge University Press. This book was released on 2012-09-06 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is estimated that more than 4.5 million couples experience infertility each year, and more than 4 million babies have been born using IVF since 1978. However, assisted reproductive technologies continue to raise many medical, social, ethical, political and religious questions, often leading to controversial and sometimes inaccurate opinions about the outcomes of pregnancies resulting from these techniques. This is the first book dedicated to pregnancies arising from assisted reproductive technologies (ART). Chapters cover the most important management issues, from early pregnancy to outcome of children resulting from ART, including gynaecological, genetic and obstetric complications. Each chapter is written and edited by leading experts in the field of human reproduction. A timely, practical and evidence-based guide to the management of ART pregnancies, based on 30 years of clinical experience, this is essential reading for reproductive and maternal-fetal specialists as well as general obstetricians and gynaecologists.

Book Assisted Reproduction Techniques

Download or read book Assisted Reproduction Techniques written by Khaldoun Sharif and published by John Wiley & Sons. This book was released on 2012-03-26 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assisted reproduction techniques have led to the birth of 4 million babies worldwide Assisted reproduction techniques (ART), in particular in-vitro fertilization and intra-cytoplasmic sperm injection, are the most advanced forms of infertility treatment. They involve numerous counseling, medical, surgical and laboratory-based steps. At each step various problems and complications could be encountered that challenge even the most experienced ART practitioners. Moreover, patients with complex medical disorders may require ART, presenting further challenges. Assisted Reproduction Techniques will stimulate resourceful thinking in the ART practitioner when faced with these challenges. It outlines various management options, the reasoning behind them, and the evidence on which they are based to enable the practitioner to choose the most suitable solution for the needs of each patient. Written by 122 internationally renowned experts, Assisted Reproduction Techniques follows the patient's journey throughout the whole ART process, with chapters on: Counseling and preparation Ovarian stimulation Oocyte retrieval Embryo transfer The luteal phase The ART laboratory The male patient The ART pregnancy Each of the 100 concise chapters includes clinical cases, background, evidence-based practical management options, preventive measures and key-point summaries of the important details. Assisted Reproduction Techniques gives a wide-ranging practical guide to all those wishing to support couples who cannot conceive naturally.

Book Clinical Management of Pregnancies following ART

Download or read book Clinical Management of Pregnancies following ART written by Kanna Jayaprakasan and published by Springer. This book was released on 2016-11-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed overview of the possible risks associated with ART pregnancies and their clinical management. While most pregnancies following Assisted Reproduction Treatment (ART) will progress normally and without any complications to mother or baby, some women who conceive after ART as well as their babies are at increased risk of pregnancy complications. There are some schools of thoughts proposing pregnancies following IVF should be regarded as being “high risk” and requires special attention. There are various reasons why ART pregnancies may be at higher risk – Female and male age factor, increased chance of multiple pregnancies, underlying cause of subfertility (pelvic pathology, uterine pathology, endometrial dysfunction) and potential increase in birth defects. This is an essential read for obstetricians, fertility specialists and Post-graduate trainees.​

Book Assisted Reproductive Technology Surveillance

Download or read book Assisted Reproductive Technology Surveillance written by Dmitry M. Kissin and published by Cambridge University Press. This book was released on 2019-07-04 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a comprehensive guide to assisted reproductive technology surveillance, describing its history, global variations, and best practices.

Book Infertility and Impaired Fecundity in the United States  1982 2010

Download or read book Infertility and Impaired Fecundity in the United States 1982 2010 written by Anjani Chandra and published by . This book was released on 2013 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Textbook of Assisted Reproduction

Download or read book Textbook of Assisted Reproduction written by Gautam Nand Allahbadia and published by Springer Nature. This book was released on 2020-08-05 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: Groundbreaking, comprehensive, and developed by a panel of leading international experts in the field, Textbook of Assisted Reproduction provides a multidisciplinary overview of the diagnosis and management of infertility, which affects 15% of all couples around the world. The book aims to cover all aspects of assisted reproduction. Particular attention is given to topics such as the assessment of infertile couples; assisted reproductive techniques (ARTs) including ovulation induction, intra uterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (clinical and laboratory aspects); reproductive genetics; and obstetric and perinatal outcomes.

Book Long Term Safety of Assisted Reproduction

Download or read book Long Term Safety of Assisted Reproduction written by Arianna D'Angelo and published by CRC Press. This book was released on 2022-03-28 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A much-needed overview of the available information now accumulating to indicate that assisted reproductive technologies are generally safe for both babies and mothers. However, the literature abounds with reports of a higher risk of obstetric and perinatal complications; regarding the long term outcomes for both women and children, the data are still scarce. The chapters summarized in this book review the current knowledge on long term safety of assisted reproduction and indicate the need for continued research to cover the lack of data in some specific patient groups and for recently developed treatments that only have a short period of follow-up.

Book Ultrasonography in Reproductive Medicine and Infertility

Download or read book Ultrasonography in Reproductive Medicine and Infertility written by Botros R. M. B. Rizk and published by Cambridge University Press. This book was released on 2010-03-25 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowhere has the impact of ultrasonography been more dramatic than in reproductive medicine, particularly in the diagnosis of female and male infertility, the management of assisted reproductive procedures and the monitoring of early pregnancy. This authoritative textbook encompasses the complete role of ultrasonography in the evaluation of infertility and assisted reproduction. Covering every indication for ultrasonography in assisted reproductive technology, this will prove an invaluable resource in the evaluation of the infertile patient and optimization of the outcome of treatment. The interpretation of images to improve fertility and reproductive success is emphasized throughout. Ultrasonography in Reproductive Medicine and Infertility is essential reading for clinicians working both in IVF clinics and in office practice. It will be particularly useful to gynecologists, infertility specialists, ultrasonographers and radiologists working in reproductive endocrinology and infertility, assisted reproductive technology, ultrasonography and radiology.

Book The 1988 National Maternal and Infant Health Survey  NMIHS

Download or read book The 1988 National Maternal and Infant Health Survey NMIHS written by and published by . This book was released on 1986 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: This publication reports the results of three meetings held to plan the 1988 National Material and Infant Health Survey (NMIHS). The purposes of the meetings were: to layout methodological and policy issues which will affect the 1988 NMIHS; to examine the relationship of the 1988 NMIHS to other National Center for Health Statistics surveys; and to review contracting mechanisms ann funding sources annd alternatives.