Download or read book Archibald Garrod and the Individuality of Man written by Alexander G. Bearn and published by Oxford University Press, USA. This book was released on 1993 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this scholarly and insightful biography, Alexander G. Bearn, a physician and a scientist in the Garrodian tradition, has drawn a portrait of one of the great minds of twentieth century medicine. It is story of intellectual achievement. But the book also gives a fascinating account of the life of a talented professional family and a perspective on the practice of medicine and on medical education at the turn of the century. Archibald Garrod is chiefly remembered as the originator of the concept of inborn metabolic error, an idea which grew from his studies of families with diseases whose biochemical basis he was able to identify. He was widely recognized for this achievement in his own lifetime and held a respected position in the medical establishment, a position accorded to him on the basis of his scientific achievement rather than for any great clinical skill. But to concentrate on the concept of inborn errors is to overlook what has in time turned out to be Garrod's greatest achievement, for it was he who first saw that genetics, biochemistry, and medicine are fundamentally linked. He propounded, to all who would listen, his thesis that disease can only be properly studied in the light of an individual's genetic susceptibility, and that that in turn rests on biochemical individuality. Only by thinking of human diseases as the consequences of genetic and environmental interaction are the advances of today's and tomorrow's medicine possible.
Download or read book Archibald Garrod and the Individuality of Man written by Alexander G Bearn and published by American Philosophical Society Press. This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Students of biology learn that Archibald Garrod (1857-1936) advanced the concept of inborn errors of metabolism through brilliant insights into patients with rare genetic diseases. Garrod's two other prescient concepts are often overlooked: (1) the concept of the chemical uniqueness of the individual, which prefigured the modern appreciation of individual predisposition to disease; & (2) the concept of the physician-scientist, which prefigured the modern revolution in biomedical research. All three concepts are brought into sharp focus in this incisive biography, written devotedly by Alexander G. Bearn, a disciple whose own career is based firmly on the Garrodian tradition. Illustrations.
Download or read book Genetic Medicine written by Barton Childs and published by JHU Press. This book was released on 2003-09-15 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Genetic Medicine: A Logic of Disease, Barton Childs demonstrates that knowledge of the ways both genes and environment contribute to disease provides a rational basis for medical thinking. This "genetic" medicine, he explains, should help the physician use the results of laboratory tests to perceive the uniqueness of the patient as well as that of the family and the cultural conditions in which the patient's condition arose. Childs thus provides a conceptual framework within which to teach and practice a humane medicine.
Download or read book The Science of Human Perfection written by Nathaniel Comfort and published by Yale University Press. This book was released on 2012-09-25 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost daily we hear news stories, advertisements, and scientific reports that promise genetic medicine will make us live longer, enable doctors to identify and treat diseases before they start, and individualize our medical care. But surprisingly, a century ago eugenicists were making the same promises. The Science of Human Perfection traces the history of the promises of medical genetics and of the medical dimension of eugenics. The book also considers social and ethical issues that cast troublesome shadows over these fields./divDIV DIVKeeping his focus on America, science historian Nathaniel Comfort introduces the community of scientists, physicians, and public health workers who have contributed to the development of medical genetics from the nineteenth century to today. He argues that medical genetics is closely related to eugenics, and indeed the two cannot be fully understood separately. He also carefully examines how the desire to relieve suffering and to improve ourselves genetically, though noble, may be subverted. History makes clear that as patients and consumers we must take ownership of genetic medicine, using it intelligently, knowledgeably, and skeptically, lest pernicious interests trump our own./div
Download or read book Genes Chromosomes and Disease written by Nicholas Wright Gillham and published by FT Press. This book was released on 2011-03-15 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University. The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.
Download or read book Genesis written by Jan Sapp and published by Oxford : Oxford University Press. This book was released on 2003 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is evolution? What is a gene? How did these concepts originate and how did they develop? This book is a short history ranging from Lamarck and Darwin to DNA and the Human Genome Project, exploring the conceptual oppositions, techniques, institutional conditions and controversies that have shaped the development of biology.
Download or read book Nature and Society in Historical Context written by Mikulas Teich and published by Cambridge University Press. This book was released on 1997-02-13 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of essays describing the historical connection between nature and society.
Download or read book Color Atlas of Genetics written by Eberhard Passarge and published by Thieme. This book was released on 2011-01-01 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: A remarkable achievement by a single author...concise but informative...No geneticist or physician interested in genetic diseases should be without a copy of this remarkable edition. --American Journal of Medical GeneticsMore than ever, a solid understanding of genetics is a fundamental element of all medical and scientific educational programs, across virtually all disciplines. And the applications--and implications--of genetic research are at the heart of current medical scientific debates. Completely updated and revised, The Color Atlas of Genetics is an invaluable guide for students of medicine and biology, clinicians, and anyone else interested in this rapidly evolving field. The latest edition of this highly praised atlas retains several popular features, such as the accessible layout and logical structure, in addition to many novel features and 20 completely new color plates on new topics, including: Cell-to-cell communication, including important signaling and metabolic pathways Taxonomy of living organisms (tree of life) Epigenetic modifications in chromatin Apoptosis RNA interference (RNAi) Comparative genomic hybridization Origins of cancer Principles of gene and stem cell therapy, etc. With more than 200 absorbing full-color plates concisely explained on facing pages, the atlas offers readers an easy-to-use, yet remarkably detailed guide to key molecular, theoretical, and medical aspects of genetics and genomics. Brief descriptions of numerous genetic diseases are included, with references for more detailed information.Readers will find that this incomparable book presents a comprehensive picture of the field from its fascinating history to its most advanced applications.
Download or read book Heredity and Hope written by Ruth Schwartz COWAN and published by Harvard University Press. This book was released on 2009-06-30 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neither minimizing the difficulty of the choices that modern genetics has created for us nor fearing them, Cowan argues that we can improve the quality of our own lives and the lives of our children by using the modern science and technology of genetic screening responsibly.
Download or read book Gout written by Roy Porter and published by Yale University Press. This book was released on 2000-01-01 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gout has been seen as a disease afflicting upper-class males of superior wit, genius and creativity. It is also believed to protect its sufferers and assure long life. This study investigates the history of gout and offers a perspective on medical and social history, sex, prejudice and class.
Download or read book Sir Clifford Allbutt written by Alexander G. Bearn and published by Royal College of Physicians. This book was released on 2007 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monograph looking at the life of Sir Clifford Allbutt, inventor of the short themometer and responsible for introducing the opthalmoscope, weighing machine and microscope to the wards.
Download or read book The 100 Most Influential Medical Pioneers of All Time written by Monica Gill and published by Encyclopaedia Britannica. This book was released on 2016-07-15 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents biographies of 100 individuals in the medical field responsible for everything from vaccinations to gene therapy. It allows readers to understand how each pioneer built on the work of his or her peers and predecessors and how concepts relate to each other.
Download or read book Perspectives on Genetics written by James Franklin Crow and published by Univ of Wisconsin Press. This book was released on 2000 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than ten years, the distinguished geneticists James F. Crow and William F. Dove have edited the popular "Perspectives" column in Genetics, the journal of the Genetics Society of America. This book, Perspectives on Genetics, collects more than 100 of these essays, which cumulatively are a history of modern genetics research and its continuing evolution.
Download or read book Making Faces written by Adam S. Wilkins and published by Harvard University Press. This book was released on 2017-01-02 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans possess the most expressive faces in the animal kingdom. Adam Wilkins presents evidence ranging from the fossil record to recent findings of genetics, molecular biology, and developmental biology to reconstruct the fascinating story of how the human face evolved. Beginning with the first vertebrate faces half a billion years ago and continuing to dramatic changes among our recent human ancestors, Making Faces illuminates how the unusual characteristics of the human face came about—both the physical shape of facial features and the critical role facial expression plays in human society. Offering more than an account of morphological changes over time and space, which rely on findings from paleontology and anthropology, Wilkins also draws on comparative studies of living nonhuman species. He examines the genetic foundations of the remarkable diversity in human faces, and also shows how the evolution of the face was intimately connected to the evolution of the brain. Brain structures capable of recognizing different individuals as well as “reading” and reacting to their facial expressions led to complex social exchanges. Furthermore, the neural and muscular mechanisms that created facial expressions also allowed the development of speech, which is unique to humans. In demonstrating how the physical evolution of the human face has been inextricably intertwined with our species’ growing social complexity, Wilkins argues that it was both the product and enabler of human sociality.
Download or read book Genetics Manual Current Theory Concepts Terms written by George P Redei and published by World Scientific. This book was released on 1998-03-31 with total page 1153 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1,150 pages contain more information than any other comparable book. It is not a glossary or dictionary or review because all concepts are explained, not just defined or mentioned.Covers the latest developments, usually missed in textbooks and monographs.The broad range of modern genetics, of cell and molecular biology, biometry, etc. are included without glossing over the classical foundations.The hundreds of simple and clear illustrations are vey useful for classroom purposes because they can be drawn on the blackboard or projected on a screen without taking much time to make the crucial points.The cross-references among the entries tie the contents into an extremely useful comprehensive textbook.The concise style leads the reader to the point without verbiage.The etymology of the terms is explained.The text is not intimidating and it is very easy to read because all the terms are explained within the book. Most of the biometrical procedures are presented by worked-out examples in a plain form, rarely or not found at all in other books.It effectively reaches out to non-geneticists without compromising high scientific standards. Usually the most essential features of a concept are presented at the beginning of the entry, and the reader can go as far as she/he feels needed about the logic.The WEB and e-mail addresses of databases and other sources of detailed information are very helpful.A well selected list of about 1000 references, published mainly in the last couple of years, completes the volume.The moderate price makes it a best buy, and an excellent choice to own for students, teachers, scientists, physicians, lawyers and all educated persons who cannot afford an entire library yet wish to be well informed.
Download or read book Tay Sachs Disease written by and published by Elsevier. This book was released on 2001-10-10 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tay-Sachs disease is a rare hereditary disease caused by a genetic mutation that leaves the body unable to produce an enzyme necessary for fat metabolism in nerve cells, producing central nervous system degeneration. In infants, it is characterized by progressive mental deterioration, blindness, paralysis, epileptic seizures, and death by age four. Adult-onset Tay-Sachs occurs in persons who have a genetic mutation that is similar but allows some production of the missing enzyme. There is no treatment for Tay-Sachs.A test to determine whether an infant is carrying the Tay-Sachs disease was introduced in 1969. However, work continues to be done to help find a cure. Because there is no cure for this deadly disease, genetic research is essential. Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field.
Download or read book Concussion and Traumatic Encephalopathy written by Jeff Victoroff and published by Cambridge University Press. This book was released on 2019-02-28 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Readers will discover how very recent scientific advances have overthrown a century of dogma about concussive brain injury.
