Download or read book Application of Graph Based Data Mining to Biological Networks written by Chang hun You and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A huge amount of biological data has been generated by long-term research. It is time to start to focus on a system-level understanding of bio-systems. Biological networks are networks of biochemical reactions, containing various objects and their relationships. Understanding of biological networks is a starting point of systems biology. Multi-relational data mining finds the relational patterns in both the entity attributes and relations in the data. A widely used representation for relational data is a graph consisting of vertices and edges between these vertices. Graph-based data mining, as one approach of multi-relational data mining, finds relational patterns in a graph representation of data. This thesis will present a graph representation of biological networks including almost all features of pathways, and apply the Subdue graph-based data mining system in both supervised and unsupervised settings. This research will also show that the patterns found by Subdue have important biological meaning.
Download or read book Networks in Cell Biology written by Mark Buchanan and published by Cambridge University Press. This book was released on 2010-05-13 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key introductory text for graduate students and researchers in physics, biology and biochemistry.
Download or read book Mining Graph Data written by Diane J. Cook and published by John Wiley & Sons. This book was released on 2006-12-18 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text takes a focused and comprehensive look at mining data represented as a graph, with the latest findings and applications in both theory and practice provided. Even if you have minimal background in analyzing graph data, with this book you’ll be able to represent data as graphs, extract patterns and concepts from the data, and apply the methodologies presented in the text to real datasets. There is a misprint with the link to the accompanying Web page for this book. For those readers who would like to experiment with the techniques found in this book or test their own ideas on graph data, the Web page for the book should be http://www.eecs.wsu.edu/MGD.
Download or read book Learning Patterns in Dynamic Graphs with Application to Biological Networks written by Chang Hun You and published by . This book was released on 2009 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Managing and Mining Graph Data written by Charu C. Aggarwal and published by Springer Science & Business Media. This book was released on 2010-02-02 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing and Mining Graph Data is a comprehensive survey book in graph management and mining. It contains extensive surveys on a variety of important graph topics such as graph languages, indexing, clustering, data generation, pattern mining, classification, keyword search, pattern matching, and privacy. It also studies a number of domain-specific scenarios such as stream mining, web graphs, social networks, chemical and biological data. The chapters are written by well known researchers in the field, and provide a broad perspective of the area. This is the first comprehensive survey book in the emerging topic of graph data processing. Managing and Mining Graph Data is designed for a varied audience composed of professors, researchers and practitioners in industry. This volume is also suitable as a reference book for advanced-level database students in computer science and engineering.
Download or read book Biological Data Mining And Its Applications In Healthcare written by Xiaoli Li and published by World Scientific. This book was released on 2013-11-28 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologists are stepping up their efforts in understanding the biological processes that underlie disease pathways in the clinical contexts. This has resulted in a flood of biological and clinical data from genomic and protein sequences, DNA microarrays, protein interactions, biomedical images, to disease pathways and electronic health records. To exploit these data for discovering new knowledge that can be translated into clinical applications, there are fundamental data analysis difficulties that have to be overcome. Practical issues such as handling noisy and incomplete data, processing compute-intensive tasks, and integrating various data sources, are new challenges faced by biologists in the post-genome era. This book will cover the fundamentals of state-of-the-art data mining techniques which have been designed to handle such challenging data analysis problems, and demonstrate with real applications how biologists and clinical scientists can employ data mining to enable them to make meaningful observations and discoveries from a wide array of heterogeneous data from molecular biology to pharmaceutical and clinical domains.
Download or read book Biological Network Analysis written by Pietro Hiram Guzzi and published by Elsevier. This book was released on 2020-05-11 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Network Analysis: Trends, Approaches, Graph Theory, and Algorithms considers three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN), and Human Brain Connectomes. The book's authors discuss various graph theoretic and data analytics approaches used to analyze these networks with respect to available tools, technologies, standards, algorithms and databases for generating, representing and analyzing graphical data. As a wide variety of algorithms have been developed to analyze and compare networks, this book is a timely resource. Presents recent advances in biological network analysis, combining Graph Theory, Graph Analysis, and various network models Discusses three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN) and Human Brain Connectomes Includes a discussion of various graph theoretic and data analytics approaches
Download or read book Graph Data Mining written by Qi Xuan and published by Springer Nature. This book was released on 2021-07-15 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Graph data is powerful, thanks to its ability to model arbitrary relationship between objects and is encountered in a range of real-world applications in fields such as bioinformatics, traffic network, scientific collaboration, world wide web and social networks. Graph data mining is used to discover useful information and knowledge from graph data. The complications of nodes, links and the semi-structure form present challenges in terms of the computation tasks, e.g., node classification, link prediction, and graph classification. In this context, various advanced techniques, including graph embedding and graph neural networks, have recently been proposed to improve the performance of graph data mining. This book provides a state-of-the-art review of graph data mining methods. It addresses a current hot topic – the security of graph data mining – and proposes a series of detection methods to identify adversarial samples in graph data. In addition, it introduces readers to graph augmentation and subgraph networks to further enhance the models, i.e., improve their accuracy and robustness. Lastly, the book describes the applications of these advanced techniques in various scenarios, such as traffic networks, social and technical networks, and blockchains.
Download or read book Statistical and Machine Learning Approaches for Network Analysis written by Matthias Dehmer and published by John Wiley & Sons. This book was released on 2012-06-26 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the multidisciplinary nature of complex networks through machine learning techniques Statistical and Machine Learning Approaches for Network Analysis provides an accessible framework for structurally analyzing graphs by bringing together known and novel approaches on graph classes and graph measures for classification. By providing different approaches based on experimental data, the book uniquely sets itself apart from the current literature by exploring the application of machine learning techniques to various types of complex networks. Comprised of chapters written by internationally renowned researchers in the field of interdisciplinary network theory, the book presents current and classical methods to analyze networks statistically. Methods from machine learning, data mining, and information theory are strongly emphasized throughout. Real data sets are used to showcase the discussed methods and topics, which include: A survey of computational approaches to reconstruct and partition biological networks An introduction to complex networks—measures, statistical properties, and models Modeling for evolving biological networks The structure of an evolving random bipartite graph Density-based enumeration in structured data Hyponym extraction employing a weighted graph kernel Statistical and Machine Learning Approaches for Network Analysis is an excellent supplemental text for graduate-level, cross-disciplinary courses in applied discrete mathematics, bioinformatics, pattern recognition, and computer science. The book is also a valuable reference for researchers and practitioners in the fields of applied discrete mathematics, machine learning, data mining, and biostatistics.
Download or read book Graph Based Mining on Weighted Directed Graphs for Subnetworks and Path Discovery written by Sijin Cherupilly Abdulkarim and published by . This book was released on 2011 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Subnetwork or path mining is an emerging data mining problem in many areas including scientific and commercial applications. Graph modeling is one of the effective ways in representing real world networks. Many natural and man-made systems are structured in the form of networks. Traditional machine learning and data mining approaches assume data as a collection of homogenous objects that are independent of each other whereas network data are potentially heterogeneous and interlinked. In this paper we propose a novel algorithm to find subnetworks and Maximal paths from a weighted, directed network represented as a graph. The main objective of this study is to find meaningful Maximal paths from a given network based on three key parameters: node weight, edge weight, and direction. This algorithm is an effective way to extract Maximal paths from a network modeled based on a user's interest. Also, the proposed algorithm allows the user to incorporate weights to the nodes and edges of a biological network. The performance of the proposed technique was tested using a Colorectal Cancer biological network. The subnetworks and paths obtained through our network mining algorithm from the biological network were scored based on their biological significance. The subnetworks and Maximal paths derived were verified using MetacoreTM as well as literature. The algorithm is developed into a tool where the user can input the node list and the edge list. The tool can also find out the upstream and downstream of a given entity (genes/proteins etc.) from the derived Maximal paths. The complexity of finding the algorithm is found to be O(nlogn) in the best case and O(n^2 logn) in the worst case.
Download or read book Graph Mining written by Deepayan Chakrabarti and published by Morgan & Claypool Publishers. This book was released on 2012-10-01 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does the Web look like? How can we find patterns, communities, outliers, in a social network? Which are the most central nodes in a network? These are the questions that motivate this work. Networks and graphs appear in many diverse settings, for example in social networks, computer-communication networks (intrusion detection, traffic management), protein-protein interaction networks in biology, document-text bipartite graphs in text retrieval, person-account graphs in financial fraud detection, and others. In this work, first we list several surprising patterns that real graphs tend to follow. Then we give a detailed list of generators that try to mirror these patterns. Generators are important, because they can help with "what if" scenarios, extrapolations, and anonymization. Then we provide a list of powerful tools for graph analysis, and specifically spectral methods (Singular Value Decomposition (SVD)), tensors, and case studies like the famous "pageRank" algorithm and the "HITS" algorithm for ranking web search results. Finally, we conclude with a survey of tools and observations from related fields like sociology, which provide complementary viewpoints. Table of Contents: Introduction / Patterns in Static Graphs / Patterns in Evolving Graphs / Patterns in Weighted Graphs / Discussion: The Structure of Specific Graphs / Discussion: Power Laws and Deviations / Summary of Patterns / Graph Generators / Preferential Attachment and Variants / Incorporating Geographical Information / The RMat / Graph Generation by Kronecker Multiplication / Summary and Practitioner's Guide / SVD, Random Walks, and Tensors / Tensors / Community Detection / Influence/Virus Propagation and Immunization / Case Studies / Social Networks / Other Related Work / Conclusions
Download or read book Analysis and Enumeration written by Andrea Marino and published by Springer. This book was released on 2015-03-23 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work we plan to revise the main techniques for enumeration algorithms and to show four examples of enumeration algorithms that can be applied to efficiently deal with some biological problems modelled by using biological networks: enumerating central and peripheral nodes of a network, enumerating stories, enumerating paths or cycles, and enumerating bubbles. Notice that the corresponding computational problems we define are of more general interest and our results hold in the case of arbitrary graphs. Enumerating all the most and less central vertices in a network according to their eccentricity is an example of an enumeration problem whose solutions are polynomial and can be listed in polynomial time, very often in linear or almost linear time in practice. Enumerating stories, i.e. all maximal directed acyclic subgraphs of a graph G whose sources and targets belong to a predefined subset of the vertices, is on the other hand an example of an enumeration problem with an exponential number of solutions, that can be solved by using a non trivial brute-force approach. Given a metabolic network, each individual story should explain how some interesting metabolites are derived from some others through a chain of reactions, by keeping all alternative pathways between sources and targets. Enumerating cycles or paths in an undirected graph, such as a protein-protein interaction undirected network, is an example of an enumeration problem in which all the solutions can be listed through an optimal algorithm, i.e. the time required to list all the solutions is dominated by the time to read the graph plus the time required to print all of them. By extending this result to directed graphs, it would be possible to deal more efficiently with feedback loops and signed paths analysis in signed or interaction directed graphs, such as gene regulatory networks. Finally, enumerating mouths or bubbles with a source s in a directed graph, that is enumerating all the two vertex-disjoint directed paths between the source s and all the possible targets, is an example of an enumeration problem in which all the solutions can be listed through a linear delay algorithm, meaning that the delay between any two consecutive solutions is linear, by turning the problem into a constrained cycle enumeration problem. Such patterns, in a de Bruijn graph representation of the reads obtained by sequencing, are related to polymorphisms in DNA- or RNA-seq data.
Download or read book Data Mining for Bioinformatics written by Sumeet Dua and published by CRC Press. This book was released on 2012-11-06 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering theory, algorithms, and methodologies, as well as data mining technologies, Data Mining for Bioinformatics provides a comprehensive discussion of data-intensive computations used in data mining with applications in bioinformatics. It supplies a broad, yet in-depth, overview of the application domains of data mining for bioinformatics to he
Download or read book Link Mining Models Algorithms and Applications written by Philip S. Yu and published by Springer Science & Business Media. This book was released on 2010-09-16 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers detailed surveys and systematic discussion of models, algorithms and applications for link mining, focusing on theory and technique, and related applications: text mining, social network analysis, collaborative filtering and bioinformatics.
Download or read book Biological Data Mining written by Jake Y. Chen and published by CRC Press. This book was released on 2009-09-01 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like a data-guzzling turbo engine, advanced data mining has been powering post-genome biological studies for two decades. Reflecting this growth, Biological Data Mining presents comprehensive data mining concepts, theories, and applications in current biological and medical research. Each chapter is written by a distinguished team of interdisciplin
Download or read book Graph Representation Learning written by William L. William L. Hamilton and published by Springer Nature. This book was released on 2022-06-01 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Graph-structured data is ubiquitous throughout the natural and social sciences, from telecommunication networks to quantum chemistry. Building relational inductive biases into deep learning architectures is crucial for creating systems that can learn, reason, and generalize from this kind of data. Recent years have seen a surge in research on graph representation learning, including techniques for deep graph embeddings, generalizations of convolutional neural networks to graph-structured data, and neural message-passing approaches inspired by belief propagation. These advances in graph representation learning have led to new state-of-the-art results in numerous domains, including chemical synthesis, 3D vision, recommender systems, question answering, and social network analysis. This book provides a synthesis and overview of graph representation learning. It begins with a discussion of the goals of graph representation learning as well as key methodological foundations in graph theory and network analysis. Following this, the book introduces and reviews methods for learning node embeddings, including random-walk-based methods and applications to knowledge graphs. It then provides a technical synthesis and introduction to the highly successful graph neural network (GNN) formalism, which has become a dominant and fast-growing paradigm for deep learning with graph data. The book concludes with a synthesis of recent advancements in deep generative models for graphs—a nascent but quickly growing subset of graph representation learning.
Download or read book Biomedical Data and Applications written by Amandeep S. Sidhu and published by Springer Science & Business Media. This book was released on 2009-06-16 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compared with data from general application domains, modern biological data has many unique characteristics. The goal of this book is to cover data and applications identifying new issues and directions for future research in biomedical domain.
