Download or read book Bayesian Inference for Gene Expression and Proteomics written by Kim-Anh Do and published by Cambridge University Press. This book was released on 2006-07-24 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert overviews of Bayesian methodology, tools and software for multi-platform high-throughput experimentation.

Download or read book Practical Guide to Cluster Analysis in R written by Alboukadel Kassambara and published by STHDA. This book was released on 2017-08-23 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although there are several good books on unsupervised machine learning, we felt that many of them are too theoretical. This book provides practical guide to cluster analysis, elegant visualization and interpretation. It contains 5 parts. Part I provides a quick introduction to R and presents required R packages, as well as, data formats and dissimilarity measures for cluster analysis and visualization. Part II covers partitioning clustering methods, which subdivide the data sets into a set of k groups, where k is the number of groups pre-specified by the analyst. Partitioning clustering approaches include: K-means, K-Medoids (PAM) and CLARA algorithms. In Part III, we consider hierarchical clustering method, which is an alternative approach to partitioning clustering. The result of hierarchical clustering is a tree-based representation of the objects called dendrogram. In this part, we describe how to compute, visualize, interpret and compare dendrograms. Part IV describes clustering validation and evaluation strategies, which consists of measuring the goodness of clustering results. Among the chapters covered here, there are: Assessing clustering tendency, Determining the optimal number of clusters, Cluster validation statistics, Choosing the best clustering algorithms and Computing p-value for hierarchical clustering. Part V presents advanced clustering methods, including: Hierarchical k-means clustering, Fuzzy clustering, Model-based clustering and Density-based clustering.

Download or read book Bayesian Data Analysis Third Edition written by Andrew Gelman and published by CRC Press. This book was released on 2013-11-01 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, this classic book is widely considered the leading text on Bayesian methods, lauded for its accessible, practical approach to analyzing data and solving research problems. Bayesian Data Analysis, Third Edition continues to take an applied approach to analysis using up-to-date Bayesian methods. The authors—all leaders in the statistics community—introduce basic concepts from a data-analytic perspective before presenting advanced methods. Throughout the text, numerous worked examples drawn from real applications and research emphasize the use of Bayesian inference in practice. New to the Third Edition Four new chapters on nonparametric modeling Coverage of weakly informative priors and boundary-avoiding priors Updated discussion of cross-validation and predictive information criteria Improved convergence monitoring and effective sample size calculations for iterative simulation Presentations of Hamiltonian Monte Carlo, variational Bayes, and expectation propagation New and revised software code The book can be used in three different ways. For undergraduate students, it introduces Bayesian inference starting from first principles. For graduate students, the text presents effective current approaches to Bayesian modeling and computation in statistics and related fields. For researchers, it provides an assortment of Bayesian methods in applied statistics. Additional materials, including data sets used in the examples, solutions to selected exercises, and software instructions, are available on the book’s web page.

Download or read book Integrating Omics Data written by George Tseng and published by Cambridge University Press. This book was released on 2015-09-23 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tutorial chapters by leaders in the field introduce state-of-the-art methods to handle information integration problems of omics data.

Download or read book Doing Bayesian Data Analysis written by John Kruschke and published by Academic Press. This book was released on 2014-11-11 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doing Bayesian Data Analysis: A Tutorial with R, JAGS, and Stan, Second Edition provides an accessible approach for conducting Bayesian data analysis, as material is explained clearly with concrete examples. Included are step-by-step instructions on how to carry out Bayesian data analyses in the popular and free software R and WinBugs, as well as new programs in JAGS and Stan. The new programs are designed to be much easier to use than the scripts in the first edition. In particular, there are now compact high-level scripts that make it easy to run the programs on your own data sets. The book is divided into three parts and begins with the basics: models, probability, Bayes' rule, and the R programming language. The discussion then moves to the fundamentals applied to inferring a binomial probability, before concluding with chapters on the generalized linear model. Topics include metric-predicted variable on one or two groups; metric-predicted variable with one metric predictor; metric-predicted variable with multiple metric predictors; metric-predicted variable with one nominal predictor; and metric-predicted variable with multiple nominal predictors. The exercises found in the text have explicit purposes and guidelines for accomplishment. This book is intended for first-year graduate students or advanced undergraduates in statistics, data analysis, psychology, cognitive science, social sciences, clinical sciences, and consumer sciences in business. - Accessible, including the basics of essential concepts of probability and random sampling - Examples with R programming language and JAGS software - Comprehensive coverage of all scenarios addressed by non-Bayesian textbooks: t-tests, analysis of variance (ANOVA) and comparisons in ANOVA, multiple regression, and chi-square (contingency table analysis) - Coverage of experiment planning - R and JAGS computer programming code on website - Exercises have explicit purposes and guidelines for accomplishment - Provides step-by-step instructions on how to conduct Bayesian data analyses in the popular and free software R and WinBugs

Download or read book Statistical Analysis of Gene Expression Microarray Data written by Terry Speed and published by CRC Press. This book was released on 2003-03-26 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although less than a decade old, the field of microarray data analysis is now thriving and growing at a remarkable pace. Biologists, geneticists, and computer scientists as well as statisticians all need an accessible, systematic treatment of the techniques used for analyzing the vast amounts of data generated by large-scale gene expression studies

Download or read book Joint Species Distribution Modelling written by Otso Ovaskainen and published by Cambridge University Press. This book was released on 2020-06-11 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive account of joint species distribution modelling, covering statistical analyses in light of modern community ecology theory.

Download or read book Bayesian Statistics A Review written by D. V. Lindley and published by SIAM. This book was released on 1972-01-31 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: A study of those statistical ideas that use a probability distribution over parameter space. The first part describes the axiomatic basis in the concept of coherence and the implications of this for sampling theory statistics. The second part discusses the use of Bayesian ideas in many branches of statistics.

Download or read book Likelihood Bayesian and MCMC Methods in Quantitative Genetics written by Daniel Sorensen and published by Springer Science & Business Media. This book was released on 2007-03-22 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, suitable for numerate biologists and for applied statisticians, provides the foundations of likelihood, Bayesian and MCMC methods in the context of genetic analysis of quantitative traits. Although a number of excellent texts in these areas have become available in recent years, the basic ideas and tools are typically described in a technically demanding style and contain much more detail than necessary. Here, an effort has been made to relate biological to statistical parameters throughout, and the book includes extensive examples that illustrate the developing argument.

Download or read book The BUGS Book written by David Lunn and published by CRC Press. This book was released on 2012-10-02 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian statistical methods have become widely used for data analysis and modelling in recent years, and the BUGS software has become the most popular software for Bayesian analysis worldwide. Authored by the team that originally developed this software, The BUGS Book provides a practical introduction to this program and its use. The text presents

Download or read book Bayesian Hierarchical Models written by Peter D. Congdon and published by CRC Press. This book was released on 2019-09-16 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: An intermediate-level treatment of Bayesian hierarchical models and their applications, this book demonstrates the advantages of a Bayesian approach to data sets involving inferences for collections of related units or variables, and in methods where parameters can be treated as random collections. Through illustrative data analysis and attention to statistical computing, this book facilitates practical implementation of Bayesian hierarchical methods. The new edition is a revision of the book Applied Bayesian Hierarchical Methods. It maintains a focus on applied modelling and data analysis, but now using entirely R-based Bayesian computing options. It has been updated with a new chapter on regression for causal effects, and one on computing options and strategies. This latter chapter is particularly important, due to recent advances in Bayesian computing and estimation, including the development of rjags and rstan. It also features updates throughout with new examples. The examples exploit and illustrate the broader advantages of the R computing environment, while allowing readers to explore alternative likelihood assumptions, regression structures, and assumptions on prior densities. Features: Provides a comprehensive and accessible overview of applied Bayesian hierarchical modelling Includes many real data examples to illustrate different modelling topics R code (based on rjags, jagsUI, R2OpenBUGS, and rstan) is integrated into the book, emphasizing implementation Software options and coding principles are introduced in new chapter on computing Programs and data sets available on the book’s website

Download or read book Bayesian Data Analysis in Ecology Using Linear Models with R BUGS and Stan written by Franzi Korner-Nievergelt and published by Academic Press. This book was released on 2015-04-04 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Data Analysis in Ecology Using Linear Models with R, BUGS, and STAN examines the Bayesian and frequentist methods of conducting data analyses. The book provides the theoretical background in an easy-to-understand approach, encouraging readers to examine the processes that generated their data. Including discussions of model selection, model checking, and multi-model inference, the book also uses effect plots that allow a natural interpretation of data. Bayesian Data Analysis in Ecology Using Linear Models with R, BUGS, and STAN introduces Bayesian software, using R for the simple modes, and flexible Bayesian software (BUGS and Stan) for the more complicated ones. Guiding the ready from easy toward more complex (real) data analyses ina step-by-step manner, the book presents problems and solutions—including all R codes—that are most often applicable to other data and questions, making it an invaluable resource for analyzing a variety of data types. - Introduces Bayesian data analysis, allowing users to obtain uncertainty measurements easily for any derived parameter of interest - Written in a step-by-step approach that allows for eased understanding by non-statisticians - Includes a companion website containing R-code to help users conduct Bayesian data analyses on their own data - All example data as well as additional functions are provided in the R-package blmeco

Download or read book Markov Chain Monte Carlo in Practice written by W.R. Gilks and published by CRC Press. This book was released on 1995-12-01 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a family study of breast cancer, epidemiologists in Southern California increase the power for detecting a gene-environment interaction. In Gambia, a study helps a vaccination program reduce the incidence of Hepatitis B carriage. Archaeologists in Austria place a Bronze Age site in its true temporal location on the calendar scale. And in France,

Download or read book Bayesian Evolutionary Analysis with BEAST written by Alexei J. Drummond and published by Cambridge University Press. This book was released on 2015-08-06 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are the models used in phylogenetic analysis and what exactly is involved in Bayesian evolutionary analysis using Markov chain Monte Carlo (MCMC) methods? How can you choose and apply these models, which parameterisations and priors make sense, and how can you diagnose Bayesian MCMC when things go wrong? These are just a few of the questions answered in this comprehensive overview of Bayesian approaches to phylogenetics. This practical guide: • Addresses the theoretical aspects of the field • Advises on how to prepare and perform phylogenetic analysis • Helps with interpreting analyses and visualisation of phylogenies • Describes the software architecture • Helps developing BEAST 2.2 extensions to allow these models to be extended further. With an accompanying website providing example files and tutorials (http://beast2.org/), this one-stop reference to applying the latest phylogenetic models in BEAST 2 will provide essential guidance for all users – from those using phylogenetic tools, to computational biologists and Bayesian statisticians.

Download or read book Statistical Parametric Mapping The Analysis of Functional Brain Images written by William D. Penny and published by Elsevier. This book was released on 2011-04-28 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an age where the amount of data collected from brain imaging is increasing constantly, it is of critical importance to analyse those data within an accepted framework to ensure proper integration and comparison of the information collected. This book describes the ideas and procedures that underlie the analysis of signals produced by the brain. The aim is to understand how the brain works, in terms of its functional architecture and dynamics. This book provides the background and methodology for the analysis of all types of brain imaging data, from functional magnetic resonance imaging to magnetoencephalography. Critically, Statistical Parametric Mapping provides a widely accepted conceptual framework which allows treatment of all these different modalities. This rests on an understanding of the brain's functional anatomy and the way that measured signals are caused experimentally. The book takes the reader from the basic concepts underlying the analysis of neuroimaging data to cutting edge approaches that would be difficult to find in any other source. Critically, the material is presented in an incremental way so that the reader can understand the precedents for each new development. This book will be particularly useful to neuroscientists engaged in any form of brain mapping; who have to contend with the real-world problems of data analysis and understanding the techniques they are using. It is primarily a scientific treatment and a didactic introduction to the analysis of brain imaging data. It can be used as both a textbook for students and scientists starting to use the techniques, as well as a reference for practicing neuroscientists. The book also serves as a companion to the software packages that have been developed for brain imaging data analysis. - An essential reference and companion for users of the SPM software - Provides a complete description of the concepts and procedures entailed by the analysis of brain images - Offers full didactic treatment of the basic mathematics behind the analysis of brain imaging data - Stands as a compendium of all the advances in neuroimaging data analysis over the past decade - Adopts an easy to understand and incremental approach that takes the reader from basic statistics to state of the art approaches such as Variational Bayes - Structured treatment of data analysis issues that links different modalities and models - Includes a series of appendices and tutorial-style chapters that makes even the most sophisticated approaches accessible

Download or read book Handbook of Behavior Genetics written by Yong-Kyu Kim and published by Springer Science & Business Media. This book was released on 2009-03-25 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.

Download or read book Graphical Models Exponential Families and Variational Inference written by Martin J. Wainwright and published by Now Publishers Inc. This book was released on 2008 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The core of this paper is a general set of variational principles for the problems of computing marginal probabilities and modes, applicable to multivariate statistical models in the exponential family.