Download or read book Textbook of Drug Design and Discovery Third Edition written by Tommy Liljefors and published by CRC Press. This book was released on 2002-07-25 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.
Download or read book Obtaining Discovery Abroad written by and published by American Bar Association. This book was released on 2005 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This newly-revised and expanded edition of Obtaining Discovery Abroad assists those involved in U.S. litigation in understanding the legal and practical steps for bringing evidence from a foreign jurisdiction back to the United States.
Download or read book Drugs written by Rick Ng and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs." —Doody's Reviews, May 2009 "The second edition of a book that offers a user-friendly step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of preclinical trials." —Chemistry World, February 2009 The new edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products. Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs. This second edition features many key enhancements, including Key Points, Chapter Summary, and Review Questions in each chapter, Answers to Review Questions provided in a book-end appendix, and one or two carefully selected "mini" case studies in each chapter. Richly illustrated throughout with over ninety figures and tables, this important book also includes helpful listings of current FDA and European guidelines and a special section on regulatory authority and processes in China. It is an indispensable resource for pharmaceutical industry and academic researchers, pharmaceutical managers and executives, healthcare clinicians, policymakers, regulators, and lobbyists with an interest in drug development. It is also an excellent textbook for students in pharmacy, science, and medicine courses.
Download or read book Privacy Aware Knowledge Discovery written by Francesco Bonchi and published by CRC Press. This book was released on 2010-12-02 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering research at the frontier of this field, Privacy-Aware Knowledge Discovery: Novel Applications and New Techniques presents state-of-the-art privacy-preserving data mining techniques for application domains, such as medicine and social networks, that face the increasing heterogeneity and complexity of new forms of data. Renowned authorities
Download or read book Industrial Applications of Machine Learning written by Pedro Larrañaga and published by CRC Press. This book was released on 2018-12-12 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Industrial Applications of Machine Learning shows how machine learning can be applied to address real-world problems in the fourth industrial revolution, and provides the required knowledge and tools to empower readers to build their own solutions based on theory and practice. The book introduces the fourth industrial revolution and its current impact on organizations and society. It explores machine learning fundamentals, and includes four case studies that address a real-world problem in the manufacturing or logistics domains, and approaches machine learning solutions from an application-oriented point of view. The book should be of special interest to researchers interested in real-world industrial problems. Features Describes the opportunities, challenges, issues, and trends offered by the fourth industrial revolution Provides a user-friendly introduction to machine learning with examples of cutting-edge applications in different industrial sectors Includes four case studies addressing real-world industrial problems solved with machine learning techniques A dedicated website for the book contains the datasets of the case studies for the reader's reproduction, enabling the groundwork for future problem-solving Uses of three of the most widespread software and programming languages within the engineering and data science communities, namely R, Python, and Weka
Download or read book The Sedona Principles written by Jonathan M. Redgrave and published by Pike & Fischer - A BNA Company. This book was released on 2007 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Joint Ventures written by and published by American Bar Association. This book was released on 2006 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Joint Ventures: Antitrust Analysis of Collaborations Among Competitors is the first book to provide a comprehensive analysis of antitrust joint venture law in the immediate aftermath of the Supreme Court's landmark Dagher decision. It reviews antitrust principles applicable to joint ventures and other competitor collaborations, taking into account relevant statutory and case law as well as government guidelines and enforcement practices.
Download or read book Drug Discovery and Development Third Edition written by Taylor & Francis Group and published by CRC Press. This book was released on 2021-06-30 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided. Features: Highlights emerging scientific fields relevant to drug discovery such as the microbiome, nanotechnology, and cancer immunotherapy; and novel research tools such as CRISPR and DNA-encoded libraries Case study detailing the discovery of the anti-cancer drug, lorlatinib Venture capitalist commentary on trends and best practices in drug discovery and development Comprehensive review of regulations and their impact on drug development, highlighting special populations, orphan drugs, and pharmaceutical compounding Multidiscipline functioning of an Academic Research Enterprise, plus a chapter on Ethical Concerns in Research Contributions by 70+ experts from industry and academia specialists who developed and are practitioners of the science and business
Download or read book Molecular Imaging Basic Principles And Applications In Biomedical Research 3rd Edition written by Markus Rudin and published by World Scientific. This book was released on 2020-04-04 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied.The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added.
Download or read book Encyclopedia of Information Science and Technology Third Edition written by Khosrow-Pour, Mehdi and published by IGI Global. This book was released on 2014-07-31 with total page 7972 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This 10-volume compilation of authoritative, research-based articles contributed by thousands of researchers and experts from all over the world emphasized modern issues and the presentation of potential opportunities, prospective solutions, and future directions in the field of information science and technology"--Provided by publisher.
Download or read book Microbial Biotechnology Principles And Applications 3rd Edition written by Yuan Kun Lee and published by World Scientific Publishing Company. This book was released on 2013-01-30 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly expanding molecular biological techniques and approaches have significant impact on microbial biotechnology, hence the need for the addition of four new chapters in the third edition of this textbook — “Chapter 3: Application of ‘Omics’ Technologies in Microbial Fermentation”, “Chapter 5: Microbial Genome Mining for Identifying Antimicrobial Targets”, “Chapter 21: Bacterial Biofilm: Molecular Characterization and Impacts on Water Management” and “Chapter 23: Microbial Biomining”. “Chapter 15: Transgenic Plants” has been completely revised while most of the other chapters have been thoroughly updated in this new edition.There already exist a number of excellent general textbooks on microbiology and biotechnology that deal with the basic principles of microbial biotechnology. To complement them, this book focuses on the various applications of microbial-biotechnological principles. A teaching-based format is adopted, whereby working problems, as well as answers to frequently asked questions, supplement the main text. The book also includes real life examples of how the application of microbial-biotechnological principles has achieved breakthroughs in both research and industrial production.Although written for polytechnic students and undergraduates, the book contains sufficient information to be used as a reference for postgraduate students and lecturers. It may also serve as a resource book for corporate planners, managers and applied research personnel.
Download or read book Proceedings of 3rd Edition of International conference on Advanced Spectroscopy Crystallography and Applications in Modern Chemistry 2018 written by EuroScicon and published by EuroScicon. This book was released on 2018-05-29 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: June 04-05, 2018 London, UK Key Topics : Chemical Crystallography, Advanced Crystallography, Crystallography Of Novel Materials, Spectroscopy, Spectroscopy Applications, Crystal Growth, Precession Electron Diffraction (PED), Nuclear Magnetic Resonance Crystallography (NMR Crystallography), Electron Crystallography, Recent Development In The X-Ray Studies, Crystallography Applications, Advances In Neutron Diffraction, Biological Structure Determination, Crystallography In Biology, Application Of Modern Chemistry,
Download or read book RESTful Web API Design with Node js 10 Third Edition written by Valentin Bojinov and published by Packt Publishing Ltd. This book was released on 2018-04-30 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: RESTful services have become the standard data feed providers for social services, news feeds, and mobiles. If you want to build fast REST APIs and want to deliver a large amount of data to millions of users, you'll find this book extremely useful. This book will teach you to create scalable RESTful applications based on the Node.js platform.
Download or read book Computing Handbook Third Edition written by Heikki Topi and published by CRC Press. This book was released on 2014-05-14 with total page 1526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computing Handbook, Third Edition: Information Systems and Information Technology demonstrates the richness and breadth of the IS and IT disciplines. The second volume of this popular handbook explores their close links to the practice of using, managing, and developing IT-based solutions to advance the goals of modern organizational environments. Established leading experts and influential young researchers present introductions to the current status and future directions of research and give in-depth perspectives on the contributions of academic research to the practice of IS and IT development, use, and management Like the first volume, this second volume describes what occurs in research laboratories, educational institutions, and public and private organizations to advance the effective development and use of computers and computing in today’s world. Research-level survey articles provide deep insights into the computing discipline, enabling readers to understand the principles and practices that drive computing education, research, and development in the twenty-first century.
Download or read book Principles of political economy with some of their applications to social philosophy written by John Stuart Mill and published by . This book was released on 1852 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Building 360 Degree Information Applications written by Whei-Jen Chen and published by IBM Redbooks. This book was released on 2014-10-01 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today's businesses, applications, social media, and online transactions generate more data than ever before. This data can be explored and analyzed to provide tremendous business value. IBM® WatsonTM Explorer and IBM InfoSphere® Master Data Management (InfoSphere MDM) enable organizations to simultaneously explore and derive insights from enterprise data that was traditionally stored in "silos" in enterprise applications, different data repositories, and in different data formats. This IBM Redbooks® publication provides information about Watson Explorer 9.0, InfoSphere MDM, and IBM InfoSphere MDM Probabilistic Matching Engine for InfoSphere BigInsightsTM (PME for BigInsights). It gives you an overview, describes the architecture, and presents use cases that you can use to accomplish the following tasks: Understand the core capabilities of Watson Explorer, InfoSphere MDM, and PME for BigInsights. Realize the full potential of Watson Explorer applications. Describe the integration and value of the combination of Watson Explorer and InfoSphere MDM. Build a 360-degree information application. Learn by example by following hands-on lab scenarios. /ul>
Download or read book Corporate Legal Compliance Handbook 3rd Edition written by Banks and Banks and published by Wolters Kluwer. This book was released on 2020-06-19 with total page 1976 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corporate Legal Compliance Handbook, Third Edition, provides the knowledge necessary to implement or enhance a compliance program in a specific company, or in a client's company. The book focuses not only on doing what is legal or what is right--the two are both important but not always the same--but also on how to make a compliance program actually work. The book is organized in a sequence that follows how to approach a compliance program. It gives the compliance officer, consultant, or attorney a good grounding in the basics of compliance law. This includes such things as the rules about corporate and individual liability, an understanding of the basics of the key laws that impact companies, and the workings of the U.S. Sentencing Guidelines. Successful programs also require an understanding of educational techniques, good communication skills, and the use of computer tools. The effective compliance program also takes into account how to deliver messages using a variety of media to reach employees in different locations, of different ages or education, who speak different languages. Note: Online subscriptions are for three-month periods.
