Download or read book Antimicrobial Resistance and Therapy in Critically Ill Patients written by Jian-cang Zhou and published by Frontiers Media SA. This book was released on 2023-11-02 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Centers for Disease Control and Prevention of the United States has deemed extended-spectrum β-lactamases (ESBLs)-producing Enterobacterales and multidrug-resistant (MDR) Pseudomonas aeruginosa as serious threats and carbapenem-resistant (CR) Enterobacterales (CRE) and CR Acinetobacter as urgent threats. Due to the prevalent drug resistance of these strains and lack of antimicrobial alternatives, the treatment of infections caused by these MDR Gram-negative pathogens rely on tigecycline, polymyxins (colistin and polymyxin B) or new β-lactam/β-lactamase inhibitor combinations (such as ceftazidime-avibactam, CAZ/AVI). However, the critically ill patients with antimicrobial infection are associated with high mortality. Hence, the prevalence and optimal therapy for critically ill patients with antimicrobial resistance are worth further study.

Download or read book Infection in the Critically Ill an Ongoing Challenge written by H.K.F. van Saene and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume belongs to the series "Topics in Anaethesia and Critical Care", edited by Prof. Antonino Gullo. The titles of this series deal with different topics of critical care medicine. Aim of the volume is to describe the management of infections, in particular, the diagnosis and treatment of pneumonia in the Intensive Care Unit; the book also deals with the management of antimicrobial resistance and on microbiological studies in critically ill patients.

Download or read book Global Antimicrobial Resistance Surveillance System written by World Health Organization and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In May 2015, the Sixty-eighth World Health Assembly adopted the Global action plan on antimicrobial resistance, which reflects the global consensus that AMR poses a profound threat to human health. One of the five strategic objectives of the Global action plan is to strengthen the evidence base through enhanced global surveillance and research. The Global Antimicrobial Resistance Surveillance System (GLASS) has been developed to facilitate and encourage a standardized approach to AMR surveillance globally and in turn support the implementation of the Global action plan on antimicrobial resistance. This manual addresses the early phase of implementation of GLASS, focussing on surveillance of resistance in common human bacterial pathogens. The intended readership of this publication is public health professionals and health authorities responsible for national AMR surveillance. It outlines the GLASS standards and describes the road map for implementation of the system between 2015 and 2019. Further development of GLASS will be based on the lessons learnt during this period"--Publisher's description.

Download or read book Selective Decontamination of the Digestive Tract SDD written by Hans Rommes and published by Springer Nature. This book was released on 2021-03-08 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the basic concepts of Selective Decontamination of the Digestive tract (SDD) to help those involved in treating critically ill patients to improve outcomes and the quality of care. SDD has led to major changes in our understanding, the treatment and prevention of infections in critically ill patients over the past 40 years. It is the most studied intervention in intensive care medicine and is the subject of 73 randomized controlled trials, including over 15000 patients and 15 meta-analyses. SDD reduces morbidity and mortality, is cost-effective and safe as SDD does not increase antimicrobial resistance. Correct application of the SDD strategy enables ICU teams to control infections – even in ICUs with endemic antibiotic resistant microorganisms such as methicillin resistant S. aureus (MRSA). Describing the concept and application of SDD, and presenting case studies and microbiological flow charts, this practical guide will appeal to intensivists, critical care practitioners, junior doctors, microbiologists and ICU-nurses as well as infection control specialists and pharmacists.

Download or read book Continuous Renal Replacement Therapy written by John A. Kellum and published by Oxford University Press. This book was released on 2016 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.

Download or read book Infection Control in the Intensive Care Unit written by Hendrick K.F. van Saene and published by Springer Science & Business Media. This book was released on 2009-11-02 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intensive care is a rapidly changing area of medicine, and after four years from the 2nd edition the volume editors and authors have deemed necessary to update it. In the recent years, in fact, five new randomised controlled trials and five new meta-analyses demonstrate that selective decontamination of the digestive tract [SDD] is an antimicrobial prophylaxis to prevent severe infections of not only lower airways but also of blood. Additionally, SDD has been shown to reduce inflammation including multiple organ failure and mortality. An intriguing observation is the evidence that SDD using parenteral and enteral antimicrobials reduces rather than increases antimicrobial resistance. Moreover, a new chapter on microcirculation had been added. The volume will be an invaluable tool for all those requiring in depth knowledge in the ever expanding field of infection control.

Download or read book Oxford Textbook of Critical Care written by Webb and published by Oxford University Press. This book was released on 2020-01-10 with total page 1961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

Download or read book Antibiotic Pharmacokinetic Pharmacodynamic Considerations in the Critically Ill written by Andrew A. Udy and published by Springer. This book was released on 2017-09-18 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.

Download or read book Core Topics in Cardiothoracic Critical Care written by Kamen Valchanov and published by Cambridge University Press. This book was released on 2018-07-05 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most patients with critical cardiac or thoracic conditions will at some stage pass through the cardiothoracic critical care unit. Critical care presents more complex clinical data than any other area of medicine. The new edition of Core Topics in Cardiothoracic Critical Care focuses on the latest practise in the management of patients in cardiothoracic intensive care. The practice of cardiothoracic critical care medicine is constantly evolving, and this new edition reflects the modernized learning styles for trainees. Each chapter includes key learning points as well as sample multiple choice questions and answers to assist in exam preparation. This edition also features updated chapters on ECMO, perioperative management of patients undergoing emergency cardiothoracic surgery, and advanced modes of organ support for patients. This text provides key knowledge in a concise and accessible manner for trainees, clinicians and consultants from specialities and disciplines such as cardiology and anaesthesia, and nursing and physiotherapy.

Download or read book Empiric Antimicrobial Therapy in Critically Ill Septic Patients written by Ahlem Trifi and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sepsis is a medical emergency and life-threatening condition due to a dysregulated host response to infection, which is time-dependent and associated with unacceptably high mortality. At the bedside of a patient with sepsis or septic shock, clinician must make immediate life-saving decisions including empirical initiation of broad-spectrum antimicrobials; the most likely to be appropriate. The empiric regimen should be initiated within the first hour of diagnosis and determined by assessing patient and epidemiological risk factors, likely source of infection based on presenting signs and symptoms, and severity of illness. Optimizing antibiotic use is crucial to ensure successful outcomes and to reduce adverse antibiotic effects, as well as preventing drug resistance. All likely pathogens involved should be considered to provide an appropriate antibiotic coverage. Herein, we tried to make suggestions of empirical therapeutic regimens in sepsis/septic shock according to most likely pathogens in cause and sepsis source based on the recent recommendations of learned societies. Some suggestions were adapted to an environment of low-resource regions where the ecology of multi drug resistant organisms is of concern.

Download or read book Severe Community Acquired Pneumonia written by Jordi Rello and published by Springer Science & Business Media. This book was released on 2001-06-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe Community Acquired Pneumonia is a book in which chapters are authored and the same topics discussed by North American and European experts. This approach provides a unique opportunity to view the different perspectives and points of view on this subject. Severe CAP is a common clinical problem encountered in the ICU setting. This book reviews topics concerning the pathogenesis, diagnosis and management of SCAP. The discussions on the role of alcohol in severe CAP and adjunctive therapies are important topics that further our understanding of this severe respiratory infection.

Download or read book Antimicrobial Therapy I written by and published by . This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Critical Care Infectious Diseases Textbook written by Jordi Rello and published by Springer. This book was released on 2013-05-09 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections and their complications are a very Additionally, they have a responsibility to ensure important clinical area in the intensive care that nosocomial infections are prevented and unit setting. Community-acquired infections that antimicrobial resistance is minimized by and nosocomial infections both contribute to prudently employing antibiotic agents. It is our the high level of disease acquity common hope that this textbook will provide clinicians among critically ill patients. The importance practicing in the intensive care unit a reference of accurately diagnosing nosocomial infections to help guide their care of infected patients. To and providing appropriate therapies, to include that end we have brought together a group of antimicrobial therapy effective against the international authors to address important topics identified agents of infection, have been shown related to infectious diseases for the critical care to be important determinants of patient practitioner. outcome. Critical care practitioners are in a Jordi Rello, M. D. , Ph. D. unique position in dealing with infectious Jordi Valles, M. D. , Ph. D. diseases. They are often the initial providers of Marin H. Kolle!, M. D. care to seriously ill patients with infections. SECTION 1: GENERAL ASPECTS ]. Rello 1.

Download or read book Infectious Diseases in Critical Care written by Jordi Rello and published by Springer Science & Business Media. This book was released on 2010-05-28 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical care practitioners are often the initial providers of care to seriously ill patients with infections. This book provides clinicians practicing in the intensive care unit with a reference to help guide their care of infected patients. It brings together a group of international authors to address important topics related to infectious diseases for the critical care practitioner.

Download or read book Infectious Diseases and Antimicrobial Stewardship in Critical Care Medicine written by Cheston B. Cunha and published by CRC Press. This book was released on 2020-07-12 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious Diseases and Antimicrobial Stewardship in Critical Care Medicine 4E has been fully updated and revised. The clinical diagnostic approach to common infectious disease problems in the CCU is the underlying theme in the book. Emphasized throughout is the importance of formulating an accurate early presumptive clinical syndromic diagnosis which is the basis for selecting optimal initial antimicrobial therapy in the CCU. Without an accurate presumptive clinical diagnosis, effective therapy is unlikely at best. Based on the most probable clinical diagnosis, optimal antibiotic empiric therapy, based on antimicrobial stewardship principles, minimizes resistance and antibiotic complications in the CCU. This new edition features chapters that explain the tenets of differential diagnostic reasoning, differential diagnostic characteristics of fever patterns in the CCU. The proper interpretation of rapid diagnostic tests, in the appropriate clinical context, is included. The diagnostic importance of cardinal clinical findings, particularly when combined, in the appropriate clinical context is emphasized and remains the basis for clinical problem solving in the CCU. Uniquely, critical diagnostic physical findings in the CCU, including color atlas of diagnostic eye findings, are included as important diagnostic determinants in the CCU. Written by infectious disease clinicians for CCU consultants, Infectious Diseases and Antimicrobial Stewardship in Critical Care Medicine 4E remains a useful evidence based and experience tempered key clinical resource for infectious disease problems in the CCU. Key Features Essentials of the tenets of clinical diagnostic reasoning is explained as it relates to formulating a rapid and accurate clinical syndromic diagnosis in the CCU The diagnostic significance of fever patterns and their relationship to the pulse rate in the proper clinical context is explained in depth as related to the CCU setting Formulating an accurate early clinical syndromic diagnosis is presented as essential since it is the basis of effective empiric antibiotic therapy in the CCU How to combine key non-specific laboratory and imaging findings to increase diagnostic specificity and diagnostic probability in the CCU is presented Clinical perspective on the proper interpretation of the clinical significance of rapid diagnostic test results in the CCU is included A clinical approach to apparent "antibiotic failure" in the CCU is presented either due to actual antibiotic failure or seeming but unrelated non-antibiotic failure Section focuses on the practical aspects of antimicrobial stewardship particularly as related to optimizing dosing effectiveness while minimizing resistance and adverse effects in the CCU

Download or read book Impacts of Antibiotic resistant Bacteria written by and published by U.S. Government Printing Office. This book was released on 1995 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2014 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.