Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. - Presents information in a clear and concise way using a large number of figures - Historical background provides insights on how the process of drug discovery in the anticancer field has evolved - Extensive references to primary literature
Download or read book Human Sexuality and Its Problems written by John Bancroft and published by . This book was released on 1989 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an updated multidisciplinary and scholarly account of the determinants of human sexuality including sexual development, anatomy and physiology, biochemistry and endocrinology of sexual behaviour in addition to sociological and psychological aspects.
Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Download or read book Androgen Deprivation Therapy written by Richard J. Wassersug, PhD and published by Springer Publishing Company. This book was released on 2021-07-12 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for Androgen Deprivation Therapy: "To my knowledge [this] is the only book written in plain language (no medical jargon) explaining what’s happening during ADT, and detailing how to limit and often solve most associated side effects. It should be read by every man undergoing ADT, as well as family members and also healthcare providers. They will find all the details they need to get the most from this treatment..." Prof. N. Mottet, MD, PhD, Urologist, Medical Oncologist, Head of the Prostate Cancer Guidelines panel of the European Association of Urology Androgen Deprivation Therapy is the only guide written exclusively about the side effects of hormone therapy. The authors have collaborated with the European Association of Urology to produce this specially revised new edition to serve men affected by ADT across the globe. This comprehensive workbook for prostate cancer patients and their loved ones is filled with practical advice from experts in the field. The book covers a wealth of strategies to help men cope with ADT and maintain a good quality of life while on this treatment. It is not only an informational manual, but a guide for both patients and partners about ways to make changes in their lives that can keep them healthy and positive when the patient is on ADT. New to this Edition: Updates on the physical side effects of ADT and management strategies Expanded information on exercise and nutrition for men diagnosed with prostate cancer Updates on the primary drugs used to treat prostate cancer and extensive drug tables with common brand names worldwide Revisions throughout based on critical feedback from international medical experts in the field of prostate cancer and related disciplines Exercises, activities, worksheets, and other tools to promote discussion and inspire behavioural changes that can reduce the burden of ADT Officially endorsed by the European Association of Urology
Download or read book Successful Drug Discovery Volume 3 written by János Fischer and published by John Wiley & Sons. This book was released on 2018-06-05 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: With its focus on drugs so recently introduced that they have yet to be found in any other textbooks or general references, the information and insight found here makes this a genuinely unique handbook and reference. Following the successful approach of the previous volumes in the series, inventors and primary developers of successful drugs from both industry and academia tell the story of the drug's discovery and describe the sometimes twisted route from the first drug candidate molecule to the final marketed drug. The 11 case studies selected describe recent drugs ranging across many therapeutic fields and provide a representative cross-section of present-day drug developments. Backed by plenty of data and chemical information, the insight and experience of today's top drug creators makes this one of the most useful training manuals that a junior medicinal chemist may hope to find. The International Union of Pure and Applied Chemistry has endorsed and sponsored this project because of its high educational merit.
Download or read book Molecular Biology of Prostate Cancer written by Manfred Wirth and published by Walter de Gruyter. This book was released on 2013-05-22 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hormone Therapy and Castration Resistance of Prostate Cancer written by Yoichi Arai and published by Springer. This book was released on 2018-05-11 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference expounds the current state of hormone therapy and castration resistance of prostate cancer (PCa). Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy finally forms castration-resistant prostate cancer (CRPC) despite the lack of testicular androgen. With advances in understanding of the molecular basis of hormone dependence and CRPC, many new androgen receptor-targeted agents have emerged. During the last decade, much evidence on hormone therapy has been accumulated in Japan. Interestingly, some of these findings are different from those reported from Western countries, suggesting ethnic variation in the outcome of hormone therapy. In the chapters of this book, expert authors provide exhaustive interpretations of the evidence recently reported from Japan and provide important Asian perspectives on hormone therapy for PCa. This work benefits not only Asian urologists but also their Western counterparts and all physicians and medical personnel who are involved in the treatment of PCa.
Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Download or read book Endocrine Disruption and Human Health written by Philippa D. Darbre and published by Academic Press. This book was released on 2015-03-21 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations
Download or read book Blandy s Urology written by Omar M. Aboumarzouk and published by John Wiley & Sons. This book was released on 2019-05-06 with total page 884 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die 3. Auflage von Blandy?s Urology ist auf dem besten Weg, ein Klassiker zu werden. Die neueste Auflage eines der populärsten Fachbücher der Urologie vereint erfolgreich alles Wissenswerte zur allgemeinen Urologie und Chirurgie in der Urologie für die Zielgruppe der Urologen und Chirurgen. Hauptmerkmal ist die einzigartige Art und Weise von Blandy, urologische Erkrankungen und deren Management zu beschreiben: - Klare, direkte und unkomplizierte Beschreibungen von Krankheiten und Störungen mit Hunderten klinischer Fotos. - Eine Fülle exzellenter Schaubilder zu chirurgischen Eingriffen, die die besten Operationstechniken verdeutlichen. - Legt den Nachdruck auf die häufigsten Erkrankungen in der klinischen Praxis. - Jedes Thema ist einem anatomischen Bereich zugeordnet. Ein Fachbuch, das wegen seines direkten Zugangs zu dem Fachgebiet vor allem von Urologen und angehenden Chirurgen geschätzt wird. Eignet sich auch für die Prüfungsvorbereitung und als Auffrischung
Download or read book Drug induced Ocular Side Effects and Drug Interactions written by Frederick T. Fraunfelder and published by . This book was released on 1982 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Precision Molecular Pathology of Prostate Cancer written by Brian D. Robinson and published by Springer. This book was released on 2018-02-13 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches. The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease. The book consists of five sections which provide insight about the following: (1) General principles; (2) Molecular signatures of primary prostate cancer; (3) Molecular signatures of advanced prostate cancer; (4) Key molecular pathways in prostate cancer development and progression; (5) and Precision medicine approach: Diagnosis, treatment, prognosis. Precision Molecular Pathology of Prostate Cancer is an important resource for the practicing oncologist, urologist, and pathologist, and will also be useful for researchers in the prostate cancer community.
Download or read book Fertility Preservation in Male Cancer Patients written by John P. Mulhall and published by Cambridge University Press. This book was released on 2013-02-21 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by international authorities, this book is aimed at clinicians dealing with male patients rendered infertile by cancer therapy.
Download or read book Practical Medical Oncology Textbook written by Antonio Russo and published by Springer Nature. This book was released on 2021-10-06 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook combines essential information on clinical cancer medicine with a guide to the latest advances in molecular oncology and tumor biology. Providing a systematic overview of all types of solid tumors, including epidemiology and cancer prevention, genetic aspects of hereditary cancers, differential diagnosis, typical signs and symptoms, diagnostic strategies and staging, and treatment modalities, it also discusses new and innovative cancer treatments, particularly targeted therapy and immunotherapy. Expert commentaries at the end of each chapter highlight key points, offer insights, suggest further reading and discuss clinical application using case descriptions. This textbook is an invaluable, practice-oriented tool for medical students just beginning their clinical oncology studies, as well as for medical oncology residents and young professionals.
Download or read book PET CT in Prostate Cancer written by Gary Cook and published by Springer. This book was released on 2017-07-24 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pocket book explains the significant and well-documented impact that PET/CT can have on the management of prostate cancer through the provision of high-quality evidence regarding function and structure. Up-to-date information is supplied on the relevance of PET/CT to diagnosis, treatment planning, and therapy, including the emerging role of PET/CT with PSMA. Readers will also find clear explanation of the relation of the clinical and pathological background to imaging and the value of PET/CT compared with conventional radiological imaging. The book will be an excellent asset for referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings. It is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging, which presents contributions from professionals worldwide who share a common purpose in promoting nuclear medicine as an important imaging specialty for the diagnosis and management of oncological and non-oncological conditions.
Download or read book Pubertal Suppression in Transgender Youth written by Courtney Finlayson and published by Elsevier Health Sciences. This book was released on 2018-08-03 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering current guidelines on the relatively new practice of puberty suppression for gender-dysphoric adolescents, Pubertal Suppression in Transgender Youth provides a succinct, easy-to-digest overview of this timely topic. This concise, clinically-focused resource by Dr. Courtney Finlayson covers all relevant topics, from a brief history of medical care of transgender youth to emerging developments in the field. - Covers the use of gonadotropin-releasing hormone agonist (GnRHa) therapy in transgender youth, including models of care and current treatment guidelines, fertility issues, ethical considerations and the consent process, and more. - Discusses psychosocial, medical, and surgical side effects of treatment. - Consolidates today's available information on this timely topic into one convenient resource.
Download or read book Medical Pharmacology and Therapeutics E Book written by Derek G. Waller and published by Elsevier Health Sciences. This book was released on 2013-08-07 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice
