Download or read book Animal Transgenesis and Cloning written by Louis-Marie Houdebine and published by Wiley-Blackwell. This book was released on 2003-04-02 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to be a concise, balanced introduction to this dynamic subject, covering key issues and current techniques currently used in animal transgenesis and cloning. Provides the essentials of the subject, from the molecular basis of gene structure and function to therapeutic gene cloning in humans. Social and ethical implications of this important area of research are also considered.
Download or read book Animal Transgenesis and Cloning written by Louis-Marie Houdebine and published by Wiley. This book was released on 2003-04-02 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Transgenesis and Cloning is a concise, balanced introduction to this dynamic subject, covering key issues and current techniques currently used in animal transgenesis and cloning. Whilst providing the reader with the essentials of the subject, from the molecular basis of gene structure and function to therapeutic gene cloning in humans, social and ethical implications of this important area of research are also considered. Written in a clear, accessible style, the book starts with an introduction to key molecular biology techniques and in particular, considers techniques used specifically for cloning animals and generating transgenic animals. Later chapters examine the diverse theoretical, technical and ethical issues raised by cloning and transgenesis in both animals and humans. Animal Transgenesis and Cloning: * Is an accessible, concise introduction to this dynamic field * Discusses biological, technical and ethical issues related to cloning and transgenesis * Provides an up-to-date account of the latest research methods and applications. Reviews 'This is a proposal for a book translation in a field that is clearly of importance and very topical. The idea of the book, from gene to transgenic animal, to its uses and abuses is sound and logical ...... It is probable that I would suggest (using) a book similar to the one proposed' Dr Janet Smith, University of Birmingham. 'Chapter one was a tour de force! Very concise and admirably clear ...... I was particularly impressed with the author's 2-page summary of eukaryotic gene regulation, which is no mean achievment!' Dr David de Pomerai, University of Nottingham. '...... I felt that this is a well written, topical book. It covers a lot of ground ...... in my opinion the author manages to provide a satisfying amount of detail and a well focussed treatment of each topic. I like the logic of the book, the fact that it pulls together all of the issues into one readable and manageable text' Dr Brendan Curran, Queen Mary, University of London.
Download or read book Animal Transgenesis and Cloning written by Keywon Frazier and published by Scientific e-Resources. This book was released on 2018-09-27 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transgenic methodologies continue to evolve and have dramatically influenced a cross section of disciplines. They are recognized as instrumental in expanding our understanding of gene expression, regulation and function. This book covers the aspects of gene transfer in animals-from molecular methods to whole animal considerations across a host of species. The book starts with an introduction of what are transgenic animals. Chapter 1 methods and applications related to transgenic application. Chapter 2 describes the Use of Transgenic Animals in Biotechnology as Prospects and Problems. Chapter 3 study about Transgenic Animals in Agriculture. Chapter 4 depicts about the Gene Replacement and Transgenic Animals. This chapter give insight on Specific Sites in Cloned Genes Can Be Altered in Vitro and DNA that can be transferred into Eukaryotic Cells in Various Ways. Chapter 5 discuss about basics of cloning. Chapter 6 tells about the Reproductive Cloning. Chapter 7 tells about the Cloning of Domestic Animals. Chapter 8 depicts about the Surface Epigenetic Reprogramming. Chapters 9 devoted to Animal Health Risks. This chapter focus on the critical biological systems approach to the analysis of clone animal. Chapter 10 describes the development of the Risk Assessment Methodology required for cloning.
Download or read book Animal Transgenesis And Cloning written by Louis Marie Houdebine and published by Turtleback. This book was released on 2003-04-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Transgenesis and Cloning is a concise, balanced introduction to this dynamic subject, covering key issues and current techniques currently used in animal transgenesis and cloning. Whilst providing the reader with the essentials of the subject, from the molecular basis of gene structure and function to therapeutic gene cloning in humans, social and ethical implications of this important area of research are also considered. Written in a clear, accessible style, the book starts with an introduction to key molecular biology techniques and in particular, considers techniques used specifically for cloning animals and generating transgenic animals. Later chapters examine the diverse theoretical, technical and ethical issues raised by cloning and transgenesis in both animals and humans. Animal Transgenesis and Cloning: Is an accessible, concise introduction to this dynamic field Discusses biological, technical and ethical issues related to cloning and transgenesis Provides an up-to-date account of the latest research methods and applications. Reviews 'This is a proposal for a book translation in a field that is clearly of importance and very topical. The idea of the book, from gene to transgenic animal, to its uses and abuses is sound and logical ...... It is probable that I would suggest (using) a book similar to the one proposed' Dr Janet Smith, University of Birmingham. 'Chapter one was a tour de force! Very concise and admirably clear ...... I was particularly impressed with the author's 2-page summary of eukaryotic gene regulation, which is no mean achievment!' Dr David de Pomerai, University of Nottingham. '...... I felt that this is a wellwritten, topical book. It covers a lot of ground ...... in my opinion the author manages to provide a satisfying amount of detail and a well focussed treatment of each topic. I like the logic of the book, the fact that it pulls together all of the issues into one readable and manageable text' Dr Brendan Curran, Queen Mary, University of London.
Download or read book Safety of Genetically Engineered Foods written by National Research Council and published by National Academies Press. This book was released on 2004-07-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
Download or read book Scientific and Medical Aspects of Human Reproductive Cloning written by National Research Council and published by National Academies Press. This book was released on 2002-06-17 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.
Download or read book Animal Biotechnology written by National Research Council and published by National Academies Press. This book was released on 2002-12-29 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.
Download or read book Animal Transgenesis and Cloning Overview of Transgenic Animals CH 2 Use of Transgenic Animals inBiotechnology Prospects and Problems CH 3 Transgenic Animals in Agriculture CH 4 Gene Replacement andTransgenic Animals CH 5 Cloning CH 6 Reproductive Cloning CH 7 Epigenetic Reprogramming CH 8 Cloning of Domestic Animals CH 9 Animal Health Risks CH 10 Developing the RiskAssessment Methodology Bibliography Index written by Keywon Frazier and published by . This book was released on 2018 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Cloning written by Joseph Panno and published by Infobase Publishing. This book was released on 2014-05-14 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the scientific, legal, and ethical issues surrounding animal cloning technology.
Download or read book Transgenic Animals written by Louis-Marie Houdebine and published by CRC Press. This book was released on 2022-04-19 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past 20 years, transgenesis has become a popular technique and a crucial tool for molecular geneticists and biologists. Transgene expression is now better-controlled and even specifically inducible by exogenous factors. While these techniques have quite significantly transformed the experimental approaches taken by biologists, the applications are more limited than expected and concerns have arisen regarding biosafety as well as physiological, social, and philosophical issues. Transgenic Animals: Generation and Use contains articles on the techniques used to generate transgenic animals and a section on the preparation of vectors for the optimally controlled expression of transgenes. It also examines the use of transgenic animals in the study of gene function and human diseases, the preparation of recombinant proteins and organs for pharmaceutical and medical use, and the improvement of genetic characteristics of farm animals. Finally, it discusses more recent problems generated by transgenic animals including conservation of transgenic lines, specific database patenting, biosafety, and bioethics. Drawn from both academia and industry, the contributors to this monograph present in one concise volume all the relevant information on the different aspects of transgenesis. This book can be used as both a reference book and a textbook for specialized university courses and will be of interest to everyone involved in basic research in animal biology, molecular genetics, animal biotechnology, pharmaceutical science, and medicine.
Download or read book Biotechnology in Animal Husbandry written by R. Renaville and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal biotechnology is a broad umbrella encompassing the polarities of fundamental and applied research including molecular modelling, molecular and quantitative genetics, gene manipulation, development of diagnostics and vaccines and manipulation of tissue or digestion metabolism by growth promoters. Although animal biotechnology in the broadest sense is not new, what is new is the level of complexity and precision involved in scientists' current ability to manipulate living organisms. This new book sets out to show that the important ideas in animal biotechnology are exciting and relevant to everyday experience. It represents an important update of the literature for research workers, lecturers, and advisers in animal science, but is also a core text for advanced undergraduate courses in animal science and biotechnology. It will be an essential acquisition for librarians in agriculture and veterinary science.
Download or read book Rabbit Biotechnology written by Louis-Marie Houdebine and published by Springer Science & Business Media. This book was released on 2009-04-24 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.
Download or read book Advanced Protocols for Animal Transgenesis written by Shirley Pease and published by Springer Nature. This book was released on 2011-08-30 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: This laboratory manual, published in cooperation with the International Society for Transgenic Technology (ISTT), provides almost all current methods that can be applied to the creation and analysis of genetically modified animals. The chapters have been contributed by leading scientists who are actively using the technology in their laboratories. Based on their first-hand experience the authors also provide helpful notes and troubleshooting sections. Topics range from standard techniques, such as pronuclear microinjection of DNA, to more sophisticated and modern methods, such as the derivation and establishment of embryonic stem (ES) cell lines, with defined inhibitors in cell culture medium. In addition, related topics with relevance to the field are addressed, including global web-based resources, legal issues, colony management, shipment of mice and embryos, and the three R’s: refinement, reduction and replacement.
Download or read book Transgenic Animals in Agriculture written by James Dickson Murray and published by Cabi. This book was released on 1999 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, a number of advances have been made in genetic engineering as applied to farmed animals. This book has been developed from invited presentations at a conference held in California in August 1997, to address this issue. It is written by representatives from the leading laboratories involved in attempts to improve agriculturally important mammals, poultry and fish. Current knowledge, methodology, technical improvements and successes in the applications of transgenic technology to a range of animals which are important in agriculture are brought together for the first time under one cover. This book is essential reading for research workers in animal genetics, breeding and biotechnology.
Download or read book Transgenic Animal Technology written by Carl A. Pinkert and published by Gulf Professional Publishing. This book was released on 2002-11-18 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: A transgenic animal is one that is genetically modified to carry genes from another species. Transgenic species can be raised to carry potentially useful genes from a variety of species. While the topics of genetic engineering and cloning are controversial, the reality is that these technologies offer tremendous benefits to society - from offering a framework for developing and screening medical therapies, to enhancing the safety and nutrition of the food we eat. One potential application of research into transgenic animal technology is the creation of domestic animals genetically designed to express a certain human disease and therefore serve as models for the study and treatment of human illnesses. Although many mouse models of human diseases are available today, such models in large domestic animals physiologically more similar to humans are sparse and critically needed. Further research in this field will undoubtedly uncover many more direct and indirect benefits of this technology. Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions. This well-illustrated handbook covers the technical aspects of gene transfer - from molecular methods to whole animal considerations - for important laboratory and domestic animal species. It describes methodologies as employed by leading laboratories and is a key resource for researchers, as well as a tool for training technicians and students. This second edition incorporates updates on a variety of genetic engineering technologies ranging from microinjection and ES cell transfer to nuclear transfer in a broad range of animal modeling systems. Contains a comprehensive collection of transgenic animal and gene transfer methods Discusses background and introduction to techniques and animal systems Teaches practical step-by-step protocols New section on analysis
Download or read book Introduction to Pharmaceutical Biotechnology Volume 1 written by Saurabh Bhatia and published by . This book was released on 2018-05-23 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal biotechnology is a broad field including polarities of fundamental and applied research, as well as DNA science, covering key topics of DNA studies and its recent applications. In Introduction to Pharmaceutical Biotechnology, DNA isolation procedures followed by molecular markers and screening methods of the genomic library are explained in detail. Interesting areas such as isolation, sequencing and synthesis of genes, with broader coverage of the latter, are also described. The book begins with an introduction to biotechnology and its main branches, explaining both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It then moves on to the historical development and scope of biotechnology with an overall review of early applications that scientists employed long before the field was defined. Additionally, this book offers first-hand accounts of the use of biotechnology tools in the area of genetic engineering and provides comprehensive information related to current developments in the following parameters: plasmids, basic techniques used in gene transfer, and basic principles used in transgenesis. The text also provides the fundamental understanding of stem cell and gene therapy, and offers a short description of current information on these topics as well as their clinical associations and related therapeutic options.
Download or read book Mammalian and Avian Transgenesis New Approaches written by Shirley Pease and published by Springer Science & Business Media. This book was released on 2007-07-31 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian and Avian Transgenesis presents a collection of novel methods for the production of a wide range of transgenic animals. The manual focuses largely on mice, but also contains protocols for successful transgenesis in rats, cows, pigs and birds. The manual provides detailed, step-by-step protocols covering all aspects of the production of transgenic animals, including the use of lentiviral vectors in gene transfer, intracytoplasmic sperm injection, nuclear transfer, large insert transgenesis, conditional gene expression systems, the use of reporter genes in transgenesis and transgenesis in large animals and birds. The text is supplemented by superb color photos. While the focus is on newly established techniques, the fundamental methods of transgenesis are also covered for those new to the field. Thus this manual is perfectly suited for those wishing to adopt new technologies in transgenesis.
