Download or read book Angiogenesis and Growth Factor Expression in a Model of Transmyocardial Revascularization written by Marc P. Pelletier and published by . This book was released on 2000 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Results. Mortality was similar in both groups (5/25 vs. 8/28, p = NS). Group II had significantly greater vascular density than Group I (5.65 vs. 4.06 vessels/HPF, p
Download or read book Angiogenesis and Direct Myocardial Revascularization written by Roger J. Laham and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: An interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. The authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.
Download or read book Therapeutic Angiogenesis written by J.A. Dormandy and published by Springer. This book was released on 1999-09 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, rapid progress had been made in elucidating the cellular and molecular mechanisms of new blood vessel formation in both health and disease. Lack of sufficient angiogenesis (new capillary development) and collateral formation (remodeling of existing blood vessels) in adult tissues (e. g. , heart, brain, skeletal muscle) during criti cal ischemia has prompted novel therapeutic strategies to stimulate/fa cilitate angiogenesis and collateral formation in ischemic conditions ("therapeutic angiogenesis"). Therapeutic angiogenesis describes a strategy of inducing new col lateral vessels that can bypass vascular obstructions caused by atherosclerotic disease and stimulating new capillaries that can en hance tissue oxygen exchange. Naturally occurring growth factors (e. g. , FGFs, VEGFs) have been identified and demonstrated to induce new blood vessel formation in the adult organism. The therapeutic ap plication of these growth factors has been demonstrated to enhance these natural processes and have been shown in a number of animal models to increase blood flow and oxygen exchange to ischemic tis sues. Therapeutic angiogenesis therefore represents a new medical principle that is anticipated to be used as an adjunct or alternative to angioplasty and/or bypass surgery. A number of strategies have been proposed and tested to deliver growth factors. One strategy is the direct administration of the growth factor protein by intramuscular, intraarte rial or intravenous delivery.
Download or read book Myocardial Laser Revascularization written by Charles Bridges and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finally, there is a dependable guide to transmyocardial laser revasculariztion (TMR). In this groundbreaking volume, clinicians who pioneered the use of this innovative treatment share their insights on the indications, results, mechanisms, and limitations of the technique. Under the careful editorial guidance of Drs. Bridges, Horvath, and Chiu, contributing authors explain: the evolution, science, rationale, and limitations for TMR how to select suitable candidates anesthetic considerations and the role of transesophageal echo TMR as a sole or combination therapy Whether you are already practicing TMR or contemplating its addition to your therapeutic armamentarium, this concise reference will answer all your questions about this important new procedure.
Download or read book State of the Art Surgical Coronary Revascularization written by David P Taggart and published by Oxford University Press. This book was released on 2021-02-04 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: State of the Art Surgical Coronary Revascularization is the most authoritative textbook ever dedicated to the art and science of surgical coronary revascularization, with 71 chapters, organized in 9 sections, and written by over 100 recognized world experts. It covers every aspect of the surgical management of coronary artery pathology and ischaemic heart disease. It provides extensive sections detailing pathophysiology, evaluation and medical and percutaneous management of ischaemic heart disease as well general outcomes and quality assessment for coronary artery bypass grafting (CABG). Pre-, intra- and postoperative management of CABG patients is emphasized in detail as are the core surgical principles in the conduct of CABG, with special focus on the selection of conduits and how to optimize the performance of both on- and off-pump surgery to reduce morbidity and mortality. There are detailed sections on how to improve outcomes with both arterial and venous bypass grafts. This comprehensive textbook also covers in detail less invasive approaches for CABG, CABG in special clinical situations and when CABG is combined with concomitant surgical procedures. In addition to underpinning all chapters with a strong and updated evidence basis, crucial practical surgical techniques are emphasised throughout, making this textbook the indispensable companion of all adult cardiac surgeons and allied health professionals interested in surgical coronary revascularization.
Download or read book Cardiothoracic Surgery Review written by Kenneth L. Franco and published by Lippincott Williams & Wilkins. This book was released on 2012-01-05 with total page 4752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiothoracic Surgery Review covers all of the core knowledge necessary to pass the cardiothoracic boards or the cardiothoracic recertification exam. Each topic presents core information in two-to-four pages and concludes with a brief list of the most important references. The topics cover all areas in cardiothoracic surgery, including cardiac surgery, pediatric cardiac surgery, and thoracic surgery. Included with the book is a companion website featuring the fully searchable text and over 60 procedural videos. This topic-based review is ideal for anyone needing to rapidly reference an up-to-date knowledge base in cardiothoracic surgery, including cardiothoracic fellows, practitioners studying for recertification, and surgical nurses.
Download or read book Lasers in Cardiovascular Interventions written by On Topaz and published by Springer. This book was released on 2015-11-05 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the introduction of laser devices to the medical sciences this technology has created great interest. Specifically, the laser’s unique physical properties and precise bio-tissue interactions render this versatile source of biologic energy an attractive tool for multiple therapeutic purposes in cardiovascular medicine. Over the course of the last 2 decades the utilization of laser technology has become an important component for the management of patients with complex cardiovascular diseases. During this time period, cutting edge laser technology including a variety of wave length generators, newly designed catheters, and a selection of advanced optic fibers have been introduced and applied in the cardiovascular circulation. Improved lasing techniques in the cardiac catheterization suites and operation rooms have been implemented for treatment of ischemic coronary syndromes, peripheral arterial occlusive disease and other atherosclerotic thrombotic conditions. Moreover, during this 20 year time frame, several multicenter and single center clinical studies have been published focusing on the role and utilization of lasers in coronary and peripheral revascularization. And within the rapidly expanding field of interventional cardiac electrophysiology, laser technology has recently revolutionized the management of fractured, abandoned and malfunctioning leads of cardiac pacemakers and automatic defibrillators. Consequently, replacing a notoriously cumbersome and high risk open heart surgery with safe and markedly efficient percutaneous laser based extraction. This textbook will provide the most authoritative, comprehensive and contemporary information covering technological progress, clinical experience and pertinent aspects of laser applications in cardiovascular medicine. It will be of interest to cardiologists, vascular surgeons and interventional radiologist as well as medical students, scientists, biomedical engineering students and graduates.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1844 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sabiston and Spencer s Surgery of the Chest E Book written by Frank Sellke and published by Elsevier Health Sciences. This book was released on 2009-12-16 with total page 2201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through seven successful editions, Sabiston & Spencer Surgery of the Chest has set the standard in cardiothoracic surgery references. Now, the new 8th Edition, edited by Frank W. Sellke, MD, Pedro J. del Nido, MD, and Scott J. Swanson, MD, carries on this tradition with updated coverage of today's essential clinical knowledge from leaders worldwide. Guidance divided into three major sections—Adult Cardiac Surgery, Congenital Heart Surgery, and Thoracic Surgery—lets you quickly find what you need, while new and revised chapters reflect all of the important changes within this rapidly evolving specialty. Expert Consult functionality—new to this edition—enables you to access the complete contents of the 2-volume set from anyplace with an Internet connection for convenient consultation where and when you need it. This is an ideal source for mastering all of the most important current knowledge and techniques in cardiac and thoracic surgery—whether for specialty board review or day-to-day practice. Features short, focused chapters that help you find exactly what you need. Presents the work of international contributors who offer a global view of the entire specialty. Covers thoracic surgery as well as adult and pediatric cardiac surgery for a practical and powerful single source. Includes nearly 1,100 illustrations that help to clarify key concepts. Features online access to the complete contents of the 2-volume text at expertconsult.com for convenient anytime, anywhere reference. Covers the hottest topics shaping today's practice, including the latest theory and surgical techniques for mitral valve disease, advances in the treatment of congenital heart disease, minimally invasive surgical approaches to the treatment of adult and congenital cardiac disease and thoracic disease, stent grafting for aortic disease, and cell-based therapies. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
Download or read book Coronary Artery Disease written by Gregory W. Barsness and published by Springer Science & Business Media. This book was released on 2011-12-07 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: A book directed towards individuals with an interest in the clinical treatment of patients with unrevascularizable angina. It explores the treatment options in the setting of a sound scientific background and provides guidance and predictions for future directions in this rapidly developing field. It is the only textbook of its kind and fulfils an unmet need for practicing internal medicine, family practice and cardiovascular clinicians. It also provides a reliable reference for clinical and basic researchers interested in this topic.
Download or read book Cytokines written by Victor R. Preedy and published by CRC Press. This book was released on 2011-06-24 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytokines are a group of peptides secreted by cells of the immune system such as macrophages, lymphocytes, and T cells. They can be divided into functional families and have-wide ranging impacts that affect cells and molecular pathways to the whole individual. Written by distinguished scholars and experts, this book is a holistic reference to enabl
Download or read book Integrating Cardiology for Nuclear Medicine Physicians written by Assad Movahed and published by Springer Science & Business Media. This book was released on 2008-11-07 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear cardiology is no longer a medical discipline residing solely in nuclear medicine. This is the first book to recognize this fact by integrating in-depth information from both the clinical cardiology and nuclear cardiology literature, and acknowledging cardiovascular medicine as the fundamental knowledge base needed for the practice of nuclear cardiology. The book is designed to increase the practitioner's knowledge of cardiovascular medicine, thereby enhancing the quality of interpretations through improved accuracy and clinical relevance.The text is divided into four sections covering all major topics in cardiology and nuclear cardiology: Basic Sciences and Cardiovascular Diseases Conventional Diagnostic Modalities Nuclear Cardiology Management of Cardiovascular Diseases
Download or read book Cardiac Surgery written by Shahzad G. Raja and published by Springer Nature. This book was released on 2020-02-11 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a succinct overview of cardiac surgery, with key concepts being emphasized throughout. An abundance of illustrations, intra-operative photographs, tables as well as information boxes, aids the reader to visualise, grasp and retain difficult concepts. The inclusion of evidence-based approaches to the management of a range of cardiac surgical conditions equips the reader with an understanding of how to overcome a variety of potentially tough clinical challenges. Concise Cardiac Surgery: A Complete Guide comprehensively covers a range of techniques used in cardiac surgery. It is therefore, an ideal resource for the trainee and practising cardiac surgeon seeking a practically focused text detailing how to apply the latest techniques and evidence-based approaches in their day-to-day practice.
Download or read book Immunopathology in Toxicology and Drug Development written by George A. Parker and published by Springer. This book was released on 2017-03-27 with total page 834 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide organ system–based summaries of spontaneous pathology and common responses to xenobiotics. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 1, Immunobiology, Investigative Techniques, and Special Studies, offers an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays. These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system.
Download or read book Myocardial Revascularization written by George S. Abela and published by Wiley-Liss. This book was released on 2002 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The percutaneous method of transluminal myocardial revascularization has roused enthusiasm in the field of cardiology because it is minimally invasive and relatively inexpensive. In his progressive new book, George Abela, a widely recognized pioneer in cardiology and lasers, has brought together the expertise of international leaders on the subject in this premier reference, Myocardial Revascularization: Novel Percutaneous Approaches. This resource provides interventional cardiologists, technical personnel and nurses in cardiac catheterization labs with the most current scholarly and clinical information available, including: * A historical overview of myocardial revascularization (including the Vineberg procedure and the more recent TMR/PMR procedures) * Biological responses and mechanisms of action in myocardial revascularization using mechanical, laser, ultrasound, and cryoenergy * Current technology for the percutaneous method of the procedure * Descriptions of other novel approaches including percutaneous in situ coronary venous arterialization * Discussion of results from preliminary and advanced TMR/PMR in canine and human procedures * Examination of various catheter navigation systems and potential adjunct gene therapies * Myocyte transplantation to replenish the depleted myocardium * Insights into the economics of these novel percutaneous techniques
Download or read book Lasers for Ischemic Heart Disease written by Xavier M. Mueller and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the growing age of the population, the proportion of elderly patients with diffuse coronary artery disease and severe comorbidities is increasing. The characteristics of these patients render them unsuitable for currently recognized revascularization procedures (CABG, PTCA). Therefore, there is an urgent need for new treatment modalities which could alleviate their symptoms and increase blood flow to the ischemic myocardium, while being less invasive for their fragile condition. The aim of this book is to provide an anatomical and physiological background as well as a complete review of the alternative methods of revascularization which are under development, namely transmyocardial laser revascularization, therapeutic angiogenesis and neurostimulation.
Download or read book Interventional Cardiology written by Howard C. Herrmann and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of nonsurgical treatment for a variety of heart diseases that affect the cardiac valves, the heart muscle, and the structure of the heart. The authors describe who these procedures are useful for, how to do them, and how well they work. Major topics of discussion include percutaneous techniques for valvular heart disease, septal defects at both the atrial and ventricular levels, adjunctive therapies during coronary interventions, and angioplasty to treat extracardiac vascular disease, as well as reviews of the cutting-edge imaging modalities now being used in interventional procedures. An accompanying CD-ROM contains video demonstrations of catheterization and and the imaging portions of these procedures.
