Download or read book Angiogenesis and Direct Myocardial Revascularization written by Roger J. Laham and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: An interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. The authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.
Download or read book Angiogenesis and Direct Myocardial Revascularization 2005 written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The AHA Clinical Cardiac Consult written by J. V. Nixon and published by Lippincott Williams & Wilkins. This book was released on 2010-10-18 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ideal source of fast, reliable guidance on diagnosis and management of both common and rare cardiovascular problems, this handbook covers more than 170 problems, diseases, syndromes, and chief complaints in the popular, easy-to-read, two-page 5-Minute Consult format.
Download or read book Essentials of Restenosis written by Henricus J. Duckers and published by Springer Science & Business Media. This book was released on 2007-11-13 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading interventional cardiologists, including Patrick Serruys, provide the gold-standard reference on the treatment of restenosis for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field, cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy.
Download or read book Coronary Artery Disease written by Gregory W. Barsness and published by Springer Science & Business Media. This book was released on 2011-12-06 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: A book directed towards individuals with an interest in the clinical treatment of patients with unrevascularizable angina. It explores the treatment options in the setting of a sound scientific background and provides guidance and predictions for future directions in this rapidly developing field. It is the only textbook of its kind and fulfils an unmet need for practicing internal medicine, family practice and cardiovascular clinicians. It also provides a reliable reference for clinical and basic researchers interested in this topic.
Download or read book Nuclear Cardiology The Basics written by Frans J Th Wackers and published by Springer Science & Business Media. This book was released on 2007-12-26 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to provide the outline for the "nuts and bolts" establishment and operation of a nuclear cardiology laboratory. In so doing, the authors have attempted to deal with the relevant issues that a laboratory director must address in either setting up the laboratory or maintaining its competitive edge and clinical competence over time. The authors primarily attempted to identify issues related to outpatient imaging facilities. However, where appropriate issues related to inpatients in hospital-based laboratories are also discussed.
Download or read book The Art and Science of Cardiac Physical Examination written by Narasimhan Ranganathan and published by Springer Science & Business Media. This book was released on 2007-11-10 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been our experience that instruction in physical examination of the heart in medical schools has been deteriorating since the advent of such modern diagnostic tools as two-dimensional echocardiography and nuclear imaging. At best, the teaching has been sketchy and too superficial for the student to appreciate the pathophysiological correlates. Both invasive and the noninvasive modern technologies have contributed substantially to our knowledge and understanding of cardiac physical signs and their pathophysiological correlates. However, both students and teachers alike appear to be mesmerized by technological advances to the neglect of the age-old art, as well as the substantial body of science, of cardiac physical examination. It is also sad to see reputed journals give low priority to articles related to the clinical examination. Our experience is substantiated by a nationwide survey of internal medicine and cardiology training programs, which concluded that the teaching and practice of cardiac auscultation received low emphasis, and perhaps other bedside diagnostic skills as well (1). The state of the problem is well reflected in the concerns expressed in previous publications (2–4), including the 2001 editorial in the American Journal of Medicine (Vol. 110, pp. 233–235), entitled “Cardiac auscultation and teaching rounds: how can cardiac auscultation be resuscitated?”, as well as in the rebuttal, “Selections from current literature. Horton hears a Who but no murmurs—does it matter?” (5).
Download or read book Heart Disease Diagnosis and Therapy written by M. Gabriel Khan and published by Springer Science & Business Media. This book was released on 2007-10-27 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. Gabriel Khan, MD, concisely assembles in a reader friendly format all the clinically useful information that an internist needs in both his daily rounds and abusy office practice to find correct clinical diagnoses and choose optimal pharmacologic therapies for their patients. Highlights include a simplified method for recognition of, and a practical therapeutic approach to, arrhythmias, as well as a more logical approach to drug management of hypertension than that given by the Joint National Committee, instructive algorithms that simplify the diagnosis and treatment of syncope, and extensive diagnostic information on hypertrophic cardiomyopathy. A large number of illustrative electrocardiograms that help to clarify the most often misinterpreted of all cardiologic tests and extensive discussions of practical cardiovascular pharmacology complete this magisterial survey.
Download or read book Stem Cells and Myocardial Regeneration written by Marc S. Penn and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 5 years there has been great excitement and controversy in the scientific, financial, and lay literature for the potential of stem cell-based strategies for the prev- tion and treatment of chronic heart failure (CHF). Not that long ago we believed we were born with a set number of cardiac myocytes and that once damaged there was no hope to replace them. The interest in the field stems from the magnitude of cardiovascular disease in the world. Our ability to treat and help patients survive acute myocardial infarction (MI) has resulted in a near epidemic of CHF. There are more than 5 million Americans who currently carry the diagnosis of CHF. With more than 1 million MIs a year in the United States, there are approx 500,000 new cases of CHF diagnosed each year. The goal of Stem Cells and Myocardial Regeneration is to present, in a coherent manner, the current state of knowledge of stem cell-based therapies for cardiac dysfunction, including current findings in both the laboratory and the clinic trials. The first section of this Stem Cells and Myocardial Regeneration focuses on the magnitude of the problem and the successes and failures of what we consider optimal medical therapy. It is on this background that stem cell-based therapy needs to build.
Download or read book Principles of Molecular Cardiology written by Marschall S. Runge and published by Springer Science & Business Media. This book was released on 2007-11-14 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.
Download or read book Essential Echocardiography written by Scott D. Solomon and published by Springer Science & Business Media. This book was released on 2007-11-15 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the premier practical guide to understanding echocardiography. The perfect marriage between anatomy and physiology, the text covers emerging cardiac imaging technologies, advances in ultrasound technology, as well as new techniques and applications of cardiac ultrasound.
Download or read book Handbook of Complex Percutaneous Carotid Intervention written by Jacqueline Saw and published by Springer Science & Business Media. This book was released on 2008-08-17 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook supplements hands-on training in interventional cardiology with a specific focus on percutaneous intervention in patients with extracranial carotid artery stenosis. It carries reviews of landmark studies supporting carotid endarectomy and stenting and is a comprehensive guide to this exciting and burgeoning field.
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Cardiovascular Disease in the Elderly written by Gary Gerstenblith and published by Springer Science & Business Media. This book was released on 2007-11-03 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: A panel of clinicians, researchers, and leaders in the field review and discuss the latest findings on the pathophysiology, diagnosis, and management of cardiovascular disease in the older patient. The authors explain the physiological changes associated with the normal aging process that may lead to the development of disease, to adverse consequences once disease develops, and which alter the risk-benefit equation for medical and other interventions designed to diagnose, assess, and treat cardiovascular disease. The focus is on particularly common syndromes in the elderly, including cardiac failure with normal ejection fraction, isolated systolic hypertension, and atrial fibrillation. Wherever possible, the authors take an evidence-based approach to recommendations and rely heavily on prospective clinical trials.
Download or read book Cardiovascular MRI written by Peter G. Danias and published by Springer Science & Business Media. This book was released on 2008-04-06 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Magnetic Resonance (CMR) is a rapidly evolving imaging technology and is now increasingly utilized in patient care. Its advantages are noninvasiveness, superb image resolutions, and body tissue characterization. CMR is now an essential part of both cardiology and radiology training and has become part of the examination for Board certification. This book provides a condensed but comprehensive and reader friendly educational tool for cardiology fellows and radiology residents. It contains multiple choice questions similar to board examinations with concise comment and explanation about the correct answer.
Download or read book Angiogenesis Assays written by Carolyn A. Staton and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.
Download or read book Interventional Cardiology written by Howard C. Herrmann and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of nonsurgical treatment for a variety of heart diseases that affect the cardiac valves, the heart muscle, and the structure of the heart. The authors describe who these procedures are useful for, how to do them, and how well they work. Major topics of discussion include percutaneous techniques for valvular heart disease, septal defects at both the atrial and ventricular levels, adjunctive therapies during coronary interventions, and angioplasty to treat extracardiac vascular disease, as well as reviews of the cutting-edge imaging modalities now being used in interventional procedures. An accompanying CD-ROM contains video demonstrations of catheterization and and the imaging portions of these procedures.
