Download or read book An Introduction to the Interpretation of Quantal Responses in Biology written by Paul Soames Hewlett and published by Hodder Education. This book was released on 1979 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: The typical dose-response cure. The probit and similar transformations. The logit transformation. Calculations in probit analysis. Calculations in logit analysis. Quantal responses to mixtures of drugs. Dose-response curves from heterogeneous populations and detection of resistance in insects. Time and response. The general nature of quantal response.
Download or read book An Introduction to the Interpretation of Quantal Responses in Biology written by Paul Soames Hewlett and published by . This book was released on 1979 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: The typical dose-response cure. The probit and similar transformations. The logit transformation. Calculations in probit analysis. Calculations in logit analysis. Quantal responses to mixtures of drugs. Dose-response curves from heterogeneous populations and detection of resistance in insects. Time and response. The general nature of quantal response.
Download or read book Analysis of Quantal Response Data written by Byron J.T. Morgan and published by Routledge. This book was released on 2018-12-13 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes the standard methods as the starting point, and then describes a wide range of relatively new approaches and procedures designed to deal with more complicated data and experiments - including much recent research in the area. Throughout mention is given to the computing requirements - facilities available in large computing packages like BMDP, SAS and SPSS are also described.
Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
Download or read book Water the Environment written by Rose and published by CRC Press. This book was released on 2017-12-14 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compilation of papers provides useful insights on the differing approaches to water quality and the diversity of strategies in water quality management worldwide. Considering the current situation and looking to the future, the aim of this publication is to provide a sensible addition to the literature by concentrating on several important aspects of water and the environment.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Introducing Quantitative Geography written by Larry O'Brien and published by Routledge. This book was released on 2005-10-09 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of quantitative geography is to train geographers in numeracy and in the vital skills of data collection, processing and interpretation. Introducting Quantitative Geography describes quantification from first principles to cover all the key elements of quantitative geography. No previous knowledge of statistical procedures is assumed. Worked examples and computer analyses are used to explain measurement, scale, description, models and modelling. Building on this, the book explores and clarifies the intellectual and practical problems presented by numerical and technological advances in the field.
Download or read book Seeds 3rd Edition written by Robert S Gallagher and published by CABI. This book was released on 2013-12-06 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 3rd edition of Seeds: The Ecology of Regeneration in Plant Communities highlights the many advances in the field of seed ecology and its relationship to plant community dynamics that have taken place in recent years. The new edition also features chapters on seed development and morphology, seed chemical ecology, implications of climate change on regeneration by seed, and the functional role of seed banks in agricultural and natural ecosystems. The book is aimed at advanced level students and researchers in the fields of seed science, seed ecology and plant ecology.
Download or read book Dose Response Analysis Using R written by Christian Ritz and published by CRC Press. This book was released on 2019-07-19 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays the term dose-response is used in many different contexts and many different scientific disciplines including agriculture, biochemistry, chemistry, environmental sciences, genetics, pharmacology, plant sciences, toxicology, and zoology. In the 1940 and 1950s, dose-response analysis was intimately linked to evaluation of toxicity in terms of binary responses, such as immobility and mortality, with a limited number of doses of a toxic compound being compared to a control group (dose 0). Later, dose-response analysis has been extended to other types of data and to more complex experimental designs. Moreover, estimation of model parameters has undergone a dramatic change, from struggling with cumbersome manual operations and transformations with pen and paper to rapid calculations on any laptop. Advances in statistical software have fueled this development. Key Features: Provides a practical and comprehensive overview of dose-response analysis. Includes numerous real data examples to illustrate the methodology. R code is integrated into the text to give guidance on applying the methods. Written with minimal mathematics to be suitable for practitioners. Includes code and datasets on the book’s GitHub: https://github.com/DoseResponse. This book focuses on estimation and interpretation of entirely parametric nonlinear dose-response models using the powerful statistical environment R. Specifically, this book introduces dose-response analysis of continuous, binomial, count, multinomial, and event-time dose-response data. The statistical models used are partly special cases, partly extensions of nonlinear regression models, generalized linear and nonlinear regression models, and nonlinear mixed-effects models (for hierarchical dose-response data). Both simple and complex dose-response experiments will be analyzed.
Download or read book Understanding Drug Action written by Peter J. Rice and published by Amer Pharmacists Assn. This book was released on 2013-11-11 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Drug Action: An Introduction to Pharmacology provides readers with a survey of the scientific understanding of drug action. This readable introduction to pharmacology is simple enough to be understood without having to take a class to follow the material, but can also be used to complement a course in pharmacology. The approach to pharmacology is at a basic scientific level to build a framework of how drugs work supplemented with information on some representative drugs that are used clinically. Each chapter includes review questions and many chapters include tables of important drugs with brand and generic names.
Download or read book Handbook on the Toxicology of Metals Specific metals written by Lars Friberg and published by Elsevier Science & Technology. This book was released on 1986 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.
Download or read book Seeds written by J. Bewley and published by Springer. This book was released on 2012-12-06 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of our monograph on seed physiology and biochemistry (The Physiology and Biochemistry of Seeds in Relation to Germination, Sprin ger-Verlag, 1978, 1982), it has been suggested to us that a text covering the same subject area would be appropriate. This book is our response. Unlike the previous volumes, however, this text is not intended to be either a critical or a comprehensive account. Instead it is a more generalized consideration of the essential aspects of seed physiology and biochemistry as we see them. It also includes a substantial amount of new and different material. In a work of this sort it is inevitable that some simplifications must be made, but we hope, never theless, that we have presented the most reasonable conspectus of areas of con troversy and uncertainty. In this respect, literature citations have been kept to a minimum and do not interrupt the text; they are placed at the end of each chapter and are intended to be used as a source for further references. We hope that this book will be of value to students and teachers in uni versities, colleges, and other institutes of higher learning whose courses include plant biology. Although it is particularly appropriate for studies of seed biol ogy, it should also find broader applications in general plant physiology, agri culture, and horticulture.
Download or read book Urologic Oncology written by Herbert Lepor and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology text books are generally out of the date. Single papers in specialized journals are informative but seldom comprehensive; these are often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in depth reviews of cancer topics, and published symposium lectures are often the best overviewes available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. it is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genito urinary cancer, pediatric oncology, etc. Second, by asking eminent authori ties in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each optic and tumor type is covered in a volume appear ing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Download or read book Subject Catalog written by Library of Congress and published by . This book was released on 1979 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biopharmaceutical Applied Statistics Symposium written by Karl E. Peace and published by Springer. This book was released on 2018-09-03 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This BASS book Series publishes selected high-quality papers reflecting recent advances in the design and biostatistical analysis of biopharmaceutical experiments – particularly biopharmaceutical clinical trials. The papers were selected from invited presentations at the Biopharmaceutical Applied Statistics Symposium (BASS), which was founded by the first Editor in 1994 and has since become the premier international conference in biopharmaceutical statistics. The primary aims of the BASS are: 1) to raise funding to support graduate students in biostatistics programs, and 2) to provide an opportunity for professionals engaged in pharmaceutical drug research and development to share insights into solving the problems they encounter. The BASS book series is initially divided into three volumes addressing: 1) Design of Clinical Trials; 2) Biostatistical Analysis of Clinical Trials; and 3) Pharmaceutical Applications. This book is the third of the 3-volume book series. The topics covered include: Targeted Learning of Optimal Individualized Treatment Rules under Cost Constraints, Uses of Mixture Normal Distribution in Genomics and Otherwise, Personalized Medicine – Design Considerations, Adaptive Biomarker Subpopulation and Tumor Type Selection in Phase III Oncology Trials, High Dimensional Data in Genomics; Synergy or Additivity - The Importance of Defining the Primary Endpoint, Full Bayesian Adaptive Dose Finding Using Toxicity Probability Interval (TPI), Alpha-recycling for the Analyses of Primary and Secondary Endpoints of Clinical Trials, Expanded Interpretations of Results of Carcinogenicity Studies of Pharmaceuticals, Randomized Clinical Trials for Orphan Drug Development, Mediation Modeling in Randomized Trials with Non-normal Outcome Variables, Statistical Considerations in Using Images in Clinical Trials, Interesting Applications over 30 Years of Consulting, Uncovering Fraud, Misconduct and Other Data Quality Issues in Clinical Trials, Development and Evaluation of High Dimensional Prognostic Models, and Design and Analysis of Biosimilar Studies.
Download or read book Population Ecology of Individuals MPB 25 Volume 25 written by Adam Lomnicki and published by Princeton University Press. This book was released on 2020-03-31 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: A common tendency in the field of population ecology has been to overlook individual differences by treating populations as homogeneous units; conversely, in behavioral ecology the tendency has been to concentrate on how individual behavior is shaped by evolutionary forces, but not on how this behavior affects population dynamics. Adam Lomnicki and others aim to remedy this one-sidedness by showing that the overall dynamical behavior of populations must ultimately be understood in terms of the behavior of individuals. Professor Lomnicki's wide-ranging presentation of this approach includes simple mathematical models aimed at describing both the origin and consequences of individual variation among plants and animals. The author contends that further progress in population ecology will require taking into account individual differences other than sex, age, and taxonomic affiliation--unequal access to resources, for instance. Population ecologists who adopt this viewpoint may discover new answers to classical questions of population ecology. Partly because it uses a variety of examples from many taxonomic groups, this work will appeal not only to population ecologists but to ecologists in general.
Download or read book Multiple Chemical Interactions written by Edward J. Calabrese and published by CRC Press. This book was released on 1990-12-19 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: This classic work on a vitally important and new topic contains over 1200 pages of complete information on chemical interactions as it pertains to environmental and medical concerns. It illustrates principles of interactions so you will have the conceptual basis for predicting responses to complex environmental mixtures-apply it to specific situations-theoretical and practical. To date, environmental standards regulate the effects of a single pollutant. Multiple Chemical Interactions is exhaustive coverage of how the multitude of chemicals in our world interact with human health. This book gives us critically new and complete data on an emerging field that will be of interest to all environmental scientists, environmental and public health professionals, toxicologists, industrial hygienists, regulators and libraries.
