Download or read book An Artificial Intelligence Framework for the Automated Segmentation and Quantitative Analysis of Retinal Vasculature written by Ali Hatamizadeh and published by . This book was released on 2020 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: The reliable segmentation and quantification of retinal vasculature can provide the means to diagnose and monitor the progression of a variety of diseases affecting the blood vessel network, including diabetes and hypertension. In this thesis, we address this problem in depth, leveraging the power of artificial intelligence to devise automated approaches for the segmentation and width estimation of vessels in two ophthalmological image modalities. First, we investigate the automated segmentation of retinal vessels in color fundus images. We propose a novel, fully convolutional deep neural network with an encoder-decoder architecture that employs dilated spatial pyramid pooling with multiple dilation rates to recover the lost content in the encoder and add multiscale contextual information to the decoder. We also propose a simple yet effective way of quantifying and tracking the widths of retinal vessels through direct use of the segmentation predictions. The proposed methodology takes a whole-image approach and is tested on two publicly available datasets, DRIVE and CHASE-DB1. Second, we introduce the first deep-learning based method for the semantic segmentation of retinal arteries and veins in infrared imaging along with a novel dataset dubbed AVIR, and propose an innovative encoder-decoder that is regularized by variational autoencoders. Additionally, our method automatically quantifies the morphological changes of the segmented arteries and veins, which is important for establishing automated vessel tracking systems.

Download or read book Artificial Intelligence in Ophthalmology written by Andrzej Grzybowski and published by Springer Nature. This book was released on 2021-10-13 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a wide-ranging overview of artificial intelligence (AI), machine learning (ML) and deep learning (DL) algorithms in ophthalmology. Expertly written chapters examine AI in age-related macular degeneration, glaucoma, retinopathy of prematurity and diabetic retinopathy screening. AI perspectives, systems and limitations are all carefully assessed throughout the book as well as the technical aspects of DL systems for retinal diseases including the application of Google DeepMind, the Singapore algorithm, and the Johns Hopkins algorithm. Artificial Intelligence in Ophthalmology meets the need for a resource that reviews the benefits and pitfalls of AI, ML and DL in ophthalmology. Ophthalmologists, optometrists, eye-care workers, neurologists, cardiologists, internal medicine specialists, AI engineers and IT specialists with an interest in how AI can help with early diagnosis and monitoring treatment in ophthalmic patients will find this book to be an indispensable guide to an evolving area of healthcare technology.

Download or read book Automated Delineation and Quantitative Analysis of Blood Vessels in Retinal Fundus Image written by Xiayu Xu and published by . This book was released on 2012 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Automated fundus image analysis plays an important role in the computer aided diagnosis of ophthalmologic disorders. A lot of eye disorders, as well as cardiovascular disorders, are known to be related with retinal vasculature changes. Many studies has been done to explore these relationships. However, most of the studies are based on limited data obtained using manual or semi-automated methods due to the lack of automated techniques in the measurement and analysis of retinal vasculature. In this thesis, a fully automated retinal vessel width measurement technique is proposed. This novel method models the accurate vessel boundary delineation problem in two-dimension into an optimal surface segmentation problem in threedimension. Then the optimal surface segmentation problem is transformed into finding a minimum-cost closed set problem in a vertex-weighted geometric graph. The problem is modeled differently for straight vessel and for branch point because of the different conditions in straight vessel and in branch point. Furthermore, many of the retinal image analysis needs the location of the optic disc and fovea as a prerequisite information, for example, in the analysis of the relationship between vessel width and the distance to the optic disc. Hence, a simultaneous optic disc and fovea detection method is presented, which includes a two-step classification of three classes. The major contributions of this thesis include: 1) developing a fully automated vessel width measurement technique for retinal blood vessels, 2) developing a simultaneous optic disc and fovea detection method, 3) validating the methods using multiple datasets, and 4) applying the proposed methods in multiple retinal vasculature analysis studies.

Download or read book Automated Analysis of Fluorescein Angiography of the Human Retina written by Rubiel Vargas Canas and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis presents an automated framework for quantitative analysis of fluorescein angiographies of the human retina. Such framework represents the core of a computer-aided system, which can assist NHS clinicians in early diagnosis of macular degeneration (AMD). The presented methodology aims to demonstrate the technical feasibility of automated extraction of retinal blood flow parameters, and results in a step forward in the development of an automated computer vision system for quantitative analysis of fluorescein angiograms to assist NHS clinicians in early diagnosis of AMD. The approach commences by segmenting the anatomic constituent parts of the ocular fundus, i.e. the optic disc (OD), the fovea and the vascular network tree. The OD/fovea are simultaneously detected by combining luminance information and geometric information from the major blood vessels; information regarding OD/fovea is then used for delineating the macula. Meanwhile, to segment the retinal vasculature, three independent approaches are implemented. These approaches use information about maximum curvature in both image- and frequency-domains. Such information is combined, firstly, using a supervised linear classifier. Secondly, utilising a committee of local experts, where each expert is represented by an artificial neural network. A fuzzy clustering algorithm is used for expert selection based on the specific input pattern. The output of the system is determined through a winner-takes-all rule. And finally. by considering a tracing algorithm that follows vessel centrelines and walls using a set of rules based upon information of maximum curvature and symmetry. Following segmentation, the extracted vasculature is utilised as input features for a multi modal registration algorithm, which has its fundamentals on the Fourier transform and a parametric estimation based on the gradient of the quadratic error function and least squares computation. Once subsequent frames of the angiogram have been aligned, anatomic, morphologic and sequential analyses are carried out. Special attention is given to the latter one, which is a methodology for quantitative analysis of retinal haemodynamics. It analyses retinal blood flow based on the estimation of parameters such as mean transit-time (MTT) and vascular volume. The former parameter is estimated using densitometry and analysis of the vascular response; the latter is calculated from the lumen of extracted vessels. The performance of the framework is demonstrated on a comprehensive dataset, which contains images of normal retinas and retinas with pathologies such as wet age-related macular degeneration and branch retinal vein occlusion. Results achieved in certain individual modules overcame serious defects observed in previous methods.

Download or read book Artificial Intelligence in Medical Imaging written by Erik R. Ranschaert and published by Springer. This book was released on 2019-01-29 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a thorough overview of the ongoing evolution in the application of artificial intelligence (AI) within healthcare and radiology, enabling readers to gain a deeper insight into the technological background of AI and the impacts of new and emerging technologies on medical imaging. After an introduction on game changers in radiology, such as deep learning technology, the technological evolution of AI in computing science and medical image computing is described, with explanation of basic principles and the types and subtypes of AI. Subsequent sections address the use of imaging biomarkers, the development and validation of AI applications, and various aspects and issues relating to the growing role of big data in radiology. Diverse real-life clinical applications of AI are then outlined for different body parts, demonstrating their ability to add value to daily radiology practices. The concluding section focuses on the impact of AI on radiology and the implications for radiologists, for example with respect to training. Written by radiologists and IT professionals, the book will be of high value for radiologists, medical/clinical physicists, IT specialists, and imaging informatics professionals.

Download or read book Artificial Intelligence Applications in Chronic Ocular Diseases written by Wei Chi and published by Frontiers Media SA. This book was released on 2024-04-23 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the acceleration of urbanization and aging processes, chronic ocular diseases have become a critical threat to the vision health of the global population . Chronic ocular diseases include a series of disorders and conditions that involve long-term defects in both anterior and posterior segments of the eye, such as cataract, glaucoma, keratoconus (KC), diabetic retinopathy (DR), and age-related macular degeneration (AMD). However, it is still challenging to understand the mechanisms of these diseases and to discover new and reliable biomarkers to identify the diseases and their severities. Moreover, conventional methods in clinical societies are not as effective or efficient as expected, especially in the era of artificial intelligence.

Download or read book Web Microanalysis of Big Image Data written by Peter Bajcsy and published by Springer. This book was released on 2018-01-22 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book looks at the increasing interest in running microscopy processing algorithms on big image data by presenting the theoretical and architectural underpinnings of a web image processing pipeline (WIPP). Software-based methods and infrastructure components for processing big data microscopy experiments are presented to demonstrate how information processing of repetitive, laborious and tedious analysis can be automated with a user-friendly system. Interactions of web system components and their impact on computational scalability, provenance information gathering, interactive display, and computing are explained in a top-down presentation of technical details. Web Microanalysis of Big Image Data includes descriptions of WIPP functionalities, use cases, and components of the web software system (web server and client architecture, algorithms, and hardware-software dependencies). The book comes with test image collections and a web software system to increase the reader's understanding and to provide practical tools for conducting big image experiments. By providing educational materials and software tools at the intersection of microscopy image analyses and computational science, graduate students, postdoctoral students, and scientists will benefit from the practical experiences, as well as theoretical insights. Furthermore, the book provides software and test data, empowering students and scientists with tools to make discoveries with higher statistical significance. Once they become familiar with the web image processing components, they can extend and re-purpose the existing software to new types of analyses. Each chapter follows a top-down presentation, starting with a short introduction and a classification of related methods. Next, a description of the specific method used in accompanying software is presented. For several topics, examples of how the specific method is applied to a dataset (parameters, RAM requirements, CPU efficiency) are shown. Some tips are provided as practical suggestions to improve accuracy or computational performance.

Download or read book Explainable and Interpretable Models in Computer Vision and Machine Learning written by Hugo Jair Escalante and published by Springer. This book was released on 2018-11-29 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles leading research on the development of explainable and interpretable machine learning methods in the context of computer vision and machine learning. Research progress in computer vision and pattern recognition has led to a variety of modeling techniques with almost human-like performance. Although these models have obtained astounding results, they are limited in their explainability and interpretability: what is the rationale behind the decision made? what in the model structure explains its functioning? Hence, while good performance is a critical required characteristic for learning machines, explainability and interpretability capabilities are needed to take learning machines to the next step to include them in decision support systems involving human supervision. This book, written by leading international researchers, addresses key topics of explainability and interpretability, including the following: · Evaluation and Generalization in Interpretable Machine Learning · Explanation Methods in Deep Learning · Learning Functional Causal Models with Generative Neural Networks · Learning Interpreatable Rules for Multi-Label Classification · Structuring Neural Networks for More Explainable Predictions · Generating Post Hoc Rationales of Deep Visual Classification Decisions · Ensembling Visual Explanations · Explainable Deep Driving by Visualizing Causal Attention · Interdisciplinary Perspective on Algorithmic Job Candidate Search · Multimodal Personality Trait Analysis for Explainable Modeling of Job Interview Decisions · Inherent Explainability Pattern Theory-based Video Event Interpretations

Download or read book Ocular Fluid Dynamics written by Giovanna Guidoboni and published by Springer Nature. This book was released on 2019-11-25 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters in this contributed volume showcase current theoretical approaches in the modeling of ocular fluid dynamics in health and disease. By including chapters written by experts from a variety of fields, this volume will help foster a genuinely collaborative spirit between clinical and research scientists. It vividly illustrates the advantages of clinical and experimental methods, data-driven modeling, and physically-based modeling, while also detailing the limitations of each approach. Blood, aqueous humor, vitreous humor, tear film, and cerebrospinal fluid each have a section dedicated to their anatomy and physiology, pathological conditions, imaging techniques, and mathematical modeling. Because each fluid receives a thorough analysis from experts in their respective fields, this volume stands out among the existing ophthalmology literature. Ocular Fluid Dynamics is ideal for current and future graduate students in applied mathematics and ophthalmology who wish to explore the field by investigating open questions, experimental technologies, and mathematical models. It will also be a valuable resource for researchers in mathematics, engineering, physics, computer science, chemistry, ophthalmology, and more.

Download or read book Medical Imaging Informatics written by Alex A.T. Bui and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Imaging Informatics provides an overview of this growing discipline, which stems from an intersection of biomedical informatics, medical imaging, computer science and medicine. Supporting two complementary views, this volume explores the fundamental technologies and algorithms that comprise this field, as well as the application of medical imaging informatics to subsequently improve healthcare research. Clearly written in a four part structure, this introduction follows natural healthcare processes, illustrating the roles of data collection and standardization, context extraction and modeling, and medical decision making tools and applications. Medical Imaging Informatics identifies core concepts within the field, explores research challenges that drive development, and includes current state-of-the-art methods and strategies.

Download or read book The Computer Graphics Manual written by David Salomon and published by Springer Science & Business Media. This book was released on 2011-09-18 with total page 1559 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a broad overview of computer graphics (CG), its history, and the hardware tools it employs. Covering a substantial number of concepts and algorithms, the text describes the techniques, approaches, and algorithms at the core of this field. Emphasis is placed on practical design and implementation, highlighting how graphics software works, and explaining how current CG can generate and display realistic-looking objects. The mathematics is non-rigorous, with the necessary mathematical background introduced in the Appendixes. Features: includes numerous figures, examples and solved exercises; discusses the key 2D and 3D transformations, and the main types of projections; presents an extensive selection of methods, algorithms, and techniques; examines advanced techniques in CG, including the nature and properties of light and color, graphics standards and file formats, and fractals; explores the principles of image compression; describes the important input/output graphics devices.

Download or read book Automated Image Detection of Retinal Pathology written by Herbert Jelinek and published by CRC Press. This book was released on 2009-10-09 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses the Effect of Automated Assessment Programs on Health Care ProvisionDiabetes is approaching pandemic numbers, and as an associated complication, diabetic retinopathy is also on the rise. Much about the computer-based diagnosis of this intricate illness has been discovered and proven effective in research labs. But, unfortunately, many of

Download or read book Artificial Intelligence in Medical Imaging written by Lia Morra and published by CRC Press. This book was released on 2019-11-25 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Choice Recommended Title, January 2021 This book, written by authors with more than a decade of experience in the design and development of artificial intelligence (AI) systems in medical imaging, will guide readers in the understanding of one of the most exciting fields today. After an introductory description of classical machine learning techniques, the fundamentals of deep learning are explained in a simple yet comprehensive manner. The book then proceeds with a historical perspective of how medical AI developed in time, detailing which applications triumphed and which failed, from the era of computer aided detection systems on to the current cutting-edge applications in deep learning today, which are starting to exhibit on-par performance with clinical experts. In the last section, the book offers a view on the complexity of the validation of artificial intelligence applications for commercial use, describing the recently introduced concept of software as a medical device, as well as good practices and relevant considerations for training and testing machine learning systems for medical use. Open problematics on the validation for public use of systems which by nature continuously evolve through new data is also explored. The book will be of interest to graduate students in medical physics, biomedical engineering and computer science, in addition to researchers and medical professionals operating in the medical imaging domain, who wish to better understand these technologies and the future of the field. Features: An accessible yet detailed overview of the field Explores a hot and growing topic Provides an interdisciplinary perspective

Download or read book Unsupervised Learning written by Geoffrey Hinton and published by MIT Press. This book was released on 1999-05-24 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its founding in 1989 by Terrence Sejnowski, Neural Computation has become the leading journal in the field. Foundations of Neural Computation collects, by topic, the most significant papers that have appeared in the journal over the past nine years. This volume of Foundations of Neural Computation, on unsupervised learning algorithms, focuses on neural network learning algorithms that do not require an explicit teacher. The goal of unsupervised learning is to extract an efficient internal representation of the statistical structure implicit in the inputs. These algorithms provide insights into the development of the cerebral cortex and implicit learning in humans. They are also of interest to engineers working in areas such as computer vision and speech recognition who seek efficient representations of raw input data.

Download or read book Computational Retinal Image Analysis written by Emanuele Trucco and published by Academic Press. This book was released on 2019-11-19 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Retinal Image Analysis: Tools, Applications and Perspectives gives an overview of contemporary retinal image analysis (RIA) in the context of healthcare informatics and artificial intelligence. Specifically, it provides a history of the field, the clinical motivation for RIA, technical foundations (image acquisition modalities, instruments), computational techniques for essential operations, lesion detection (e.g. optic disc in glaucoma, microaneurysms in diabetes) and validation, as well as insights into current investigations drawing from artificial intelligence and big data. This comprehensive reference is ideal for researchers and graduate students in retinal image analysis, computational ophthalmology, artificial intelligence, biomedical engineering, health informatics, and more. Provides a unique, well-structured and integrated overview of retinal image analysis Gives insights into future areas, such as large-scale screening programs, precision medicine, and computer-assisted eye care Includes plans and aspirations of companies and professional bodies

Download or read book Medical Imaging Concepts Methodologies Tools and Applications written by Management Association, Information Resources and published by IGI Global. This book was released on 2016-07-18 with total page 2118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging has transformed the ways in which various conditions, injuries, and diseases are identified, monitored, and treated. As various types of digital visual representations continue to advance and improve, new opportunities for their use in medical practice will likewise evolve. Medical Imaging: Concepts, Methodologies, Tools, and Applications presents a compendium of research on digital imaging technologies in a variety of healthcare settings. This multi-volume work contains practical examples of implementation, emerging trends, case studies, and technological innovations essential for using imaging technologies for making medical decisions. This comprehensive publication is an essential resource for medical practitioners, digital imaging technologists, researchers, and medical students.

Download or read book Geometric Modeling for Scientific Visualization written by Guido Brunnett and published by Springer Science & Business Media. This book was released on 2003-11-17 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Geometric Modeling and Scientific Visualization are both established disciplines, each with their own series of workshops, conferences and journals. But clearly both disciplines overlap; this observation led to the idea of composing a book on Geometric Modeling for Scientific Visualization.