Download or read book Allogeneic Hematopoetic Stem Cell Transplantation for Children with Acute Lymphoblastic Leukemia in the Era of Immunotherapy written by Christina Peters and published by Frontiers Media SA. This book was released on 2022-09-27 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Download or read book The EBMT Handbook written by Nicolaus Kröger and published by . This book was released on 2020-10-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Download or read book Allogeneic Hematopoietic Stem Cell Transplantation from Unrelated Donors is Associated with Higher Infection Rates in Children with Acute Lymphoblastic Leukemia a Prospective International Multicenter Trial on Behalf of the BFM SG and the EBMT PDWP written by Herbert Pichler and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Severe infections (SI) significantly impact on non-relapse mortality after hematopoietic stem cell transplantation (HSCT). We assessed 432 children and adolescents with acute lymphoblastic leukemia (ALL) after total body irradiation based myeloablative HSCT within the multicenter ALL-BFM-SCT 2003 trial for SI grade 3 or higher according to common terminology criteria for adverse events. A total 172 patients experienced at least one SI. Transplantation from matched unrelated donors (MUD) was associated with any type of SI in the pre-engraftment period (hazard ratio [HR]: 2.57; P
Download or read book Basics of Hematopoietic Stem Cell Transplant written by Sanjeev Kumar Sharma and published by Springer Nature. This book was released on 2023-07-24 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is quick guide on the hematopoietic stem cell transplant (SCT), also called bone marrow transplant (BMT) - an evolving field of hematology and hemato-oncology. This book covers the various types of stem cell transplants like autologous and allogeneic stem cell transplants, indications, ways of doing a transplant, and stem cell transplants basic principles. Written in a question-answer format, readers will find it more interesting as one question sequentially leads to another. This book explains the complications of SCT in individual chapters along with the biology of T cells which are the most important cells involved in the success of SCT This book is beneficial to the budding hematologists, oncologists, and postgraduates interested in SCT and helps students in their exams. The book would be helpful for readers globally as SCT is a procedure done worldwide and is an ever-increasing field for treating various benign and malignant hematological diseases.
Download or read book Haploidentical Transplantation written by Stefan O. Ciurea and published by Springer. This book was released on 2018-05-03 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty.
Download or read book Stem Cell Transplantation for Hematologic Malignancies written by Robert J. Soiffer and published by . This book was released on 2014-01-15 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances In Pediatric Hematopoietic Cell Therapies And Transplantation written by Emmanuel Katsanis and published by Frontiers Media SA. This book was released on 2022-02-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr Patrick Hanley, a Topic Editor for this collection, is a co-founder and serves on the board of directors of Mana Therapeutics, a private biotech company focused on cellular therapy for AML. All other Topic Editors declare no competing interests with regards to the Research Topic.
Download or read book Hematopoietic Cell Transplantation in Children with Cancer written by Franklin O. Smith and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers future directions. The authors are all internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric diseases that are treatable with blood and marrow transplantation and will prove invaluable to specialists, generalists, and trainees alike.
Download or read book The European Blood and Marrow Transplantation Textbook for Nurses written by Michelle Kenyon and published by Springer. This book was released on 2018-03-14 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.
Download or read book Hematopoietic Stem Cell Transplantation written by Michael R. Bishop and published by Springer Science & Business Media. This book was released on 2009-09-25 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dogmas of the quiet past are inadequate to the stormy present. The occasion is piled high with difficulty, and we must rise with the occasion. As our case is new, so we must think anew and act anew. Abraham Lincoln, 1862 When I came across this quote, it made me recall my first participation at an international meeting on bone marrow transplantation, at a time when this was the only term that was used to describe the field. During a particular session there was a presentation on the use of peripheral blood as the sole source of stem cells for transplantation, and a member of the audience rose to state that it was medically unethical to consider such treatment, as it certainly could not contain stem cells. Now nearly twenty years later, peripheral blood is the predominant source of stem cells used for hematopoietic stem cell transplantation. In the same period of time there have been several other dogmatic opinions, which permeate all of medicine, that have come and gone in the field of hematopoietic stem cell transplantation, and will continue to do so with advancements from basic and clinical research. It is within this context that the format of this book was devised. Traditionally reviews on specific topics related to hematopoietic stem cell transplantation reflect the views of a single author or a research group.
Download or read book The EBMT Handbook written by Anna Sureda and published by Springer Nature. This book was released on with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunotherapy for Pediatric Malignancies written by Juliet C. Gray and published by Springer. This book was released on 2017-11-21 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of current immunotherapy strategies, and how these may be applicable to childhood cancers. The first part of the book reviews how the immune system recognizes cancer, and the various escape mechanisms allowing tumour growth. The importance of the tumor microenvironment and the challenges this may present to achieving effective immunotherapy are discussed. Monoclonal antibodies, cellular, cytokine and vaccine therapies are all comprehensively reviewed, with particular focus on their potential application to pediatric cancers. Practical aspects of delivering such therapies to children, likely toxicities and potential biomarkers are considered. Finally, consideration is given to how, in the longer term, such therapies may be combined with conventional therapies such as chemotherapy and radiotherapy. Edited by two distinguished pediatric oncologists with a collection of chapters from the most authoritative experts in cancer immunotherapy, this is an indispensable volume for pediatric oncologists and physicians working in childhood cancer care.
Download or read book Prognostic Markers in Hematologic Oncology written by Wojciech Gorczyca and published by CRC Press. This book was released on 2005-12-20 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effective treatment of the tumors of the hematopoietic system now often depends on an exact prognosis for the disorder concerned, and so the hematopathologist can give vital direction to the hematologic or oncologic clinician. Prognostic Markers in Hematologic Oncology comprehensively presents the numerous predictive and prognostic parameters in the practice of oncologic haematology and underlines their clinical relevance.
Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Download or read book Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist Oncologist written by Valerie I. Brown and published by Springer. This book was released on 2017-12-22 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive and state-of-the-art review on pediatric hematopoietic stem cell transplantation (HSCT). The book covers such topics as graft versus host disease (GVHD), HSC mobilization, stem cell selection, and HSCT-relevant laboratory assays and techniques. The text is specially formatted so that the scientific basis of HSCT and ethical considerations are integrated into the relevant clinical framework. Each chapter also includes diagrams, illustrations, and tables that summarize key points and concepts that can be used as a quick visual reference for the reader. Written by experts in the field, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist is a valuable resource on pediatric HSCT suited for pediatric hematologists-oncologists, fellows, advanced practitioners, clinical nurses, and other referring physicians.
Download or read book Stem Cells in Clinical Practice and Tissue Engineering written by Rakesh Sharma and published by BoD – Books on Demand. This book was released on 2018-05-02 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.
