Download or read book Recent Advances in Psychiatry from Psycho Neuro Immunology Research Autoimmunencephalitis Autoimmune Encephalopathy Mild Encephalitis written by Karl Bechter and published by Frontiers Media SA. This book was released on 2019-08-12 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growing evidence derived from cerebrospinal fluid (CSF), neuropathological, imaging, genetic, and epidemiological studies link neuroinflammation and immune dysregulation to a subset of individuals with a variety of severe mental disorders (SMDs), including affective and non-affective psychotic disorders. Further, the recent discoveries of neuronal surface antibodies (NSAs) in autoimmune encephalitis (AE) presenting with diverse neuropsychiatric disorders such as psychosis and cognitive decline, among many others, provides further support to the notion that CNS autoimmunity and neuroinflammation can contribute to the neurobiology of psychiatric disturbances. Further, these immune mechanisms may contribute to a subset of patients currently diagnosed as having treatment-resistant SMDs such as schizophrenia and major depressive disorder. Additionally, mounting data indicate that various infections can serve as an immunological trigger of aberrant immune responses, presumably by causing release of excess neural antigen, thereby giving rise to NSAs or aberrant immune cellular responses to give rise to primary or secondary psychiatric disorders such as schizophrenia and those associated with AE, respectively. Collectively, these findings support the “mild encephalitis” hypothesis of SMD. The significant overlap among AE-associated psychosis, systemic autoimmune disorder-associated psychosis, and psychotic disorders associated with pathological processes involving inflammation and immune dysregulation has also prompted some authors to adopt the term “autoimmune psychosis” (AP). This term reflects that this psychosis subtype is mechanistically linked to complex neuroimmune and inflammatory signalling abnormalities that can be responsive to early immunomodulatory treatment. It also suggests that a subset of AP might represent an incomplete or “forme fruste” subtype of AE presenting with dominant or pure psychiatric symptoms mimicking primary psychiatric illnesses. Because data indicate that delayed diagnosis and treatment may lead to permanent sequelae, early recognition of AP utilizing neurodiagnostic workup (e.g., CSF analysis, neuroimaging, and EEG) and its early treatment with appropriate immunotherapy are paramount to a meaningful recovery. This eBook will provide an overview of the current knowledge and research areas from epidemiology, risk factors and diagnosis to the management of these conditions, in this rapidly emerging field, helping to bridge the gaps in knowledge that currently exist in the disciplines of Psychiatry, Neurology, and Neuroimmunology.

Download or read book Genetics of Colorectal Cancer written by John D. Potter and published by Springer. This book was released on 2008-12-08 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.

Download or read book Computers and Games for Mental Health and Well Being written by Yasser Khazaal and published by Frontiers Media SA. This book was released on 2018-07-12 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen important developments in the computer and game industry, including the emergence of the concept of serious games. It is hypothesized that tools such as games, virtual reality, or applications for smartphones may foster learning, enhance motivation, promote behavioral change, support psychotherapy, favor empowerment, and improve some cognitive functions. Computers and games may create supports for training or help people with cognitive, emotional, or behavioral change. Games take various formats, from board games to informatics to games with interactive rules of play. Similarly, computer tools may vary widely in format, from self-help or assisted computerized training to virtual reality or applications for smartphones. Some tools that may be helpful for mental health were specifically designed for that goal, whereas others were not. Gamification of computer-related products and games with a numeric format tend to reduce the gap between games and computers tools and increase the conceptual synergy in such fields. Games and computer design share an opportunity for creativity and innovation to help create, specifically design, and assess preventive or therapeutic tools. Computers and games share a design conception that allows innovative approaches to overcome barriers of the real world by creating their own rules. Yet, despite the potential interest in such tools to improve treatment of mental disorders and to help prevent them, the field remains understudied and information is under-disseminated in clinical practice. Some studies have shown, however, that there is potential interest and acceptability of tools that support various vehicles, rationales, objectives, and formats. These tools include traditional games (e.g., chess games), popular electronic games, board games, computer-based interventions specifically designed for psychotherapy or cognitive training, virtual reality, apps for smartphones, and so forth. Computers and games may offer a true opportunity to develop, assess, and disseminate new prevention and treatment tools for mental health and well-being. Currently, there is a strong need for state-of-the-art information to answer questions such as the following: Why develop such tools for mental health and well-being? What are the potential additions to traditional treatments? What are the best strategies or formats to improve the possible impact of these tools? Are such tools useful as a first treatment step? What is the potential of a hybrid model of care that combines traditional approaches with games and/or computers as tools? What games and applications have already been designed and studied? What is the evidence from previous studies? How can such tools be successfully designed for mental health and well-being? What is rewarding or attractive for patients in using such treatments? What are the worldwide developments in the field? Are some protocols under development? What are the barriers and challenges related to such developments? How can these tools be assessed, and how can the way that they work, and for whom, be measured? Are the potential benefits of such products specific, or can these additions be attributed to nonspecific factors? What are the users’ views on such tools? What are the possible links between such tools and social networks? Is there a gap between evidence-based results and market development? Are there any quality challenges? What future developments and studies are needed in the field?

Download or read book Health Psychology written by Hymie Anisman and published by SAGE. This book was released on 2021-04-07 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a thorough biopsychosocial approach, Health Psychology is your ideal companion to studying this subject. Exploring bio-social, developmental and lifestyle factors and how these relate to physical and psychological disturbances, this lively and approachable guide takes you through this key topic for psychology, health sciences, nursing and education students. Using case studies and up to date research, the author brings to life the important practical applications in this area, helping you to understand the varied ways the biological, physiological and social factors affect psychology and how effective interventions can influence the health of a population.

Download or read book Tourette s Syndrome Tics Obsessions Compulsions written by James F. Leckman and published by John Wiley & Sons. This book was released on 1998-11-09 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Früher wurde das Tourette-Syndrom (TS) als seltene Störung betrachtet; mittlerweile jedoch wurde erkannt, daß TS häufig in der Kindheit beginnt. Man weiß jetzt auch, daß die Anfälligkeit für TS über Generationen hinweg vererbt wird. Diagnose, Genetik, Phänomenologie, Geschichte und Behandlung von TS werden hier dargestellt, ausgehend von einem einmaligen Ansatz, der Beziehungen zwischen der Störung und dem normalen Entwicklungsweg herstellt. (8/98)

Download or read book Dyslexia Learning and the Brain written by Roderick Nicolson and published by MIT Press. This book was released on 2010-08-13 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique overview of research on dyslexia and an account of the underlying causes at cognitive, brain, and neural system levels that provides a framework for significant progress in the understanding of dyslexia and other related learning disabilities. Dyslexia research has made dramatic progress since the mid-1980s. Once discounted as a “middle-class myth,” dyslexia is now the subject of a complex—and confusing—body of theoretical and empirical research. In Dyslexia, Learning, and the Brain, leading dyslexia researchers Roderick Nicolson and Angela Fawcett provide a uniquely broad and coherent analysis of dyslexia theory. Unlike most dyslexia research, which addresses the question “what is the cause of the reading disability called dyslexia?” the authors' work has addressed the deeper question of “what is the cause of the learning disability that manifests as reading problems?” This perspective allows them to place dyslexia research within the much broader disciplines of cognitive psychology and cognitive neuroscience and has led to a rich framework, including two established leading theories, the automatization deficit account (1990) and the cerebellar deficit hypothesis (2001). Nicolson and Fawcett show that extensive evidence has accumulated to support these two theories and that they may be seen as subsuming the established phonological deficit account and sensory processing accounts. Moving to the explanatory level of neural systems, they argue that all these disorders reflect problems in some component of the procedural learning system, a multiregion system including major components of cortical and subcortical regions. The authors' answer to the fundamental question “what is dyslexia?” offers a challenge and motivation for research throughout the learning disabilities, laying the foundations for future progress.

Download or read book Science and Conservation in the Galapagos Islands written by Stephen J. Walsh and published by Springer Science & Business Media. This book was released on 2012-12-05 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this launch of the Galapagos series, this book provides a broad “framing” assessment of the current status of social and ecological systems in the Galapagos Islands, and the feedback that explicitly links people to the environment. It also highlights the challenges to conservation imposed by tourism in the Galapagos Islands and the attendant migration of people from mainland Ecuador to service the burgeoning tourism industry. Further, there is an emphasize on the status of the terrestrial and marine environments that form the very foundation of the deep attraction to the Islands by tourists, residents, scholars, and conservationists.

Download or read book A Frequency Dictionary of German written by Randall Jones and published by Routledge. This book was released on 2015-06-03 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Frequency Dictionary of German is an invaluable tool for all learners of German, providing a list of the 4,034 most frequently used words in the language. Based on a 4.2 million-word corpus which is evenly divided between spoken, fiction and non-fiction texts, the dictionary provides a detailed frequency-based list plus alphabetical and part of speech indexes. All entries in the rank frequency list feature the English equivalent, a sample sentence plus an indication of major register variation. The dictionary also contains twenty-one thematically organized lists of frequently used words on a variety of topics as well as eleven special vocabulary lists. A Frequency Dictionary of German aims to enable students of all levels to maximize their study of German vocabulary in an efficient and engaging way.

Download or read book Decisions of the Commission written by United States. Federal Communications Commission and published by . This book was released on 1940 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Prevention and Early Detection of Colorectal Cancer written by Graeme P. Young and published by W.B. Saunders Company. This book was released on 1996 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an overview of the issues involved in prevention and early detection of colorectal cancer providing up-to-date, practical advice for clinicians. Possible management strategies for those at risk are provided, taking into account the biological principles of colorectal cancer development, epidemiological data and emerging genetic information, as well as social and environmental factors.

Download or read book The Genetic Basis of Human Cancer written by Kenneth W. Kinzler and published by McGraw Hill Professional. This book was released on 2002 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: -- Current coverage of diagnosis and treatment on a wide spectrum of active cancer research.

Download or read book Physiological Basis of Occupational Health written by Keizō Shiraki and published by . This book was released on 1996 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nanotheranostics For Personalized Medicine written by Patrick Couvreur and published by World Scientific. This book was released on 2016-02-22 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome.Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine.This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field.

Download or read book Renal Pathophysiology written by J. Gary Abuelo and published by . This book was released on 1989 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Annenbergs written by John E. Cooney and published by Simon & Schuster. This book was released on 1982 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is the colorful and dramatic biography of two of America's most controversial entrepreneurs: Moses Louis Annenberg, 'the racing wire king, ' who built his fortune in racketeering, invested it in publishing, and lost much of it in the biggest tax evasion case in United States history; and his son, Walter, launcher of TV Guide and Seventeen magazines and former ambassador to Great Britain."--Jacket.

Download or read book Laboratory Diagnosis and Monitoring of Diabetes Mellitus written by P. -Kanagasabapathy A. -Reinauer H. C-Home Heuck and published by . This book was released on 2003-01-01 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper discusses the essential role of the laboratory in the diagnosis and management of diabetes mellitus.