Download or read book Albumin in Medicine written by Masaki Otagiri and published by Springer. This book was released on 2016-11-01 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.
Download or read book All About Albumin written by Theodore Peters Jr. and published by Academic Press. This book was released on 1995-12-21 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, All About Albumin summarizes the chemistry, genetics, metabolism, clinical implications, and commercial aspects of albumin. It provides the most up-to-date sequences, structures, and compositions of many species, and includes more than 2000 references. - Includes up-to-date sequences, structures, and compositions of many species - Reviews the protein chemistry, genetic control, and metabolism of albumin - Covers medical and cell culture applications in vivo and in vitro, with a section on handling albumin in the laboratory - Presents the relationship of albumin to its superfamily with an updated scheme for their evolution - First complete coverage of all aspects of serum albumin in one volume, with more than 2000 references
Download or read book Albumin Structure Function and Uses written by Victor M. Rosenoer and published by Elsevier. This book was released on 2014-05-18 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed. This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism. This monograph should be a useful resource for biochemists and clinicians.
Download or read book Sustainable Agriculture Reviews 43 written by Ankit Saneja and published by Springer Nature. This book was released on 2020-05-05 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book comprises of eight chapters dealing on various aspects of pharmaceutical technology for delivery of natural products. Book chapters deal with the solubility and bioavailability enhancement technologies for natural products. Emphasis has also been given on the significance of delivery strategies for improving the therapeutic efficacy of paclitaxel, galantamine and tea constituents.
Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.
Download or read book Monitoring and Intervention for the Critically Ill Small Animal written by Rebecca Kirby and published by John Wiley & Sons. This book was released on 2016-12-19 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monitoring and Intervention for the Critically Ill Small Animal: The Rule of 20 offers guidance for assessing the patient, interpreting diagnostic test results, and selecting appropriate monitoring procedures. Based on Rebecca Kirby’s time-tested Rule of 20, with a chapter devoted to each item on the checklist Provides comprehensive guidance for monitoring a critically ill small animal patient Emphasizes the interplay of each parameter with one another Designed for fast access on the clinic floor, with potentially life-saving ideas, tips, lists and procedures Presents tables, schematics, algorithms, and drawings for quick reference
Download or read book Fluid Therapy for the Surgical Patient written by Christer H. Svensen and published by CRC Press. This book was released on 2018-03-22 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, there have been a large number of important studies related to fluid management for the surgical patient, resulting in confusion on this critical aspect of patient care. Proper fluid therapy in the perioperative setting has always been important but has only recently had concrete outcome-based guidelines. This is the first comprehensive, up-to-date and practical summary book on the topic.
Download or read book Human Serum Albumin HSA written by Travis Stokes and published by Nova Science Publishers. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Serum Albumin (HSA) is the most abundant plasma protein. It has been widely used for drug delivery systems and has recently emerged as a versatile carrier for therapeutic agents against diabetes, cancer and infectious diseases. This book provides an overview of the expanding field of preclinical and clinical applications and developments that use albumin as a carrier of drug delivery systems. The authors' discuss the properties of drug binding sites within the structure of HSA, discuss new possibilities for the therapeutic potential of HSA and analyze recently reported HSA-drug complexes including HSA-antibody conjugates. Novel investigations on the applications of albumin fusion proteins are discussed as well, with a focus on tumor targeting and intracellular delivery. Other chapters examine the different aspects of albumin glycation and oxidation, the changes in the structure of human serum albumin determined from infrared spectroscopy and a review of CAPIDAN, a special fluorescent dye, which attaches to drug binding sites of human serum albumin.
Download or read book Bovine Serum Albumin written by Martin A. Masuelli and published by . This book was released on 2020-01-07 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serum albumin is a large protein present in cow serum protein (BSA, Bovine Serum Albumin) rich in essential amino acids and compounds with disulfide bridges and thiol groups. This protein passes into breast milk from the bloodstream by diffusion, has antioxidant capacity and protects fats from oxidation. Albumin has the ability to inhibit tumor factors and bind to fat, mobilize them in the body to perform other functions such as obtaining energy or forming membranes. It is also able to block the conversion of angiotensin I into angiotensin II (vasoconstrictor) which gives it antihypertensive action. In addition, it has the ability to reduce cholesterol absorption, complex heavy metals and is an opioid agonist (acts on opioid receptors and promotes analgesia). BSA is the most studied and produced protein worldwide in the last 80 years. This protein brings large dividends to the world economy with a very prominent and favorable annual growth at a cost of 100 USD per gram. This book brings new contributions to the science and industry of this biopolymer. The audience of this book is very wide from students, teachers and researchers (doctors, pharmacists, biochemists and industrialists of this sector). Therefore, this book has a great future and many readers to whom it is addressed.
Download or read book Human Serum Albumin written by Dianne Cohen and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human serum albumin is found in the intravascular and extracellular space and is the main protein of human blood plasma. Human serum albumin binds water, cations (such as Ca2+, Na+, K+), fatty acids, hormones, bilirubin, thyroxin (T4) and pharmaceuticals. Structurally, the serum albumins are similar, each domain containing five or six internal disulfide bonds. In the opening chapter of Human Serum Albumin: Structure, Binding and Activity the authors review, the structure, content and binding of HSA.Then, the role of albumin in free radical trapping activities and as an oxyradical scavenger is described. A discussion of recent advances in the use of the antioxidant properties of human serum albumin to make drugs detectable in vivo is also presented.Human serum albumin has one tryptophan residue and shows a characteristic fluorescence of around 350 nm under ultraviolet irradiation. Because tryptophan is easily oxidized by reactive oxygen species and/or photoexcited molecules through electron transfer (leading to fluorescence diminishment) a fluorometry of this tryptophan residue is a useful tool to evaluate oxidation. In light of these characteristics, the authors examine the photosensitizing activity of organic photosensitizers, including porphyrins and phenothiazine dyes.The use of magnetic resonance imaging and spectroscopy for the determination of human serum albumin structure, drug binding and in vivo activity is explored, in addition to drug modifications using human serum albumin.Following this, this compilation studies the major approaches for the characterization of human serum albumin as a fluorinated drug delivery agent and fluorinated albumin influence on drug binding. Synthesis and characterization of fluorinated conjugates of albumin and adsorbed human serum albumin on surfaces containing CF3 are also discussed.The concluding study investigates possible similarities and differences in albumin concentration and the presence of tyrosine in urine from a population of healthy and microalbuminuria dependent women. The assessment of subtle changes in albumin concentration, the primary macromolecular component of urine, is critical for the diagnosis of early stage albuminuria, one of the major complications in nephropathy.
Download or read book Volume Replacement written by Joachim Boldt and published by . This book was released on 2004 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is not another attempt to create a "cook book" on volume replacement of fluid substitution. This book, in contrast, summarizes the up-to-date-knowledge of this topic presented by experts from a wide range of disciplines. Everybody caring for the critically ill will profit from the different chapters at different levels - nurses, students, residents, consultants, and even experts on volume therapy.
Download or read book Drug Guide written by F a Davis and published by . This book was released on 2021-06-17 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: #1 DRUG BOOK for Nursing Students! "This is the perfect drug book for nursing school! All the information on the meds is in-depth and all that you need to know."-Abby W. SAFETY FIRST! Davis's Drug Guide for Nurses(R), Seventeenth Edition delivers all the information you need to administer medications safely across the lifespan-well-organized monographs for hundreds of generic and thousands of trade-name drugs. FREE DIGITAL ACCESS Redeem the access code to unlock your one-year, free subscription to DrugGuide.com, Davis's Drug Guide Online, powered by Unbound Medicine. You'll have access to more than 1,700 monographs from your desktop, laptop, or any mobile device with a web browser. Search the complete 5,000-drug database and appendices quickly and efficiently. Build your knowledge with extensively cross-referenced drugs. Keep up to date with FDA drug news. LIFE-SAVING GUIDANCE ... AT A GLANCE New! The AGS Beers Criteria for Potentially Inappropriate Medication Use in Older Adults #1 Drug Guide for patient safety Red tab for high alert medications, plus in-depth high alert and patient safety coverage Red, capitalized letters for life-threatening side effects REMS (Risk Evaluation and Mitigation Strategies) icon Drug-drug, drug-food, drug-natural product interactions Special considerations for patient populations. Geri heading identifies special concerns for older adults. OB and Lact headings highlight information for pregnant and breastfeeding patients. Pedi heading identifies concerns for children. Rep heading identifies considerations for patients of reproductive age. IV Administration subheads Pharmacogenomic content Canadian-specific content In-depth guidance for patient and family teaching FREE LEARNING, CARE PLANNING, AND PATIENT EDUCATION TOOLS Online at FADavis.com Audio Library of 1,200+ drug names help you pronounce important terms Two tutorials, each with a self-test Preventing Medication Errors Psychotropic Drugs Easy-to-Use Calculators Body mass index (BMI) Metric conversions IV drip rates Dosage/KG Fahrenheit/Celsius Interactive Case Studies - brief, real-life scenarios that are followed by a series of questions Audio podcasts delivering information on... Risk Evaluation Mitigation Systems (REMS) How to use Davis's Drug Guide for Nurses(R) Detecting and managing ADRs Evidence-based practice and Pharmacotherapeutics Pharmacogenomics Medication errors Special dosing considerations Educating patients about Safe Medication Use Video clips illustrating the safe administration of medications ONLINE REVIEWS OF THE 16TH EDITION OF DAVIS'S DRUG GUIDE FOR NURSES Five Stars. "I LOVE that this includes nursing interventions, patient teaching and an online access code. Highly recommend."-E.G. Accurate and up to date. "Top notch for nursing students! Includes many things other drug guides l
Download or read book Clinical Aspects of Albumin written by S.H. Yap and published by Springer. This book was released on 2011-12-14 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Albumin is the most abundant serum protein produced by the liver. In clinical practice the serum level of albumin continues to be used as an important marker of the presence, progress or ofthe improvement of many diseases, even though it is the complex end result of synthesis, degradation a. nd distribution between intra- and extravascular space. The clinical history of albumin began as early as in 1837, when Ancell first recognized "albumen" and noted that this protein is needed for trans port functions, for maintaining fluidity of the vascular system and for the prevention of edema. However, the important physiological properties of serum proteins and their role in the regulation ofthe oncotic pressure were demonstrated later by the physiologist E. H. Starling in 1895. In 1917 the clinician A. A. Epstein first described the edema in patients with the nephro tic syndrome as being a result of a very low level of serum albumin. Al though the determination of serum albumin concentration became more popular after Howe in 1921 introduced the technique of separation of serum globulins from albumin by sodium sulfate, the first preparations of human serum albumin were made available for clinical use in only 1941 by the development of plasma fractionation by Cohn and his coworkers at Harvard Medical School.
Download or read book Manual of Veterinary Transfusion Medicine and Blood Banking written by Kenichiro Yagi and published by John Wiley & Sons. This book was released on 2016-09-06 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a practical approach, the Manual of Veterinary Transfusion Medicine and Blood Banking provides veterinary practitioners with evidence-based guidelines to refer to at the clinical practice level. Provides evidence-based information on transfusion medicine and blood banking practices Presents sections on recipient screening, donor selection, blood collection and storage, and how to meet blood product demands Includes useful protocols for transfusions and blood banking relevant to clinical practice Incorporates the balanced perspectives of veterinarians and veterinary technicians Contains information pertaining to large, small, and exotic animals
Download or read book Therapy in Nephrology and Hypertension E Book written by Christopher S. Wilcox and published by Elsevier Health Sciences. This book was released on 2008-08-22 with total page 1161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised, the new edition of this companion to Brenner & Rector’s The Kidney equips you with today’s guidance to effectively manage renal and hypertension patients. International authorities emphasize the specifics of treatment while presenting field-tested advice on the best therapeutic strategies available. New chapters reflect the latest evidence impacting current clinical issues, while a new design helps you reference the information more easily. Presents the most comprehensive text available on nephrology and hypertension treatment for a convenient single source that is easy to consult. Features the evidence-based guidance of leading authorities for making more informed clinical decisions. Offers in-depth discussions and referenced coverage of key trials to help you analyze the results and the evidence provided. Provides treatment algorithms and tables of commonly used drugs in each chapter for quick-access expert advice on arriving at the best and most appropriate treatment regimen. Offers new chapters on erectile and sexual dysfunction, transplant immunology and immunosuppression, dietary salt restriction, and systematic vasculitis and pauci-immune glomerulonephritis that reflect new evidence impacting current clinical issues. Presents the contributions of newly assigned section editors—authorities in their subspecialty fields—who offer you the benefit of their practice-proven expertise. Provides rationales for the therapies presented to help you choose the most effective treatment for each patient.
Download or read book Clinical Aspects of Albumin written by S.H. Yap and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Albumin is the most abundant serum protein produced by the liver. In clinical practice the serum level of albumin continues to be used as an important marker of the presence, progress or ofthe improvement of many diseases, even though it is the complex end result of synthesis, degradation a. nd distribution between intra- and extravascular space. The clinical history of albumin began as early as in 1837, when Ancell first recognized "albumen" and noted that this protein is needed for trans port functions, for maintaining fluidity of the vascular system and for the prevention of edema. However, the important physiological properties of serum proteins and their role in the regulation ofthe oncotic pressure were demonstrated later by the physiologist E. H. Starling in 1895. In 1917 the clinician A. A. Epstein first described the edema in patients with the nephro tic syndrome as being a result of a very low level of serum albumin. Al though the determination of serum albumin concentration became more popular after Howe in 1921 introduced the technique of separation of serum globulins from albumin by sodium sulfate, the first preparations of human serum albumin were made available for clinical use in only 1941 by the development of plasma fractionation by Cohn and his coworkers at Harvard Medical School.
Download or read book Therapeutic Plasma Exchange written by H.-J. Gurland and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains papers and discussions of the Vlth Dialyse-Arzte Workshop, which was held in Bernried at Lake Starnberg near Munich the 5th and 6th of March 1980. Generous ly sponsored by Travenol, Munich, the Dialyse-Arzte meetings now have a tradition spanning 16 years. According to the con stitution of these meetings, the topics of earlier years had to cover dialysis and related fields. Thus the sponsor requested that this year also one lecture - incorporated here as part - should deal with the state of art of dialysis, thereby hopefully linking this Workshop to the previous meetings. Dialysis techniques of the 1960s, pioneered by many of attend ing speakers and panelists (see List of Contributors), have never come to a standstill. Indeed, vascular access and extra corporeal circulation have become routine for the nephrologist and have made possible the introductimn of new approaches, such as hemofiltration and hemoperfusion. Also today new membrane technologies provide us with a potentially even more effective therapeutic tool, namely plasma separation.
