Download or read book Advances in childhood leukemia written by and published by . This book was released on 1982 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Download or read book Advances in Childhood Leukemia written by and published by . This book was released on 1982 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pediatric Acute Lymphoblastic Leukemia written by Sneha Tandon and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer and accounts for approximately 75% of all cases of childhood leukemia. Both diagnostic and therapeutic advances have been instrumental in improving the outcomes of once a dreaded disease. Currently, approximately 90% of the children treated according to risk-directed and response-adapted therapy will be long-term survivors. The use of pediatric protocols for the treatment of adolescent and young adults (AYA) has also resulted in significant improvements in their long-term survival. New therapies including tyrosine kinase inhibitors (TKIs), monoclonal antibodies and CAR T-cell therapy are changing the approach to therapy for relapsed or refractory disease. We are approaching a time where therapy for all patients will be personalized with the use of genome-based characterization of disease and incorporation of drugs against actionable targets, ultimately leading to improved clinical outcomes and decreased toxicity of therapy. Still, certain subgroups including patients with relapsed disease, infant ALL, and those with certain cytogenetic/molecular variants, remain challenging to treat. This chapter is an overview of the recent advances in the ALL disease biology, newly identified prognostic factors and an overview of emerging therapeutic options.
Download or read book Pediatric Acute Lymphoblastic Leukemia written by Motohiro Kato and published by Springer Nature. This book was released on 2019-11-26 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses key aspects of childhood acute lymphoblastic leukemia (ALL), presenting the latest research on the biology and treatment of the disease and related issues. The cure rate for ALL has improved dramatically due to advances such as supportive care, treatment stratification based on relapse risk, and the optimization of treatment regimens. Gathering contributions by eminent scholars Pediatric Acute Lymphoblastic Leukemia is a valuable resource for pediatric hematologists as well as for medical students, interns, residents and fellows. It not only offers comprehensive insights, but also provides a springboard for future research.
Download or read book Progress Against Leukemia written by National Cancer Institute (U.S.) and published by . This book was released on 1976 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress Against Leukemia written by National Cancer Institute (U.S.). National Cancer Program and published by . This book was released on 1976 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Childhood Leukemias written by Ching-Hon Pui and published by Cambridge University Press. This book was released on 2012-06-21 with total page 893 pages. Available in PDF, EPUB and Kindle. Book excerpt: New insights into the molecular biology of childhood leukemias have stimulated numerous advances in diagnostic methods, strategies for risk assessment and the development of novel therapy for genetic subtypes of the diseases. Fully revised and updated, this new edition of Childhood Leukemias provides the most comprehensive, clinically-oriented and authoritative reference dedicated to these diseases. Beginning with an overview of history, cell biology, and pathology, subsequent chapters review approaches in the evaluation and management of specific leukemias, new therapeutic development and the unique pharmacodynamics and pharmacogenetics of individual patients. New chapters include epigenetics of leukemias, leukemias in patients with Down syndrome and leukemia in adolescents and young adults. The final section covers the complications associated with the disease or its treatment and supportive care during and after treatment. Authored by leading experts, this is a 'must-have' for any physician or investigator who deals with leukemias in childhood.
Download or read book Advances in Managing Childhood Leukemia audiocassette written by and published by . This book was released on 1975 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diagnostic and Therapeutic Advances in Pediatric Oncology written by David O. Walterhouse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of Diagnostic and Therapeutic Advances in Pediatric Oncology for the Cancer Treatment and Research Series is to provide an up-to-date summary of how recent advances in cancer research are being applied to the care of children with solid tumors. The interface of cancer research with clinical practice in pediatric oncology has never been more intimate than today. While researchers are identifying oncogenes and tumor suppressor genes and are studying their specific functions, clinicians are using knowledge of oncogenes and tumor suppressor genes for diagnosing cancer in children, for therapeutic decision-making purposes, and for prognostic purposes. The first three chapters in this book describe models for understanding the causes of childhood cancer that were perhaps initially identified by clinicians and that are now being studied and understood by researchers. These chapters will describe research evidence that supports roles for the involvement of normal developmental regulatory genes in childhood oncogenesis, of abnormal immune regulation in childhood oncogenesis, and of heredity in childhood oncogenesis. The next eight chapters are devoted to descriptions of the appli cation of new research developments to clinical practice with reference to the most common forms of solid tumors of childhood outside the central nervous system. The final chapter will describe late effects of childhood cancer and its therapy and the impact research is having on understanding and perhaps preventing these late effects.
Download or read book Cancer Incidence and Survival Among Children and Adolescents written by and published by . This book was released on 1999 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Walking with a Shadow written by Nanci A. Sullivan and published by Bloomsbury Publishing USA. This book was released on 2004-09-30 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Childhood cancer, particularly leukemia, is on the rise. Leukemia strikes one child in every 25,000, and most often does so between the ages of 3 and 7. Annually, more than 2,700 children are diagnosed with leukemia in the United States. Due to advances in biotechnology and medicine, survival rates for this once-deadly disease now stand at 80%. But the psychological effects of diagnosis, removal from school, treatment, and remission or cure, linger. Here nine long-term survivors of childhood leukemia share their vivid memories and give us insight into the physiological changes, psychosocial and educational difficulties that became a constant shadow in their lives. Author Nanci Sullivan provides recommendations for ways teachers, counselors and other professionals may better help young students with leukemia cope.
Download or read book Cancer written by Melvyn F. Greaves and published by . This book was released on 2001 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day, 1500 Americans die of cancer, and yet for most of us this deadly disease remains mysterious. Why is it so common? Why are there so many different causes? Why does treatment so often fail? What, ultimately, is cancer? In this fascinating new book, a leading cancer researcher offers general readers clear and convincing answers to these and many other questions. Mel Greaves places cancer in its evolutionary context, arguing that we can best answer the big questions about cancer by looking through a Darwinian lens. Drawing on both ancient and more modern evolutionary legacies, he shows how human development has changed the rules of evolutionary games, trapping us in a nature-nurture mismatch. Compelling examples, from the King of Naples intestinal tumor in the 15th century, through the epidemic of scrotal skin cancer in 18th-century chimney sweeps, to the current surge of cases of prostate cancer illustrate his thesis. He also shows why the old paradigms of infectious diseases or genetic disorders have proved fruitless when trying to explain this complex and elusive disease. And finally, he looks at the implications for research, prevention, and treatment of cancer that an evolutionary perspective provides. Drawing on the most recent research, this is the first book to put cancer in its evolutionary framework. At a time when Darwinian perspectives on everything from language acquisition to economics are providing new breakthroughs in understanding, medicine seems to have much to gain from the insights provided by evolutionary biology. Written in an exceptionally lucid and entertaining style, this book will be of broad interest to all those who wish to know more about this dread disease.
Download or read book Childhood Leukemia written by Nancy Keene and published by Childhood Cancer Guides. This book was released on 2010-02-01 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately 3,300 children are diagnosed with leukemia in the United States each year. The illness and its treatment can have a devastating effect on family, friends, schoolmates, and the larger community. This newly updated edition of Childhood Leukemia contains the information and support parents need during this difficult time. Author Nancy Keene provides parents and family members with: • Updates on treatment, including stem cell transplants, information about tailoring drugs dosages to children’s genetic profiles, and new methods for dealing with side effects. • Practical advice on how to cope with medical procedures, hospitalization, school, family, and financial issues. • Suggestion son ways to form a partnership with the medical team. • Stories from family members who have coped with leukemia and its treatments. • Updated resources for medical information, emotional support, and financial assistance. • A pull out medical record-keeper. Parents who read this book will find understandable medical infomation, obtain advice that eases their daily life, and feel empowered to be strong advocates for their child.
Download or read book EBMT HANDBOOK written by and published by . This book was released on 2025 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book White Blood written by Mel Greaves and published by World Scientific. This book was released on 2008 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are countless academic books on the subject of childhood leukemia. The idea behind this book, however, is very different. Here, we look at the extraordinary story of childhood leukemia from very distinct and unique perspectives: a distinguished physician who has lived through the transition of the disease from despair to success (and who played a key role in the latter); a distinguished laboratory scientist who has helped breach the barrenness of biological ignorance of the disease to reveal its nature; a patient who has been confronted with the tough realities of the illness and has been cured; and parents who have been given the worst possible news ? that their child is diagnosed with leukemia ? and who have endured the prolonged treatment, hope, and despair or relief that follows.These individuals recount their personal experiences, challenges, and ?interactions? with the disease in ways that complement and contrast with each other. Thus, not only does the book contain extraordinary stories involving the very best of biomedical research and clinical advances, but it also embodies very human tales of resilience, optimism and courage.
