Download or read book Advances in Brain Vascular Research written by Ana Clara Cristóvão and published by Cambridge Scholars Publishing. This book was released on 2020-07-24 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain vasculature nurtures and regulates basic functions of the central nervous system (CNS), acting as a barrier against pathogens. This book provides in-depth and focused data on the characteristics, function and role of brain blood vessels in health and disease. It addresses topics such as vascular activity, cell-cell communication, and the role of the endothelium in the development of the most prevalent types of cerebrovascular disease, neurodegenerative disorders, cognitive impairment, and vascular abnormalities. It offers an updated view of the current state of microvascular biology and research, and thus supports the discovery of new therapeutic agents and procedures directed at several CNS disorders.
Download or read book Advances in Brain Ischemia Research and Treatment 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Brain Ischemia Research and Treatment / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Brain Ischemia in a concise format. The editors have built Advances in Brain Ischemia Research and Treatment / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Brain Ischemia in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Brain Ischemia Research and Treatment / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Cerebral Arterial Diseases Advances in Research and Treatment 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cerebral Arterial Diseases in a concise format. The editors have built Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cerebral Arterial Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Advances in Brain Research written by Owen B. Williams and published by Nova Biomedical Books. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents and discusses topical data in the field of brain research. Topics discussed herein include nonpharmacological inhibition of cerebral dopaminergic activity; neuropsychology of the sense of agency; glucocorticoid-mediated regulation of tight junctions in brain vascular endothelium; the hierarchial organization and cerebral lateralisation of hand control and its relationship to language; and a unique cause of traumatic brain injury and all neuro-musculo-skeletal injuries.
Download or read book Advances in Brain Research written by Kei Satoh and published by Elsevier Science Health Science Division. This book was released on 2003 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the outcome of the 6th Hirosaki international Forum that was aimed to update the recent studies on neurological disorders of mainly elderly patients, particularly vascular and neurodegenerative disorders. Specific topics include genetic background of cerebrovascular diseases. Recent advance in the study of vascular spasm after subarachnoid hemorrhage is another major subject. In the field of neurodegenerative disorders, special emphasis was laid on the therapeutic strategy of Parkinson's disease. Pathogenesis of other degenerative diseases such as Alzheimer's disease is also a highlight of this volume.
Download or read book Cerebral Blood Flow Metabolism and Head Trauma written by Christian W. Kreipke and published by Springer Science & Business Media. This book was released on 2012-08-07 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written to satisfy a wide audience, from basic scientist to clinical researcher, this volume explores such varied concepts as: the influence of CBF in the pathotrajectory of TBI, modeling TBI as a means to understand underlying pathological states associated with brain injury victims, disrupted vasculature following head trauma and advanced imaging techniques, vasoreactive substances underlying disrupted blood flow, the role of age and sex on injury outcome, and the latest pre-clinical rationale for focusing on CBF and strategies to improve blood flow as a means to improve outcome in patients suffering the effects of TBI.
Download or read book Cerebral Vasospasm written by R. Loch Macdonald and published by Thieme. This book was released on 2011-01-01 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from the top neurovascular centers around the world, this valuable resource explores the remarkable progress made in treating cerebral vasospasm, enhanced by nearly 200 high-quality illustrations. Coverage includes: the role of potassium channels, the use of PET scanning, management with thrombolytic agents, decision analysis in treatment plans, and much more. You will also find the latest information on molecular mechanisms, remodeling and inflammation, experimental endothelium research, and the pathophysiology of vasospasm. Special features: Contributions from top international specialists Reviews all new clinical and research advances Offers authoritative coverage of pathophysiology, experimental treatments, endovascular surgery, and other important management issues Nearly 200 clear images bring material to life and highlight key concepts Straightforward text designed for easy readability and quick reference The study of cerebral vasospasm following aneurysmal subarachnoid hemorrhage has seen great strides in the past decade, leading to significant progress in diagnostic and therapeutic techniques. Offering an incisive summary of these advances, here is the book that all neurosurgeons, vascular specialists, emergency room physicians, and neuroradiologists need for a deeper understanding of this multi-faceted condition.
Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Download or read book Advances in Dementia Research written by Kurt Jellinger and published by Springer. This book was released on 2000-07-14 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dementia is a major health problem that becomes increasingly common with advancing age. Despite recent progress in neurobiology and molecular genetics, the aetiology and pathogenesis of most dementia disorders are still poorly understood, and early exact diagnosis as a prerequisite of effective treatment needs to be improved. The present volume includes the contributions of renowned experts in the field of neurodegeneration presented at the International Symposium "Ageing and Dementia 1999”, September 24–26, 1999 at Graz. It focusses on genetics, epidemiology, new neuroimaging techniques, and the role of vascular, immunological and other mechanisms including oxidative stress and estrogens in the development of neurodegeneration and dementia. Recent developments in diagnosis and therapy of Alzheimer disease and related disorders are reviewed and future therapeutic approaches are discussed. Thus, this volume provides a timely overview of most recent developments in dementia research and treatment strategies of dementia disorders.
Download or read book Cerebral Small Vessel Disease written by Leonardo Pantoni and published by Cambridge University Press. This book was released on 2014-05 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
Download or read book Clinical Bioinformatics written by Ronald Trent and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Clinical Bioinformatics, Second Edition, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in omics, such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Clinical Bioinformatics, Second Edition serves as an ideal guide for scientists and health professionals working in genetics and genomics.
Download or read book Alzheimer s Turning Point written by Jack C. de la Torre and published by Springer. This book was released on 2016-06-25 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Download or read book New Developments in Dementia Prevention Research written by Kate Irving and published by Routledge. This book was released on 2018-11-02 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Developments in Dementia Prevention Research addresses a dearth of knowledge about dementia prevention and shows the importance of considering the broader social impact of certain risk factors, including the role we each play in our own cognitive health throughout the lifespan. The book draws on primary and secondary research in order to investigate the relationship between modifiable factors, including vascular and psychosocial risks, that may affect the incidence of dementia. Bringing together world-leading expertise from applied science, medicine, psychology, health promotion, epidemiology, health economics, social policy and primary care, the book compares and contrasts scientific and service developments across a range of settings. Each chapter presents these themes in a way that will ensure best practice and further research in the field of dementia prevention is disseminated successfully throughout the world. Perhaps most importantly, chapters also question what type of social responsibility we are prepared to embrace in order to address the challenges inherent in dementia prevalence. New Developments in Dementia Prevention Research includes contributions from leading authorities in brain health and dementia prevention and provides an essential contribution to the discourse on dementia prevention. It will be of great interest to academics, researchers and postgraduate students engaged in the study of the psychological and social aspects of aging and dementia.
Download or read book Atlas of Normal Imaging Variations of the Brain Skull and Craniocervical Vasculature written by Alexander M. McKinney and published by Springer. This book was released on 2017-01-09 with total page 1320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas presents normal imaging variations of the brain, skull, and craniocervical vasculature. Magnetic resonance (MR) imaging and computed tomography (CT) have advanced dramatically in the past 10 years, particularly in regard to new techniques and 3D imaging. One of the major problems experienced by radiologists and clinicians is the interpretation of normal variants as compared with the abnormalities that the variants mimic. Through an extensive collection of images, this book offers a spectrum of appearances for each variant with accompanying 3D imaging for confirmation; explores common artifacts on MR and CT that simulate disease; discusses each variant in terms of the relevant anatomy; and presents comparison cases for the purpose of distinguishing normal findings from abnormalities. It includes both common variants as well as newly identified variants that are visualized by recently developed techniques such as diffusion-weighted imaging and multidetector/multislice CT. The book also highlights normal imaging variants in pediatric cases. Atlas of Normal Imaging Variations of the Brain, Skull, and Craniocervical Vasculature is a valuable resource for neuroradiologists, neurologists, neurosurgeons, and radiologists in interpreting the most common and identifiable variants and using the best methods to classify them expediently.
Download or read book Vascular Development written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2007-08-20 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.
Download or read book Introduction to Vascular Neurosurgery written by Justin R. Mascitelli and published by Springer Nature. This book was released on 2022-01-12 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to cover the majority of neurovascular diseases and management. The first section reviews neurovascular anatomy, the basics of angiography, and the basics of craniotomies for neurovascular diseases. Next, an entire section is devoted to intracranial aneurysms, covering the natural history, subarachnoid hemorrhage, endovascular management, microsurgical management, and vasospasm. Following this, a number of chapters are devoted to stroke including natural history, mechanical thrombectomy, intracranial stenosis, Moyamoya disease, bypass surgery, vertebrobasilar insufficiency, intracerebral hemorrhage, sinus thrombosis, and the surgical and endovascular management of extracranial carotid disease. Next, the text covers vascular malformations including arteriovenous malformation, arteriovenous fistulas, carotid cavernous fistulas, vein of Galen malformations, spinal malformations, and cavernous malformations. Finally, the book discusses a few miscellaneous topics including more recent advances in neurovascular care such as venous sinus stenting for idiopathic intracranial hypertension and middle meningeal artery embolization for subdural hematoma. Written by experts in the field, Introduction to Vascular Neurosurgery provides a comprehensive summary of neurovascular disease and management. The book can be used as a daily reference and serves as a trusted resource for medical students, residents, fellows, and young attendings.
