Download or read book Adjoint Methods for External Beam Inverse Treatment Planning written by Michael E. Kowalok and published by . This book was released on 2004 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Adjoint Method for The Optimization of Brachytherapy and Radiotherapy Patient Treatment Planning Procedures Using Monte Carlo Calculations written by and published by . This book was released on 2001 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this project is to investigate the use of the adjoint method, commonly used in the reactor physics community, for the optimization of radiation therapy patient treatment plans. Two different types of radiation therapy are being examined, interstitial brachytherapy and radiotherapy. In brachytherapy radioactive sources are surgically implanted within the diseased organ such as the prostate to treat the cancerous tissue. With radiotherapy, the x-ray source is usually located at a distance of about 1-metere from the patient and focused on the treatment area. For brachytherapy the optimization phase of the treatment plan consists of determining the optimal placement of the radioactive sources, which delivers the prescribed dose to the disease tissue while simultaneously sparing (reducing) the dose to sensitive tissue and organs. For external beam radiation therapy the optimization phase of the treatment plan consists of determining the optimal direction and intensity of beam, which provides complete coverage of the tumor region with the prescribed dose while simultaneously avoiding sensitive tissue areas. For both therapy methods, the optimal treatment plan is one in which the diseased tissue has been treated with the prescribed dose and dose to the sensitive tissue and organs has been kept to a minimum.
Download or read book Adjoint Based Treatment Planning for Brachytherapy written by Vibha Chaswal and published by . This book was released on 2008 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Beamlet based Treatment Plan Optimization in External Beam Radiation Therapy written by Ho Jin Kim and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: External beam radiation therapy is one of the most widely used therapeutic methods for treating patients. In this modality, prior to the actual treatment, machine delivery parameters are optimized based on a patient model derived from the pre-treatment CT images. The goal of treatment planning is to maximize the dose to the planning target volume (PTV), while sparing the critical organs. A number of treatment techniques have been developed to meet the clinical demands. In reality, however, these techniques suffer from a series of problems and the performance of currently available plan optimization and dose delivery techniques is sub-optimal - the treatment plans out of the optimization algorithms are often not clinically sensible. Hence, considerable effort may be required to plan a patient's treatment, seriously hindering the optimal and efficient use of the radiation therapy. This thesis presents efficient and effective fluence-map optimizing techniques to demonstrate the improvement in either plan quality or delivery efficiency in static field and (continuous) rotational arc treatment schemes. To attain the objective above, new mathematical models and beam configurations are employed in the center of the treatment planning and its optimizing process. Of note, the demonstrations of our proposed methods or strategies proceed in two directions: (1) improving the delivery efficiency without damaging the plan quality, and (2) enhancing the plan quality, while maintaining the similar delivery efficiency of the existing methods.
Download or read book Efficient Optimization Techniques for IMRT Treatment Planning written by Arinbjörn Ólafsson and published by . This book was released on 2006 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optimization of Brachytherapy Treatment Planning Using Adjoint Functions written by Sua Yoo and published by . This book was released on 2003 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optimization Approaches for Planning External Beam Radiotherapy written by Halil Ozan Gozbasi and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: External beam radiotherapy is delivered from outside the body aimed at cancer cells to damage their DNA making them unable to divide and reproduce. The beams travel through the body and may damage nearby healthy tissues unless carefullyplanned. Therefore, the goal of treatment plan optimization is to find the best system configuration to deliver sufficient dose to target structures while avoiding damage to healthy tissues. This thesis investigates optimization approaches for two external beam radiation therapy techniques: Intensity-Modulated Radiation Therapy (IMRT) and Volumetric-Modulated Arc Therapy (VMAT). We develop an automated treatment planning technology for IMRT which generates several high-quality treatment plans satisfying the provided requirements in a single invocation and without human guidance. Our approach is based on an existing linear programming-based fluence map optimization model that approximates dose-volume requirements using conditional value-at-risk (C-VaR) constraints. We show how the parameters of the C-VaR constraints can be used to control various metrics of treatment plan quality. A novel bi-criteria scoring based beam selection algorithm is developed which finds the best beam configuration at least ten times faster for real-life brain, prostate, and head and neck cases as compared to an exact mixed integer programming model. Patient anatomy changes due to breathing during the treatment of lung cancer need to be considered in treatment planning. To date, a single phase of the breathing cycle is typically selected for treatment and radiation is shut-off in other phases. We investigate optimization technology that finds optimal fluence maps for each phase of the breathing cycle by considering the overall dose delivered to a patient using image registration algorithms to track target structures and organs at risk. Because the optimization exploits the opportunities provided in each phase, better treatment plans are obtained. The improvements are shown on a real-life lung case. VMAT is a recent radiation treatment technology which has the potential to provide treatments in less time compared to other delivery techniques. This enhances patient comfort and allows for the treatment of more patients. We build a large-scale mixed-integer programming model for VMAT treatment plan optimization. The solution of this model is computationally prohibitive. Therefore, we develop an iterative MIP-based heuristic algorithm which solves the model multiple times on a reduced set of decision variables. We introduce valid inequalities that decrease solution times, and, more importantly, that identify higher quality integer solutions within specified time limits. Computational studies on a spinal tumor and a prostate tumor case produce clinically acceptable results.
Download or read book External Beam Therapy written by Peter Hoskin and published by Oxford University Press (UK). This book was released on 2012-08-30 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: External Beam Therapy is used to aim highly focused beams of radiation at the edge of the site where cancer is found. This second editon provides practical guidance of the use of External Beam Therapy, taking the reader through the basic principles covering indications, treatment, and then developing this by individual sites.
Download or read book Optimization of External Radiation Beams for Therapy Planning written by Tom Lewis Gallagher and published by . This book was released on 1967 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book On the Use of Cimmino s Simultaneous Projections Method for Computing a Solution of the Inverse Problem in Radiation Therapy Treatment Planning written by Yair Censor and published by . This book was released on 1987 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Beam Orientation Optimization in Intensity modulated Radiation Therapy Treatment Planning written by Andrei Pugachev and published by . This book was released on 2002 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Methods for Solving the Inverse Problem in Radiation Therapy Planning written by Jochen Höffner and published by . This book was released on 1997 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Comparison Study on Beam Angle Optimization Methods in Radiation Treatment Planning written by Abhilasha A. Kelkar and published by . This book was released on 2011 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Treatment Planning for External Beam Therapy with Neutrons written by Georg Burger and published by Williams & Wilkins. This book was released on 1981 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Treatment Planning in Adaptive Radiotherapy written by Chuan Wu and published by . This book was released on 2002 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development and Application of a Multi modality Inverse Treatment Planning System written by and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of intensity-modulated radiation therapy (IMRT) opened new possibilities for the treatment planning process. Most of the existing treatment planning (TP) tools for the IMRT are focusing on the use of photons for the treatment. To achieve a very high computional speed only simplified dose calculation algorithms are used. Furthermore, approximations are made during the calculation of the fluence matrix. This thesis develops an IMRT planning tool which can be used with any available radiation modality and makes use of improved dose calculation algorithms. For the dose calculation engine a method was developed where the dose deposited in every voxel by all beams is precalculated and for later use stored in a dose matrix. This enables the use of advanced dose calculation algorithms and the simultaneous optimization of different radiation modalities. The new TP system was applied to clinical patient data for proton and photon IMRT plans. For the delivery of the proton IMRT plans two promising delivery techniques, 'distal edge tracking' (DET) and the 3D technique, were compared with each other. By using the DET technique dose distributions as good as for the 3D technique were achieved but the optimization time and the expected delivery time are reduced by a factor 10. In addition, no significant differences in the effect of organ motion and particle range uncertainties are observed for either technique.
Download or read book Novel Methods for Treatment Planning in Ion Beam Therapy written by Gonzalo Alfonso Cabal Arango and published by . This book was released on 2012 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:
