Download or read book Studies on the Mechanisms of Activation and Deactivation of Soluble Guanylyl Cyclase from Bovine Lung written by Elizabeth Ann Dierks and published by . This book was released on 1995 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Activation and Deactivation of Soluble Guanylate Cyclase written by Jonathan Alvin Winger and published by . This book was released on 2004 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Activation and Inhibition of Soluble Guanylyl Cyclase written by Heather S. Carr and published by . This book was released on 2000 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Investigating the Heme Environment and Mechanism of Activation of Soluble Guanylate Cyclase written by Emily Rose Derbyshire and published by . This book was released on 2008 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Role of Conformational Changes in Soluble Guanylate Cyclase Activation Mechanism written by Jasmin Kristianto and published by . This book was released on 2009 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmacological Activation of Soluble Guanylate Cyclase for Treatment of Experimental Pulmonary Hypertension written by Rio Dumitrascu and published by . This book was released on 2006 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tonic and Acute Nitric Oxide Signaling Through Soluble Guanylate Cyclase written by Stephen Patrick Lewis Cary and published by . This book was released on 2005 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Analysis of Soluble Guanylyl Cyclase Activation Using a Fluorescent Probe written by Mateja Lumpert (farmacevtka.) and published by . This book was released on 2012 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies on the Mechanisms of Activation of No sensing Soluble Guanylyl Cyclase from Bovine Lung and Co sensing CooA from Rhodospirillum Rubrum written by Mark Fredric Reynolds and published by . This book was released on 1998 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book cGMP Generators Effectors and Therapeutic Implications written by Harald H. H. W. Schmidt and published by Springer Science & Business Media. This book was released on 2008-12-17 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.
Download or read book Guanylate Cyclase written by Rameshwar K. Sharma and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: From somewhat enigmatic beginnings 40 years ago, guanylate cyclase research has emerged to occupy a position of prominence in the study of signal transduction. Guanylate cyclase has several intriguing features, including existence in two major forms, membrane and soluble, each independently regulated by distinct mechanisms. The membrane form gives rise to a fascinating signal transduction story important to both peptide hormones and sensory neurons. This volume covers the evolution of the field, peptide hormone receptor work, membrane guanylate cycles, related retinal diseases, and the biochemistry and physiology of the soluble form. The 16 chapters are written by leaders in the field.
Download or read book Carbon Monoxide in Drug Discovery written by Leo E. Otterbein and published by John Wiley & Sons. This book was released on 2022-05-10 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: CARBON MONOXIDE IN DRUG DISCOVERY An insightful reference for the latest physiological and therapeutic studies of carbon monoxide In Carbon Monoxide in Drug Discovery: Basics, Pharmacology, and Therapeutic Potential, a team of distinguished authors delivers foundational knowledge, the latest research, and remaining challenges regarding the physiological roles and therapeutic efficacy of carbon monoxide (CO). The editors have included a broad selection of resources from leading experts in the field that discuss the background and physiological roles of CO, a variety of delivery forms including CO prodrugs using benign carriers, CO sensing, therapeutic applications, and clinical trials. Organized by topic to allow each chapter to be read individually, the book covers a wide range of topics, from physiological and patho-physiological mechanisms at the molecular level to clinical applications for multiple disease processes. The editors of Carbon Monoxide in Drug Discovery have created a compelling argument for shifting the accepted understanding of CO from poison to bioactive molecule with enormous clinical benefits. Readers will also benefit from: A thorough introduction to the background and physiological actions of carbon monoxide, including endogenous CO production in sickness and in health Comprehensive explorations of CO delivery forms, including non-carrier formulations, metal-carbonyl complexes, and organic CO donors Practical discussions of carbon monoxide sensing and scavenging, including fluorescent probes for intracellular carbon monoxide detection In-depth examinations of the therapeutic applications of CO, including CO in solid organ transplantation Perfect for professors, graduate students, and postdocs in the fields of biology, pharmacology, immunology, medicinal chemistry, toxicology, and drug delivery, Carbon Monoxide in Drug Discovery: Basics, Pharmacology, and Therapeutic Potential is also an invaluable resource for industrial scientists in these areas.
Download or read book Signal Transduction Pathways Mechanisms and Diseases written by Ari Sitaramayya and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Download or read book Pharmacotherapy of Pulmonary Hypertension written by Marc Humbert and published by Springer. This book was released on 2013-10-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle section provides an overview of the established therapies, such as calcium channel blockers, prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors and inhaled nitric oxide. The last section explores novel pathways and emerging therapeutic approaches including soluble guanylate cyclase stimulators, Rho-kinase inhibitors, inhibitors of serotonin receptors and transporters, peptide growth factors, vasoactive peptides, modulators of redox equilibrium and cyclic nucleotide homeostasis, as well as immunosuppressive and anti-proliferative agents. Particular attention is given to the clinical applications of these experimental therapies, that are on the horizon. The book thus spans the continuum from basic science to clinical applications.
Download or read book Free Radicals and Inhalation Pathology written by Erich Schiller and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: An encyclopedic summary of the highlights in the field of free radicals in medicine and biology, with a detailed analysis of the extensive recent literature. The text describes results from experimental research work on dust inhalation, hypoxia, and environmental toxicology that uses morphologic methods such as electron microscopy, interference microscopy and time-lapse technqiues in tissue cultures. The volume discusses free radical reactions that are probably involved in the pathogenesis of both physical and chemical environmental hazards. It lists radical scavengers that function as useful prophylactic agents in case of unavoidable exposure. A short history of dust diseases that have challenged mankind since prehistoric times serves as an introduction to this comprehensive treatise. It is hoped that by covering this field in one monograph, the increasingly recognized and important role of both oxygen- and nitrogen-centred radicals in disease pathogenesis will become clearer. The enclosed CD includes nearly 25.000 literature citations useful as a reference source for researchers, clinicians and students.
Download or read book Phosphorus Oxygen Lyases Advances in Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phosphorus-Oxygen Lyases—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Phosphorus-Oxygen Lyases. The editors have built Phosphorus-Oxygen Lyases—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Phosphorus-Oxygen Lyases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Phosphorus-Oxygen Lyases—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Phosphorus Oxygen Lyases Advances in Research and Application 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phosphorus-Oxygen Lyases—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Adenylate Cyclase in a concise format. The editors have built Phosphorus-Oxygen Lyases—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Adenylate Cyclase in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Phosphorus-Oxygen Lyases—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
