Download or read book A Summary of General Assessment Factors for Evaluating the Quality of Scientific and Technical Information written by United States. Science Policy Council. Assessment Factors Workgroup and published by . This book was released on 2003 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines for carcinogen risk assessment written by and published by DIANE Publishing. This book was released on 2005 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
Download or read book OECD Series on Testing and Assessment Guiding Principles and Key Elements for Establishing a Weight of Evidence for Chemical Assessment written by OECD and published by OECD Publishing. This book was released on 2019-10-22 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document is intended to provide universal Guiding Principles that should be considered when developing or augmenting systematic approaches to Weight of Evidence (WoE) for chemical evaluation and Key Elements to formulating a systematic approach to WoE. The ultimate goal is to facilitate that regulators follow a consistent, clear and transparent delivery of evidence using the Principles and Elements described in this document. This can be especially helpful for countries with no existing WoE frameworks or those looking to augment their approaches. It also allows for stakeholders to understand a WoE decision-making process, including potential for unreasonable bias. These Guiding Principles and Key Elements can be employed to develop frameworks that range from simple and pragmatic approaches to more elaborate systems, depending on the context.
Download or read book Science Under Siege written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations and published by . This book was released on 2010 with total page 994 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book EPA s IRIS Program written by United States. Congress. House. Committee on Science, Space, and Technology (2011). Subcommittee on Investigations and Oversight and published by . This book was released on 2011 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Office of the science advisor staff paper risk assessment principles practices written by and published by DIANE Publishing. This book was released on 2004 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hamilton and Hardy s Industrial Toxicology written by Raymond D. Harbison and published by John Wiley & Sons. This book was released on 2015-03-16 with total page 1368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a concise, yet comprehensive, reference on all aspectsof industrial exposures and toxicants; this book aidstoxicologists, industrial hygienists, and occupational physiciansto investigate workplace health problems. • Updates and expands coverage with new chapterscovering regulatory toxicology, toxicity testing, physical hazards,high production volume (HPV) chemicals, and workplace druguse • Includes information on occupational and environmentalsources of exposure, mammalian toxicology, industrial hygiene,medical management and ecotoxicology • Retains a succinct chapter format that has become thehallmark for the previous editions • Distils a vast amount of information into one resourcefor both academics and professionals
Download or read book An Examination of EPA Risk Assessment Principles and Practices written by United States. Environmental Protection Agency. Risk Assessment Task Force and published by . This book was released on 2004 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Review of EPA s Integrated Risk Information System IRIS Process written by National Research Council and published by National Academies Press. This book was released on 2014-06-25 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Integrated Risk Information System (IRIS) is a program within the US Environmental Protection Agency (EPA) that is responsible for developing toxicologic assessments of environmental contaminants. An IRIS assessment contains hazard identifications and dose-response assessments of various chemicals related to cancer and noncancer outcomes. Although the program was created to increase consistency among toxicologic assessments within the agency, federal, state, and international agencies and other organizations have come to rely on IRIS assessments for setting regulatory standards, establishing exposure guidelines, and estimating risks to exposed populations. Over the last decade, the National Research Council (NRC) has been asked to review some of the more complex and challenging IRIS assessments, including those of formaldehyde, dioxin, and tetrachloroethylene. In 2011, an NRC committee released its review of the IRIS formaldehyde assessment. Like other NRC committees that had reviewed IRIS assessments, the formaldehyde committee identified deficiencies in the specific assessment and more broadly in some of EPA's general approaches and specific methods. Although the committee focused on evaluating the IRIS formaldehyde assessment, it provided suggestions for improving the IRIS process and a roadmap for its revision in case EPA decided to move forward with changes to the process. Congress directed EPA to implement the report's recommendations and then asked the National Research Council to review the changes that EPA was making (or proposing to make) in response to the recommendations. Review of EPA's Integrated Risk Information System (IRIS) Process provides an overview of some general issues associated with IRIS assessments. This report then addresses evidence identification and evaluation for IRIS assessments and discusses evidence integration for hazard evaluation and methods for calculating reference values and unit risks. The report makes recommendations and considerations for future directions. Overall, Review of EPA's Integrated Risk Information System Process finds that substantial improvements in the IRIS process have been made, and it is clear that EPA has embraced and is acting on the recommendations in the NRC formaldehyde report. The recommendations of this report should be seen as building on the progress that EPA has already made.
Download or read book Assessing Risks to Endangered and Threatened Species from Pesticides written by National Research Council and published by National Academies Press. This book was released on 2013-06-20 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The US Fish and Wildlife Service (FWS) and the National Marine Fisheries Service (NMFS) are responsible for protecting species that are listed as endangered or threatened under the Endangered Species Act (ESA) and for protecting habitats that are critical for their survival. The US Environmental Protection Agency (EPA) is responsible for registering or reregistering pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and must ensure that pesticide use does not cause any unreasonable adverse effects on the environment, which is interpreted to include listed species and their critical habitats. The agencies have developed their own approaches to evaluating environmental risk, and their approaches differ because their legal mandates, responsibilities, institutional cultures, and expertise differ. Over the years, the agencies have tried to resolve their differences but have been unsuccessful in reaching a consensus regarding their assessment approaches. As a result, FWS, NMFS, EPA, and the US Department of Agriculture asked the National Research Council (NRC) to examine scientific and technical issues related to determining risks posed to listed species by pesticides. Specifically, the NRC was asked to evaluate methods for identifying the best scientific data available; to evaluate approaches for developing modeling assumptions; to identify authoritative geospatial information that might be used in risk assessments; to review approaches for characterizing sublethal, indirect, and cumulative effects; to assess the scientific information available for estimating effects of mixtures and inert ingredients; and to consider the use of uncertainty factors to account for gaps in data. Assessing Risks to Endangered and Threatened Species from Pesticides, which was prepared by the NRC Committee on Ecological Risk Assessment under FIFRA and ESA, is the response to that request.
Download or read book Environmental Forensics written by Gwen O'Sullivan and published by Royal Society of Chemistry. This book was released on 2015-07-15 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is based on peer-reviewed manuscripts from the 2014 International Network of Environmental Forensics (INEF) Conference held at St John's College, Cambridge. INEF is an organization founded by environmental forensic scientists for the express purpose of sharing and disseminating environmental forensic information to the international scientific community. Providing a wide range of up to date topics on the advancement and refinement of environmental forensic techniques, this book ensures the reader gets a good understanding of the scope of environmental forensics. Aimed at scientists, regulators, academics and consultants throughout the world, this professionally edited book is the fourth of a series of INEF conference publications chronicling the current state of the art in environmental forensics. Priced at £125.00 US$200.00 €156.25
Download or read book A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment written by Natàlia Garcia-Reyero and published by Springer. This book was released on 2018-02-24 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening. This book focuses on The Adverse Outcome Pathway, an analytical construct that describes a sequential chain of causally linked events at different levels of biological organization that lead to an adverse health or ecotoxicological effect. While past efforts have focused on toxicological pathway-based vision for human and ecological health assessment relying on in vitro systems and predictive models, The Adverse Outcome Pathway framework provides a simplified and structured way to organize toxicological information. Within the book, a systems biology approach supplies the tools to infer, link, and quantify the molecular initiating events and the key events and key event relationships leading to adverse outcomes. The advancement of these tools is crucial for the successful implementation of AOPs for regulatory purposes.
Download or read book Risk Language and Power written by Jeffery T. Morris and published by Lexington Books. This book was released on 2012-02-09 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk, Language, and Power explores discourse around the environmental risks of nanotechnology, making the case that the dominance in risk discourse of regulatory science is a limiting policy debate on environmental risks, and that specific initiatives should be undertaken to broaden debate not just on nanotechnology, but generally on the risks of new technologies. Morris argues that the treatment of environmental risk in public policy debates has failed for industrial chemicals, is failing for nanotechnology, and most certainly will fail for synthetic biology and other new technologies unless we change how we describe the impacts to people and other living things from the development and deployment of technology. However, Morris also contends that the nanotechnology case provides reason for optimism that risk can be given different, and better, treatment in environmental policy debates. Risk, Language, and Power proposes specific policy initiatives to advance a richer discourse around the environmental implications of emerging technologies. Morris believes that evidence of enriched environmental policy debates would be a decentering of language concerning risk by developing within discourse language and practice directed toward enriching the human and environmental condition.
Download or read book Human and Ecological Risk Assessment written by Dennis J. Paustenbach and published by John Wiley & Sons. This book was released on 2024-04-15 with total page 1319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.
Download or read book Expert Evidence Report written by and published by . This book was released on 2003 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Extrapolation Practice for Ecotoxicological Effect Characterization of Chemicals written by Keith R. Solomon and published by CRC Press. This book was released on 2008-05-23 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: A wide-ranging compilation of techniques, Extrapolation Practice for Ecotoxicological Effect Characterization of Chemicals describes methods of extrapolation in the framework of ecological risk assessment. The book, informally known as EXPECT, identifies data needs and situations where these extrapolations can be most usefully applied, makin
