Download or read book A Study In Vitro of Cell Mediated Immunity to Listeria Monocytogenes written by Tobi Lynn Jones and published by . This book was released on 1972 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies on Cell mediated Immunity to Listeria Monocytogenes in Guinea Pigs and Modulation of Tumor Growth with Listeria written by Meher Manek Dustoor and published by . This book was released on 1976 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterization of the Cell mediated Immune Response to Listeria Monocytogenes in the Murine BALB c Model written by Cleo Dean Gilliland and published by . This book was released on 1978 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book In Vivo and in Vitro Studies of Cell mediated Reactions to Listeria Monocytogenes written by Cornelis van der Meer and published by . This book was released on 1980 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Immunity to Listeria Monocytogenes written by and published by . This book was released on 1997 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Immunity to Listeria Monocytogenes written by and published by Academic Press. This book was released on 2012-01-25 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. Contributions from leading authorities Informs and updates on all the latest developments in the field

Download or read book Recombinant Listeria Monocytogenes as a Live Vaccine Vector and a Probe for Studying Cell mediated Immunity written by Eric Raymond Jensen and published by . This book was released on 1998 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Listeria monocytogenes Pathogenesis and Host Response written by Howard Goldfine and published by Springer Science & Business Media. This book was released on 2007-06-24 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past twenty years Listeria monocytogenes has emerged as one of the most intensely studied bacterial pathogens. New windows are constantly being opened into the complexity of host cell biology and the interplay of the signals connecting the various cells and organs involved in the host response. This volume includes research from studies at the molecular level on the pathogenesis of Listeria monocytogenes and the response of the host to its infections.

Download or read book Role of Eicosanoids on Cell mediated Immunity to Listeria Monocytogenes and Its Implications on Cancer Therapy written by Courtney Elizabeth McDougal and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: [Listeria monocytogenes] is an intracellular bacterium that elicits a robust CD8[+] T-cell response. Due to thisrobust response, it is both used as a model to understand how T-cell responses are primed, as well a cancer immunotherapeutic platform. Despite decades of research, intricacies as to how [L. monocytogenes] primes T-cell responses remains incompletely understood. We and others hypothesized that cytosolic innate pathways would be critical for generating immunity, as strains of [L. monocytogenes] that cannot access the cytosol fail to induce productive T-cell responses. Counterintuitively, however, activation of known cytosolic pathways such as type I IFN and inflammasomes lead to impaired responses. In this thesis, I identify the first known cytosolic innate pathway that is critical for generating immunity to [L. monocytogenes]. I show that production of lipid mediators of inflammation called eicosanoids, namely prostaglandin E[2] (PGE[2]) produced downstream of cyclooxygenase-2 (COX-2), are critical for immunity. Immunization of mice deficient in PGE[2] have impaired CD8[+] T-cell responses. Importantly, cytosolic access is critical to induce this pathway. In vivo, infection with wild-type [L. monocytogenes] elicits a 10- fold increase in PGE[2] production whereas vacuole-constrained strains fail to induce PGE[2] over mock-immunized controls. Furthermore, I identify that macrophages and dendritic cells specifically produce PGE[2] during cytosolic infection. Finally, I show that PGE[2] signals on two different receptors during [L. monocytogenes] infection, EP3 and EP4. EP3 signaling is critical for [L. monocytogenes]-stimulated immunity, whereas EP4 signaling impairs immunity. Taken together, my work identifies the first known cytosolic pathway critical for immunity to [L. monocytogenes], and suggests a model by which cytosolically-infected macrophages and dendritic cells produce PGE2 which subsequently signals through the EP3 and EP4 receptors.

Download or read book Foodborne Microbial Pathogens written by Arun K. Bhunia and published by Springer. This book was released on 2018-05-21 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book primarily covers the general description of foodborne pathogens and their mechanisms of pathogenesis, control and prevention, and detection strategies, with easy-to-comprehend illustrations. The book is an essential resource for food microbiology graduate or undergraduate students, microbiology professionals, and academicians involved in food microbiology, food safety, and food defense-related research or teaching. This new edition covers the significant progress that has been made since 2008 in understanding the pathogenic mechanism of some common foodborne pathogens, and the host-pathogen interaction. Foodborne and food-associated zoonotic pathogens, responsible for high rates of mortality and morbidity, are discussed in detail. Chapters on foodborne viruses, parasites, molds and mycotoxins, and fish and shellfish are expanded. Additionally, chapters on opportunistic and emerging foodborne pathogens including Nipah virus, Ebola virus, Aeromonas hydrophila, Brucella abortus, Clostridium difficile, Cronobacter sakazakii, and Plesiomonas shigelloides have been added. The second edition contains more line drawings, color photographs, and hand-drawn illustrations.

Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Download or read book The New Microbiology written by Pascale Cossart and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiology has undergone radical changes over the past few decades, ushering in an exciting new era in science. In The New Microbiology, Pascale Cossart tells a splendid story about the revolution in microbiology, especially in bacteriology. This story has wide-ranging implications for human health and medicine, agriculture, environmental science, and our understanding of evolution. The revolution results from the powerful tools of molecular and cellular biology, genomics, and bioinformatics, which have yielded amazing discoveries, from entire genome sequences to video of bacteria invading host cells. This book is for both scientists and especially nonscientists who would like to learn more about the extraordinary world of bacteria. Dr. Cossart's overview of the field of microbiology research, from infectious disease history to the ongoing scientific revolution resulting from CRISPR technologies, is presented in four parts. New concepts in microbiology introduces the world of bacteria and some recent discoveries about how they live, such as the role of regulatory RNAs including riboswitches, the CRISPR defense system, and resistance to antibiotics. Sociomicrobiology: the social lives of bacteria helps us see the new paradigm by which scientists view bacteria as highly social creatures that communicate in many ways, for example in the assemblies that reside in our intestine or in the environment. The biology of infections reviews some of history's worst epidemics and describes current and emerging infectious diseases, the organisms that cause them, and how they produce an infection. Bacteria as tools introduces us to molecules derived from microbes that scientists have harnessed in the service of research and medicine, including the CRISPR/Cas9 genome-editing technology. The New Microbiology takes us on a journey through a remarkable revolution in science that is occurring here and now.

Download or read book Immunobiology of the Macrophage written by David S. Nelson and published by Academic Press. This book was released on 2014-06-28 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunobiology of the Macrophage presents an account of the state of knowledge of the immunobiology of the macrophage. The book’s contributors—immunologists of diverse scientific and geographic backgrounds—have been encouraged to give personal accounts of developments in their special fields of interest as well as critical surveys of the backgrounds leading to these developments. The book begins with a study on the functions of macrophages in the initiation and regulation of antibody responses in vitro. This is followed by separate chapters on topics such as the role of macrophages in making antigen more immunogenic and less tolerogenic; functional distinctions between macrophages at different sites; and the role of the macrophage in antigen recognition by T lymphocytes. Subsequent chapters examine interactions between macrophages and lymphocytes in the production of interferon and other mediators of cellular immunity; macrophage cell lines and their uses in immunobiology; and cytotoxic macrophages in allograft rejection.

Download or read book The Inflammasomes written by Isabelle Couillin and published by Springer Science & Business Media. This book was released on 2011-07-02 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.

Download or read book Further Studies in the Assessment of Toxic Actions written by P. L. Chambers and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book CRISPR Cas Systems written by Rodolphe Barrangou and published by Springer Science & Business Media. This book was released on 2012-12-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1993 with total page 1488 pages. Available in PDF, EPUB and Kindle. Book excerpt: