Download or read book A New Cyclohexyl based Chiral Auxiliary written by Ali Mohsen Al Hazmi and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A New Cyclohexyl based Chiral Auxiliary written by Ali Al-Hazmi and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Effectiveness of a New Cyclohexyl Chiral Auxiliary and Studies Towards the Systhesis of Bicyclo 4 4 4 tetradeca 3 8 12 triyne written by Hamish Saul Christie and published by . This book was released on 1999 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Key Chiral Auxiliary Applications written by Gregory Roos and published by Academic Press. This book was released on 2014-01-20 with total page 1271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications (2001), as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of results. This anticipated edition is based on a screening of nearly 40,000 auxiliary reaction applications, with details supplied for the more than 13,000 selected representative entries: synthetic route, reagents, yields, diastereomeric/enantiomeric excesses, and characterization data. Updated and streamlined with more than 60% new material, Key Chiral Auxiliary Applications provides valuable guidance and reliable content for selecting the best auxiliary for a specific asymmetric synthetic transformation. Provides a comprehensive compilation based on nearly 40,000 diverse applications of chiral auxiliaries for selecting the best synthetic route to optically pure compounds Contains over 60% new material with 13,000+ auxiliary applications categorized by reaction type, with reaction details and chemical and optical yields in one unique resource

Download or read book Chiral Auxiliaries and Ligands in Asymmetric Synthesis written by J. Seyden-Penne and published by Wiley-Interscience. This book was released on 1995-10-23 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table of Contents Preface Abbreviations Introduction 1 1 Enantiomerically Pure Chiral Auxiliaries 43 2 Chiral Reagents 87 3 Chiral Catalysis and Catalysts Bearing Chiral Ligands 117 4 Asymmetric Deprotonations and Protonations 143 5 Alkylations and Related Reactions 157 6 Additions to C=O and C=N Double Bonds 209 7 Additions to Carbon-Carbon Double Bonds 367 8 Additions to Double Bonds Bearing Heteroatoms. Oxidations of Sulfides and Selenides 503 9 Cycloadditions 513 10 Sigmatropic Rearrangements 593 11 Transition Metal Catalyzed Reactions 619 References 637 Index 707.

Download or read book A New Chiral Auxiliary for Asymmetric Synthesis written by Trystan Ross Nicholls and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chiral Building Blocks in Asymmetric Synthesis written by Jacek Wojaczynski and published by John Wiley & Sons. This book was released on 2022-08-05 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. In Chiral Building Blocks in Asymmetric Synthesis readers will also find: Organization according to the most important compound classes — e.g. amino acids, BINOL and its derivatives, terpenes, and others — with an emphasis on synthesis and application A focus on the use of chiral building blocks for the preparation of bioactive compounds and supramolecular assemblies Chiral Building Blocks in Asymmetric Synthesis is a useful reference for organic chemists, catalytic chemists, chemists in industry, medicinal chemists, pharmaceutical chemists, and the libraries that support them.

Download or read book Compendium of Chiral Auxiliary Applications Three Volume Set written by Gregory Roos and published by Academic Press. This book was released on 2002-01-04 with total page 1423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Compendium is a detailed compilation of chiral auxiliaries which are used in the field of organic chemistry to direct "asymmetric synthesis". A molecule is called chiral because it can have two "enantiomers" -- like left and right-handed molecules. An enantiomer is either of two molecules of the same chemical composition that are mirror images of each other but not identical. A "chiral auxiliary" is an aid / auxiliary used to specifically produce either the left or right enantiomer of the chosen molecule, as desired. In this comprehesive reference source, industrial chemists can make informed selections of an auxiliary for a specific application. It is fully cross-referenced to enable the comparative selection of auxiliaries. The work includes over 13,000 auxiliary reaction applications with complete reaction details of the synthetic routes, reagents, and primary literature references. Key Features * This remarkable major reference work is the first such compilation and represents the only total source for the diverse applications of auxiliaries * Thoroughly cross-referenced to enable comparative

Download or read book New Silicon based Chiral Auxiliaries written by Sandra Gassmann and published by . This book was released on 2000 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Development and Applications of a New Chiral Auxiliary written by Keith James Grant and published by . This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract; An endo-borneol based oxazolidinone was used in a series of asymmetric transformations to assess its worth as a chiral auxiliary. ...

Download or read book The Synthesis and an Application of a New Chiral Auxiliary for Organic Synthesis written by Jon Douglas Rainier and published by . This book was released on 1990 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Novel Silicon based Chiral Auxiliary Trans 2 dimethylphenylsilyl cyclohexanol written by Lei Bi and published by . This book was released on 2001 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Development and Applications of a New Chiral Auxiliary written by Keith James Grant and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract; An endo-borneol based oxazolidinone was used in a series of asymmetric transformations to assess its worth as a chiral auxiliary. ...

Download or read book Organostannane Based Chiral Auxiliary Approach to Enantioselective Synthesis written by Margaret A. Soltis and published by . This book was released on 1992 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chiral Auxiliaries and Chirogenesis written by Victor Borovkov and published by Mdpi AG. This book was released on 2021-06-29 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Reprint Book highlights and overviews the most important and novel aspects of chiral auxiliary and chirogenesis in different natural/physical sciences and in modern technologies. In particular, some newly emerging classes of molecules used for these purposes are described. This book consists of four review articles and one research paper and is of interest for general chemistry readership, including graduate and postgraduate students, and for researchers specializing in the fields of chirality and stereochemistry

Download or read book Compendium of Chiral Auxiliary Applications written by Gregory Roos and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chiral Auxiliaries and Substrate Directable Reactions to Access Highly Functionalised Chiral Lactones written by Iwan Rhydian Davies and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis describes the development of chiral auxiliary based methodologies for the asymmetric synthesis of hydroxylated!-lactones and "--Lactones containing multiple contiguous stereocentres. The first chapter introduces the concept of chirality and provides a general overview of the range of strategies available for the preparation of chiral molecules in enantiomerically pure forms. The second chapter critically reviews the range of synthetic methodology that is currently available for the asymmetric synthesis of chiral #-lactones that are either natural products or useful chiral building blocks for synthesis. The third chapter describes the development of novel methodology for the epoxidation/lactonisation of a range of #x1C;-vinyl-syn-aldols to directly afford!-lactones containing up to four contiguous stereocentres in high de. These reactions were shown to proceed via a mechanism whereby hydroxyl-directed diastereoselective epoxidation is followed by intramolecular attack of their!-acyl-oxazolidin-2- one fragment, to directly afford the desired chiral!-lactone. The?self-cleavage? aspect of these reactions was exploited to enable this methodology to be transferred to polymer-support using an immobilised Evans?-oxazolidin-2-one for asymmetric synthesis. Chapter 4 describes the development of a complementary methodology for the asymmetric synthesis of this type of hydroxylated!-lactone based on a strategy involving dihydroxylation of N-acyl-oxazolidin-2-one-#x1C;-vinyl-syn-aldols using catalytic amounts of osmium tetroxide. This methodology was developed as part of a reinvestigation of previously reported dihydroxylation reactions by Dias and coworkers, where we have clearly shown that the stereochemistry of thelactones reported in their paper have been incorrectly assigned. This diastereoselective dihydroxylation methodology has been successfully applied to the asymmetric synthesis of the natural product deoxyribonolactone. Finally, Chapter 5 describes the development of methodology for the asymmetric synthesis of chiral "-lactones containing four contiguous stereocentres of use as potential chiral building blocks for the synthesis of polyketide natural products. In this approach, cyclopropanation of N-acyl-oxazolidin-2-one-#x1C;-vinyl-syn-aldols occurs under the sterodirecting effect of the #x1C;- hydroxyl group to afford cyclopropyl-aldols in very high de. These cyclopropyl-aldols are then ring opened in the presence of mercuric ions, with their N-acyl-oxazolidin-2-one fragment acting as an internal nucleophile, to afford highly functionalised alkyl-mercury species that may be subsequently reduced to afford their corresponding "-lactones in high de.