Download or read book A Mutation selection Model with Recombination for General Genotypes written by Steven Neil Evans and published by . This book was released on 2013 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: We investigate a continuous time, probability measure-valued dynamical system that describes the process of mutation-selection balance in a context where the population is infinite, there may be infinitely many loci, and there are weak assumptions on selective costs. Our model arises when we incorporate very general recombination mechanisms into an earlier model of mutation and selection presented by Steinsaltz, Evans and Wachter in 2005 and take the relative strength of mutation and selection to be sufficiently small. The resulting dynamical system is dynamical system a flow of measures on the space of loci. Each such measure is the intensity measure of a Poisson random measure on the space of loci: intensity measure the points of a realization of the random measure record the set of loci at which the genotype of a uniformly chosen individual differs from a reference wild type due to an accumulation of ancestral mutations. Our motivation for working in such a general setting is to provide a basis for understanding mutation-driven changes in age-specific demographic schedules that arise from the complex interaction of many genes, and hence to develop a framework for understanding the evolution of aging. We establish the existence and uniqueness of the dynamical system, provide conditions for the existence and stability of equilibrium states, and prove that our continuous-time dynamical system is the limit of a sequence of discrete-time infinite population mutation-selection-recombination models in the standard asymptotic regime where selection and mutation are weak relative to recombination and both scale at the same infinitesimal rate in the limit.
Download or read book A Mutation Selection Model with Recombination for General Genotypes written by Steven Neil Evans and published by American Mathematical Soc.. This book was released on 2013-02-26 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors investigate a continuous time, probability measure-valued dynamical system that describes the process of mutation-selection balance in a context where the population is infinite, there may be infinitely many loci, and there are weak assumptions on selective costs. Their model arises when they incorporate very general recombination mechanisms into an earlier model of mutation and selection presented by Steinsaltz, Evans and Wachter in 2005 and take the relative strength of mutation and selection to be sufficiently small. The resulting dynamical system is a flow of measures on the space of loci. Each such measure is the intensity measure of a Poisson random measure on the space of loci: the points of a realization of the random measure record the set of loci at which the genotype of a uniformly chosen individual differs from a reference wild type due to an accumulation of ancestral mutations. The authors' motivation for working in such a general setting is to provide a basis for understanding mutation-driven changes in age-specific demographic schedules that arise from the complex interaction of many genes, and hence to develop a framework for understanding the evolution of aging.
Download or read book The Mathematical Theory of Selection Recombination and Mutation written by R. Bürger and published by John Wiley & Sons. This book was released on 2000-11-02 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: "It is close to being a masterpiece...could well be the classic presentation of the area." Warren J. Ewens, University of Pennsylvania, USA Population genetics is concerned with the study of the genetic, ecological, and evolutionary factors that influence and change the genetic composition of populations. The emphasis here is on models that have a direct bearing on evolutionary quantitative genetics. Applications concerning the maintenance of genetic variation in quantitative traits and their dynamics under selection are treated in detail. * Provides a unified, self-contained and in-depth study of the theory of multilocus systems * Introduces the basic population-genetic models * Explores the dynamical and equilibrium properties of the distribution of quantitative traits under selection * Summarizes important results from more demanding sections in a comprehensible way * Employs a clear and logical presentation style Following an introduction to elementary population genetics and discussion of the general theory of selection at two or more loci, the author considers a number of mutation-selection models, and derives the dynamical equations for polygenic traits under general selective regimes. The final chapters are concerned with the maintenance of quantitative-genetic variation, the response to directional selection, the evolutionary role of deleterious mutations, and other topics. Graduate students and researchers in population genetics, evolutionary theory, and biomathematics will benefit from the in-depth coverage. This text will make an excellent reference volume for the fields of quantitative genetics, population and theoretical biology.
Download or read book Human Evolutionary Demography written by Oskar Burger and published by Open Book Publishers. This book was released on 2024-06-14 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human evolutionary demography is an emerging field blending natural science with social science. This edited volume provides a much-needed, interdisciplinary introduction to the field and highlights cutting-edge research for interested readers and researchers in demography, the evolutionary behavioural sciences, biology, and related disciplines. By bridging the boundaries between social and biological sciences, the volume stresses the importance of a unified understanding of both in order to grasp past and current demographic patterns. Demographic traits, and traits related to demographic outcomes, including fertility and mortality rates, marriage, parental care, menopause, and cooperative behavior are subject to evolutionary processes. Bringing an understanding of evolution into demography therefore incorporates valuable insights into this field; just as knowledge of demography is key to understanding evolutionary processes. By asking questions about old patterns from a new perspective, the volume—composed of contributions from established and early-career academics—demonstrates that a combination of social science research and evolutionary theory offers holistic understandings and approaches that benefit both fields. Human Evolutionary Demography introduces an emerging field in an accessible style. It is suitable for graduate courses in demography, as well as upper-level undergraduates. Its range of research is sure to be of interest to academics working on demographic topics (anthropologists, sociologists, demographers), natural scientists working on evolutionary processes, and disciplines which cross-cut natural and social science, such as evolutionary psychology, human behavioral ecology, cultural evolution, and evolutionary medicine. As an accessible introduction, it should interest readers whether or not they are currently familiar with human evolutionary demography.
Download or read book Non cooperative Equilibria of Fermi Systems with Long Range Interactions written by Jean-Bernard Bru and published by American Mathematical Soc.. This book was released on 2013-06-28 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors define a Banach space $\mathcal{M}_{1}$ of models for fermions or quantum spins in the lattice with long range interactions and make explicit the structure of (generalized) equilibrium states for any $\mathfrak{m}\in \mathcal{M}_{1}$. In particular, the authors give a first answer to an old open problem in mathematical physics--first addressed by Ginibre in 1968 within a different context--about the validity of the so-called Bogoliubov approximation on the level of states. Depending on the model $\mathfrak{m}\in \mathcal{M}_{1}$, the authors' method provides a systematic way to study all its correlation functions at equilibrium and can thus be used to analyze the physics of long range interactions. Furthermore, the authors show that the thermodynamics of long range models $\mathfrak{m}\in \mathcal{M}_{1}$ is governed by the non-cooperative equilibria of a zero-sum game, called here thermodynamic game.
Download or read book Kuznetsov s Trace Formula and the Hecke Eigenvalues of Maass Forms written by Andrew Knightly and published by American Mathematical Soc.. This book was released on 2013-06-28 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors give an adelic treatment of the Kuznetsov trace formula as a relative trace formula on $\operatorname{GL}(2)$ over $\mathbf{Q}$. The result is a variant which incorporates a Hecke eigenvalue in addition to two Fourier coefficients on the spectral side. The authors include a proof of a Weil bound for the generalized twisted Kloosterman sums which arise on the geometric side. As an application, they show that the Hecke eigenvalues of Maass forms at a fixed prime, when weighted as in the Kuznetsov formula, become equidistributed relative to the Sato-Tate measure in the limit as the level goes to infinity.
Download or read book Strange Attractors for Periodically Forced Parabolic Equations written by Kening Lu and published by American Mathematical Soc.. This book was released on 2013-06-28 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors prove that in systems undergoing Hopf bifurcations, the effects of periodic forcing can be amplified by the shearing in the system to create sustained chaotic behavior. Specifically, strange attractors with SRB measures are shown to exist. The analysis is carried out for infinite dimensional systems, and the results are applicable to partial differential equations. Application of the general results to a concrete equation, namely the Brusselator, is given.
Download or read book In the Light of Evolution written by National Academy of Sciences and published by Sackler Colloquium. This book was released on 2007 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.
Download or read book On Some Aspects of Oscillation Theory and Geometry written by Bruno Bianchini and published by American Mathematical Soc.. This book was released on 2013-08-23 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this paper is to analyze some of the relationships between oscillation theory for linear ordinary differential equations on the real line (shortly, ODE) and the geometry of complete Riemannian manifolds. With this motivation the authors prove some new results in both directions, ranging from oscillation and nonoscillation conditions for ODE's that improve on classical criteria, to estimates in the spectral theory of some geometric differential operator on Riemannian manifolds with related topological and geometric applications. To keep their investigation basically self-contained, the authors also collect some, more or less known, material which often appears in the literature in various forms and for which they give, in some instances, new proofs according to their specific point of view.
Download or read book Sociality Hierarchy Health written by National Research Council and published by National Academies Press. This book was released on 2014-09-16 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sociality, Hierarchy, Health: Comparative Biodemography is a collection of papers that examine cross-species comparisons of social environments with a focus on social behaviors along with social hierarchies and connections, to examine their effects on health, longevity, and life histories. This report covers a broad spectrum of nonhuman animals, exploring a variety of measures of position in social hierarchies and social networks, drawing links among these factors to health outcomes and trajectories, and comparing them to those in humans. Sociality, Hierarchy, Health revisits both the theoretical underpinnings of biodemography and the empirical findings that have emerged over the past two decades.
Download or read book Weighted Bergman Spaces Induced by Rapidly Increasing Weights written by Jose Angel Pelaez and published by American Mathematical Soc.. This book was released on 2014-01-08 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is devoted to the study of the weighted Bergman space $A^p_\omega$ of the unit disc $\mathbb{D}$ that is induced by a radial continuous weight $\omega$ satisfying $\lim_{r\to 1^-}\frac{\int_r^1\omega(s)\,ds}{\omega(r)(1-r)}=\infty.$ Every such $A^p_\omega$ lies between the Hardy space $H^p$ and every classical weighted Bergman space $A^p_\alpha$. Even if it is well known that $H^p$ is the limit of $A^p_\alpha$, as $\alpha\to-1$, in many respects, it is shown that $A^p_\omega$ lies ``closer'' to $H^p$ than any $A^p_\alpha$, and that several finer function-theoretic properties of $A^p_\alpha$ do not carry over to $A^p_\omega$.
Download or read book Relative Equilibria in the 3 Dimensional Curved n Body Problem written by Florin Diacu and published by American Mathematical Soc.. This book was released on 2014-03-05 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considers the 3 -dimensional gravitational n -body problem, n32 , in spaces of constant Gaussian curvature k10 , i.e. on spheres S 3 ?1 , for ?>0 , and on hyperbolic manifolds H 3 ?1, for ?
Download or read book Nonlinear Stability of Ekman Boundary Layers in Rotating Stratified Fluids written by Hajime Koba and published by American Mathematical Soc.. This book was released on 2014-03-05 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: A stationary solution of the rotating Navier-Stokes equations with a boundary condition is called an Ekman boundary layer. This book constructs stationary solutions of the rotating Navier-Stokes-Boussinesq equations with stratification effects in the case when the rotating axis is not necessarily perpendicular to the horizon. The author calls such stationary solutions Ekman layers. This book shows the existence of a weak solution to an Ekman perturbed system, which satisfies the strong energy inequality. Moreover, the author discusses the uniqueness of weak solutions and computes the decay rate of weak solutions with respect to time under some assumptions on the Ekman layers and the physical parameters. The author also shows that there exists a unique global-in-time strong solution of the perturbed system when the initial datum is sufficiently small. Comparing a weak solution satisfying the strong energy inequality with the strong solution implies that the weak solution is smooth with respect to time when time is sufficiently large.
Download or read book Stochastic Flows in the Brownian Web and Net written by Emmanuel Schertzer and published by American Mathematical Soc.. This book was released on 2014-01-08 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is known that certain one-dimensional nearest-neighbor random walks in i.i.d. random space-time environments have diffusive scaling limits. Here, in the continuum limit, the random environment is represented by a `stochastic flow of kernels', which is a collection of random kernels that can be loosely interpreted as the transition probabilities of a Markov process in a random environment. The theory of stochastic flows of kernels was first developed by Le Jan and Raimond, who showed that each such flow is characterized by its -point motions. The authors' work focuses on a class of stochastic flows of kernels with Brownian -point motions which, after their inventors, will be called Howitt-Warren flows. The authors' main result gives a graphical construction of general Howitt-Warren flows, where the underlying random environment takes on the form of a suitably marked Brownian web. This extends earlier work of Howitt and Warren who showed that a special case, the so-called "erosion flow", can be constructed from two coupled "sticky Brownian webs". The authors' construction for general Howitt-Warren flows is based on a Poisson marking procedure developed by Newman, Ravishankar and Schertzer for the Brownian web. Alternatively, the authors show that a special subclass of the Howitt-Warren flows can be constructed as random flows of mass in a Brownian net, introduced by Sun and Swart. Using these constructions, the authors prove some new results for the Howitt-Warren flows.
Download or read book A Complete Classification of the Isolated Singularities for Nonlinear Elliptic Equations with Inverse Square Potentials written by Florica C. Cîrstea and published by American Mathematical Soc.. This book was released on 2014-01-08 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: In particular, for b = 1 and λ = 0, we find a sharp condition on h such that the origin is a removable singularity for all non-negative solutions of [[eqref]]one, thus addressing an open question of Vázquez and Véron.
Download or read book Large Deviations for Additive Functionals of Markov Chains written by Alejandro D. de Acosta and published by American Mathematical Soc.. This book was released on 2014-03-05 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
