Download or read book Clinical Trials written by Steven Piantadosi and published by John Wiley & Sons. This book was released on 2017-10-09 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents elements of clinical trial methods that are essential in planning, designing, conducting, analyzing, and interpreting clinical trials with the goal of improving the evidence derived from these important studies This Third Edition builds on the text’s reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for clinical trials. Readers will encounter the principles of design for various types of clinical trials, and are then skillfully guided through the complete process of planning the experiment, assembling a study cohort, assessing data, and reporting results. Throughout the process, the author alerts readers to problems that may arise during the course of the trial and provides common sense solutions. All stages of therapeutic development are discussed in detail, and the methods are not restricted to a single clinical application area. The authors bases current revisions and updates on his own experience, classroom instruction, and feedback from teachers and medical and statistical professionals involved in clinical trials. The Third Edition greatly expands its coverage, ranging from statistical principles to new and provocative topics, including alternative medicine and ethics, middle development, comparative studies, and adaptive designs. At the same time, it offers more pragmatic advice for issues such as selecting outcomes, sample size, analysis, reporting, and handling allegations of misconduct. Readers familiar with the First and Second Editions will discover revamped exercise sets; an updated and extensive reference section; new material on endpoints and the developmental pipeline, among others; and revisions of numerous sections. In addition, this book: • Features accessible and broad coverage of statistical design methods—the crucial building blocks of clinical trials and medical research -- now complete with new chapters on overall development, middle development, comparative studies, and adaptive designs • Teaches readers to design clinical trials that produce valid qualitative results backed by rigorous statistical methods • Contains an introduction and summary in each chapter to reinforce key points • Includes discussion questions to stimulate critical thinking and help readers understand how they can apply their newfound knowledge • Provides extensive references to direct readers to the most recent literature, and there are numerous new or revised exercises throughout the book Clinical Trials: A Methodologic Perspective, Third Edition is a textbook accessible to advanced undergraduate students in the quantitative sciences, graduate students in public health and the life sciences, physicians training in clinical research methods, and biostatisticians and epidemiologists. This book is accompanied by downloadable files available below under the DOWNLOADS tab. These files include: MATHEMATICA program – A set of downloadable files that tracks the chapters, containing code pertaining to each. SAS PROGRAMS and DATA FILES used in the book. The following software programs, included in the downloadables, were developed by the author, Steven Piantadosi, M.D., Ph.D: RANDOMIZATION – This program generates treatment assignments for a clinical trial using blocked stratified randomization. CRM – Implements the continual reassessment methods for dose finding clinical trials. OPTIMAL – Calculates two-stage optimal phase II designs using the Simon method. POWER – This is a power and sample size program for clinical trials. Executables for installing these programs can also be found at https://risccweb.csmc.edu/biostats/. Steven Piantadosi, MD, PhD, is the Phase One Foundation Distinguished Chair and Director of the Samuel Oschin Cancer Institute, and Professor of Medicine at Cedars-Sinai Medical Center in Los Angeles, California. Dr. Piantadosi is one of the world’s leading experts in the design and analysis of clinical trials for cancer research. He has taught clinical trials methods extensively in formal courses and short venues. He has advised numerous academic programs and collaborations nationally regarding clinical trial design and conduct, and has served on external advisory boards for the National Institutes of Health and other prominent cancer programs and centers. The author of more than 260 peer-reviewed scientific articles, Dr. Piantadosi has published extensively on research results, clinical applications, and trial methodology. While his papers have contributed to many areas of oncology, he has also collaborated on diverse studies outside oncology including lung disease and degenerative neurological disease.
Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1995 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lists citations with abstracts for aerospace related reports obtained from world wide sources and announces documents that have recently been entered into the NASA Scientific and Technical Information Database.
Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1972-11 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Literature Search written by National Library of Medicine (U.S.) and published by . This book was released on 1967 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physics Volume 2 written by John D. Cutnell and published by John Wiley & Sons. This book was released on 2021-10-05 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the newly revised Twelfth Edition of Physics: Volume 2, an accomplished team of physicists and educators delivers an accessible and rigorous approach to the skills students need to succeed in physics education. Readers will learn to understand foundational physics concepts, solve common physics problems, and see real-world applications of the included concepts to assist in retention and learning. The text includes Check Your Understanding questions, Math Skills boxes, multi-concept problems, and worked examples. The second volume of a two-volume set, Volume 2 explores ideas and concepts like the reflection, refraction, and wave-particle duality of light. Throughout, students knowledge is tested with concept and calculation problems and team exercises that focus on cooperation and learning.
Download or read book World Congress of Medical Physics and Biomedical Engineering 2006 written by Sun I. Kim and published by Springer Science & Business Media. This book was released on 2007-05-07 with total page 4361 pages. Available in PDF, EPUB and Kindle. Book excerpt: These proceedings of the World Congress 2006, the fourteenth conference in this series, offer a strong scientific program covering a wide range of issues and challenges which are currently present in Medical physics and Biomedical Engineering. About 2,500 peer reviewed contributions are presented in a six volume book, comprising 25 tracks, joint conferences and symposia, and including invited contributions from well known researchers in this field.
Download or read book Fundamentals of Aerospace Medicine written by Jeffrey R. Davis, M.D. and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its Fourth Edition with a new editorial team, this comprehensive text addresses all medical and public health issues involved in the care of crews, passengers, and support personnel of aircraft and space vehicles. Coverage includes human physiology under flight conditions, clinical medicine in the aerospace environment, and the impact of the aviation industry on global public health. This edition features new chapters on radiation, toxicology and microbiology, dental considerations in aerospace medicine, women's health issues, commercial human space flight, space exploration, and unique aircraft including parachuting. Other highlights include significant new information on respiratory diseases, cardiovascular medicine, infectious disease transmission, and human response to acceleration.
Download or read book Contemporary IMRT written by S. Webb and published by CRC Press. This book was released on 2019-06-14 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most important radiotherapy modality used today, intensity modulated radiation therapy (IMRT), is the most technologically advanced radiotherapy cancer treatment available, rapidly replacing conformal and three-dimensional techniques. Because of these changes, oncologists and radiotherapists need up-to-date information gathered by physicists an
Download or read book The Physics of Conformal Radiotherapy written by S. Webb and published by CRC Press. This book was released on 1997-01-01 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Physics of Conformal Radiotherapy: Advances in Technology provides a thorough overview of conformal radiotherapy and biological modeling, focusing on the underlying physics and methodology of three-dimensional techniques in radiation therapy. This carefully written, authoritative account evaluates three-dimensional treatment planning, optimization, photon multileaf collimation, proton therapy, transit dosimetry, intensity-modulation techniques, and biological modeling. It is an invaluable teaching guide and reference for all medical physicists and radiation oncologists/therapists that use conformal radiotherapy.
Download or read book Veterinary Anesthesia and Analgesia written by Kurt Grimm and published by John Wiley & Sons. This book was released on 2015-03-16 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Anesthesia and Analgesia: the Fifth Edition of Lumb and Jones is a reorganized and updated edition of the gold-standard reference for anesthesia and pain management in veterinary patients. Provides a thoroughly updated edition of this comprehensive reference on veterinary anesthesia and analgesia, combining state-of-the-art scientific knowledge and clinically relevant information Covers immobilization, sedation, anesthesia, and analgesia of companion, wild, zoo, and laboratory animals Takes a body systems approach for easier reference to information about anesthetizing patients with existing conditions Adds 10 completely new chapters with in-depth discussions of perioperative heat balance, coagulation disorders, pacemaker implantation, cardiac output measurement, cardiopulmonary bypass, shelter anesthesia and pain management, anesthetic risk assessment, principles of anesthetic pharmacology, and more Now printed in color, with more than 400 images
Download or read book Nonlinear Analysis written by Qamrul Hasan Ansari and published by Springer. This book was released on 2014-06-05 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of our daily-life problems can be written in the form of an optimization problem. Therefore, solution methods are needed to solve such problems. Due to the complexity of the problems, it is not always easy to find the exact solution. However, approximate solutions can be found. The theory of the best approximation is applicable in a variety of problems arising in nonlinear functional analysis and optimization. This book highlights interesting aspects of nonlinear analysis and optimization together with many applications in the areas of physical and social sciences including engineering. It is immensely helpful for young graduates and researchers who are pursuing research in this field, as it provides abundant research resources for researchers and post-doctoral fellows. This will be a valuable addition to the library of anyone who works in the field of applied mathematics, economics and engineering.
Download or read book Statistical Applications from Clinical Trials and Personalized Medicine to Finance and Business Analytics written by Jianchang Lin and published by Springer. This book was released on 2016-11-13 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers in this volume represent a broad, applied swath of advanced contributions to the 2015 ICSA/Graybill Applied Statistics Symposium of the International Chinese Statistical Association, held at Colorado State University in Fort Collins. The contributions cover topics that range from statistical applications in business and finance to applications in clinical trials and biomarker analysis. Each papers was peer-reviewed by at least two referees and also by an editor. The conference was attended by over 400 participants from academia, industry, and government agencies around the world, including from North America, Asia, and Europe.
Download or read book The Physics of Three Dimensional Radiation Therapy written by S. Webb and published by CRC Press. This book was released on 1993-01-01 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Physics of Three Dimensional Radiation Therapy presents a broad study of the use of three-dimensional techniques in radiation therapy. These techniques are used to specify the target volume precisely and deliver radiation with precision to minimize damage to surrounding healthy tissue. The book discusses multimodality computed tomography, complex treatment planning software, advanced collimation techniques, proton radiotherapy, megavoltage imaging, and stereotactic radiosurgery. A review of the literature, numerous questions, and many illustrations make this book suitable for teaching a course. The themes covered in this book are developed and expanded in Webb's The Physics of Conformal Radiotherapy and the two may be used together or in successive semesters for teaching purposes.
Download or read book Host Bibliographic Record for Boundwith Item Barcode 30112085295688 written by and published by . This book was released on 1907 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Pill Book 13th Edition written by Harold M. Silverman and published by Bantam. This book was released on 2009-09-23 with total page 1296 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than two decades, millions of consumers have trusted The Pill Book to provide official, FDA-approved drug information plus guidelines from leading pharmacists. Each drug is profiled in a concise, readable, and easy-to-understand entry, making The Pill Book the perfect reference when you have questions about the medications your doctor prescribes. The most up-to-date information about the more than 1,800 most commonly prescribed drugs in the United States: • Generic and brand-name listings that can help you save money • What the drug is for, and how it works • Usual dosages, and what to do if a dose is skipped • Side effects and possible adverse reactions, highlighted for quick reference • Interactions with other drugs and food • Overdose and addiction potential • Alcohol-free and sugar-free medications • The most popular self-injected medications and their safe handling • Information for seniors, pregnant and breast-feeding women, children, and others with special needs • Cautions and warnings, and when to call your doctor • 32 pages of actual-size color photographs of prescription pills
Download or read book The Pill Book 14th Edition written by Harold M. Silverman and published by Bantam. This book was released on 2011-07-20 with total page 1382 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE CONSUMER’S GUIDE TO PILLS—COMPLETELY REVISED 14th EDITION FOR 2010 WITH MORE THAN 20 IMPORTANT NEW DRUGS AND DOZENS OF NEW BRAND NAMES For more than three decades, millions of consumers have trusted The Pill Book to provide official, FDA-approved information on more than 1,800 of the most commonly prescribed drugs in the United States with guidelines from leading pharmacists. Each drug is profiled in a concise, readable, easy-to-understand entry, making The Pill Book the perfect reference when you have questions about the medications your doctor prescribes. Inside you’ll discover • generic and brand-name listings that can help you save money • What each drug is for, and how it works • usual dosages, and what to do if a dose is skipped • side effects and possible adverse reactions, highlighted for quick reference • interactions with other drugs and food • overdose and addiction potential • alcohol-free and sugar-free medications • the most popular self-injected medications and their safe handling • information for seniors, pregnant and breast-feeding women, children, and others with special needs • cautions and warnings, and when to call your doctor • 32 pages of actual-size color photographs of prescription pills* No home should be without this book! *Not all ereading devices will show the images in color and at the exact size.
Download or read book Medical Application and Radiobiology Research of Particle Radiation written by Fei Ye and published by Frontiers Media SA. This book was released on 2022-08-25 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt:
